e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21707 results · page 292 of 724

Negative / Null Result Report

The time course of neural activity predictive of self-initiated movement

Jeay-Bizot L, Basbug M, Maoz U et al. · 2025 · Preprint

Decades of research have shown that early ramping activity is a very reliable antecedent of self-initiated movement. However, the dominant paradigm has been to only analyze data epochs culminating in movement, which discounts how often…

View details →DOI: 10.31234/osf.io/vdbg8_v1
Negative / Null Result Report

Does Previous Anaphylaxis Determine Differences Between Patients Undergoing Oral Food Challenges to Cow’s Milk and Hen’s Egg?

Klim L, Michalik M, Wąsowicz P et al. · 2025 · Preprint

Background: Oral food challenges (OFCs) are still the reference standard for confirming food allergy, yet the influence of previous anaphylaxis on challenge outcomes remains uncertain. Patients with a history of anaphylaxis are often…

View details →DOI: 10.20944/preprints202512.2132.v1
Negative / Null Result ReportMedicine

Transdermal Initiation of Buprenorphine Among Hospitalized Persons: A Retrospective Study.

Hathaway DB, Sato T, Szpak V et al. · 2026 · Journal of the Academy of Consultation-Liaison Psychiatry

Background Buprenorphine is an effective treatment for opioid use disorder but may be difficult to initiate among hospitalized patients due to concerns about acute pain and withdrawal risks. Objective We sought to evaluate the safety and…

View details →DOI: 10.1016/j.jaclp.2025.11.001
Negative / Null Result ReportMedicine

Throwing Load Does Not Affect Musculoskeletal Measures Around Competitive Pitching in Adolescent Baseball Pitchers.

Pexa BS, Giuliani-Dewig HK, Myers JB et al. · 2025 · Journal of athletic training

Context Baseball pitching load is linked to injury in adolescent baseball athletes; however, it is unclear if pitch counts are a good indicator of total upper extremity load during baseball pitching. Objectives The purpose of this study is…

View details →DOI: 10.4085/1062-6050-0052.25
Negative / Null Result Report

Developmental Relationship Between Home Literacy Environment and Emergent Literacy in a Transparent Orthography: A Two-Year Longitudinal Study in Japanese Preschoolers

Tanji T, Takahashi K, Matsushita H et al. · 2025 · Preprint

Abstract We examined the relationship between home literacy environment and early literacy acquisition in Japanese syllabic Hiragana and whether this relationship changes during the preschool years. One hundred five Japanese-speaking young…

View details →DOI: 10.21203/rs.3.rs-7583467/v1
Negative / Null Result ReportMedicine

Value of carbohydrate antigen 125 in pleural effusion from acute heart failure and its relationship with atrial fibrillation.

Pérez Pisón E, Llàcer P, Croset F et al. · 2026 · Medicina clinica

Introduction Pleural effusion (PE) is a frequent complication in acute heart failure (AHF), driven by hydrostatic pressure, impaired lymphatic drainage, and systemic inflammation. This study aimed to evaluate the association between…

View details →DOI: 10.1016/j.medcli.2025.107316
Negative / Null Result ReportMedicine

Hemolysis and Acute Kidney Injury Following Cardiac Surgery With Cardiopulmonary Bypass in Patients With Preexisting Renal Dysfunction.

Volleman C, Phelp PG, Dubelaar DPC et al. · 2026 · Journal of cardiothoracic and vascular anesthesia

Objectives Acute kidney injury (AKI) is a common complication following cardiac surgery with cardiopulmonary bypass (CPB). This study investigated whether cell-free hemoglobin (CFHb) levels after CPB are associated with endothelial damage…

View details →DOI: 10.1053/j.jvca.2026.02.039
Negative / Null Result ReportMedicine

How Do Sex and Family SES Influence the Relation Between School Well-Being and Academic Domains? A Multi-Group Cross-Lagged Panel Analysis from Fifth To Eighth Grade.

Rémeau M, Raffy G, Borst G · 2026 · Journal of youth and adolescence

Although the association between academic achievement and well-being has been widely studied in cross-sectional and correlational studies, prior research has rarely clarified the directionality of these links by adopting a longitudinal…

View details →DOI: 10.1007/s10964-025-02281-x
Negative / Null Result ReportMedicine

Relative influence of paraspinal muscularity and underlying bone quality on proximal junctional kyphosis and failure mode in patients undergoing thoracolumbar instrumented fusion.

Pennington Z, Mikula AL, Hamouda A et al. · 2026 · Clinical neurology and neurosurgery

Objective To assess paraspinal muscularity and bone quality contribution to PJK risk. Methods Defining PJK as ≥ 10° increase in proximal junctional angle from first upright radiograph, thoracolumbopelvic fusion patients experiencing PJK…

View details →DOI: 10.1016/j.clineuro.2025.109286
Negative / Null Result ReportMedicine

MASLD in the oldest-old: lack of association with cognition or functional autonomy and poor predictive utility of the hepatic steatosis index.

