Negative / Null Result ReportMedicine
Zhang Y, Zhao J, Gao Q et al. · 2026 · Virchows Archiv : an international journal of pathology
Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations occur in 25-30% of non-small cell lung cancer (NSCLC) patients. Pooled analyses in previous research have largely focused on the prognostic and predictive value of overall or…
View details →DOI: 10.1007/s00428-026-04475-5 Negative / Null Result ReportOpen accessMedicine
Yan L, Yin H, Shi L et al. · 2026 · Drug design, development and therapy
Purpose To evaluate the efficacy and safety of PHPV in the treatment of persistent high-risk papillomavirus (hrHPV) infection of the cervix. Patients and methods A randomized controlled trial (RCT) was conducted on patients with persistent…
View details →DOI: 10.2147/dddt.s542859 Negative / Null Result ReportMedicine
Guan J, Chen Y, Ye J et al. · 2026 · Annali italiani di chirurgia
Aim Rotator cuff tears and long head of the biceps tendon (LHBT) injuries are primary causes of shoulder pain. During rotator cuff repair, concurrent LHBT injuries are frequently identified. Surgical management of LHBT injuries can…
View details →DOI: 10.62713/aic.4500 Negative / Null Result ReportMedicine
Phyo AP, Hoglund RM, Saito M et al. · 2026 · Tropical medicine & international health : TM & IH
Background HIV co-infection affects host responses and pharmacokinetics (PK) of tuberculosis (TB) treatment. This study assessed the PK of first-line anti-TB drugs and clinical outcomes in patients with and without HIV co-infection.…
View details →DOI: 10.1111/tmi.70165 Negative / Null Result ReportMedicine
Nicklas A, Bienger K, Rudari M et al. · 2026 · Burns : journal of the International Society for Burn Injuries
Background Split-thickness skin grafting (STSG) remains the standard for deep second-degree burns, but grafted skin often shows suboptimal biomechanical properties. The dermal substitute MatriDerm® may improve elasticity, structural…
View details →DOI: 10.1016/j.burns.2026.107977 Negative / Null Result ReportMedicine
Deml O, Schenk P, Fritsche C et al. · 2026 · Journal of shoulder and elbow arthroplasty
Background Geriatric distal humerus fractures are difficult to manage. Open reduction and internal fixation remain the standard, but total elbow arthroplasty (TEA) appears to be a viable alternative. This study evaluated the long-term…
View details →DOI: 10.1016/j.jsea.2026.100027 Negative / Null Result ReportMedicine
Jiang D, Zhang W, Liu L et al. · 2026 · BMC cardiovascular disorders
Background Accurate quantification of aortic valve calcification (AVC) on contrast-enhanced computed tomography angiography (CTA) is pivotal for planning surgical and transcatheter aortic valve replacement. The optimal Hounsfield unit (HU)…
View details →DOI: 10.1186/s12872-026-06108-w Negative / Null Result Report
liu p, Hu S, Zeng H et al. · 2026 · Preprint
Abstract Background : Timely reperfusion is critical for patients with acute ST-segment elevation myocardial infarction (STEMI). While door-to-balloon (D2W) time has been substantially optimized in chest pain centers, the impact of first…
View details →DOI: 10.21203/rs.3.rs-8972635/v1 Negative / Null Result ReportMedicine
Arnouts EC, Drysdale ND, Gerstner Saucedo J et al. · 2026 · Pediatric radiology
Background Diffuse myocardial fibrosis, as measured by T1 (longitudinal relaxation time) mapping and extracellular volume, may be associated with ventricular dysfunction in the Fontan circulation. However, the relationship between diffuse…
View details →DOI: 10.1007/s00247-026-06675-2 Negative / Null Result ReportMedicine
Hadi M, Natashia D, Purwati NH et al. · 2026 · Nurse education today
Background Effective interprofessional collaboration is essential for optimal patient care, but inadequate training often hinders teamwork and communication among healthcare professionals. Interprofessional Education (IPE) can address this…
