Negative / Null Result Report
Djasarie NRA, Idris I, Arsyad A et al. · 2026 · Preprint
Overweight has become a global health problem, reaching 1 billion cases in 2022. In Indonesia, its prevalence increased from 8.8% in 2013 to 21.8% in 2018, contributing to cardiovascular risk through elevated plasma and renal endothelin-1…
View details →DOI: 10.20944/preprints202605.0148.v1 Negative / Null Result Report
Singh K, Berneburg N, May A et al. · 2026 · Preprint
Background: /Objectives: Long-term clinical data on direct posterior composite restorations are scarce. This study evaluated their performance after almost three decades using selected FDI criteria. Temporal changes were tracked across…
View details →DOI: 10.20944/preprints202605.0934.v1 Negative / Null Result ReportOpen accessMedicine
Reinprayoon U, Yaisawang S, Israsena N et al. · 2026 · Clinical ophthalmology (Auckland, N.Z.)
Purpose Descemet Membrane Endothelial Keratoplasty (DMEK) is a surgical intervention for restoring endothelial function in Fuchs endothelial corneal dystrophy (FECD). However, changes in corneal biomechanical properties assessed using…
View details →DOI: 10.2147/opth.s598840 Negative / Null Result Report
Howlett MR, Cary VE, Maitta RW · 2026 · Preprint
Abstract Immature platelets represent the youngest platelets in circulation. They are also present in all platelet units given to patients. However, there is limited knowledge of what occurs to these platelets during routine blood…
View details →DOI: 10.21203/rs.3.rs-9204379/v1 Failed Experiment ReportMedicine
Kuruppu J, Purdy JB, Pauls C et al. · 2026 · Open forum infectious diseases
Background Some people with HIV (PWH) have a poor immunologic response to antiretroviral therapy (ART). Such immunologic nonresponders are at increased risk for HIV and non-HIV related complications. Immune exhaustion may contribute to…
View details →DOI: 10.1093/ofid/ofag203 Negative / Null Result ReportMedicine
Chen S, Kortas J, Ren Y et al. · 2026 · Healthcare (Basel, Switzerland)
Objectives : Explore and compare the effects of 8-week time-restricted eating (TRE), walking exercise, and their combination on fat and lean muscle distribution in female college students with hidden obesity. Methods : A total of 68…
View details →DOI: 10.3390/healthcare14121768 Negative / Null Result Report
Dakanali M, VanBrocklin HF, Zigler SS et al. · 2026 · Preprint
Abstract Background : Multiple new PET radiopharmaceuticals (RPhs) have recently been approved by the U.S. Food and Drug Administration (FDA). Despite the generally accepted safety profile of PET RPhs supported by millions of doses…
View details →DOI: 10.21203/rs.3.rs-9826575/v1 Negative / Null Result ReportOpen accessMedicine
Aliyev F, Yigit S, Yucel E et al. · 2026 · Scientific reports
Pressure rise time (PRT) is an adjustable ventilator parameter that regulates the rate of inspiratory flow delivery and may influence ventilator mechanics and tissue oxygenation. However, its short-term physiological effects in neonates…
View details →DOI: 10.1038/s41598-026-44486-5 Negative / Null Result ReportMedicine
Tavasoli H, Rajabi MM, Sadat Hoseini AS · 2026 · Journal of pediatric nursing
Purpose To determine the effect of harmonica-based breathing and airway clearance exercises on pulmonary function in children with cystic fibrosis (CF). Methods This randomized controlled trial included 70 children with CF aged 8-18 years.…
View details →DOI: 10.1016/j.pedn.2026.05.012 Methods Dead-EndMedicine
Batista DJ, da Conceição AS · 2026 · Journal of voice : official journal of the Voice Foundation
Objectives This study aims to explore the convergence between objective acoustic measures and qualitative spectrographic analysis in the evaluation of the effects of an expressiveness-oriented training program in journalism students.…
