Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Nilsson KF, Goździk W, Frostell C et al. · 2018 · Drug Design, Development and Therapy
Kristofer F Nilsson,1,2 Waldemar Goździk,3 Claes Frostell,4 Stanisław Zieliński,3 Marzena Zielińska,3 Kornel Ratajczak,5 Piotr Skrzypczak,5 Sylwia Rodziewicz,5 Johanna Albert,6 Lars E Gustafsson1,† 1Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden; 2Department of Cardiothoracic and Vascular Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden; 3Department of Anaesthesiology and Intensive Therapy, Wroclaw Medical University, Wroclaw, Poland; 4Department of Anesthesia and Intensive Care, Danderyd Hospital, Stockholm, Swede
Negative / Null Result ReportOpen accessDentistry
Sareh Habibzadeh, Solmauz Eskandarion, Seyed Mahmoud Amin Marashi et al. · 2021 · Frontiers in Dentistry
Objectives: This study aimed to evaluate the in vitro antifungal efficacy of addition of silver nanoparticles (SNPs) to Mucopren® silicone soft liner material. Materials and Methods: Twenty disc samples (8 × 2 mm) of Mucopren® silicone soft liner containing 0wt% (control), 0.5wt%, 1wt%, 2wt%, and 3wt% SNPs were fabricated. Samples were powdered and added to 150 mL of Sabouraud dextrose agar culture medium and placed on separate culture dish plates. Each plate was inoculated with 106 colony forming units per milliliter (CFUs/mL) of Candida albicans (PTCC 5027) according to the CLSI protocol, an
View details →DOI: 10.18502/fid.v18i8.6101 Negative / Null Result ReportOpen accessBusiness
Ananto Dwi Antoro, Sri Hermuningsih · 2018 · Upajiwa Dewantara: Jurnal Ekonomi, Bisnis dan Manajemen Daulat Rakyat
The purpose of this study is dividend payout ratio and BI Rate as moderation of liquidity, profitability, and leverage on financial firm value in Indonesia Stock Exchange within period 2011-2017. Research using purposive sampling method for taking sample, as many as 10 banks based on criteria. The research used secondary data from company’s annual report. The data were analyzed by using SPSS and SmastPls 3.2.7. The result showed that :1) the Liquidity and BI Rate have negative effect on company’s value but the effect were not significant, 2) profitability has a positive significant effect on f
View details →DOI: 10.26460/mmud.v2i1.3070 Negative / Null Result ReportOpen accessSports medicine
Alison Bulow, Judith E Anderson, Jeff R S Leiter et al. · 2021 · International Journal of Sports Physical Therapy
# Background Adolescent females are at much greater risk for ACL injury than their male counterparts when participating in the same sports. Preventative and pre-operative rehabilitation neuromuscular (NM) exercise programs are often recommended to improve knee function and reduce injury rates. The effectiveness of perturbation-based NM training program has been established in an adult population but has yet to be investigated in the at-risk adolescent female population. # Purpose To determine the effectiveness of a perturbation-based NM exercise program in a group of physically active adolesce
View details →DOI: 10.26603/001c.25685 Negative / Null Result ReportOpen accessGeography (General)
Fatemeh Hajari, Yaghoob Zanganeh, Alireza Hamidian · 2018 · تحقيقات جغرافيايی
Introduction and Background: The issue of identity in general and urban identity in particular has a great importance because of the role that play in recognizing individuals, objects, communities and places. In spite of the importance of this issue, urban identity crisis is alarming in recent times. Natural elements, physical and socio-cultural components are three main elements identifying that conditions and characteristics of each of them determining their role in the identity of the city. Aims: The main purpose of this study is investigate and identify the urban identity component of Sabz
Negative / Null Result ReportOpen accessSurgery
Chi Zhaocheng · 2022 · 结直肠肛门外科
[Background] The popularity of robot-assisted colorectal surgery has risen over recent years; however, patient-related advantages over laparoscopic surgery remain uncertain. [Objective] The goal of this study was to compare short-term patient outcomes following robotic and laparoscopic partial or complete rectal resections. [Design] This was a retrospective cohort study. [Settings] The study was conducted at 5 large tertiary care Kaiser Permanente medical centers across Southern California. [Patients] There were 863 consecutive robotic and laparoscopic pelvic rectal surgeries, including low an