View details →DOI: 10.1016/j.nedt.2026.107138 Negative / Null Result ReportOpen accessMedicine
Levent M, Akın S · 2026 · BMC geriatrics
Background Malnutrition drives adverse outcomes in older adults, but routine screening is often hindered by time constraints and reliance on subjective data. The Geriatric Nutritional Risk Index (GNRI), derived from serum albumin and body…
View details →DOI: 10.1186/s12877-026-07597-2 Methods Dead-EndOpen accessMedicine
Yang H, Yang L, Li Z et al. · 2025 · Medicine
Observational studies have reported associations between coffee intake and osteoarthritis (OA), rheumatoid arthritis (RA), and osteoporosis (OP). However, it remains unknown whether these relationships are causal. In this study, we applied…
View details →DOI: 10.1097/md.0000000000044533 Negative / Null Result ReportOpen accessMedicine
Li X, Liang L, Yang ZY et al. · 2026 · Translational cancer research
Background Growing evidence suggests that deeply invasive node-negative colon cancer, particularly T4bN0 disease, may have a worse prognosis than early node-positive tumors, challenging the current American Joint Committee on Cancer (AJCC)…
View details →DOI: 10.21037/tcr-2026-0545 Negative / Null Result ReportMedicine
Harding BN, Jiang Z, Pineda D et al. · 2026 · Environmental health : a global access science source
Background The major pathways contributing to cardiovascular disease among night shift workers remain poorly understood. MicroRNAs (miRNAs) have been identified as novel regulators of cardiovascular risk factors. Our objective was to…
View details →DOI: 10.1186/s12940-026-01308-5 Negative / Null Result ReportMedicine
Perrignon C, Baudouin R, Perrignon M et al. · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Introduction Chronic rhinosinusitis with nasal polyps (CRSwNP) is a long-lasting inflammatory disease that affects 1-4% of the population and markedly impairs quality of life, daily functioning, and socio-professional activities. As no…
View details →DOI: 10.1007/s00405-026-10190-3 Negative / Null Result ReportMedicine
Satoh T, Kawaguchi S, Nakatani E et al. · 2026 · Abdominal radiology (New York)
Background/objectives Accurate differentiation between pancreatic carcinoma in situ (CIS) and small invasive pancreatic ductal adenocarcinoma (PDAC) is critical for optimizing patient management. This study aimed to assess the diagnostic…
View details →DOI: 10.1007/s00261-026-05453-w Negative / Null Result ReportMedicine
Acil F, Dedeoğlu A, Tosun Söner H et al. · 2026 · Surgical endoscopy
Background Pneumoperitoneum and steep Trendelenburg positioning during laparoscopic hysterectomy may increase intracranial pressure. Optic nerve sheath diameter (ONSD), measured by transorbital ultrasonography, is a validated noninvasive…
View details →DOI: 10.1007/s00464-026-12731-7 Negative / Null Result ReportMedicine
Lychagin AV, Gritsyuk AA, Elizarov MP et al. · 2026 · Journal of clinical medicine
Background: Robot-assisted total knee arthroplasty (raTKA) improves the precision of component positioning and coronal alignment restoration, but it remains uncertain whether that technical accuracy modifies the clinical effect of…
View details →DOI: 10.3390/jcm15124515 Negative / Null Result ReportMedicine
Damianos JA · 2026 · Clinical biochemistry
Auto-brewery syndrome (ABS) is a rare disorder featuring episodes of intoxication caused by intestinal fermentation of dietary carbohydrates into ethanol. This article presents the case of a patient referred for evaluation of ABS. He…
View details →DOI: 10.1016/j.clinbiochem.2026.111152 Negative / Null Result Report
Dong B, Song Z, Yin Y · 2026 · Preprint
Spatial transcriptomics can reveal localized tumor–immune relationships, but thousands of spots from one tissue section do not provide thousands of biological replicates. We evaluated the distinction between within-section association and…
