A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21720 results · page 376 of 724
Rue I, Jones S, Soltaninejad M et al. · 2025 · Preprint
Abstract Serum neurofilament light (sNfL) is a biomarker of axonal integrity which is elevated in neurodegenerative diseases. Although common psychiatric disorders are not neurodegenerative, some studies have found slightly higher levels…
Agarwal R · 2026 · American journal of hypertension
Background The mechanism of hypertension associated with erythropoiesis-stimulating agents in chronic kidney disease (CKD) is complex and remains poorly understood. Methods Here, anemic hypertensive patients with CKD and well-controlled or…
Tamburro MK, Carlson JA, Yen WK et al. · 2026 · Matrix biology : journal of the International Society for Matrix Biology
Tendon injuries account for considerable and escalating clinical burden. After injury, tendons heal poorly with persistent fibrovascular scar. Unlike healthy tendon which is type I collagen (COL1)-rich and highly-aligned, fibrovascular…
Lisco A, Borgognone A, Vanpouille C et al. · 2026 · The Journal of infectious diseases
Background The cervicovaginal microbiome may affect HIV-1 susceptibility and can in turn influence the prevalence and clinical course of HIV-1 and other sexually transmitted diseases. As the determinants, immunological correlates and…
Yin TK, Sengar N, Fang TY et al. · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
PURPOSE: Fluctuating hearing loss in Ménière’s disease (MD) presents a key clinical challenge due to lack of reliable prognostic markers. The clinical value of transient-evoked otoacoustic emissions (TEOAEs) low-frequency components…
Gkirgkiris K, Charalampaki E, Margioula E et al. · 2026 · Anaesthesia, critical care & pain medicine
Background stive heart failure may coexist and aggravate the non-cardiogenic pulmonary edema of acute respiratory distress syndrome (ARDS). Yet, patients with congestive heart failure are likely under-represented in ARDS trials. We aimed…
Bhattarai S, Baral S, Bhowmick M et al. · 2026 · Preprint
Abstract Objective: Malnutrition is a common complication of acute pancreatitis (AP), and it may adversely affect outcomes. This study aimed to evaluate short-term changes in body composition and the development of sarcopenia in patients…
Holian JA, Bolton MD, Wilson DI · 2025 · Current Research in Food Science
Addition of small amounts of glycerol to milk chocolate during the tempering stage can yield a product which exhibits enhanced mechanical strength and retards motion of the continuous phase (cocoa butter, a mixture of fats) of this dense…
Serttas MF, Kochai A, Eryilmaz BH et al. · 2025 · Medicine
Background This study compares the change in cervical sagittal alignment (CSA) after surgery in Lenke 5 patients who underwent selective and nonselective fusion and to evaluate the effect of this situation on functional results. Methods A…
Murphy L, Mingoia R, Bianchi E et al. · 2026 · Regulatory toxicology and pharmacology : RTP
Regulatory testing for agrochemicals has traditionally included a 90-day toxicity study in a non-rodent species, usually the dog. With growing emphasis on the 3Rs-replacement, reduction, and refinement of animal use-and increased adoption…
Lutz D, van den Berg C, Neill MG et al. · 2026 · Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
Objectives To investigate time spent completing neuromuscular training (NMT) exercises in youth soccer team warm-up across a season considering sex, level of play, session type, and coach exposure and awareness of NMT. Design…
Ma J, Yang M, Wang B et al. · 2026 · Biomacromolecules
Peptide-protected gold nanoclusters (P-AuNCs) were ideal candidates for constructing antibacterial agents. However, the individual P-AuNCs could only exert limited target behavior and antibacterial efficiency. Herein, CA 2 R 5 /GSH-AuNCs…
Endendijk JJ · 2025 · Psychological reports
Interventions in which people are exposed to counter-stereotypical role models are often used for breaking gender stereotypes. Most gender role-model interventions focus on adolescents and emerging adults. Yet, middle childhood might be a…
Gilford E, Johnstone M, Pitt M et al. · 2026 · Preprint
Pesticide exposure has been proposed as a major driver of global insect declines. Sublethal effects occur when non-fatal pesticide exposure disrupts behaviour or physiology in ways that may reduce survival or reproductive success. However,…
Pathak BK, Maurya M, Mishra N et al. · 2026 · Clinical pediatrics
Microcytic hypochromic anemia is common in severe acute malnutrition (SAM) children, but macrocytic anemia (vitamin B12/folate deficiency) is not uncommon. Vitamin B12 deficiency leads to anemia and developmental slowing. We looked for the…
Polman EMN, Rijsdijk KF, Cornelissen P et al. · 2026 · Ecosystems.
