Negative / Null Result ReportMedicine
Zhao P, Zhao S, Huang C et al. · 2025 · Hematological oncology
Polatuzumab vedotin plus R-CHP (Pola-R-CHP) is approved as a new standard first-line therapy for diffuse large B-cell lymphoma (DLBCL) based on the POLARIX trial. However, real-world data on its efficacy and safety in unselected patients…
View details →DOI: 10.1002/hon.70017 Negative / Null Result ReportOpen accessMedicine
Reindl N, Seitz S, Schleier M et al. · 2025 · Pediatric surgery international
Purpose Postoperative scarring remains a major concern for patients and parents following repair of congenital abdominal wall defects. This study evaluated perceptions of postoperative scars in children after omphalocele or gastroschisis…
View details →DOI: 10.1007/s00383-025-06287-1 Negative / Null Result ReportMedicine
Thomas P, Kerrey B, Edmunds K et al. · 2024 · Pediatric emergency care
Background The lower clinical exposure of Pediatric Emergency Medicine (PEM) fellows to critical procedures may impede skill acquisition. We sought to determine the tracheal intubation learning curve of PEM fellows during training and…
View details →DOI: 10.1097/pec.0000000000003204 Negative / Null Result ReportOpen accessMedicine
Pelzer F, Leisge K, Kaczmarek C et al. · 2025 · Scientific reports
We often perform motor tasks in front of other people, and this may help or hinder our performances. Previous research mainly focused on changes in motor performance, and less is known about spectator influences on performance predictions.…
View details →DOI: 10.1038/s41598-025-18048-0 Negative / Null Result ReportOpen access
Moore E, Webb E, Sasaki R et al. · 2025 · Preprint
Numerous studies highlight alterations in motor cortical neurophysiology after mild traumatic brain injury (mTBI). In contrast, understanding of effects in cognitive brain areas, which potentially underpin more impactful effects of injury,…
View details →DOI: 10.1101/2025.05.22.655676 Negative / Null Result ReportOpen accessMedicine
Panzer S, Hofstetter N, Schreiber M et al. · 2026 · Experimental brain research
The present study examined if a daytime nap of 90 min can further improve skill memory afforded by observation and physical practice. Moreover, we determined if a 'nap' benefit was restricted to a particular representational form (spatial…
View details →DOI: 10.1007/s00221-026-07281-2 Negative / Null Result ReportMedicine
McNaughton DT, Mara P, Jones MP · 2024 · Australian health review : a publication of the Australian Hospital Association
Objective There is a need to undertake more proactive and in-depth analyses of general practice accreditation processes. Two areas that have been highlighted as areas of potential inconsistency are the self-assessment and surveyor…
View details →DOI: 10.1071/ah23235 Replication FailureOpen accessMedicine
Alevi KCC, Ravazi A, de Oliveira J et al. · 2025 · Scientific reports
The diversification of Rhodnius species has been primarily attributed to vicariance events. Phylogenomic studies have proposed various evolutionary hypotheses - such as incomplete lineage sorting, hybrid speciation, and introgression - to…
View details →DOI: 10.1038/s41598-025-29472-7 Failed Experiment ReportOpen accessMedicine
Srivastava S, Kharkar VR, More S et al. · 2024 · Journal of clinical and experimental dentistry
Background Absorbable gelatin sponges are able to reduce the incidence of post-extraction complications when soaked with antimicrobial agents. However, the drawbacks associated with the injudicious use of antibiotics warrant the need to…
View details →DOI: 10.4317/jced.61640 Replication FailureOpen accessMedicine
Tidblad L, Öberg Sysojev A, Delcoigne B et al. · 2025 · RMD open
Objective To examine whether obesity and/or overweight are independently associated with an increased risk of remission failure in patients with early rheumatoid arthritis (RA), treated with methotrexate as first disease-modifying…
View details →DOI: 10.1136/rmdopen-2025-005430 Replication FailureOpen accessMedicine
