Negative / Null Result ReportMedicine
Zhao H, Wang L, Zhang S et al. · 2026 · BMC psychology
Background Professional divers work in safety-critical environments that require sustained attention, rapid judgment, and stable emotional control. Neuroticism is a vulnerability trait related to negative affectivity, perceived stress…
View details →DOI: 10.1186/s40359-026-05029-9 Negative / Null Result ReportMedicine
Jadhav R, Demirbas Uzel G, Charest J et al. · 2026 · Microorganisms
The filamentous fungus Trichoderma reesei is one of the most important workhorses for industrial enzyme production, but the cellular mechanisms that balance protein folding stress with secretion, such as the unfolded protein response (UPR)…
View details →DOI: 10.3390/microorganisms14061371 Negative / Null Result ReportMedicine
Bayhan GI, Aydın Altuntaş C, Cevahir N · 2026 · Journal of infection in developing countries
Objective Hand hygiene (HH) is a fundamental infection prevention measure in healthcare settings, playing a crucial role in reducing healthcare-associated infections (HAIs). Despite its importance, HH compliance remains suboptimal…
View details →DOI: 10.3855/jidc.22190 Failed Experiment ReportMedicine
Kim LJ, Rennert RC, Couldwell WT · 2026 · Journal of neurosurgery
Objective Multiple closure techniques may prevent CSF leak after transsphenoidal surgery for sellar lesions. In patients with obstructive sleep apnea requiring positive pressure ventilation (PPV), the optimal closure technique remains…
View details →DOI: 10.3171/2026.1.jns251476 Failed Experiment Report
Poole A, Chang K, Wang F et al. · 2026 · Preprint
Heschl’s gyrus (HG), which contains the primary auditory cortex, shows marked individual variability in its folding pattern, ranging from a single gyrus to partial or complete duplication. Greater HG duplication has been reported in expert…
View details →DOI: 10.64898/2026.04.30.721986 Negative / Null Result ReportOpen accessMedicine
Gassé E, Brill A · 2026 · The western journal of emergency medicine
Introduction As public access to tetrahydrocannabinol (THC) products expands under state legalization, there is concern for increased use in adolescents under 18 years of age and its subsequent effects. Adverse effects of THC use have been…
View details →DOI: 10.5811/westjem.62946 Negative / Null Result ReportMedicine
Panaitof SC, Kermagi MM · 2026 · Archives of insect biochemistry and physiology
Dopamine has diverse roles in the regulation of reproduction and social behaviors in insects. In the burying beetle, Nicrophorus orbicollis, a species with extended care, our previous work has shown that brain dopamine levels increase…
View details →DOI: 10.1002/arch.70177 Negative / Null Result ReportMedicine
Majoe M, Stolarek N, Vizueta J et al. · 2026 · Journal of evolutionary biology
Colonies of insects with morphologically distinct castes have been called superorganisms because the function of their queens and workers is analogous to the germline and soma in metazoan bodies. In the case of formicoid ants, workers…
View details →DOI: 10.1093/jeb/voag043 Negative / Null Result ReportMedicine
Rodrigue JR, Fleishman A, Schold JD et al. · 2026 · Transplantation
Background Lost wages following living donation may deter patients from pursuing living donor kidney transplantation (LDKT) and potential donors from being evaluated. Methods We randomized patients undergoing transplant evaluation to 1 of…
View details →DOI: 10.1097/tp.0000000000005749 Negative / Null Result Report
Quispe M, Silva Rochefort B, Rojas MJ et al. · 2026 · Preprint
Seasonal reproduction in birds is commonly regulated by photoperiod, and passerines are generally considered long-day breeders. The Java sparrow (Padda oryzivora) has been proposed as a possible exception, but experimental evidence for…
View details →DOI: 10.22541/authorea.15003225/v1 Negative / Null Result ReportOpen accessMedicine
