Negative / Null Result ReportOpen accessMedicine
Nilgün Solmaz, Onur Yaya, Feyza Önder · 2014 · Türk Oftalmoloji Dergisi
Objectives: Evaluation of structural alterations of the optic nerve head (ONH) and the retinal nerve fiber layer (RNFL) in patients with ocular hypertension (OHT) and early-stage glaucoma and assessment of the discriminatory diagnostic performance of spectral-domain optical coherence tomography (SD-OCT) Copernicus (Optopol Technology S.A.). Materials and Methods: This study included 59 eyes of a total of 59 patients, 29 of whom were diagnosed with OHT (Group 1) and 30 with early-stage glaucoma (Group 2). The differentiation of early-stage glaucoma and OHT was carried out on the basis of standa
View details →DOI: 10.4274/tjo.71677 Negative / Null Result ReportOpen accessScience (General)
Fenise Selin Karali, Samet Tosun, Meltem Şen-Aksüt et al. · 2024 · Heliyon
Cyberloafing is the use of (e.g. smartphones, tablets, laptops, and the Internet) for purposes other than work related reasons during work hours. Although cyberloafing in the workplace has been widely investigated, there is relatively a small number of studies on cyberloafing behaviors in educational settings, which refer to students' tendencies to use technology for non-class-related purposes during lectures. The goal of the current study is to determine how frequently and for what purposes speech and language therapy (SLT) students at Biruni University engage in cyberloafing during lectures.
View details →DOI: 10.1016/j.heliyon.2024.e31068 Negative / Null Result ReportOpen accessGynecology and obstetrics
Fariba Mousavi, Sakineh Mohammad-Alizadeh-Charandabi, Mojgan Mirgafourvand et al. · 2023 · Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Introduction: Early symptoms of menopause are very common and often very bothersome. Considering the increasing number of women experiencing these symptoms in the world and Iran, there is a growing need to use methods to reduce these symptoms. Therefore, this study was performed with aim to determine the effect of the combined herbal capsules (Menohelp) on reducing the early symptoms of menopause, number and intensity of hot flashes (primary outcomes), and improving sleep quality and quality of life (secondary outcomes) in menopausal women. Methods: In this double-blind trial in Tabriz, 100 wo
View details →DOI: 10.22038/ijogi.2023.22601 Negative / Null Result ReportOpen accessDentistry
Ebrahim Amin Salehi, Haleh Heshmat, Elham Moravej Salehi et al. · 2013 · Journal of Islamic Dental Association of Iran
Background and Aim: Intraoral repair of fractured porcelain is an acceptable method to avoid replacement and therefore saving time and cost. The purpose of this study was to determine the in-vitro shear bond strengths of composite resin to feldspathic porcelain after different durations of sandblasting and to compare the effect of sandblasting with that of hydrofluoric acid (HF ). Materials and Methods : In this in-vitro study, 40 porcelain disks were fabricated and randomly divided into 4 groups (n=10). Porcelain surface in group 1 was etched with 9.5% HF for 2 minutes. Groups 2, 3 and 4 were
Negative / Null Result ReportOpen accessMedicine
Olvera-Maneu S, Regidor M, Serres-Corral P et al. · 2026 · Animals : an open access journal from MDPI
Fecal glucocorticoid metabolites (FGM) are widely used to assess hypothalamic-pituitary-adrenal (HPA) activity in vertebrates, but their applicability to reptiles, and more specifically to snakes, remains poorly explored. The objective of…
View details →DOI: 10.3390/ani16101485 Negative / Null Result ReportOpen accessMedical emergencies. Critical care. Intensive care. First aid
Irfan Zubair Shahul Hameed, Darpanarayan Hazra, Priya Ganesan et al. · 2024 · Turkish Journal of Emergency Medicine
OBJECTIVES: In the context of acute hypoxemic respiratory failure (AHRF), ensuring effective preoxygenation and apneic oxygenation emerges as the pivotal approach ensuring for averting hypoxemic adverse events during endotracheal intubation. To investigate this, we conducted an open-label randomized controlled trial, aiming to assess the comparative effectiveness of nasopharyngeal high-flow oxygenation in conjunction with Bag-Valve-Mask (BVM) versus standard BVM preoxygenation in patients experiencing AHRF within the emergency department (ED). METHODS: This prospective single-center, open-labe
View details →DOI: 10.4103/tjem.tjem_176_23 Negative / Null Result ReportOpen accessMedicine
Pola farhad hassan, Hamdia Mirkhan Ahmed · 2019 · Diyala Journal of Medicine