Brol MJ, Groth M, Uschner FE et al. · 2025 · GeroScience

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent condition increasingly recognized in aging populations. However, its clinical relevance in older adults-particularly in relation to sarcopenia, cognitive…

View details →DOI: 10.1007/s11357-025-02060-3
Negative / Null Result ReportMedicine

Baseline electrophysiological markers of reward and error processing are associated with improved outcomes in prize-based contingency management.

Forster SE, Forman SD, Dickey MW et al. · 2026 · Drug and alcohol dependence

Background Veterans are disproportionately affected by cocaine use disorder (CUD), a condition without approved pharmacotherapies, marked by high return to use rates. Prize-Based Contingency Management (PBCM) is an effective behavioral…

View details →DOI: 10.1016/j.drugalcdep.2025.113003
Negative / Null Result ReportMedicine

Longitudinal Associations between Mattering Dimensions and Loneliness in Adolescents: Bidirectional Effects at between- and Within-Person Levels.

Li HM, Flett GL, Cao CH et al. · 2026 · Journal of youth and adolescence

Although cross-sectional research links mattering to reduced adolescent loneliness, longitudinal studies examining temporal dynamics and distinctions between analytical levels or mattering dimensions are scarce. Without understanding…

View details →DOI: 10.1007/s10964-025-02286-6
Negative / Null Result Report

Waiting Time from Referral to Intake and Its Clinical Implications: Routine Outcome Monitoring Data from a Large Dutch Outpatient Clinic

Menéndez SM, Stehouwer K, Abikenari MA et al. · 2025 · Preprint

Background: Long waiting times remain a key barrier to accessing outpatient mental health care in the Netherlands and worldwide. Little is known about patterns of symptom change during waiting times and whether certain individuals are at…

View details →DOI: 10.31234/osf.io/ej4z7_v1
Negative / Null Result Report

Waiting Time from Referral to Intake and Its Clinical Implications: Routine Outcome Monitoring Data from a Large Dutch Outpatient Clinic

Menéndez SM, Stehouwer K, Abikenari MA et al. · 2025 · Preprint

Background: Long waiting times remain a key barrier to accessing outpatient mental health care in the Netherlands and worldwide. Little is known about patterns of symptom change during waiting times and whether certain individuals are at…

View details →DOI: 10.31234/osf.io/ej4z7_v2
Negative / Null Result ReportMedicine

Harnessing Fear and Promoting Self-Efficacy in Response to Mass Casualty Scenarios: Evaluating Stop the Bleed at an Urban University.

Tong ST, Phillips K, Gomez J et al. · 2026 · Journal of prevention (2022)

Emergency situations range from everyday traffic accidents to incidents of mass gun violence and require individuals to be prepared and willing to act in times of crisis. To encourage people to help one another during such emergencies, the…

View details →DOI: 10.1007/s10935-025-00878-3
Negative / Null Result ReportMedicine

Different effects of guilt and shame on grief among naturally bereaved Chinese adults: A three-wave cross-lagged panel analysis.

Yu X, Huang J, Jiang W et al. · 2026 · Journal of psychiatric research

Background Bereavement, i.e., the death of significant others, generally arouses grief reactions and may be accompanied by feelings of guilt and shame. However, it remains unclear whether guilt and shame can influence grief adaptation…

View details →DOI: 10.1016/j.jpsychires.2025.12.005
Negative / Null Result ReportMedicine

Persistence of pulmonary hypertension in patients with ventricular septal defect after intracardiac repair: insights from a long-term follow-up study.

Wakisaka Y, Inai K, Harada G et al. · 2025 · Cardiology in the young

Background Ventricular septal defect is the most common CHD and is complicated by pulmonary hypertension in about 5% of cases. Although long-term outcomes after repair are generally good, persistent pulmonary hypertension has been…

View details →DOI: 10.1017/s1047951125110159
Negative / Null Result ReportMedicine

The effect of race/ethnicity on systemic chemotherapy in urothelial carcinoma patients exposed to radiotherapy.

de Angelis M, Siech C, Di Bello F et al. · 2025 · World journal of urology

Introduction Based on prospective trials' result, it is unknown whether race/ethnicity affects the magnitude of cancer-specific survival differences after trimodal therapy (TMT) versus external beam radiation therapy alone (EBRT) for…

View details →DOI: 10.1007/s00345-025-05767-2
Negative / Null Result ReportMedicine

Ethnicity and income as predictors of clinical outcomes of a youth-focused personalizable modular treatment.

Cho E, Chorpita BF, Reeder K et al. · 2025 · Journal of consulting and clinical psychology

Objective Personalizable modular treatments may be helpful in addressing the mental health needs of minoritized youths. We used data from five randomized effectiveness trials of the Modular Approach to Therapy for Children, a…

View details →DOI: 10.1037/ccp0000979
Negative / Null Result ReportMedicine

Subjective well-being mediates the longitudinal effect of insomnia symptoms on internalizing symptoms in community-dwelling older adults.

Ying Y, Meng R, Xu J et al. · 2026 · The journals of gerontology. Series B, Psychological sciences and social sciences

Objectives The associations between insomnia symptoms and internalizing symptoms are well-established, particularly in older adults; however, the mediating factors remain inconsistent. This study seeks to explore the longitudinal…

View details →DOI: 10.1093/geronb/gbaf221