Medeiros CNA, Azevedo IG, Gomes Fernandes SG et al. · 2026 · PeerJ
Background Urinary incontinence (UI) is a common complaint among middle-aged and older women, associated with many negative impacts in health. The aim of this study was to analyze whether an association exists between UI and sarcopenic…
View details →DOI: 10.7717/peerj.20470 Negative / Null Result ReportOpen accessMedicine
Fowler TE, Bloomquist RF, James JN · 2025 · BMC oral health
Background The incidence of fascial space infections of the head and neck has long been suggested to correlate with weather patterns, though objective evidence is inconsistent, and a causative effect is difficult to prove. One issue in the…
View details →DOI: 10.1186/s12903-025-06621-y Negative / Null Result ReportOpen accessMedicine
Viskupič F, Wiltse DL · 2025 · PLOS global public health
It is possible that the negative attitudes toward COVID-19 vaccination developed by some people, such as self-identified Republicans, might spill over toward other vaccines. We conducted a survey experiment to investigate if mentioning…
View details →DOI: 10.1371/journal.pgph.0005180 Negative / Null Result ReportMedicine
Meade MJ, Jensen S, Ju X et al. · 2024 · International orthodontics
Objective The aim of the present study was to evaluate the quality and readability of content contained within clear aligner therapy (CAT) informed consent forms. Methods CAT informed consent forms were identified via an online search. The…
View details →DOI: 10.1016/j.ortho.2024.100873 Negative / Null Result ReportOpen accessMedicine
Chhaya D, Gress M, Raja A et al. · 2024 · International journal of environmental research and public health
The objective of this study is to investigate the potential mutagenic effects of the exposure of mice to aerosols produced from the component liquids of an electronic nicotine delivery system (ENDS). The use of electronic cigarettes…
View details →DOI: 10.3390/ijerph21121693 Negative / Null Result Report
Xu L, Yu D, Li F et al. · 2024 · Preprint
Abstract Objective To determine the efficacy and tolerability of Anlotinib plus temozolomide (TMZ) as a first-line treatment for recurrent malignant glioma (rMG). Methods A total of 30 eligible patients who relapsed from the standard…
View details →DOI: 10.21203/rs.3.rs-4373518/v1 Negative / Null Result ReportOpen accessMedicine
Maier F, Luttenberger I, Dreisoerner A et al. · 2026 · Stress and health : journal of the International Society for the Investigation of Stress
Chronic stress has well-documented adverse effects on physical and psychological health. Beyond contributing to the development of fatigue, its impact is intensified by social stressors such as loneliness, making the development of…
View details →DOI: 10.1002/smi.70145 Negative / Null Result Report
Turner TJ, Brun P, Gruber R et al. · 2024 · Preprint
Tolebrutinib is a covalent BTK inhibitor designed and selected for potency and CNS exposure to optimize impact on BTK-dependent signaling in CNS-resident cells. We applied a translational approach to evaluate three BTK inhibitors in Phase…
View details →DOI: 10.1101/2024.03.25.586667 Negative / Null Result ReportOpen accessMedicine
Al-Khalaifah H, Al-Nasser A, Al-Surrayai T · 2025 · Life (Basel, Switzerland)
There is growing interest in adding marine algae to poultry feed rations. The aim of the present study is to examine the effect of various inclusions of Sargassum sp., Gracilaria sp., and Spirulina sp. on productive performance, serum…
View details →DOI: 10.3390/life15040670 Negative / Null Result ReportOpen accessMedicine
Zamora Veliz HY, Paredes Cabanillas RY, Gomez Trejo JE et al. · 2025 · Cureus
Introduction Intestinal anastomotic leakage is a serious postoperative complication associated with high morbidity and mortality. Although acute-phase reactants such as procalcitonin (PCT) and CRP have been proposed as early biomarkers,…
View details →DOI: 10.7759/cureus.88190 Negative / Null Result ReportOpen accessMedicine