View details →DOI: 10.1016/j.jvoice.2026.04.023 Failed Experiment ReportMedicine
Celik F, Gungor IH, Uslug M et al. · 2026 · Parasitology research
Cystic echinococcosis (CE) is a chronic zoonotic disease caused by Echinococcus granulosus, primarily affecting the liver and lungs of livestock but also capable of inducing systemic alterations through oxidative stress and metabolic…
View details →DOI: 10.1007/s00436-026-08697-z Negative / Null Result ReportMedicine
Fernández-León MF, Flórez Acosta LR, Fernández-León AM · 2026 · Foods (Basel, Switzerland)
Almond ( Prunus dulcis ) is a highly nutritious nut, rich in unsaturated fatty acids, fibre, and bioactive compounds such as tocopherols, phenolic compounds, and carotenoids. Processing methods commonly applied in the almond industry,…
View details →DOI: 10.3390/foods15122059 Negative / Null Result ReportMedicine
Khalaf NF, Salman IN, Ad'hiah AH et al. · 2026 · Scientific reports
Type 2 diabetes mellitus (T2DM) is a dysfunctional metabolic disorder characterized by low-grade inflammation. Peripheral neuropathy (PN), nephropathy (NE), and retinopathy (RT) are prominent microvascular complications (MICs) associated…
View details →DOI: 10.1038/s41598-026-55654-y Negative / Null Result ReportMedicine
Masakazu H, Akiko M, Midori Y et al. · 2026 · Scientific reports
This study was conducted to evaluate the longitudinal morphological changes in cone density (CD) in patients with the eyes shut homolog (EYS)-associated retinitis pigmentosa (RP) using adaptive optics (AO) fundus imaging and to assess its…
View details →DOI: 10.1038/s41598-026-56837-3 Negative / Null Result ReportMedicine
Kabukçu HO, Müftüoğulları S, Yıldız E · 2026 · Children (Basel, Switzerland)
Objectives: The diagnosis of pediatric acute appendicitis remains challenging due to clinical findings that overlap with nonspecific abdominal pain (NSAP). In this study, the value of fibrinogen in the diagnosis of pediatric acute…
View details →DOI: 10.3390/children13060838 Negative / Null Result ReportMedicine
Ashrafi F, Moulavi P, Jamalipanah Z et al. · 2026 · AMB Express
This study evaluated the antibacterial and antibiofilm activity of Echinacea-loaded amino-functionalized UIO-66 MOF nanoparticles against clinical Pseudomonas aeruginosa isolates. Echinacea-loaded amino-functionalized UIO-66 metal-organic…
View details →DOI: 10.1186/s13568-026-02073-x Negative / Null Result ReportMedicine
Wang MK, Wang MR, Niu YD et al. · 2026 · Pest management science
Background Autophagy is essential for insect reproduction and endosymbiont homeostasis, with Atg8 serving as a key autophagy-related gene. However, the specific role of LsAtg8 in reproduction and endosymbiont regulation in Laodelphax…
View details →DOI: 10.1002/ps.70934 Negative / Null Result ReportMedicine
Fopka-Kowalczyk M, Krajnik M · 2026 · BMC medical education
Background This article presents an evaluation of the first obligatory programme on 'Spirituality in Medicine' for medical students in Poland, implemented at the Collegium Medicum in Bydgoszcz of the Nicolaus Copernicus University in…
View details →DOI: 10.1186/s12909-026-09439-6 Negative / Null Result Report
Hyeon J, Kwon J, Cho H et al. · 2026 · Preprint
Abstract 1) Background Natural killer (NK) cells play a critical role in innate immunity and are widely used in immunological studies and cell-based therapies. Efficient in vitro expansion of NK cells is essential for both basic research…
View details →DOI: 10.21203/rs.3.rs-9547356/v1 Negative / Null Result ReportMedicine
Tanabe K, Kojima S, Saito K et al. · 2026 · Scientific reports
Transcutaneous auricular vagus nerve stimulation (taVNS) is a noninvasive electrical stimulation technique applied to the left cymba concha that may improve somatosensory impairment in stroke. Although previous studies have investigated…
View details →DOI: 10.1038/s41598-026-51309-0 Negative / Null Result Report