Background: Benefits of minimally invasive or laparoscopic procedures include less post operative discomfort. Objective: This study aimed to identify the early postoperative complications of laparscopic cholecystectomy and their association with age, occupation and previous laparatomy. Patients and Methods: 60 female patients diagnosed with having symptomatic gallstone underwent laparscopic cholecystectomy in Pirmam General Hospital, during the period from Jan 2015 to Jul 2015. Surgery done by researchers and after 10 days, the patient interviewed and examined for finding the complications, th
Negative / Null Result ReportOpen accessMedicine (General)
Seyed Hosein Tabatabaei, Seyed Mehdi Kalantar, Mohammad Hasan Akhavan Karbassi et al. · 2021 · Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Considering the importance of oral health as a part of general health and the role of physicians in community health, the present study was conducted to investigate the relationship between common oral diseases and general body health from the perspective of medical students in Yazd City in 2018. Methods: In this descriptive cross-sectional study, 210 internship and pre-internship students of Shahid Sadoughi University of Medical Sciences in Yazd Cityin 2018 were selected randomly and their knowledge about common oral and dental diseases and its relationship with general body hea
Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Fereshteh Baygi, Mostafa Qorbani, Mohammad Esmaeil Motlagh et al. · 2020 · BMC Cardiovascular Disorders
Abstract Background This study evaluated the association of frequency of potato and rice consumption with cardiometabolic risk factors in children and adolescents. Methods This nationwide cross-sectional survey was conducted on 14,400 children and adolescents. Fasting blood was obtained from a sub-sample of 4200 randomly selected students. Physical examination and laboratory tests were conducted under standard protocols. Metabolic Syndrome (Mets) was defined based on the Adult Treatment Panel III criteria modified for the pediatric age group. The self-reported frequency consumption of white ri
View details →DOI: 10.1186/s12872-020-01524-y Negative / Null Result ReportOpen accessMedicine
Xuetao Zhu, Yixiang Zhao, Kaiwen Liu et al. · 2024 · Scientific Reports
Abstract To compare the clinical efficacy of interlaminar endoscopic surgical system delta (iLESSYS-Delta) discectomy with that of classical fenestration discectomy for treating lumbar disc herniation. Patients who underwent iLESSYS-Delta or fenestration discectomy were enrolled in this study. Baseline information and clinical indicators were collected. The baseline data were matched using propensity score matching. Fifty-two patients were in each group. In the iLESSYS-Delta cohort, the volume of intraoperative bleeding was 18.17 ± 4.20 ml, the length of postoperative hospital stay was 4.16 ±
View details →DOI: 10.1038/s41598-024-70973-8 Negative / Null Result Report
Caldana M, Rusconi E · 2026 · Preprint
Olfaction is one of our most archaic senses but its central mechanisms are lesser known than those of other senses. In this work, we address a possible link between olfactory stimuli and mental spatial representations. Although olfactory…
View details →DOI: 10.31234/osf.io/nk3ty_v3 Negative / Null Result ReportOpen accessNursing
Nora Kasparaitytė, Juozas Raistenskis, Lina Budrienė et al. · 2025 · Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija
Background. Idiopathic scoliosis is among the most common spinal disorders diagnosed in 1–3% of children and adolescents. Treatment choice is related to disease severity, with a Cobb angle of 20–40°, a corrective brace or physiotherapy can stop its progression. However, insufficient research has shown whether combined treatment is better than monotherapy. Aim. To evaluate the effect of combining bracing and physiotherapy to reduce spinal deformity, improve quality of life and lung function, and compare the results with those of monotherapy. Determine the optimal duration of combined rehabilit
View details →DOI: 10.33607/rmske.v1i32.1603 Negative / Null Result ReportOpen accessPlant culture
Carlos I. Cortés-Martínez, Adriana Ines Rodríguez-Hernández, Ma del Rocío López-Cuellar et al. · 2023 · Plant Protection Science
Steinernema glaseri is a potential biocontrol agent against white grubs of the Phyllophaga spp. complex; however, its suitability for in vitro multiplication has been scarcely investigated. In this study, the effects of the surface culture of NJ-43 strain with its symbiotic bacteria Xenorhabdus poinarii on egg-yolk agar (P2), chicken-liver agar and nutrient meat-peptone (MP) agar on infective juvenile (IJ) productivity and their virulence against Galleria mellonella larvae were investigated. The bacteria on the surface of the agar were first incubated in darkness at 30 °C for 54-102 h, and the