View details →DOI: 10.19668/j.cnki.issn1674-0491.2022.02.019 Negative / Null Result ReportOpen accessMedicine (General)
Chiou-Lian Lai, Ching-Kuan Liu, Ruey-Tay Lin et al. · 2007 · Kaohsiung Journal of Medical Sciences
The aim of this study was to clarify whether the apolipoprotein E gene (APOE) is related to ischemic stroke subtypes in Taiwan's Chinese population. Using the classification of Cerebrovascular Diseases III, 143 patients with lacunar infarction, 114 patients with atherothrombotic infarction, and 112 healthy controls were enrolled. APOE genotype was determined using polymerase chain reaction. Regarding the distribution of APOE genotypes, the frequency of ϵ3/ϵ4 genotypes in lacunar patients was significantly different from that in control subjects, by logistic regression, using ϵ3/ϵ3 as a referen
View details →DOI: 10.1016/s1607-551x(08)70006-8 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Daegwang Yoo, Minsun Kang, Jaehun Jung · 2023 · Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Postpancreatectomy diabetes can be caused by resection of functioning pancreatic tissue and is associated with postoperative pancreatic islet cell mass loss and subsequent endocrine dysfunction. Diabetes is a well‐known risk factor for ischemic heart disease. However, no previous studies have investigated ischemic heart disease in patients with postpancreatectomy diabetes and pancreatic cancer. Methods and Results Rates of patients with diabetes diagnosed with pancreatic cancer who underwent pancreatectomy between 2002 and 2019 in South Korea were obtained from the Korean National H
View details →DOI: 10.1161/jaha.123.031321 Negative / Null Result ReportOpen accessMedicine
Jeremy Chung Bo Chiang, David Goldstein, Azadeh Tavakoli et al. · 2021 · Scientific Reports
Abstract Immune cell infiltration has been implicated in neurotoxic chemotherapy for cancer treatment. However, our understanding of immune processes is still incomplete and current methods of observing immune cells are time consuming or invasive. Corneal dendritic cells are potent antigen-presenting cells and can be imaged with in-vivo corneal confocal microscopy. Corneal dendritic cell densities and nerve parameters in patients treated with neurotoxic chemotherapy were investigated. Patients treated for cancer with oxaliplatin (n = 39) or paclitaxel (n = 48), 3 to 24 months prior to assessme
View details →DOI: 10.1038/s41598-021-02439-0 Negative / Null Result ReportOpen accessMaterials of engineering and construction. Mechanics of materials
Lihui ZHANG, Shuo XIE, Mingfa LUO et al. · 2024 · Jin'gangshi yu moliao moju gongcheng
Objectives: Bone tissue grinding is one of the common and basic applications in orthopedic surgery clinics. The grinding process is energy-intensive and generates a lot of grinding heat. The accumulation of this heat may cause thermal damage to biological tissues. This paper presents experimental research to investigate the bone-grinding heat and the cooling method. Methods: The combined influence of nozzle position and feed direction on the cooling effect of bone grinding under cryogenic spray cooling conditions is experimentally investigated. A bone grinding platform with three-dimensional m
View details →DOI: 10.13394/j.cnki.jgszz.2023.0238 Negative / Null Result ReportOpen accessMedicine
Darpan I. Patel, Kira Abuchowski, Bilal Sheikh et al. · 2019 · European Journal of Translational Myology
The purpose of this study was to examine the effects of exercise in modulating biomarkers of sarcopenia in a treatment naïve transgenic adenocardinoma of the mouse prostate (TRAMP) model. Thirty TRAMP mice were randomized to either exercise (voluntary wheel running) or no-treatment control group for a period of 20 weeks. During necropsy, gastrocnemius muscles and prostate tumors were harvested and weighed. Gastrocnemius concentrations of myostatin, insulin-like growth factor (IGF)-1 and tumor necrosis factor (TNF)-α were quantified. Exercise mice had greater muscle mass than controls (p=0.04).
