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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21707 results · page 267 of 724

Negative / Null Result Report

Immersive Virtual Reality in Undergraduate Critical Care Nursing Education: A Pragmatic Three-Cohort Quasi-Experimental Evaluation of Perceived Simulation Effectiveness and Clinical Learning Needs

Ismaile S, Alhosban F, Shajrawi A et al. · 2026 · Preprint

Abstract Background Preparing undergraduate nurses for high-acuity practice requires educational approaches that allow safe rehearsal of complex clinical situations, yet evidence from routine programme delivery remains mixed when immersive…

View details →DOI: 10.21203/rs.3.rs-9187827/v1
Negative / Null Result ReportMedicine

Effect of Remimazolam or Propofol Combined With Esketamine on Anesthesia and Early Perioperative Neurocognitive Disorders in Patients Undergoing Thoracoscopic Partial Lung Resection: A Randomized Clinical Trial.

Yuan W, Liang X, Zhang R et al. · 2026 · Clinical therapeutics

Purpose This study aimed to evaluate the effects of remimazolam in conjunction with esketamine on anesthesia and the incidence of early perioperative neurocognitive disorders (PNDs) in patients undergoing thoracoscopic partial lung…

View details →DOI: 10.1016/j.clinthera.2026.02.015
Negative / Null Result Report

Safety and short-term outcomes during the introduction of retroperitoneal single-port robot-assisted radical prostatectomy: a single-surgeon comparison with transperitoneal multiport radical prostatectomy in a Japanese population

Hattori S, Shimizu K, Kotorii R et al. · 2026 · Preprint

Abstract Purpose. To evaluate the safety and feasibility of introducing retroperitoneal single-port robot-assisted radical prostatectomy (SP-RARP) by comparing a single surgeon’s initial 50 cases with 50 recent transperitoneal multiport…

View details →DOI: 10.21203/rs.3.rs-9990410/v1
Negative / Null Result ReportMedicine

Challenge Under Pressure Contextual Interference or Differential Learning.

Taghizadeh H, Parvizi MJ, Roostaei A et al. · 2026 · Research quarterly for exercise and sport

This study compared the effects of blocked practice, random practice (contextual interference), and differential learning on acquisition, retention, and performance under psychological pressure of a basketball jump shot in novice…

View details →DOI: 10.1080/02701367.2026.2686249
Negative / Null Result Report

Evaluating the sensitivity of heart rate variability fractal correlation properties to training load variations: Implications for monitoring training readiness and durability

van Rassel CR, Rummel M, MacInnis MJ · 2026 · Preprint

This study examined the utility of HRV detrended fluctuation analysis alpha-1 (DFAα1) to assess readiness-to-train and exercise durability under varying acute training loads. Nineteen trained cyclists completed two 20-minute time-trials…

View details →DOI: 10.64898/2026.05.27.26354281
Negative / Null Result Report

The KangDuo Robotic System, Da Vinci Robotic System, and Laparoscopic Surgery for Endometrial Cancer: A Retrospective Study Based on Real-World Data

Huang W, Jiang L, Wang H et al. · 2026 · Preprint

Abstract Background With advances in minimally invasive surgery, endometrial cancer treatment has evolved from laparotomy to laparoscopic (LS) and robotic techniques. However, outcomes such as surgical trauma, recovery, and cost vary…

View details →DOI: 10.21203/rs.3.rs-9654946/v1
Negative / Null Result ReportMedicine

Evaluation of Osteomeatal Complex Anatomical Variations, Pathologies and Nasal Cavity Volume in Patients with Cleft Lip and Palate.

Cebeci T, Polat Akmansoy B · 2026 · The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

ObjectiveTo compare osteomeatal complex (OMC) anatomical variations and nasal cavity airway volume between individuals with cleft lip and palate (CLP) and healthy controls using cone beam computed tomography (CBCT).DesignRetrospective,…

View details →DOI: 10.1177/10556656261458450
Negative / Null Result ReportMedicine

The use of partially slatted floor designs as an alternative to littered systems in broiler chickens. II. The effects on welfare and behavioral traits.

