Bupropion-Memantine Combination in the Treatment of Major Depressive Disorder and Treatment-Resistant Depression.
Riestra JM; Levin-Carrion Y; Sutar R; Mitchell J; Jambulingam P; Ballaz SJ; Shad MU; Rahman S · 2026 · Human psychopharmacology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Treatment-resistant depression (TRD) remains a formidable challenge in psychiatry, with nearly one-third of patients with major depressive disorder (MDD) failing to respond adequately to first-line pharmacological treatments.…
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Metadata source: Europe PMC · DOI 10.1002/hup.70039