Halačová M, Mieresová M, Kubele J et al. · 2026 · Pharmacological reports : PR
BACKGROUND: Beta-lactams are the cornerstone of therapy for the treatment of the most serious infections in the intensive care unit (ICU) setting. However, individualization of dosing remains challenging because pharmacokinetics are highly…
View details →DOI: 10.1007/s43440-026-00836-8 Negative / Null Result ReportOpen accessMedicine
Dumont JR, Sheppard PAS, Fodor C et al. · 2025 · Genes, brain, and behavior
Alzheimer's disease is a debilitating neurodegenerative condition characterized by amyloid beta plaques and tau neurofibrillary tangles, which leads to progressive cognitive decline. Several new mouse models of fast amyloid deposition have…
View details →DOI: 10.1111/gbb.70024 Negative / Null Result ReportMedicine
Langevin P, Frémont P, Fait P et al. · 2024 · Disability and rehabilitation
Purpose The objective of this study was to compare the effects of an in-clinic cervicovestibular rehabilitation program (education, home exercises, manual techniques, sub-symptom threshold aerobic exercise [STAE] program) to a similar…
View details →DOI: 10.1080/09638288.2023.2236016 Negative / Null Result ReportMedicine
Schleifenbaum L, Stern J, Driebe JC et al. · 2024 · Hormones and behavior
Previous research on the endogenous effects of ovarian hormones on motivational states in women has focused on sexual motivation. The Motivational Priority Shifts Hypothesis has a broader scope. It predicts a shift from somatic to…
View details →DOI: 10.1016/j.yhbeh.2024.105542 Negative / Null Result ReportMedicine
Fumagalli D, Sonik R, De Vitis LA et al. · 2024 · Gynecologic oncology
Background Advanced epithelial ovarian cancer (OC) patients often present with malnutrition; however, the ideal nutritional evaluation tool is unclear. We aimed to evaluate the role of preoperative albumin, Prognostic Nutritional Index…
View details →DOI: 10.1016/j.ygyno.2024.06.021 Negative / Null Result ReportOpen accessMedicine
Figueiredo RR, de Azevedo AA, Figueiredo GMR et al. · 2026 · Brazilian journal of otorhinolaryngology
Objectives COVID-19 is a respiratory disease caused by the coronavirus SARS-CoV-2. Previous studies reported cases of tinnitus following COVID infection, most of them mild and with similar characteristics to other forms of tinnitus. Our…
View details →DOI: 10.1016/j.bjorl.2026.101857 Negative / Null Result ReportMedicine
Bello RJ, Palleiko BA, Kennedy K et al. · 2024 · Surgical oncology
Background Pain management following mastectomy is a significant challenge often requiring opioids. Nonopioid pain management utilizing nerve blocks has been shown in other fields to reduce postoperative opioid use and may be effective for…
View details →DOI: 10.1016/j.suronc.2024.102055 Negative / Null Result ReportOpen accessMedicine
Pan L, Kaku Y, Tolentino JE et al. · 2025 · Frontiers in microbiology
In the 21st century, three severe human coronavirus infections have occurred. One of them is the Middle East respiratory syndrome coronavirus (MERS-CoV), a merbecovirus belonging to the family Coronaviridae , is a human pathogenic…
View details →DOI: 10.3389/fmicb.2025.1593095 Negative / Null Result ReportOpen accessMedicine
Khan M, Yousaf H, Naqqash M et al. · 2025 · Cureus
Introduction There is limited local data comparing the outcomes of core decompression and fibular strut grafting in early-stage avascular necrosis (AVN) of the hip. International findings may not be directly applicable due to…
View details →DOI: 10.7759/cureus.92733 Negative / Null Result ReportOpen accessMedicine
Yaşar NF, Badak B, Salış M et al. · 2024 · Revista da Associacao Medica Brasileira (1992)
Objective Endogenous melatonin is produced from tryptophan which is an essential amino acid. Besides its role in the regulation of sleep patterns, melatonin has anti-inflammatory effects. In this case-control study, we aimed to compare…
View details →DOI: 10.1590/1806-9282.20230826 