Negative / Null Result ReportOpen accessMedicine
Ventura GC, Ryan H, Yu HN et al. · 2026 · World journal of clinical pediatrics
Children born with fetal growth restriction (FGR) or small for gestational age (SGA) face an increased risk of motor and cognitive impairments, although prevalence and severity vary across studies due to differences in definitions,…
View details →DOI: 10.5409/wjcp.v15.i2.115027 Negative / Null Result ReportMedicine
Rotondo F, Biddle K, Chen J et al. · 2022 · Neuroscience
The prospect of exploiting memory reconsolidation to treat mental health disorders has received great research interest, particularly following demonstrations that the β-adrenergic receptor antagonist propranolol, which is safe for use in…
View details →DOI: 10.1016/j.neuroscience.2021.11.008 Negative / Null Result ReportOpen accessMedicine
Bakare AB, Lee Y, Hong J et al. · 2026 · Health care science
Background Assess ChatGPT and Bard's effectiveness in the initial identification of articles for Otolaryngology-Head and Neck Surgery systematic literature reviews. Methods Three PRISMA-based systematic reviews (Jabbour et al. 2017, Wong…
View details →DOI: 10.1002/hcs2.70048 Negative / Null Result Report
Zareba MR, Fafrowicz M, Marek T et al. · 2021 · Preprint
Abstract Humans can be classified as early, intermediate and late chronotypes based on the preferred sleep and wakefulness patterns. The anatomical basis of these distinctions remains largely unexplored. Using magnetic resonance imaging…
View details →DOI: 10.21203/rs.3.rs-588446/v2 Negative / Null Result ReportOpen accessMedicine
Hertereau L, Barthe M, Lamghari N et al. · 2026 · JID innovations : skin science from molecules to population health
The distribution of receptors and cellular factors across tissues determines differential susceptibility of cells to viral infection. For severe acute respiratory syndrome coronavirus 2, viral spike and nucleocapsid proteins have been…
View details →DOI: 10.1016/j.xjidi.2025.100447 Negative / Null Result Report
Kral TR, Davis K, Korponay C et al. · 2021 · Preprint
Studies purporting to show changes in brain structure following the popular, eight-week Mindfulness-Based Stress Reduction (MBSR) course are widely referenced despite major methodological limitations. Here, we present findings from a…
View details →DOI: 10.1101/2021.06.14.21258762 Negative / Null Result ReportMedicine
Naoe S, Ubukata M, Tsunamoto Y et al. · 2025 · Plant species biology
Vertical seed dispersal, involving seed movement to higher or lower elevations, plays a vital role in plant adaptation to rising temperatures. However, its assessment has been limited owing to labor‐intensive processes. A recently…
Negative / Null Result ReportOpen accessMedicine
Bhise M, Anandani G, Goswami P et al. · 2025 · Bioinformation
Malaria remains a major public health concern and accurate diagnosis is essential for effective management. This retrospective study compared the diagnostic performance of immunochromatographic rapid diagnostic tests (RDT) and peripheral…
View details →DOI: 10.6026/973206300212795 Negative / Null Result ReportMedicine
Sani LM, Senjarini K, Steinke S et al. · 2025 · Diagnostic microbiology and infectious disease
Background Dengue virus (DENV) is a major public health concern in Indonesia, with all four serotypes contributing to recurrent outbreaks. This study evaluated molecular diagnostic tests for DENV and identified circulating serotypes…
View details →DOI: 10.1016/j.diagmicrobio.2025.117050 Negative / Null Result ReportOpen accessMedicine
Yu Z, Abdel-Azim S, Duggal P et al. · 2025 · BMC genomics
Background Acute infection with hepatitis C virus (HCV) affects millions of individuals worldwide. Host genetics plays a role in spontaneous clearance of the acute infection which occurs in approximately 30% of the individuals. Common…
View details →DOI: 10.1186/s12864-024-11076-6 Failed Experiment ReportMedicine
