A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21294 results · page 328 of 710
Ruiz-Palacios GM, Cahn PE, Halperin SA et al. · 2026 · Vaccine
Background There is a concern about the potential increased risk of acquiring HIV infection after vaccination with adenovirus type 5 (Ad5) vector-based vaccines. We aimed to investigate whether Ad5-nCoV increases the risk of HIV infection.…
Al-Mansor AN, Alhamd AD, Al-Musawi FM · 2025 · Preprint
Abstract Date palms (Phoenix dactylifera L.) struggle in arid places due to water scarcity and rising demand. Therefore, we must find more efficient ways to water them to maintain economically viable water use. Researchers in the southern…
Li RQ, Su S, Zhan LP et al. · 2026 · Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
Objective: To investigate the differences in the changes of periodontal ligament area (PDLA) and related clinical indicators before and after maxillary central incisor movement under different orthodontic treatment regimens. Methods: This…
Zhang XR, Yang GJ, Jiang LC et al. · 2026 · The New phytologist
Nitrogen (N) inputs generally benefit grassland biomass production. Supporting evidence, however, comes mainly from experiments with high N input rates and from grasslands without utilization. Using a 10-yr field experiment in temperate…
Liang XS, Ning Y, Wang HY et al. · 2026 · The New phytologist
Nitrogen (N) enrichment is expected to exacerbate plant phosphorus (P) limitation, yet this assumption has seldom been empirically tested. We investigated the effects of 7-9 yr of N and P addition on grassland aboveground net primary…
Schaefer N, Kelaher BP, Bishop MJ · 2026 · Marine environmental research
Climate warming is exposing intertidal species to increasing temperatures, threatening the survival of those already experiencing conditions close to their upper thermal limit. On intertidal rocky shores, habitat-forming seaweeds can…
Dupla X, Bertagni MB, Grand S · 2025 · Environmental science & technology
Enhanced rock weathering (ERW) is a CO 2 removal technology that involves spreading finely ground silicate rock on fields. The chemical weathering of this rock powder removes atmospheric CO 2 in the form of bicarbonate ions and secondary…
Hernigou P, Caton J · 2025 · International orthopaedics
Purpose Calcium pyrophosphate dihydrate (CPPD) deposition, often visible radiographically as chondrocalcinosis, frequently accompanies knee osteoarthritis and is usually encountered at the time of arthroplasty. Whether its presence…
Klaassen AD, Willigenburg NW, Musters JWQ et al. · 2026 · The Journal of bone and joint surgery. American volume
Background Hip dislocation is the most common reason for early revision after total hip arthroplasty (THA). To prevent dislocation, patients are often prescribed movement restrictions following THA; however, these restrictions can be…
Xie Z, Yang C, Yin Y et al. · 2025 · Heart (British Cardiac Society)
Background Intensive blood pressure (BP) control Methods This is a post hoc analysis of the China Rural Hypertension Control Project. Mixed-effect Cox proportional regression and generalised estimating equation models were used to…
Boito L, Rijnders J, Steinwidder L et al. · 2025 · Preprint
Abstract Enhanced weathering (EW) of silicate minerals has emerged as a promising carbon dioxide removal (CDR) strategy, with potential benefits for soil fertility and crop performance. However, the soil processes that determine these…
Chandan Reddy S, Mao T, Gendreau J et al. · 2026 · Clinical neurology and neurosurgery
Objective Oligodendrogliomas are typically benign tumors that arise within the white matter tracts of the cerebral hemispheres. Surgical resection, radiotherapy (RT), and chemotherapy (CT) are utilized to prolong survival in patients…
Davila-Piñón P, Díez-Martín AI, Nogueira-Rodríguez A et al. · 2026 · Endoscopy
Background and study aim The impact of computer-aided detection (CADe) systems remains uncertain. We evaluated whether PolyDeep, a CADe system, improves adenoma detection rate (ADR) in a colorectal cancer (CRC) screening program. Patients…
de Lint L, de Vries R, van Rookhuijzen M et al. · 2026 · Appetite
Food choices are not made within a vacuum but depend upon earlier decisions, resulting in spillover effects where subsequent choices are either similar (consistency) or contrasting (balancing). Little is known about spillovers in…
Pervane YD, Bağlan E · 2025 · Expert opinion on biological therapy
Objective Biologic agents have been used in colchicine-resistant familial Mediterranean fever (FMF) patients and in patients with comorbidities including juvenile idiopathic arthritis (JIA). The main aim of our study was to evaluate the…
Savin Z, Ben-David R, Shem-Tov Dlugy A et al. · 2025 · Canadian Urological Association journal = Journal de l'Association des urologues du Canada
Introduction Active surveillance (AS) requires regular monitoring to detect disease progression. Multiparametric magnetic resonance imaging (mpMRI) and targeted biopsies are commonly used to identify clinically significant prostate cancer…
Collins SF, Soliz L, Tucker G et al. · 2025 · Science of the Total Environment
Here, we assessed patterns of microplastics (MP; particles <5 mm) and microfibers (MF; fibers <5 mm) within benthic macroinvertebrates and fishes collected from a polluted urban stream (10-km segment; n = 5 reaches; 200-m reach lengths).…
Akiyama H, Sasaki Y, Tago K et al. · 2025 · Agriculture, Ecosystems and Environment.