Ichishima J, Nakakariya M, Kimura H · 2026 · Scientific reports
Narcolepsy type 1 (NT1) is caused by a significant loss of orexin-producing neurons. In clinical trials, multiple orexin receptor 2 (OX2R)-selective agonists (e.g., danavorexton, TAK-994, and oveporexton) improved wakefulness and decreased…
View details →DOI: 10.1038/s41598-026-44080-9 Negative / Null Result Report
Toft S, Skalshøi MR, Brun-Witt L et al. · 2026 · Preprint
Balancing of macronutrient intake assumes that animals change their food preferences to increase consumption of the deficient nutrients and/or decrease consumption of nu-trients in excess. Harvestmen are generalist predators that consume…
View details →DOI: 10.20944/preprints202604.1469.v1 Negative / Null Result ReportMedicine
Miloro R, Mala B, Ceplecha V et al. · 2026 · Journal of the American Veterinary Medical Association
Objective To evaluate short- and long-term patient outcomes retrospectively, investigate anesthetic and surgical times, and assess clinically relevant surgical wound complications associated with the use of needle-tip monopolar…
View details →DOI: 10.2460/javma.25.11.0713 Negative / Null Result ReportMedicine
Castanha D, Lessa TC, Martins-de-Araújo ES et al. · 2026 · Medicina oral, patologia oral y cirugia bucal
Background Oral sedation is widely utilized in dental surgical practice for anxiety management during third molar extractions. Midazolam is one of the most frequently employed drugs; however, the clinical benefits of its association with…
View details →DOI: 10.4317/medoral.28014 Negative / Null Result Report
Bosshard A, Zhou L, Brick C et al. · 2026 · Preprint
Repair can help extend clothing lifecycles. However, this behavior is infrequent in high-income countries, especially among younger adults who often lack practical repair skills. In this quasi-experiment, we tested whether a group workshop…
View details →DOI: 10.31234/osf.io/pqb29_v2 Negative / Null Result ReportMedicine
Chen CH, Yu PH, Fan CY et al. · 2026 · Frontiers in medicine
Background Automatic transport ventilators (ATVs) are a potential option for ventilating patients experiencing out-of-hospital cardiac arrest (OHCA); however, their tidal volume delivery performance at different pressure limits compared…
View details →DOI: 10.3389/fmed.2026.1826906 Negative / Null Result ReportMedicine
Sinyakova G, Diagne M, Banville M et al. · 2026 · Bone
There is a need for a comprehensive understanding of alveolar bone biology, given its unique characteristics compared to other skeletal sites. To this end, we established novel female murine alveolar osteoblastic cell lines and analyzed…
View details →DOI: 10.1016/j.bone.2026.117957 Negative / Null Result ReportMedicine
Alshaikhsalama A, Thompson K, Hashim H et al. · 2026 · European journal of ophthalmology
PurposeTo investigate the association between age-related macular degeneration (AMD), retinal artery occlusion (RAO), and retinal vein occlusion (RVO) and the future development of Alzheimer's disease (AD), vascular dementia (VaD), and…
View details →DOI: 10.1177/11206721261438587 Negative / Null Result ReportMedicine
Werner C, Ullrich P, Degli Angeli L et al. · 2026 · Age and ageing
Persistent mobility limitations after inpatient rehabilitation are common in older adults with cognitive impairment (CI). Home-based exercise interventions can improve locomotor capacity during this vulnerable period; however, evidence…
View details →DOI: 10.1093/ageing/afag189 Negative / Null Result ReportMedicine
Patel RP, Polli JE · 2026 · Journal of pharmaceutical sciences
The dissolution of ionizable drugs is critically influenced by the pH of the microenvironment at the solid-liquid interface, which in part can be impacted by the dissolving drug itself. For weak bases, dissolution may increase surface pH,…
View details →DOI: 10.1016/j.xphs.2026.104265 Negative / Null Result Report