View details →DOI: 10.17221/1/2023-pps Negative / Null Result ReportOpen accessMedicine
Fereshteh Baygi, Theis Bitz Trabjerg, Lars Henrik Jensen et al. · 2025 · JMIR Formative Research
BackgroundEnhancing care coordination and sharing information in cancer care improves patient experiences by promoting clarity and satisfaction. ObjectiveThis study aims to assess the impact of cross-sectoral video consultation on patient perceptions of care coordination and satisfaction with received information compared to usual care. MethodsThis study presents secondary outcomes on patient perceptions of care coordination and satisfaction with received information from a 7-month follow-up of the Partnership Project. In this randomized controlled trial, patients with cancer were allocated to
View details →DOI: 10.2196/76910 Negative / Null Result ReportOpen accessVeterinary medicine
Masato Katayama, Yukina Uemura · 2026 · Veterinary Sciences
Background: Feline chronic gingivostomatitis (FCGS) is refractory stomatitis in cats. The cure rate of tooth extraction selected as a primary surgical treatment is insufficient. Methods: 52 FCGS-suspected cats, including 22 tooth-extracted and 30 unextracted cats, were studied. Commercially available antiviral and antibacterial agents were orally administered as initial treatment, followed by the antiviral agent solely as maintenance therapy. We examined the influence of prior tooth extraction on the therapeutic efficacy of these two drugs by analyzing changes in some physical signs and clinic
View details →DOI: 10.3390/vetsci13040363 Negative / Null Result ReportOpen accessPublic aspects of medicine
Éva Bíró, Ferenc Vincze, Gabriella Mátyás et al. · 2021 · Frontiers in Public Health
Background: The public health relevance of health literacy is highlighted by the fact that its higher levels can improve health outcomes and reduce health inequities. In order to design effective interventions for improving health literacy, the relationship between health literacy and other factors such as sociodemographic variables, subjective health and social support must be understood.Objective: Our aim was to test a socioecological model of the determinants of health literacy with a special focus on the effect of residence. Our study investigated geographical differences regarding the lev
View details →DOI: 10.3389/fpubh.2021.724995 Negative / Null Result ReportOpen accessSurgery
J. Wong, K.F. Lee, P.S.F. Lee et al. · 2009 · Asian Journal of Surgery
Radiofrequency ablation (RFA) has been widely applied for the treatment of hepatocellular carcinoma and liver metastases. The reported mortality and morbidity rates are low. The aim of this study is to evaluate the safety and efficacy of RFA, and compare the results performed percutaneously versus surgically. Patients and Methods: From 2003 to 2006, 79 patients with hepatic malignancies (59 hepatocellular carcinoma, 20 liver metastases) with a total of 110 lesions underwent RFA in our centre. Post-ablation assessment by CT scan was performed in all patients at 1-, 3- and 6-month intervals. Pos
View details →DOI: 10.1016/s1015-9584(09)60003-8 Negative / Null Result ReportOpen accessSpecialties of internal medicine
Ahmad Safapour, Arash Alghasi, Farhad Abolnezhadian · 2021 · Journal of Preventive Epidemiology
Introduction: Immune thrombocytopenic purpura (ITP) is known as the most important cause of sudden drop in platelet count among children. The acute form of unexpected drop in platelet count in children calls for treatment with medications such as corticosteroids, intravenous immunoglobulin (IVIg), and Rho(D) immunoglobulin (anti-DIG). Most of the previous studies have accordingly compared short-term therapeutic outcomes of steroids with those of IVIg. In some cases, IVIg has led to better results. However, there are few studies on the long-term treatment effects of both medicine categories. Ob
View details →DOI: 10.34172/jpe.2021.03 Negative / Null Result ReportOpen accessAgriculture (General)
Monalisa Pereira Dutra, Giselle Pereira Cardoso, Eduardo Mendes Ramos et al. · 2012 · Ciência e Agrotecnologia
The use of liquid whey to replace water (at 0, 25, 50, 75 or 100%) in a restructured cooked ham formulation was studied and several technological and sensory quality properties were determined. The test results showed no statistically significant differences (P 0.05) less reddish (a* value reduction) and more grayish and yellowish (lesser C* and higher h values) with higher whey additions. A lower (P 0.05). These results suggest that up to 38% natural fresh liquid whey can be added to a restructured cooked ham formulation with similar results to products cured with a conventional formulation.
