A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21287 results · page 280 of 710
Gopinath D, On CY, Veettil SK et al. · 2026 · Oral diseases
Background The cumulative evidence from meta-analyses on interventions for oral submucous fibrosis (OSF) remains uncertain in terms of strength, precision, and quality. This umbrella review synthesizes the current evidence on available…
Qiu F, Ling C, Wang S et al. · 2026 · Molecules (Basel, Switzerland)
Mulberrofuran A (MFA), a natural product originally isolated from the root bark of Morus alba L. (Sang-Bai-Pi), is a structurally distinctive mulberry-derived 2-arylbenzofuran bearing a prenyl-related side chain. Although MFA has attracted…
Baltrak YA, Deliaga H · 2026 · Preprint
Background: /Objectives: Vesicoureteral reflux (VUR) is an important pediatric urologic condition in which accurate grading on voiding cystourethrography (VCUG) may influence counseling, surveillance, antimicrobial prophylaxis, and…
Chauhan V, Goyal D, Thakur S et al. · 2026 · The western journal of emergency medicine
Introduction Organophosphate (OP) poisoning is a significant global health issue, particularly in tropical regions. Despite established treatments such as atropine and oximes, the effectiveness of other interventions remains uncertain.…
Gazit N, Ben-Gal G, Eliashar R · 2026 · JMIR medical education
Background Assessment of technical aptitude, cognitive abilities, and personality characteristics is important in selecting candidates for surgical training. Currently, the selection of surgical training candidates does not systematically…
Du Y, Xu Z, Wen T et al. · 2026 · Diabetes, metabolic syndrome and obesity : targets and therapy
Purpose The care of diabetic foot ulcers (DFU) continues to be a notable clinical challenge. The efficacy and safety of stem cell therapies versus conventional treatments for DFU are debated. Cross-sectional analyses of meta-analyses…
Zhang Y, Wu Z · 2026 · Frontiers in public health
Background Digital technologies in oncology require patients and health workers to possess adequate electronic health literacy (eHealth literacy). Yet, the extent to which this literacy influences cancer-specific insights, ranging from…
Hou YN, Gubili J, Mao JJ · 2026 · Seminars in radiation oncology
Studies show that patients with cancer use herbal products more often than the general population. Lowering the risk of disease recurrence, symptom control, and improving quality of life are often the reasons cited for such use. However, a…
Kyei EF, Kyei GK, Forson MM et al. · 2026 · Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing
Aim To examine nurse practitioner opioid prescribing authority across three countries, analyzing safety outcomes, workforce distribution patterns, access equity, and service to vulnerable populations using integrated nursing policy and…
Tafuri MG, Monda V, La Marra M et al. · 2026 · Nutrients
Background/Objectives: Sport participation and nutrition are increasingly recognized as key determinants of cognitive function and academic achievement in student populations. However, the biological mechanisms underpinning these…
Leahy TP, Keenan C, Robertshaw E et al. · 2026 · Value in health regional issues
Objectives Growing reliance on single-arm trials (SATs) is driving increased real-world external control arm (RW-ECA) use in health technology assessment submissions. However, concerns over residual confounding and unmeasured bias often…
Fuller S, Dent N, Ohly H et al. · 2026 · Preprint
Abstract Abstract Background: Infants under six months of age in low‑income countries (LICs) face high morbidity and mortality, driven by prematurity, low birthweight (LBW), malnutrition, infection, and environmental enteric dysfunction.…
Kanpittaya P, Nantanee R, Fakhruddin KS et al. · 2026 · International journal of oral and maxillofacial surgery
External apical root resorption (EARR) is a recognized adverse outcome of orthodontic treatment that may also be influenced by orthognathic surgery. However, the body of evidence on this combined effect is nascent and has not been mapped.…
Chen X, Qin X, Xu B et al. · 2026 · Preprint
Background: Social cognition research increasingly emphasizes cognitive processes in social contexts, with growing attention to socially shared retrieval-induced forgetting (SS-RIF). Behavioral evidence suggests that the mechanisms of…
Lebâcle C, Kassab D, Faix A et al. · 2026 · The French journal of urology
Objectives To provide a focused secondary synthesis and critical clinical interpretation of the AFU/SFMS evidence base on phytotherapies and complementary therapies for erectile dysfunction (ED). Evidence acquisition The parent AFU/SFMS…