View details →DOI: 10.4081/ejtm.2019.8520 Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Ju Chen, Faming Zhao, Faming Zhao et al. · 2023 · Frontiers in Pharmacology
Background and Purpose: The aim of this study was to explore the effect of half a year of evolocumab plus moderate-intensity statin treatment on carotid intraplaque neovascularization (IPN) and blood lipid levels.Methods: A total of 31 patients with 33 carotid plaques who received evolocumab plus statin treatment were included. Blood lipid levels, B-mode ultrasound and contrast-enhanced ultrasonography (CEUS) at baseline and after half a year of evolocumab plus statin therapy were collected. The area under the curve (AUC) reflected the total amount of acoustic developer entering the plaque or
View details →DOI: 10.3389/fphar.2022.999224 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Rafigheh Ghiasi, Mustafa Mohammadi, Javad Ashrafi Helan et al. · 2015 · Journal of Cardiovascular and Thoracic Research
Introduction: The previous studies have suggested that alteration in oxidative stress and antioxidant defense depends on various factors, such as mode, intensity, frequency and duration of exercise. In this study, we compared the effects of two various durations of resistance exercise (1 month and 4 month) on oxidative stress and antioxidant status in cardiac tissue. Methods: Thirty Wistar male rats divided into 3 groups: control (sedentary), exercise-1 (regular exercise for 1 month) and exercise-2 group (regular exercise for 4 months). After the final to the experiment, the rats were anesthet
View details →DOI: 10.15171/jcvtr.2015.32 Negative / Null Result ReportOpen accessDentistry
Mirian de Waele Souchois Marsillac, Alberto Carlos Botazzo Delbem, Ricardo de Sousa Vieira · 2016 · Brazilian Journal of Oral Sciences
A cross-sectional microhardness (CSMH) test was carried out in human dental enamel exposed to a demineralizing solution in order to evaluate two different times of indentation in sound tissue and artificially induced caries. Twenty caries-free extracted human molars had one of their smooth surfaces sectioned and the enamel surface was isolated with nail polish except for an area of 6 mm2 . These specimens were submitted to artificially induced enamel caries on a lactate buffer containing 0.1 ppm fluoride (F) during 28 days. All specimens were bisected to create groups A and B in which CSMH tes
View details →DOI: 10.20396/bjos.v7i24.8643022 Negative / Null Result ReportOpen accessMedicine
Jingjing Zhou, Shanshan Wu, Xiaojing Wu et al. · 2023 · PLoS ONE
The cultural landscape in traditional settlements is an important historical and cultural resource created by human beings in the process of historical evolution, and is an important resource for the development of traditional settlement tourism. This paper selected 21 representative traditional settlements for research using online comments from tourists as data and content analytical methods including high-frequency vocabulary, semantic networks and emotional attitudes to explore the public perspective on the connotations of cultural landscape features in traditional settlements. There are f
Negative / Null Result ReportOpen accessDentistry
M. A. Adedigba, O. O. Ojo, E. O. Ogunbodede et al. · 2008 · Nigerian Dental Journal
Objective: To determine the coping ability of people living with HIV/AIDS (PLWHA) across demographic variations of gender, duration of living with HIV infection, marital status and living arrangements either with the family or alone. Method: The research design adopted in this study was descriptive survey. The population consisted of all PLWHA in Nigeria. The sample comprised of 117 PLWHA attending clinic regularly at General Hospital Ilesa, Osun State, Nigeria. The subjects had all been exposed to voluntary counselling and testing (VCT). Only those who consented participated in the study. A s
View details →DOI: 10.61172/ndj.v16i1.179 Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Minou Kalantari, Madineh Hassani, Kazem Hassani et al. · 2013 · Journal of Rehabilitation
Objective: One of the most prevalent sensory problems in cerebral palsy is Astereognosis which has special importance in daily manual functions. The purpose of this study was to determine the level of hand stereognosis using common objects and geometric shapes in children with spastic hemiplegia and diplegia. Materials & Methods: In this cross sectional study, 20 children with cerebral palsy between 3-6 years old (9 males, 11 females) with mean age (hemiplegya: 55months, diplegya: 57months) were selected through nonrandomized convinience sampling referd to Occupational Therapy centers of Shahi
Negative / Null Result ReportOpen accessDentistry
Euis Reni Yuslianti, Anindya Sekar Ayu Ningrum, Hartanto Endrowahyudi · 2023 · Padjadjaran Journal of Dentistry