View details →DOI: 10.1590/s1413-70542012000100011 Negative / Null Result ReportOpen accessMedical physics. Medical radiology. Nuclear medicine
Yu Gao, Stephanie Yoon, Ting Martin Ma et al. · 2024 · Physics and Imaging in Radiation Oncology
Background and purpose: Magnetic Resonance Imaging (MRI)-guided Stereotactic body radiotherapy (SBRT) treatment to prostate bed after radical prostatectomy has garnered growing interests. The aim of this study is to evaluate intra-fractional anatomic and dose/volume metric variations for patients receiving this treatment. Materials and methods: Nineteen patients who received 30–34 Gy in 5 fractions on a 0.35T MR-Linac were included. Pre- and post-treatment MRIs were acquired for each fraction (total of 75 fractions). The Clinical Target Volume (CTV), bladder, rectum, and rectal wall were conto
View details →DOI: 10.1016/j.phro.2024.100573 Negative / Null Result ReportOpen accessScience
Ákos Bérczi, Fanni Éva Szablics, Anita Nelli Simon et al. · 2025 · Life
Digital subtraction angiography (DSA) remains an important reference modality for evaluating chronic limb-threatening ischemia (CLTI), with left transradial access (TRA) increasingly favored for its lower complication rates and patient comfort. Radiation safety for operators is paramount, yet the impact of patient positioning on scatter radiation during lower limb diagnostic catheter angiography (CA) is understudied. This single-center randomized controlled trial evaluated whether head-first (HF) vs. feet-first (FF) supine patient orientation affects operator radiation exposure during lower ex
View details →DOI: 10.3390/life15091433 Negative / Null Result ReportOpen accessNutrition. Foods and food supply
Maria Góis, Patrícia Batista, Magnólia Araújo et al. · 2023 · Beverages
Probiotic products have been the focus of research for several years due to the potential of their biological properties to impact mental health, mood, and cognitive functions. Kombucha is a probiotic drink that has been reported to be beneficial for mental health, particularly at the level of emotion regulation. This study aims to understand the perception of the Portuguese and Brazilian populations regarding the consumption of probiotics and Kombucha, as well as to understand these consumers’ perceptions related to the impact on emotion regulation (and the impact of this consumption on emoti
View details →DOI: 10.3390/beverages9030061 Negative / Null Result ReportOpen accessMedicine
Anthime Flaus, Armand Pattée, Guillaume Criton et al. · 2026 · Scientific Reports
Abstract [11C]Methionine ([11C]MET) PET provides high sensitivity to localize corticotroph pituitary neuroendocrine tumors (PitNETs) in de novo Cushing’s disease but remains inconclusive in up to 20% of cases. Current PET protocols rely on late acquisitions (20–40 min post-injection). Since other endocrine tumors present earlier peak tracer uptake, corticotroph PitNETs might also exhibit early differential amino acid uptake, compared to the normal pituitary gland. This exploratory study based on data derived from a previously registered prospective multicenter cohort study (ClinicalTrials.gov
View details →DOI: 10.1038/s41598-026-39219-7 Negative / Null Result ReportOpen accessMedicine
Amirsaeed Hosseini, Mohammad Yousofpour, Faranak Zaker et al. · 2026 · Journal of Mazandaran University of Medical Sciences
Background and purpose: Osteoarthritis is the most common cause of knee pain and has various treatment modalities. The Ferfion plant is a significant medicinal plant in traditional medicine used worldwide. This study aimed to investigate the effect of Ferfion herbal ointment on the clinical symptoms of patients with primary knee osteoarthritis. Materials and methods: This double-blind, randomized clinical trial was conducted on 50 patients with primary knee osteoarthritis at Baghban Clinic. Patients were divided into two groups of 25, receiving either Ferfion ointment or a placebo. The first g
Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Michael Christian Leitner, Michael Christian Leitner, Michael Christian Leitner et al. · 2023 · Frontiers in Neurology