Water table management such as temporal flooding is an important strategy for influencing vegetation development and creating suitable habitat for wildlife in managed wetland systems. Water table fluctuations can also affect soil carbon…
Bodegom ME, Hissink RJ, El Moumni M et al. · 2026 · Annals of vascular surgery
Background Carotid stenosis is traditionally considered a relatively stable condition between symptom onset and carotid endarterectomy. However, short-term changes in duplex-derived hemodynamic parameters may occur during the waiting…
Li J, Wang Q, Xie N et al. · 2026 · Cognitive processing
In order to better adapt to spatial environments, individuals often establish a spatial frame of reference system to represent objects and their positions within a scene. This study utilized a partial scene recognition paradigm across…
Murphy E, Poudel G, Dakhili AH et al. · 2026 · Addictive behaviors
Introduction Cannabis Use Disorder (CUD) can come with intense cravings, which can trigger compulsive use/relapse, underscored by anterior cingulate cortex (ACC) hyperactivity during cannabis cue-reactivity functional neuroimaging (fMRI)…
Kim YJ, Kim C, Park J et al. · 2026 · Nutrients
Background/Objectives: This study examined the association between dietary acid load (DAL) and metabolic syndrome (MetS)-related parameters in Korean adults undergoing eating habit modification. Methods: Forty-eight Korean adults (≥19…
Lev-Ari L, Mintz Malchi K, Ludmir E et al. · 2026 · Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)
Background Childhood sexual abuse (CSA) is associated with significant psychiatric morbidity and has been reported at notable rates among Jewish Israeli women. Yet data regarding abuse characteristics, psychiatric history and longitudinal…
Reil JC, Sequeira V, Coppée C et al. · 2026 · Circulation. Heart failure
Background Obstructive hypertrophic cardiomyopathy (oHCM) is characterized by left ventricular (LV) outflow tract obstruction, which increases afterload and chronically activates the Anrep response, a compensatory (afterload-driven) state…
Leon D, Maslivec A, Guest B et al. · 2026 · Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Ceramic-on-ceramic hip resurfacing arthroplasty (CoC-HRA) has been developed to eliminate metal ion concerns which have been associated with metal-on-metal hip resurfacing arthroplasty (MoM-HRA) while maintaining similar functionality. The…
Brayner B, Mason S, Karimi E et al. · 2026 · American journal of physiology. Endocrinology and metabolism
Subcutaneous adipose tissue microvascular blood flow (MBF) increases in response to insulin or a meal, with gastric inhibitory polypeptide (GIP) being a proposed mechanism. This vascular response is blunted in people with insulin…
Zampino S, Hosler R, Brown K et al. · 2026 · The Journal of cardiovascular nursing
Background Reiki plus manual therapy are utilized to improve relaxation, sleep, emotional state, and pain. Evidence within hospital settings was limited, and previous studies had weak designs. Objective The purpose of this study was to…
Rudokas V, Koliada M, Stankevic V et al. · 2026 · Sensors (Basel, Switzerland)
Magnetic sensors based on the colossal magnetoresistance (CMR) effect in manganite thin films are promising for high-field measurements due to their wide operating range, low magnetoresistance anisotropy, and ability to function without…
Randall MM, Uchimura RN, Steinmann JC et al. · 2026 · Injury
Introduction Vertebral compression fractures are common and incur significant healthcare costs. Orthotic bracing is a frequently used treatment; however, studies have shown uncertainty regarding its effectiveness. Upright radiographs after…
Siddiqui TG, Simonsen THB, Lie Selle M et al. · 2026 · Scandinavian journal of primary health care
Background Z-hypnotics are commonly prescribed for insomnia, but their use in older adults is associated with an increased risk of adverse events. Aim We examined the long-term effect of brief intervention (BI) for inappropriate z-hypnotic…
Hussain A, Shah TH, Bashir S et al. · 2026 · ERJ open research
Respiratory muscle training can be used in conjunction with CPAP or in situations precluding use of CPAP therapy. It should be used as a complimentary measure rather than an alternative to CPAP. https://bit.ly/3JqDDU7.
van der Horst DEM, van Uden-Kraan CF, Stiggelbout AM et al. · 2026 · Patient education and counseling
Objective Effective patient-clinician communication is essential in chronic kidney disease (CKD) to support treatment adherence and slow down disease progression. In this proof-of-concept study we evaluated the effects of a CKD dashboard,…