ABSTRACT Introduction: The accumulation of dental plaque is a common cause of dental and oral health problems such as caries and periodontitis, therefore it is necessary to control plaque. Brushing is the most effective way to control plaque. Currently, there are various toothpastes used by the people, one of which is herbal toothpaste. One of the herbal toothpastes that has an antibacterial potential is rambutan honey toothpaste. The purpose of this study was to analyze the effectiveness of rambutan honey toothpaste in reducing the dental plaque index. Methods: this research was Quasi Experim
View details →DOI: 10.24198/pjd.vol35no3.50310 Negative / Null Result ReportOpen accessGynecology and obstetrics
Lilian de Sá Paz Ramos, Jorge Villanova Biazús · 2024 · Revista Brasileira de Ginecologia e Obstetrícia
Abstract Objective: The purpose of this study was to compare postoperative pain between SF flap and serratus anterior muscle (SM) in direct-to-implant breast reconstruction. Methods: This is a prospective cohort study that included 53 women diagnosed with breast cancer who underwent mastectomy and one-stage implant-based breast reconstruction from January 2020 to March 2021. Twenty-nine patients (54.7%) had SF elevation, and 24 patients (45.3%) underwent SM elevation. We evaluated patient-reported early postoperative pain on the first day after surgery. Also, it was reported that all surgical
View details →DOI: 10.61622/rbgo/2024ao13 Negative / Null Result ReportOpen accessSpecial aspects of education
Nasrin Shokrpour, Shima Sheidaie, Mehdi Amirkhani et al. · 2021 · Journal of Education and Health Promotion
BACKGROUND: Given the relationship between positivity interventions and psychological problems, this study aimed to investigate the effect of positive thinking training on stress, anxiety, depression, and quality of life of hemodialysis patients. MATERIALS AND METHODS: This is a quasi-experimental and interventional study conducted on 70 hemodialysis patients referred to Fasa hemodialysis centers, Iran, between April 2019 and October 2019. Patients were selected using a simple sampling method and randomly divided into control (n = 35) and intervention (n = 35) groups. The intervention group wa
View details →DOI: 10.4103/jehp.jehp_1120_20 Negative / Null Result ReportOpen accessMedicine
Negar Sheikhdavoodi, Maryam Gheraati, Sima Hashemipour et al. · 2022 · The Journal of Qazvin University of Medical Sciences
Background: Electrolyte disorders, particularly hyponatremia, have been reported in a considerable number of patients with Coronavirus Disease 2019 (COVID-19). Objective: The current study aims to evaluate the risk factors, symptoms, and prognosis of hyponatremia in hospitalized patients with COVID-19. Methods: In this retrospective cohort study, 467 patients with COVID-19 were divided into 4 groups based on the sodium level at the time of admission: normal, mild hyponatremia, moderate hyponatremia, and severe hyponatremia. Symptoms, laboratory findings, and prognosis were compared among these
View details →DOI: 10.32598/jqums.25.3.2 Negative / Null Result ReportOpen accessSurgery
Juliana Mika Kato, Fabricio Lopes da Fonseca, Suzana Matayoshi · Revista do Colégio Brasileiro de Cirurgiões
Objective: to analyze the epidemiology, clinical features and survival rate of patients undergoing orbital exenteration (OE) in a tertiary referral hospital. Methods : we conducted a retrospective study of all patients undergoing OE at the Hospital das Clínicas, FMUSP between January 2007 and December 2012. We collected data records related to gender, age, origin, length of stay, duration of the disease, other treatments related to the disease, number of procedures outside of the face related to the disease, follow-up and histological diagnosis. Results : we treated 37 patients in the study pe
View details →DOI: 10.1590/0100-69912016001009 Negative / Null Result ReportOpen accessSpecial aspects of education
Ima Fitriyah, Fitriatul Masitoh, Utami Widiati · 2022 · Indonesian Journal of Applied Linguistics
Classroom-based language assessment (CBLA) in the Indonesian context has become more significant since the shift of the assessment model from summative based assessment (Ujian Nasional or the final exam) to formative-based assessment (Asesmen Kompetensi Minimum (AKM); therefore, teachers need to develop their classroom-based language assessment literacy (CBLAL). The model places a greater emphasis on students' learning outcomes in class rather than final test scores. This study aims to examine the CBLAL level of experienced and novice EFL teachers, their perceptions of CBLAL, and their needs f
View details →DOI: 10.17509/ijal.v12i1.46539 Negative / Null Result ReportOpen accessMedicine
Azam Ardeh, Elham Goodarzi, Zahra Madadi et al. · 2025 · BMC Research Notes