Maisch P, Hamidi Madani M, Koziarz A et al. · 2026 · The Cochrane database of systematic reviews
Rationale Disease recurrence and progression remain major challenges in the treatment of non-muscle invasive bladder cancer (NMIBC). Blue light-enhanced transurethral resection of bladder cancer (TURBT) is an approach to improve staging…
Shao F, Han Z, Su Q et al. · 2026 · JMIR serious games
Background Serious games (SGs) have emerged as a promising tool in nursing education, providing interactive learning environments for clinical simulation, skill development, and feedback. These games enhance knowledge, clinical reasoning,…
Cai M, Lai W, Peng W et al. · 2026 · BMC oral health
Background Diabetes Mellitus (DM) is a global metabolic disorder affecting 537 million adults. Periodontitis stands as its sixth major complication and shares a bidirectional relationship with diabetes, whereby each condition exacerbates…
Angelucci F, Cerman J, Amlerova J et al. · 2026 · Degenerative neurological and neuromuscular disease
Spermidine is a naturally occurring polyamine involved in multiple cellular processes, including growth regulation, protein translation, and autophagy. Increasing attention has been devoted to its potential neuroprotective effects,…
Puli L, Kooijman L, Kanij T et al. · 2026 · Journal of medical Internet research
Background Routine financial activities are now conducted primarily through digital channels. Many such systems remain inaccessible to more than 2.2 billion people globally living with vision impairment, limiting independent financial…
Jahangeerbasha A, R HKV, R C · 2026 · Preprint
Abstract Background Peripheral intravenous catheters (PIVCs) are among the most frequently used vascular access devices in hospitalized patients and are essential for administering intravenous fluids, antibiotics, vasoactive medications,…
Sheldrick RC, Hooker JL, Davignon M et al. · 2026 · Academic pediatrics
Objectives We used real-world evidence to estimate the accuracy of autism screening questionnaires, including sensitivity, specificity, and predictive probabilities for positive results and for individual screening scores. Study design…
Zaher F, Ahrens J, Raucher-Chéné D et al. · 2026 · Bipolar disorders
Clinicians aspire to predict the emergence of Bipolar Disorder (BD) in a timely manner. To accomplish this, markers reflecting mental states that can be gathered non-invasively and at large scale are needed. Here, we systematically…
Weiss A · 2026 · Preprint
A recent paper (Minkov, 2026) claimed that great ape personality is not well-described by the five personality dimensions found in humans, those being Neuroticism, Extraversion, Openness to Experience, Agreeableness, and Conscientiousness.…
Nuss ZJ, DeYoung C, Gross D · 2026 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
ObjectiveTo evaluate current pharmacotherapeutic strategies for H3 K27M-mutant diffuse midline glioma (DMG), with emphasis on the clinical evidence for dordaviprone, its place in therapy, and its implications for oncology practice.Study…
Bellissimo J, Hall B, Hali K et al. · 2026 · The Journal of arthroplasty
Background Orthobiologic therapies such as platelet-rich plasma (PRP), bone marrow aspirate concentrate (BMAC), and hyaluronic acid (HA) are increasingly offered for orthopaedic conditions, but their online promotion may not accurately…
La Vignera S, Condorelli RA · 2026 · International journal of molecular sciences
Incretin-based therapies, particularly glucagon-like peptide-1 receptor agonists (GLP-1 RAs), have emerged as potentially promising therapeutic agents for improving ovarian function, especially in women with polycystic ovary syndrome…
Luo X, Wang B, Liu H et al. · 2026 · Integrative medicine research
Background Atopic dermatitis (AD) is a common chronic inflammatory skin disorder with substantial global burden. In some regions, Chinese medicine (CM) and integrated Chinese-Western medicine (ICWM) are widely used, but the overall…
Henriques JP, Weckwerth AVB, Santana ACP et al. · 2026 · Annales pharmaceutiques francaises
Objectives Diabetes mellitus and periodontal disease are highly prevalent chronic disorders linked by bidirectional inflammatory and oxidative pathways. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are emerging pharmacologic agents…
Shukkoor AA, Turgeon RD, De Vera MA et al. · 2026 · BMJ open
Objectives This study aimed to investigate the association and potential causal relationship between ischaemic stroke/transient ischaemic attack (TIA) and oral anticoagulant (OAC) adherence using Bradford Hill's criteria and to determine…