Shivashankar P, Agee LA, Wilson N et al. · 2025 · Journal of neuroscience methods
Background Acoustic startle response (ASR) is an involuntary reflex to an intense acoustic stimulus, characterized by rapid muscle contractions. Traditional ASR testing requires animals to be placed in spatially confining chambers to…
View details →DOI: 10.1016/j.jneumeth.2025.110497 Failed Experiment ReportOpen accessMedicine
da Eira Silva V, Abele M, Bercovitz I et al. · 2025 · Workplace health & safety
Background The use of the N95 respirator outside work environments calls for a deeper understanding of the factors that interfere with its fitting, thus effectiveness. Here we determined how beard length influences N95 effectiveness. This…
View details →DOI: 10.1177/21650799241230039 Negative / Null Result ReportOpen accessMedicine
Patel KR, Pugh SL, Simko JP et al. · 2026 · Advances in radiation oncology
Purpose The cyclin-dependent kinase inhibitor p27 is a well-profiled modulator of cell cycle progression. Low nuclear p27 levels have been demonstrated to have a negative prognostic impact on outcomes in patients undergoing prostatectomy.…
View details →DOI: 10.1016/j.adro.2026.102022 Negative / Null Result ReportOpen accessMedicine
Fu CK, Lee HT, Yang YC et al. · 2025 · In vivo (Athens, Greece)
Background/aim Gastric adenocarcinoma (GACA) remains a major global health concern, particularly in Asia, due to its poor prognosis and complex etiology. The interaction between genetic factors and environmental exposures, such as smoking,…
View details →DOI: 10.21873/invivo.13990 Negative / Null Result ReportOpen accessMedicine
Papadopoulos E, Rozenberg D, Wong AKO et al. · 2025 · PloS one
Background Skeletal muscle index (SMI), grip strength, and physical performance have been shown to predict clinically relevant outcomes in geriatric oncology. However, their predictive ability for chemotherapy toxicity is poorly…
View details →DOI: 10.1371/journal.pone.0336968 Failed Experiment ReportMedicine
Shook NJ, Oosterhoff B · 2020 · Politics and the life sciences : the journal of the Association for Politics and the Life Sciences
Disgust has been consistently associated with greater political conservatism. Two explanations have been proposed for this link. According to a pathogen threat model, disgust serves a pathogen-avoidance function, encouraging more…
View details →DOI: 10.1017/pls.2020.19 Negative / Null Result ReportOpen accessMedicine
Centorame G, Warrington NM, Hemani G et al. · 2025 · Behavior genetics
Breastfeeding is hypothesised to benefit child health and cognitive functioning by providing long-chain polyunsaturated fatty acids, which are essential for brain development. In 2007, Caspi et al. found evidence in two cohorts for an…
View details →DOI: 10.1007/s10519-024-10210-0 Negative / Null Result ReportOpen accessMedicine
Torchiano A, Roberts B, Haroz R et al. · 2025 · The western journal of emergency medicine
Introduction Prescribing patients buprenorphine from the emergency department (ED) is recommended by multiple organizations. However, it is unclear how best to encourage physicians to prescribe buprenorphine from the ED. Our objectives in…
View details →DOI: 10.5811/westjem.35589 Negative / Null Result ReportOpen accessMedicine
Shen CY, Li CP, Yu JT et al. · 2026 · In vivo (Athens, Greece)
Background/aim Resveratrol, a polyphenolic compound found in grapes, berries, and peanuts, has been linked to antioxidant, anti-inflammatory, and vasoprotective effects. Yet, evidence from randomized controlled trials (RCTs) remains…
View details →DOI: 10.21873/invivo.14235 Negative / Null Result ReportOpen accessMedicine
Liu J, Catanzariti MJ, Nguyen-Hao HT et al. · 2026 · Journal of neuropathology and experimental neurology
Alcohol use disorder (AUD) is characterized by an inability to stop consuming alcohol. Neuroimaging studies of patients with AUD show mild grey and white matter atrophy, while pathological studies suggest that atrophy is restricted to the…
