A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21707 results · page 291 of 724
Li X, Ji X, Shan J et al. · 2026 · Annals of medicine
Background and objectives Aquaporin-1 (AQP1) is a well-characterized transmembrane water channel widely expressed in the peripheral nervous system (PNS), where it contributes to water balance and regulation of the local neural…
Vetter P, Cabecinhas ARG, Schibler M et al. · 2026 · Antimicrobial agents and chemotherapy
Immunocompromised patients are at risk of developing severe influenza, with protracted viral shedding and development of resistance-associated mutations under antiviral treatment. We report a case series of severely immunocompromised…
Herrero C, Wasterlain A, Bloom DA et al. · 2024 · Bulletin of the Hospital for Joint Disease (2013)
Purpose The purpose of this study was to compare regimens of eccentric exercise and dry-needling, with and without an ultrasound-guided leukocyte-poor platelet-rich plasma (LP-PRP) injection, in patients with patellar tendinopathy. Methods…
Yu D, Song Z, Liu Y et al. · 2024 · Preprint
Abstract Background Ursodeoxycholic acid (UDCA) was reported to reduce susceptibility to SARS-CoV-2 infection by downregulating farnesoid X receptor (FXR) -ACE2 signaling. However, we found a different story in real-world clinical studies.…
Bharti A, Palta A, Bedi RK et al. · 2024 · The Indian journal of medical research
Background & objectives The newer technique using an innovative volume conductivity scatter (VCS) technology is emerging as a surrogate for sepsis diagnosis. The VCS technology offers a more objective method to measure cell volume (V),…
Sust L, Schoedel R · 2024 · Preprint
Digitalization has created an unparalleled freedom of choice in music consumption, pronouncing inter- and intraindividual differences in everyday listening behavior. To shed light on the factors involved in natural music choices, the…
Rahner A, Eickholz P, Gueth JF et al. · 2025 · Clinical oral implants research
Objectives In vitro analysis of the influence of vertical peri-implant soft tissue thickness (STT) on nonsurgical and surgical implant surface decontamination efficacy. Material and methods A total of 360 implants were dipped in indelible…
Jeong J, Goh J, Nam C et al. · 2025 · Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
Tumors originating from the anal sacs and perianal glands are common tumors of the perianal region. However, differentiation of perianal tumors based on CT findings remains challenging because perianal tumors can show overlapping CT…
Whitaker R · 2025 · Health and human rights
The discourse around health as a human rights issue usually focuses on access to medical treatment. However, the "right to health" begins with the right to informed consent about the merits of a treatment, which has been lacking as a…
Komarova NL, Pritchard J, Wodarz D · 2024 · Preprint
Principles of evolution in spatially structured expanding populations have recently received much attention, but more work remains to be performed, especially for complex, multi-step evolutionary processes, where mutations are accumulated…
Tilanus AM, Shields RK, Lodise TP et al. · 2025 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Based on the fact that beta-lactam antibiotics demonstrate time-dependent killing, different dosing strategies have been implemented to increase the time that free (unbound) antibiotic concentrations remain above the minimal inhibitory…
Sewell KM, Oriakhi K, Ngo Tenlep SY et al. · 2026 · Ecotoxicology and environmental safety
Organophosphate flame retardants (OPFRs) are used in many consumer products, and their presence in our environment raises concerns about potential health dangers. In humans, exposure to OPFRs, such as tris(1,3-dichloro-2-propyl) phosphate…
Kotha S, Baisya R, Yerram KV et al. · 2025 · Mediterranean journal of rheumatology
Background Lupus enteritis (LE) is the most common serious gastrointestinal manifestation of SLE. Indian literature on LE is limited, while most of the data comes from China and Western series with recent efforts on developing prediction…
Gow J, Roofeh D · 2025 · BMC rheumatology
Background Giant cell arteritis (GCA) is a large vessel vasculitis characterized by granulomatous inflammation classically affecting the carotid artery branches. GCA most often presents with one or more classic clinical features which…
Patel SA, Roy JM, Musmar B et al. · 2024 · Neurosurgical focus
Objective Preclinical studies suggest that robotic carotid artery stenting (CAS) could be superior to manual CAS. However, very limited comparative data exist for patients who have undergone robotic versus manual CAS. In addition, no data…