View details →DOI: 10.64898/2026.06.13.732045 Negative / Null Result Report
Lagacé-Cusiac R, Grahn JA, Ansari D · 2026 · Preprint
Relative magnitudes, such as ratios and proportions, are crucial to everyday life. According to the ratio processing system (RPS) theory, ratios across different formats share a common neural code. Prior neuroimaging studies have shown…
View details →DOI: 10.31234/osf.io/djcsb_v2 Negative / Null Result ReportMedicine
Canivez GL, Watkins MW, McGill RJ et al. · 2026 · Assessment
The Wechsler Adult Intelligence Scale-Fifth Edition (WAIS-5) latent factor structure was assessed using complementary hierarchical exploratory factor analyses (EFA) with the Schmid and Leiman procedure and confirmatory factor analyses…
View details →DOI: 10.1177/10731911251412219 Negative / Null Result ReportMedicine
Li Y, Chen R, Hou C et al. · 2026 · Medicine
We performed a 2-step Mendelian randomization (MR) study to investigate the associations of Fms-related tyrosine kinase 3 ligand (FLT3L) and phosphate levels with the risk of hypertrophic cardiomyopathy (HCM). Genetic instruments for 75…
View details →DOI: 10.1097/md.0000000000049477 Negative / Null Result ReportMedicine
Aghaalikhani M, Rostami Abusaidi S, Azimi F et al. · 2026 · Journal of medical case reports
Background Osteosarcoma is the most common primary malignant bone tumor, typically affecting adolescents and young adults. While its development is often associated with rapid bone growth and genetic factors, the potential link between…
View details →DOI: 10.1186/s13256-026-06257-8 Negative / Null Result ReportMedicine
Liu Y, Wei M · 2026 · Journal of the Optical Society of America. A, Optics, image science, and vision
Color matching functions (CMFs) play important roles in color specification, characterization, and reproduction. Though the CIE 1931 2° CMFs are widely used in practice, its well-known weaknesses and poor performance have motivated great…
View details →DOI: 10.1364/josaa.590626 Negative / Null Result ReportMedicine
Rahal D · 2026 · Journal of health psychology
Although social support is related to better health, research is mixed regarding how social support relates to physiological systems including the parasympathetic nervous system. The present study assessed whether perceived parental and…
View details →DOI: 10.1177/13591053261430998 Negative / Null Result Report
shakeel h · 2026 · Preprint
Abstract Correct ligand-site assignment is a prerequisite for interpreting molecular dynamics simulations of non-ATP kinase ligands. In computational chemistry and structure-based drug discovery, apparent ligand stability does not by…
View details →DOI: 10.21203/rs.3.rs-9770049/v1 Negative / Null Result ReportMedicine
Li YB, Zheng ZW, Zuo M · 2026 · BMC gastroenterology
Background Total body water (TBW) is an important indicator of fluid homeostasis and is closely related to various metabolic and chronic diseases. However, the relationship between TBW and gastrointestinal symptoms (stomach or intestinal…
View details →DOI: 10.1186/s12876-026-05023-w Negative / Null Result ReportMedicine
Liu P, Dang C, Liu J et al. · 2026 · Current medicinal chemistry
Introduction This study aimed to investigate the causal relationship and biological mechanism between oral contraceptives (OCs) and adverse pregnancy outcomes using Mendelian randomization (MR) methods. Methods We conducted a drug-target…
View details →DOI: 10.2174/0109298673396130260330140027 Negative / Null Result ReportMedicine
Zadrożny Ł, Orlańska A, Ponto-Wolska M et al. · 2026 · European journal of dentistry
Objective This article aims to evaluate dental students' experiences, perceptions, and expectations related to training with virtual reality-based haptic simulators (VRHS) introduced into the preclinical and clinical dental curriculum.…
View details →DOI: 10.1055/s-0046-1824443 