Abstract Background Marital relationships, like any other interpersonal bond, encompass both positive and negative dimensions. Central to the success of marriage is the level of satisfaction and commitment experienced by the partners. This study aims to compare the efficacy of cognitive-behavioral couple therapy and schema-based couple therapy in reducing the desire for divorce and marital boredom. Methods This experimental study employed a pre-test-post-test design with a control group. The research sample comprised couples experiencing marital issues who sought counseling at various counseli
View details →DOI: 10.1186/s13104-025-07339-4 Negative / Null Result ReportOpen accessMedical emergencies. Critical care. Intensive care. First aid
Anoush AZARFAR, Yalda RAVANSHAD, Aghillolah KEYKHOSRAVI et al. · 2014 · Turkish Journal of Emergency Medicine
SUMMARY: Objectives: The objective of this study is to evaluate the effect of rapid intravenous rehydration to resolve vomiting in children with acute gastroenteritis. Methods: This randomized control trial was conducted in the pediatric emergency department in a tertiary care center in Tabriz, North-West of Iran. The study participants' were 150 children with acute gastroenteritis and vomiting who were moderately dehydrated, had not responded to oral rehydration therapy and without any electrolyte abnormalities. 20–30 cc/kg of a crystalloid solution was given intravenously over 2 hours and th
View details →DOI: 10.5505/1304.7361.2014.66049 Negative / Null Result ReportOpen accessSurgery
Rajeev Kumar, Anita Malik, Monika Kohli et al. · 2013 · Archives of Clinical and Experimental Surgery
Background: Intracranial endoscopy is a minimum invasive procedure, which reduces trauma to the brain, is cost-effective, and carries a shortened hospital stay with an improved postoperative outcome. Objective: To monitor intracranial pressure changes during intracranial endoscopy among children and adults under general anesthesia/sedation, and to compare the intracranial pressure changes between children and adults receiving general anesthesia and among adults receiving general anesthesia and sedation. Methods: The present cross-sectional study was conducted in one of the tertiary care hospit
View details →DOI: 10.5455/aces.20130118041840 Negative / Null Result ReportOpen accessMedicine
Dandan Chen, Huamin Wu, Feifeng Huang et al. · 2025 · PLoS ONE
Objective This study explored the prognosis of high-grade squamous intraepithelial lesion (HSIL) patients with negative margins, investigating the impact of different distances between lesions and incisal margins in conization specimens. Methods This retrospective cohort study included 240 HSIL patients. Patients with negative incisal margins were divided into 3 groups according to the distance between the lesion and the incisal margin in the conization tissue. Group 1 consisted of a distance of 3 mm (n = 202). For patients with lesions close to the incisal margin (≤3 cm), the decision between
View details →DOI: 10.1371/journal.pone.0331184 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Alexandre Pereira Tognon, Murilo Foppa, Vivian Cristine Luft et al. · 2015 · Arquivos Brasileiros de Cardiologia
Background: Echocardiography, though non-invasive and having relatively low-cost, presents issues of variability which can limit its use in epidemiological studies. Objective: To evaluate left ventricular mass reproducibility when assessed at acquisition (online) compared to when assessed at a reading center after electronic transmission (offline) and also when assessed by different readers at the reading center. Methods: Echocardiographers from the 6 ELSA-Brasil study investigation centers measured the left ventricular mass online during the acquisition from 124 studies before transmitting to
View details →DOI: 10.5935/abc.20140183 Negative / Null Result ReportOpen accessSurgery
Tetsuya Tachibana, Hiroki Katagiri, Hideyuki Koga et al. · 2023 · Journal of Joint Surgery and Research
Purpose: The advantage of total hip arthroplasty (THA) in an anterior approach compared with a posterior approach in terms of early postoperative pain and function and lowering dislocation risks is controversial. This study aimed to identify whether THA using the anterior approach lowers costs compared with the posterior approach. Methods: We identified 294 patients who underwent primary THA and compared the cost of total inpatient stay, inpatient length of stay (LOS), cost of operating room, and the rates of discharged patients, complications, and reoperation between the anterior and posterio
View details →DOI: 10.1016/j.jjoisr.2023.10.001 Negative / Null Result ReportOpen accessMedicine
Van de Vyver A, Taylan O, Peersman G et al. · 2026 · Archives of orthopaedic and trauma surgery
Objectives This study aimed to analyze to what extent a novel intraoperative navigation platform (Next-AR, Medacta) for total knee arthroplasty (TKA) allows to restore the native knee joint kinematics and strains in the medial collateral…
View details →DOI: 10.1007/s00402-026-06267-7 