Negative / Null Result ReportMedicine
Xia MH, Liu KC, Zhao W et al. · 2025 · Brachytherapy
Purpose To compare the effectiveness and safety of CT-guided iodine-125 seed brachytherapy in conjunction with chemotherapy against chemotherapy alone for the management of intermediate and advanced non-small cell lung cancer (NSCLC)…
View details →DOI: 10.1016/j.brachy.2024.09.005 Negative / Null Result Report
Joly A, Thoumas J, Lambert A et al. · 2024 · Preprint
Dysregulation of energy metabolism, including hyperglycemia, insulin resistance and fatty liver have been reported in a substantial proportion of lean children. However, non-obese murine models recapitulating these features are lacking to…
View details →DOI: 10.1101/2024.07.22.604540 Negative / Null Result ReportOpen accessMedicine
Kavoussi PK, Weiss J, Pyo J et al. · 2026 · The Journal of urology
Purpose To assess varicocele repair effect on semen parameters and improved candidacy for in vitro fertilization/intracytoplasmic sperm injection or lesser involved treatment options depending on semen parameter response following…
View details →DOI: 10.1097/ju.0000000000004944 Negative / Null Result ReportOpen accessMedicine
Strowd RE, de la Fuente M, Bauer TM et al. · 2026 · Neuro-oncology advances
Recurrent isocitrate dehydrogenase (IDH) wild-type glioblastoma has no established standard-of-care treatment. Preclinical models have demonstrated that hypoxia-inducible factor-2 alpha (HIF-2α) contributes to stabilizing the hypoxic…
View details →DOI: 10.1093/noajnl/vdaf242 Failed Experiment ReportMedicine
Yin H, Yu Y, Shen Y · 2024 · International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience
Cerebellofaciodental syndrome characterized with dysmorphic features, intellectual disability, and brain anomalies. Now its clinical spectrum expanded more manifestations including bilateral sensorineural hearing impairment and inner ear…
View details →DOI: 10.1002/jdn.10365 Failed Experiment ReportMedicine
Gerpe C, Toscano MJ · 2024 · Journal of Applied Poultry Research.
The aim of our study was to investigate the effects of two interventions (i.e., two treatments across two independent experiments, each with its own control) that were thought to reduce fractures and stress related responses (e.g., changes…
Negative / Null Result ReportOpen accessMedicine
Kaya G, Yüksel H, Taneli F et al. · 2026 · Clinical and translational science
In cat sensitized children, decision to eliminate exposure to cats depends on the clinical outcome. In this study, we aimed to examine the relationship between molecular cat allergen sensitization and exhaled breath condensate (EBC) IL-4,…
View details →DOI: 10.1111/cts.70521 Negative / Null Result ReportMedicine
Khin STMM, Jafar SM, Ju M et al. · 2025 · Journal of virological methods
Feline morbillivirus (FeMV) is a globally emerging virus that has been linked to chronic kidney disease (CKD) in infected cats. Immunological assays, such as enzyme-linked immunosorbent assay (ELISA), are important for studying the virus…
View details →DOI: 10.1016/j.jviromet.2025.115216 Negative / Null Result ReportOpen accessMedicine
Lagström RMB, Bräuner KB, Frandsen MN et al. · 2026 · Endoscopy international open
Background and study aims Because most colorectal polyps are diminutive and carry minimal cancer risk, artificial intelligence (AI) might enable diagnostic strategies such as leave-in-situ and resect-and-discard, provided it meets…
View details →DOI: 10.1055/a-2860-7702 Negative / Null Result Report
Rodgers TW, Mock KE · 2025 · Preprint
Environmental DNA (eDNA) offers a sensitive tool for detecting aquatic species, including those at low population densities. However, effective use of eDNA in conservation and monitoring efforts requires an understanding of detection…
View details →DOI: 10.1101/2025.01.06.631567 Negative / Null Result ReportMedicine
Javaugue V, Pascal V, Nasr SH et al. · 2025 · Kidney international