View details →DOI: 10.1093/jnen/nlaf147 Negative / Null Result ReportMedicine
Udry J, Barber SJ · 2025 · Cognition
Inoculation interventions aim to improve discernment between true and false information, but their effectiveness with older adults is unknown. It is also unknown whether inoculation interventions are effective when misinformation is…
View details →DOI: 10.1016/j.cognition.2025.106275 Replication FailureOpen accessMedicine
Belmaker RH · 2025 · Pharmaceuticals (Basel, Switzerland)
Lithium was the first discovered mood stabilizer for bipolar disorder. However, several antiepileptics such as valproate and carbamazepine have also proven to be mood stabilizers in all phases of bipolar disorder with profiles barely…
View details →DOI: 10.3390/ph18121850 Negative / Null Result ReportOpen accessMedicine
French B, Chiaro NVD, Holmes NP · 2022 · Experimental brain research
The grating orientation discrimination task (GOT) is a sensitive and reliable measure of tactile spatial resolution, or acuity. We used the GOT in three experiments to investigate the effects of hand posture and hand visibility on spatial…
View details →DOI: 10.1007/s00221-022-06450-3 Failed Experiment ReportOpen accessMedicine
Johnson B, Addolorato G, Lesch O et al. · 2023 · Frontiers in psychiatry
A core principle in the pursuit of scientific knowledge is that science is self-correcting and that important results should be replicable. Hypotheses need to be reinforced, adjusted, or rejected when novel results are obtained.…
View details →DOI: 10.3389/fpsyt.2023.1271229 Negative / Null Result ReportMedicine
Ferhatlar ME, Cumhur BA, Koca Y et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Purpose The aim of this study is to prospectively compare the diagnostic performance of the PECARN, CATCH, and CHALICE clinical decision rules in pediatric patients presenting with minor head trauma, within a rural secondary-level…
View details →DOI: 10.1007/s00068-026-03186-5 Negative / Null Result ReportOpen accessMedicine
Zarghami Y, Rad MG, Mafeld S et al. · 2026 · Scientific reports
Continual automated pain detection from facial expressions using computer vision during procedural sedation could optimize sedation dose titration and minimize pain. A prospective observational study was conducted. Participants' faces were…
View details →DOI: 10.1038/s41598-026-45130-y Negative / Null Result ReportMedicine
Balraam Kv V, Nayak AR, Dass J et al. · 2026 · Journal of pediatric hematology/oncology
Background Systemic mastocytosis (SM) with associated acute myeloid leukemia (AML) is a rare malignancy usually linked to KIT p.D816V mutations. Observations We report a 17-year-old female with RUNX1::RUNX1T1-positive AML and florid mast…
View details →DOI: 10.1097/mph.0000000000003232 Negative / Null Result Report
Nayak S, Deshmukh P, Yadav SR et al. · 2026 · Preprint
Ledebouria , a geophytic herb native genus to Africa and represented by a few species in the Arabian Peninsula, Madagascar, India and Sri Lanka. For a long time Indian species were named as L. revoluta until recent molecular work clarified…
View details →DOI: 10.64898/2026.06.18.733124 Negative / Null Result ReportMedicine
Slis A, Parrell B · 2026 · Journal of cognitive neuroscience
Sensory errors, mismatches between predicted sensory outcomes of movement and reafferent sensory feedback, drive changes in the feedforward control of future motor behavior that correct for those errors. Across a wide variety of motor…
View details →DOI: 10.1162/jocn.a.2630 Negative / Null Result Report
Frick A, Whyte-Fagundes P, Baraban SC · 2026 · Preprint
Syntaxin-binding protein 1 ( STXBP1 ) mutations lead to severe epilepsy, intellectual disability, developmental delay, and movement disorder. Effective treatments for these conditions do not exist. Recent studies in Munc18-1 ( STXBP1 ) C.…
View details →DOI: 10.64898/2026.05.07.723632 