A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21309 results · page 377 of 711
Famuyide L, Patel J, Nembhard WN · 2026 · Birth defects research
Background Hypospadias is one of the most common genital defects in boys, affecting about 1 in 125 live-born boys. Several studies have examined the association between a single environmental exposure and risk of hypospadias, but few have…
Ye B, Liu Y, Zhang J et al. · 2026 · Frontiers in nutrition
Background To investigate the associations between consumption of sugar-sweetened beverages (SSBs), artificially sweetened beverages (ASBs), and natural juices (NJs) and incident kidney stone disease (KSD), and to assess whether genetic…
Kılıç A, Koçak Ulucaköy R, Osmanov Z et al. · 2026 · Biomarkers in medicine
Objective Biomarkers that accurately reflect disease activity and inflammatory burden are needed, particularly in the early stages of spondyloarthropathy (SpA). This study aimed to evaluate the association between serum neopterin levels…
Sussadee M, Jarudecha T, Muikaew R et al. · 2026 · Animals : an open access journal from MDPI
Feline hypertrophic cardiomyopathy (HCM) is the most common cardiac disease in cats, causing morbidity and mortality. Recently, a variant in the Alström syndrome protein 1 ( ALMS1 ) gene has been reported to be associated with HCM in…
Choi SJ · 2026 · BMC public health
Background Walking is a widely accessible form of physical activity and has been consistently associated with improved health-related quality of life (HRQoL) at the individual level. However, less is known about how walking participation…
McCaw K, Fink B, Danis D et al. · 2026 · American journal of veterinary research
Objective To compare the accuracy of a tibial plateau-leveling osteotomy (TPLO) using a modular guide (OssAbility) compared to the traditional freehand method. We hypothesized that guide use would improve TPLO centering and accuracy in the…
Gaba K, Kumar K, Kaushik R et al. · 2026 · Cureus
Background The use of post-mortem blood culture as a diagnostic tool in medico-legal autopsies is limited. Differentiating true infection from contamination or post-mortem bacterial translocation remains a challenge. This study aimed to…
Zehra J, Kumari C, Bibi A et al. · 2026 · Preprint
Abstract Objective This study aimed to investigate in-hospital mortality rates among different Mannheim Peritonitis Index (MPI) score groups in patients who underwent emergency laparotomy due to hollow viscus perforation. Methods We…
Chaudhry A, Moin M, Malik TG et al. · 2026 · JPMA. The Journal of the Pakistan Medical Association
To determine the shape and size of foveal avascular zone in terms of perimeter, circularity, roundness and axial ratio using optical coherence tomography angiography. The retrospective study was conducted at the Yaqeen Vison Clinic,…
He L, Wang K · 2026 · Medicine
Total bilirubin possesses antioxidant and immunomodulatory properties, and its role in childhood asthma is a topic of ongoing debate. We employed both a cross-sectional study and Mendelian randomization (MR) analysis to explore the link…
Wei W, Shaibi GQ, Temkit H et al. · 2026 · Journal of pediatric hematology/oncology
Introduction Alkylators are gonadotoxic in a cumulative manner, with overall exposure quantified as the cyclophosphamide equivalent dose (CED). Inhibin B is used as a surrogate marker of fertility in adult male childhood cancer survivors…
Barghash M, Obayi E, Itaman U et al. · 2025 · Cureus
Background Hiatal hernia is commonly associated with gastro-oesophageal reflux disease (GORD). However, the relationship between hernia size and reflux severity remains unclear. This study aimed to assess the impact of the hiatal hernia…
Md Kasim NA, Shirinal Izuan US, Karuppannan M · 2026 · BMC health services research
BACKGROUND: Healthcare providers commonly recommend medication reminders as a strategy to enhance adherence to prescribed medications. Patient demographic characteristics may influence medication adherence and incorporating patient-centred…
Prates AJ, Curioni OA, Ramos DM et al. · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives: Laryngeal cancer has a high incidence and mortality rate, especially in advanced stages. Stoma recurrence after total laryngectomy is rare but lethal, and its risk factors remain controversial. We aimed to assess…
Voigt MB, Böhner A, Bahaaeldin M et al. · 2026 · CVIR endovascular
To evaluate the occurrence of periaortic inflammation, including abscess formation, as a complication following endoleak repair after endovascular aortic repair. This retrospective single-center study analyzed 88 EVAR revisions for…