Introduction Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is classified within the spectrum of monoclonal gammopathy of renal significance (MGRS). However, PGNMID features an unexpected low rate of…
View details →DOI: 10.1016/j.kint.2025.07.039 Negative / Null Result ReportMedicine
Calabrese V, Metro D, Alibrandi A et al. · 2025 · Nefrologia
The Classification and Regression Tree (CART) is a supervised learning approach useful used to segment the space of and the predictors/features space into smaller homogeneous regions that are, represented in a decision tree. It computes…
View details →DOI: 10.1016/j.nefroe.2025.04.008 Negative / Null Result ReportOpen accessMedicine
Costa TH, Bonet-Bub C, Kutner JM · 2024 · Hematology, transfusion and cell therapy
Background and objectives The identification of platelet antibodies is essential for diagnosing and managing conditions such as fetal and neonatal alloimmune thrombocytopenic purpura, post-transfusion purpura, and immune platelet…
View details →DOI: 10.1016/j.htct.2024.06.004 Negative / Null Result Report
Rafiee Y, Shiramizu V, Jones BC · 2024 · Preprint
Previous research suggests that emotion recognition ability varies within and between individuals, potentially influenced by person-related factors such as levels of sex hormones. Studies have examined links between the menstrual cycle,…
View details →DOI: 10.31234/osf.io/xgze4 Negative / Null Result ReportMedicine
Epchtien RE, Temkin E, Masarwa S et al. · 2025 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
We evaluated whether skin sampling with E-swabs is an effective alternative to pre-moistened sponges for detecting carbapenem-resistant Acinetobacter baumannii (CRAB) carriage. Skin samples were collected by sponges with enrichment and…
View details →DOI: 10.1007/s10096-025-05055-2 Negative / Null Result ReportOpen accessMedicine
Cullinane A, Nelly M, Dayot L et al. · 2025 · Viruses
This study describes a comparison of the detection of rotavirus in clinical samples from foals using two commercially available rapid antigen detection (RAD) kits, with the detection of rotavirus nucleic acid via a laboratory-based,…
View details →DOI: 10.3390/v17030413 Negative / Null Result ReportOpen accessMedicine
Hellingman A, Göttle NL, Walz A et al. · 2026 · ACS infectious diseases
Malaria remains a major global health threat, and the emergence of partial artemisinin resistance challenges current treatment regimens. Reliable antimalarial screening assays are therefore essential for identifying new drug candidates.…
View details →DOI: 10.1021/acsinfecdis.5c00924 Negative / Null Result ReportOpen accessMedicine
Zhang C, Li J, Zhuang W · 2026 · Frontiers in oncology
Background Acute myeloid leukemia (AML) is an acute leukemia characterized by aberrant proliferation of myeloid blasts in the bone marrow. Auer bodies are identifiable in the blasts of certain AML subtypes, but their "faggot-like"…
View details →DOI: 10.3389/fonc.2026.1791126 Negative / Null Result ReportOpen accessMedicine
Hashimoto G, Tsukagoshi Y, Saito A et al. · 2026 · JACC. Case reports
Background Inferior sinus venosus (SV) atrial septal defect (ASD) is a rare interatrial communication, found near the inferior vena cava (IVC)-right atrial (RA) junction, that may be overlooked on transesophageal echocardiography (TEE).…
View details →DOI: 10.1016/j.jaccas.2026.107644 Negative / Null Result ReportOpen accessMedicine
Cutarelli A, De Falco F, Brunetti R et al. · 2024 · Frontiers in veterinary science
Virological evaluation was performed on equine semen to detect the presence of papillomaviruses (PVs) using droplet digital polymerase chain reaction (ddPCR) as the aim of this study was to investigate whether the sperm from asymptomatic…
View details →DOI: 10.3389/fvets.2024.1427370 Negative / Null Result ReportMedicine
Thakur M, Mewara A, Lakshmi P et al. · 2025 · Diagnostic microbiology and infectious disease