Wen Z, Yang Z, Cheng J et al. · 2026 · Preprint
Abstract Background The use of intensive statin therapy in acute ischemic stroke (AIS) is common; however, its association with post-stroke pneumonia (PSP) remains uncertain. This study aimed to determine whether intensive-dose…
View details →DOI: 10.21203/rs.3.rs-8842936/v1 Failed Experiment ReportMedicine
Thng C, Eskandari S, Jin F et al. · 2026 · NPJ vaccines
Neisseria gonorrhoeae (NG) causes significant morbidity globally, and no licensed vaccine currently exists. Observational studies suggest the four-component meningococcal B (4CMenB) vaccine may provide cross-protection against NG. We…
View details →DOI: 10.1038/s41541-026-01422-y Negative / Null Result ReportMedicine
Mastrokostas PG, Said M, Mastrokostas LE et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Purpose To determine the 90-day incidence of surgical site infection (SSI) after cervical disc arthroplasty (CDA), compare single versus multilevel procedures, and identify independent predictors of SSI. Methods We identified adult…
View details →DOI: 10.1007/s00586-026-10012-4 Negative / Null Result ReportMedicine
Medina-Moctezuma ZB, Guzmán-Sánchez A, González-Aretia D et al. · 2026 · Biochemical and biophysical research communications
Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) stimulate the synthesis of sphingosine-1 phosphate (S1P) in Gs-coupled receptors dependent manner, enabling S1P to mediate specific bioactivities of FSH and LH. Because…
View details →DOI: 10.1016/j.bbrc.2026.153994 Negative / Null Result Report
ERSALI Y, KURU İS, SEVIM MA · 2026 · Preprint
Abstract The concept of physiological maturity refers to the period during which seeds reach their maximum germination capacity. Accurately determining this stage facilitates efficient seedling production and helps balance supply and…
View details →DOI: 10.21203/rs.3.rs-8976974/v1 Negative / Null Result ReportMedicine
Yavuz T, Sarac O, Alpdogan O et al. · 2026 · Journal of infection in developing countries
Introduction Chronic lung diseases (CLD) are associated with increased susceptibility to respiratory infections and may influence COVID-19 outcomes. This research aims to assess the clinical, laboratory findings, and prognostic outcomes in…
View details →DOI: 10.3855/jidc.21431 Negative / Null Result Report
Zhang X, Shen T, Ye S et al. · 2026 · Preprint
Objective: : To investigate the effect of 0.1% ropivacaine with a lower concentration sufentanil for epidural analgesia during the latent phase of labor. Design: : Double-blind, randomized, controlled, non-inferiority trial. Setting: : A…
View details →DOI: 10.22541/au.177305981.18200091/v1 Negative / Null Result ReportMedicine
Casey ER, Uritsky T, Soyfer L et al. · 2026 · Substance use & addiction journal
Background Hospitals increasingly start methadone treatment for opioid use disorder (OUD). Rapid methadone titration has been described in hospitals with addiction consult teams; however, most hospitals lack these specialty services. We…
View details →DOI: 10.1177/29767342261433344 Negative / Null Result Report
Baharvand F, Najafi R, Parvaneh S et al. · 2026 · Preprint
Abstract Background: The optimal peri-procedural management of metformin in patients with type 2 diabetes undergoing elective coronary angiography remains debated. Concerns regarding contrast-induced acute kidney injury (CI-AKI) and the…
View details →DOI: 10.21203/rs.3.rs-8979165/v1 Negative / Null Result ReportMedicine
Tannuri ACA, Abe Takahasi BN, de Almeida Estrambk G et al. · 2026 · Journal of pediatric surgery
Background Esophageal atresia (EA) is frequently associated with congenital heart disease (CHD) and chromosomal anomalies, mainly Down syndrome (DS). While these conditions affect outcomes following primary repair, their specific impact on…
View details →DOI: 10.1016/j.jpedsurg.2026.163202 