Zhao N, Zhan Y, Choi J et al. · 2026 · The Journal of nutrition
Background The consumption of live microbes beyond probiotics is associated with health benefits. Despite growing interest in live microbe intake, comprehensive data on its dietary sources and research on their potential health effects in…
Mostafavi M, Rezazadeh F, Fattahi MJ et al. · 2026 · Journal of dentistry (Shiraz, Iran)
Background Multiple studies have revealed an association between vitamin D levels, genetic polymorphisms of the VDR (vitamin D receptor) gene, and the underlying causes of various bone and cartilage disorders. Purpose This study aimed to…
Ozaki K, Nishioka Y, Kamitani F et al. · 2026 · Diabetes research and clinical practice
It has been controversial whether COVID-19 increases the risk of new-onset type 1 diabetes mellitus. Using large-scale claims data, we found no statistically significant association between COVID-19 and incident type 1 diabetes mellitus in…
Buran A, Altaş H, Özkaya Uçar Y et al. · 2026 · Journal of the Turkish German Gynecological Association
Objective To evaluate pathological findings in patients positive for human papillomavirus (HPV)-31. Material and methods This retrospective study included patients evaluated in a tertiary colposcopy clinic. The 3,546 patients tested for…
Braun S, Selkridge I, Nocon A et al. · 2026 · Arthroplasty (London, England)
Background Extensor mechanism disruption following total knee arthroplasty (TKA) significantly impairs knee function and quality of life. Extensor mechanism reconstruction (EMR) is effective but carries risks, including post-operative…
Sarpeleh F, Ehtesham N, Mirjani R et al. · 2026 · Lupus
ObjectiveThe dysfunction of interleukin-7 receptor alpha (IL-7Rα), which is encoded by the IL7RA gene, has been implicated in the development of systemic lupus erythematosus (SLE). This study aimed to investigate the relationship between…
Mazurek A, Jankowski M, Grudziąż-Sękowska J · 2026 · BMC nephrology
BACKGROUND: The weekend effect refers to the observation that patients admitted to the hospital on the weekend experience poorer clinical outcomes than patients admitted during the workweek. This effect has not been previously studied…
Chen JSC, Osborne JWA, Menz HB et al. · 2026 · Journal of foot and ankle research
Background Fatty infiltration, or fatty atrophy, of the abductor digiti minimi (ADM) muscle of the foot is proposed to be associated with entrapment of the first branch of the lateral plantar nerve (i.e., Baxter's neuropathy) as part of…
Millán J, Gal B, Esquerda M et al. · 2026 · BMC medical education
Background In Spain, access to specialized medical training is determined through a highly competitive national examination (MIR). While the educational climate of medical schools has been associated with students' learning outcomes and…
Zhong R, Chen S, Cui N et al. · 2026 · Preprint
Abstract Background: Adolescents diagnosed with depression frequently experience anxiety and other psychological symptoms. Yet, the interrelationships among multiple psychological symptoms are under-investigated. Network analysis is a…
Mahaboob L, Chehade H, Gnanamuthu SS et al. · 2026 · Preprint
Abstract Background Fast-food consumption has become increasingly prevalent among university students, contributing to unhealthy dietary patterns and rising obesity rates. Understanding students' fast-food consumption habits, knowledge,…
Vejdani-Jahromi M, Calle E, Ganem O et al. · 2026 · AJNR. American journal of neuroradiology
Background and purpose Alzheimer disease (AD) is a progressive neurodegenerative disorder that predominantly affects the aging population. Anti-amyloid β (anti-Aβ) therapies, such as lecanemab, have been developed to slow disease…
Brown J, Abdullah N, Sobuwa S · 2026 · International journal of emergency medicine
BACKGROUND: Endotracheal intubation is a critical life-saving intervention in prehospital emergency care, yet evidence supporting its safe implementation by prehospital practitioners in lower- to middle-income countries remains limited.…
Lukies M, Darby O, Wani S et al. · 2026 · Journal of medical imaging and radiation oncology
Uterine artery embolisation (UAE) is an evidence-based treatment for symptomatic fibroids and adenomyosis. Ultrasound is commonly utilised for assessment post UAE given its wide availability and low cost; however, contemporary studies…
Karatutlu AS, Karatutlu MA, Aydin S · 2026 · Renal failure
Chronic kidney disease (CKD) is characterized by progressive renal fibrosis and irreversible loss of kidney function. Decorin, an extracellular matrix proteoglycan with antifibrotic properties, may reflect underlying fibrotic activity and…