Goudman L, Pilitsis JG, Billet B et al. · 2024 · Anaesthesia
The numerical rating scale and visual analogue scale are used to quantify pain intensity. However, it has not yet been explored whether these scores are interchangeable in adults with chronic pain. Data from the prospective multicentre…
Croes M, Kreuwels B, Verheyen S · 2024 · Preprint
Research shows that when people take pictures of items around them, they have impaired memory for these items. Two theoretical accounts have emerged for this so-called photo-taking impairment effect: the offloading hypothesis and the…
Millan B, Hoogenes J, Uy M et al. · 2025 · Canadian Urological Association journal = Journal de l'Association des urologues du Canada
Introduction We aimed to assess early and late continence rates post-robot-assisted radical prostatectomy (RARP), comparing posterior reconstruction (PR) urethrovesical anastomosis (UVA) to conventional urethrovesical anastomosis (C-UVA).…
Caldani S, Khoury E, Delorme R et al. · 2025 · Brain sciences
Background/Objectives: Children with dyslexia report poor motor control; several studies have shown poor eye movements control during reading and important body instability in these children. The present study aimed to test in children…
Egger M, Bergmann J, Krewer C et al. · 2024 · Journal of neurologic physical therapy : JNPT
Background and purpose Functional recovery after stroke is often limited, despite various treatment methods such as robot-assisted therapy. Repetitive sensory stimulation (RSS) might be a promising add-on therapy that is thought to…
Sharma S, Narwariya KS, Shakya R et al. · 2025 · Bioinformation
Acute intestinal obstruction presents a clinical challenge, and the optimal management approach remains uncertain. Therefore, it is of interest to compare outcomes of conservative versus surgical management in 100 patients with acute…
Sinka GC, Pavlik A, Mayer Á et al. · 2026 · Sports (Basel, Switzerland)
Background Anterior cruciate ligament (ACL) injuries in youth athletes are multifactorial, and the relative contributions of neuromuscular and neurocognitive variables remain inadequately comprehended. Methods In this prospective cohort…
Abushouk A, Layoun H, Harb SC et al. · 2024 · Journal of cardiac failure
Novel transcatheter therapies for tricuspid regurgitation (TR) appear promising, yet their applicability to an all-comer TR population remains unclear. We aimed to assess the feasibility of emerging transcatheter tricuspid therapies in a…
Talapatra A, Mathew S, Kanakalakshmi ST et al. · 2024 · Preprint
Background Post-operative sore throat (POST) is one of the most common complaints post-endotracheal intubation and can be decreased through various interventions. This study aimed to determine the effect of fluticasone-impregnated versus…
Cardani S, Janes TA, Asif R et al. · 2026 · Acta physiologica (Oxford, England)
Aim Rhythmic breathing movements driven by the brainstem rely on chemosensory inputs to homeostatically adjust motor output to the prevailing metabolic demand. The central CO 2 chemoreflex is a critical component of this neural circuitry,…
Chaccour C, Nicolas P, Martinho S et al. · 2025 · EClinicalMedicine
Background Endectocides are a novel vector control tool that reduce the survival and fertility of blood sucking arthropods that feed upon treated humans or animals. Ivermectin mass drug administration is under evaluation as a complementary…
Antunes FTT, Gadotti VM, Zamponi GW · 2025 · Molecular brain
Alpha-bisabolol and camphene have demonstrated analgesic effects in inflammatory pain models by blocking Cav3.2 calcium channels. As the pain pathway overlaps with mechanisms for itch, and because Cav3.2 channels have been associated with…
Yang W, Ding X, Yu Y et al. · 2024 · Clinical radiology
Aims To investigate the long-term prognostic value of coronary computed tomography angiography (CCTA)-derived high-risk attributes and radiomic features of pericoronary adipose tissue (PCAT) in diabetic patients for predicting major…
SUN X, GODJE ISG, HU H et al. · 2024 · Preprint
Despite breakthroughs in care and treatment, the consequences of a subarachnoid hemorrhage (SAH) are still associated with morbidity and mortality. Early brain injury is still a major source of clinical deterioration in people with SAH.…
Sagadiev S, Hudson R Jr, Wang Y et al. · 2026 · Genetics
Integrin adhesion complexes (IACs) are a network of proteins that anchor cells to the extracellular matrix. In Caenorhabditis elegans muscle IACs exist at the bases of dense bodies and M-lines, and at the boundaries of adjacent muscle…