Morrar R, Ferrière N · 2026 · Preprint
Abstract This research examines the efficiency of foreign aid in alleviating food insecurity among Palestinian households, emphasizing heterogeneous outcomes of food security groups and heterogeneous population groups. This analysis…
View details →DOI: 10.21203/rs.3.rs-8920370/v1 Negative / Null Result ReportMedicine
Díaz Duque Á, Kaur S, Wolf M et al. · 2026 · Faraday discussions
Revealing the structural properties of water at charged interfaces is key for a better understanding of interfacial processes in various fields such as atmospheric chemistry, biology, and electrochemistry. One important aspect of the…
View details →DOI: 10.1039/d5fd00155b Failed Experiment ReportMedicine
Póvoas S, Castagna C, Connolly LJ et al. · 2026 · Journal of sports sciences
This study aimed to investigate the impact of a 15-week recreational football intervention on insulin resistance and glycaemic control in inactive premenopausal women with mild hypertension. A total of 41 women, aged 35-50 years, were…
View details →DOI: 10.1080/02640414.2025.2609442 Failed Experiment ReportOpen accessMedicine
Reuter AK, Deschner J, Schütz L et al. · 2026 · BMC medical education
Introduction The inverted classroom model (ICM) is a learner-centred approach that aims to promote engagement, independence and deeper understanding by shifting knowledge acquisition to self-directed learning before class and using class…
View details →DOI: 10.1186/s12909-026-09733-3 Failed Experiment ReportMedicine
Clark M, Wuennenberg J, Maghfour J et al. · 2026 · Clinical and experimental dermatology
Background Reflectance confocal microscopy (RCM) criteria for the in vivo diagnosis of superficial basal cell carcinoma (sBCC) lesions have been validated, with studies indicating a high level of diagnostic sensitivity. However, there…
View details →DOI: 10.1093/ced/llaf407 Negative / Null Result ReportMedicine
Akanuma S, Sugano Y, Shimmura S et al. · 2026 · Legal medicine (Tokyo, Japan)
DNA evidence can be used to link perpetrators to crime scenes or victims. We examined all Japanese criminal court cases included in a commercially available LEX/DB Internet (LEX database) from 1989, the year DNA analysis was first used as…
View details →DOI: 10.1016/j.legalmed.2026.102861 Negative / Null Result ReportMedicine
Ganidagli S, Akbas ES, Ozturk ZA · 2026 · Endocrine
Purpose Sodium-glucose cotransporter-2 inhibitors are widely used in older adults with type 2 diabetes mellitus; however, their effects on geriatric syndromes remain incompletely understood. This study evaluated the longitudinal effects of…
View details →DOI: 10.1007/s12020-026-04670-z Negative / Null Result ReportMedicine
Subramaniam NK, Gagnon N, Guilbert C et al. · 2026 · Toxicological sciences : an official journal of the Society of Toxicology
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health burden and major contributor to chronic liver disease. Evidence suggests arsenic (As) and/or cadmium (Cd) exposure may influence MASLD development,…
View details →DOI: 10.1093/toxsci/kfag073 Negative / Null Result ReportMedicine
Wen Z, Claeys K, García JG et al. · 2026 · Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology
The purpose of this study was to assess reliability of performance, knee functionality and movement quality parameters in agility T-test using markerless motion capture. Seventeen healthy participants performed two sessions of agility…
View details →DOI: 10.1016/j.jelekin.2026.103165 Negative / Null Result Report
Polat E, Özal M · 2026 · Preprint
Abstract Background Wrestling is a weight-classified sport in which athletes commonly engage in rapid weight loss (RWL) to qualify for specific categories. However, research on the short-term physiological and performance effects of RWL…
View details →DOI: 10.21203/rs.3.rs-8788628/v1