Previous studies have reported that nitrification inhibitors are effective in reducing nitrous oxide emissions. However, no studies have reported the effectiveness of 3,4-dimethylpyrazole phosphate, and 3,4-dimethylpyrazole succinic acid…
Ackermann DM, Medcalf E, Bracken K et al. · 2026 · Journal of clinical epidemiology
Objectives Digital reminders are widely used in clinical trials, but their design is rarely evidence-based. We evaluated the effectiveness of two types of digital reminders for trial task completion. Study design and setting This…
Hadi CE, Dailaty AA, Sobh AH et al. · 2025 · Preprint
Abstract Background Postoperative pulmonary complications (PPCs) remain a major determinant of morbidity after noncardiac surgery. Whether prior SARS-CoV-2 infection independently heightens PPC risk in the contemporary, highly vaccinated,…
Jones PAT, Brockwell E, Hassan A et al. · 2025 · British journal of sports medicine
Objective Recreational and elite athletes report avoiding breastfeeding when returning to physical activity following childbirth due to a perceived increased risk of injury; yet, there are no empirical data to support this relationship. We…
Sadowska-Klasa A, Bełdzińska-Gądek K, Klein-Awerjanow K et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Cytomegalovirus (CMV) pneumonia is a serious complication in immunocompromised patients, but its role in non-transplant populations remains unclear. Methods We analyzed CMV DNA in bronchoalveolar lavage (BAL) samples from 100…
Wöhner S, Jescheniak JD · 2025 · Preprint
The production of a word is delayed by the recent production of one or more semantically related words. This phenomenon, known as semantic interference, has been observed in picture naming tasks involving either large sets of pictures…
Murray RL, Baldwin D, Brain K et al. · 2026 · Thorax
Introduction Lung cancer screening (LCS) with low-dose CT offers a teachable moment for smoking cessation (SC), but the optimal way to implement SC within LCS is unclear. The Yorkshire Enhanced Stop Smoking (YESS) study assessed the…
Garrido-Bautista J, Ortega Z, Pérez-Jiménez A et al. · 2025 · Ecological and evolutionary physiology
AbstractClutch size variation may be adaptive in bird populations if parents lay a clutch size that maximizes offspring recruitment. Brood size manipulation experiments allow for testing the optimization of clutch size by studying the…
Brown N, King SW, Bagshaw O et al. · 2026 · Injury
Introduction The Ilizarov method is an established technique for complex cases. Decisions about circular frame removal are imprecise, with no fully reliable method to confirm union. Errors can lead to complications such as refracture,…
Nie C, Zhong H, Shi H et al. · 2026 · Food chemistry
This study evaluated the effects of sodium substitutes (KCl, MgCl 2 , and CaCl 2 ) and soybean dietary fiber (SDF) on the textural, sensory, digestive, and storage properties of emulsion sausages. Replacing 25 % of NaCl with KCl or MgCl 2…
Feng Y, Liu Y, Ding X et al. · 2026 · The Journal of nutritional biochemistry
Alcohol-related liver disease is accompanied by hepatic zinc deficiency. We synthesized a zinc-glutathione (ZnGSH) complex as a zinc delivery system to test the hypothesis that effective zinc supplementation can recover the liver from…
Lee D, Lee H, Lee C et al. · 2026 · Anesthesia and analgesia
Background Drug-induced dreams during intravenous sedation vary by pharmacological agent and influence patient experiences, yet the role of preoperative positive suggestions in modulating these dreams is unclear. This study aimed to…
Niecestro R, Foster EC, Millist L et al. · 2026 · European journal of drug metabolism and pharmacokinetics
Background and objectives ES-481 is a potent and selective antagonist of the transmembrane alpha-amino-3-hydroxy-5-methyl-4 isoxazolepropionic acid (AMPA) receptor regulatory protein (TARP)-y8-dependent AMPA receptor being developed for…