Ascariasis, caused by Ascaris lumbricoides, is a widespread parasitic infection. Traditional diagnostic methods, such as microscopy, can miss infections with low worm burdens, leading to false negatives. This study compares four diagnostic…
View details →DOI: 10.1016/j.diagmicrobio.2025.116808 Negative / Null Result ReportMedicine
Wilk B, Lim H, Hicks J et al. · 2025 · JACC. Clinical electrophysiology
Background Atrial fibrillation is associated with abnormal synchronization of left atrial electrical activity and substantially increased risk of myocardial infarction, stroke and heart failure. Objectives This study sought to investigate,…
View details →DOI: 10.1016/j.jacep.2025.02.012 Negative / Null Result ReportMedicine
Fukuta K, Shimada Y, Nagamatu Y et al. · 2025 · European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Objectives The advantages of preoperative three-dimensional (3D) image simulations, which require enhanced computed tomography (ECT), for anatomical lung resection are well documented. However, the necessity for contrast agent presents a…
View details →DOI: 10.1093/ejcts/ezae449 Negative / Null Result ReportOpen accessMedicine
Hes C, Gui LT, Bay A et al. · 2025 · Molecular metabolism
Objective Growth differentiation factor 15 (GDF15) acts on the receptor dimer of GDNF family receptor alpha-like (GFRAL) and Rearranged during transfection (RET). While Gfral-expressing cells are known to be present in the area postrema…
View details →DOI: 10.1016/j.molmet.2024.102070 Failed Experiment ReportOpen accessMedicine
Janse van Vuuren R, Martel PO, Narbonne P · 2025 · microPublication biology
In C. elegans hermaphrodites, the distal tip cells (DTCs) capping the gonad arms provide a Notch ligand, the niche signal that maintains germline stem cell pools. Using fixed germlines, it was recently shown that the transcription of a…
View details →DOI: 10.17912/micropub.biology.001908 Negative / Null Result ReportMedicine
Clifton J, Woodward S, Hardcastle S et al. · 2025 · International journal of obstetric anesthesia
Background Disparities in labor epidural analgesia (LEA) management could reduce maternal satisfaction and increase risk. We compared times from the first administration of breakthrough pain medication (top-up) to LEA replacement to…
View details →DOI: 10.1016/j.ijoa.2024.104327 Negative / Null Result ReportMedicine
Chen Z, Trivedi AN, Rahman M et al. · 2026 · JAMA internal medicine
Importance On May 12, 2023, the Medicare program reinstated the long-standing 3-day hospitalization rule for skilled nursing facility (SNF) care after it had been waived for more than 2 years during the COVID-19 pandemic. This abrupt…
View details →DOI: 10.1001/jamainternmed.2025.7838 Negative / Null Result ReportOpen accessMedicine
Hayden JE, Deane CS · 2026 · Current opinion in clinical nutrition and metabolic care
Purpose of review To critically review recent findings related to the effects of omega-3 fatty acid supplementation on skeletal muscle, with a particular focus on skeletal muscle protein turnover and mitochondrial function. Recent findings…
View details →DOI: 10.1097/mco.0000000000001196 Negative / Null Result ReportMedicine
Chei CL, Nakamura S, Watanabe K et al. · 2025 · International journal of cancer
Chest x-ray (CXR) is widely used for lung cancer screening in Japan. We evaluated the sensitivity and specificity of CXR in detecting early lung cancer and its histological types. We cross-referenced lung cancer municipality screening data…
View details →DOI: 10.1002/ijc.35316 Negative / Null Result ReportOpen accessMedicine
Shi Q, Bao J, Li J et al. · 2025 · Respirology case reports
Occult bronchial foreign bodies are extremely rare in adults. Affected patients typically lack a clear history of aspiration, exhibit no characteristic clinical signs and present with unremarkable chest imaging, often leading to…
View details →DOI: 10.1002/rcr2.70262 