IntroductionA significant number of Restitution Training (RT) paradigms claim to ameliorate visual field loss after stroke by re-activating neuronal connections in the residual visual cortex due to repeated bright light-stimulation at the border of the blind and intact fields. However, the effectiveness of RT has been considered controversial both in science and clinical practice for years. The main points of the controversy are (1) the reliability of perimetric results which may be affected by compensatory eye movements and (2) heterogeneous samples consisting of patients with visual field de
View details →DOI: 10.3389/fneur.2023.1114718 Negative / Null Result ReportOpen accessPharmaceutical industry
Gabriela Rister Figueiredo Irie, Marly Aparecida Spadotto Balarin, Mariangela Torreglosa Ruiz-Cintra et al. · 2016 · Revista de Ciências Farmacêuticas Básica e Aplicada
Endometriosis is a chronic gynecological disease that displays some features similar to malignancy, such as local invasion, aggressive spread to distant organs and angiogenesis. Polymorphisms of the ACE gene have been linked with some vascular disease. To determine the frequency of the ACE I/D polymorphism in Brazilian patients with endometriosis compared to controls. This case-control study included a total of 134 women (49 endometriosis patients and 85 controls) who had undergone a laparoscopy or laparotomy. Molecular analysis was performed by polymerase chain reaction (PCR). For the statist
Negative / Null Result ReportOpen accessMedicine
Meera Niranjan Khadilkar, Nitin Ankle, Sheetal Harakuni · 2017 · Bengal Journal of Otolaryngology and Head Neck Surgery
Introduction Controversy regarding treatment of tonsillitis based on throat culture report still persists. If surface culture is a determinant of bacteriology of the core, then rational therapy could be aimed at organisms cultured by surface swab. Materials and Methods A Cross-sectional study was conducted on 100 patients of chronic tonsillitis who underwent tonsillectomy. Tonsil surface and core swabs were studied for aerobic and anaerobic growth. Result Eighty seven percent patients had aerobic growth on tonsil surface and ninety percent in tonsil core. Staphylococcus aureus was the commones
Negative / Null Result ReportOpen accessMedicine
Jinmann Chon, Hee-Sang Kim, Jong Ha Lee et al. · 2018 · Annals of Rehabilitation Medicine
ObjectiveTo evaluate the association between balance function and asymmetry of knee extension strength in an elderly Korean population.MethodsThe strength of the knee extensors in each leg was measured in 306 community-dwelling elderly subjects (age, 76.70±4.85 years) and 25 young healthy subjects (age, 34.23±8.93 years). Based on the difference in strength of both legs, the elderly subjects were divided into symmetric (n=128) and asymmetric (n=178) strength groups using an asymmetry cutoff 20%. We determined the postural control ability of the subjects using InBody posturography, Berg Balance
View details →DOI: 10.5535/arm.2018.42.1.113 Negative / Null Result ReportOpen accessOtorhinolaryngology
Iqra Zakir, Ahmad Ahmad, Hamdan Pasha et al. · 2022 · Iranian Journal of Otorhinolaryngology
Introduction:Tympanoplasty is a common surgery for chronic otitis media and has conventionally been performed with a microscope for decades. The trend of endoscopic minimally invasive surgeries has been increasing worldwide for the last few decades. Few studies have discussed the outcomes of microscopic and endoscopic tympanoplasty. This study aims to compare results of tympanoplasty done with microscope vs endoscope in terms of graft take rate and improvement in conductive hearing loss.Materials and Methods:We did a retrospective review of 120 patients (54 male and 66 female) who underwent Ty
View details →DOI: 10.22038/ijorl.2022.61234.3104 Negative / Null Result ReportOpen accessBiotechnology
Katja Oberhofer, Patrick D. Wettenschwiler, Navrag Singh et al. · 2018 · Applied Bionics and Biomechanics
The introduction of hip belts to backpacks has caused a shift of loading from the spine to the hips with reported improvements in musculoskeletal comfort. Yet the effects of different hip belt tensions on gait biomechanics remain largely unknown. The goal of this study was to assess the influence of backpack weight and hip belt tension on gait biomechanics. Data from optical motion capture and ground reaction forces (GRF) during walking were acquired in nine healthy male subjects (age 28.0 ± 3.9 years). Six configurations of a commercial backpack were analyzed, that is, 15 kg, 20 kg, and 25 kg
View details →DOI: 10.1155/2018/4671956 