Çavdarcı H, Sarıca M, Erensoy K et al. · 2026 · Tropical animal health and production

This study investigated the effects of different flooring designs on the welfare and behavioral traits in fast-growing broilers. A total of 600 day-old Ross-308 chickens were randomly allocated to five treatment groups: fully littered…

View details →DOI: 10.1007/s11250-026-05149-9
Negative / Null Result ReportMedicine

Sublethal effects and bioaccumulation of "smart" anti-corrosion nanoadditives spiked in sediment in the ragworm Hediste diversicolor.

Bruni M, Perina F, Figueiredo J et al. · 2026 · Aquatic toxicology (Amsterdam, Netherlands)

Metallic corrosion poses an economic problem worldwide and is often mitigated by adding corrosion inhibitors (CIs) to protective coatings. Conventional CIs, such as 2-mercaptobenzothiazole (MBT) and benzotriazole (BTA), exhibit toxicity to…

View details →DOI: 10.1016/j.aquatox.2026.107912
Negative / Null Result ReportMedicine

The Effect of Concomitant Hysterectomy Route on Robotic Sacrocolpopexy Outcomes.

Swallow C, Imamoglu M, Imamoglu AG et al. · 2025 · Urogynecology (Philadelphia, Pa.)

Importance Sacrocolpopexy is essential in the surgical management of advanced pelvic organ prolapse, and selecting the appropriate route for concomitant hysterectomy is critical. Objectives The aim of this study was to evaluate the effect…

View details →DOI: 10.1097/spv.0000000000001659
Negative / Null Result ReportOpen accessMedicine

Ductus Arteriosus Morphology in Pulmonary Atresia With Ventricular Septal Defect: A Retrospective Case Series Comparing Echocardiography and Digital Subtraction Angiography.

Quan TT, Nguyen HM, Nguyen HT et al. · 2026 · Cureus

Objective This study aims to describe ductus arteriosus (DA) morphology in patients with pulmonary atresia with ventricular septal defect (PA-VSD) and to assess exploratory paired differences between echocardiography and digital…

View details →DOI: 10.7759/cureus.108765
Negative / Null Result ReportMedicine

Embryo Euploidy Rates and Reproductive Outcomes Following Ethanol Sclerotherapy, Laparoscopic Cystectomy, or No Intervention for Ovarian Endometriomas Prior to IVF with PGT-A: A Retrospective Cohort Study.

Goc G, Sukur YE · 2026 · Journal of minimally invasive gynecology

Study objective To compare embryo euploidy rates and reproductive outcomes among women with ovarian endometriomas who underwent ethanol sclerotherapy (EST), laparoscopic cystectomy, or expectant management prior to in vitro fertilization…

View details →DOI: 10.1016/j.jmig.2026.06.010
Negative / Null Result ReportMedicine

Appendiceal location in Japanese children with acute appendicitis: pelvic predominance and diagnostic and operative implications.

Koga S, Noguchi S, Kondo T · 2026 · Pediatric surgery international

Purpose Appendiceal location may affect the diagnosis and surgical management of acute appendicitis. However, pediatric-specific data remain limited. This study evaluated appendiceal location in Japanese children with acute appendicitis…

View details →DOI: 10.1007/s00383-026-06498-0
Negative / Null Result Report

Impact of Postoperative Silodosin on Delayed Stone-Free Status After Retrograde Intrarenal Surgery: Emphasis on Patients with Residual Fragments

Akdag A, Aktas E, Kutlu A et al. · 2026 · Preprint

Abstract Purpose: Residual fragments after retrograde intrarenal surgery (RIRS) may compromise delayed stone-free (SF) status and increase the likelihood of secondary intervention. This study evaluated the association between postoperative…

View details →DOI: 10.21203/rs.3.rs-9849277/v1
Negative / Null Result ReportMedicine

First head-to-head comparison of allograft repair, direct neurorrhaphy and non-surgical management for iatrogenic trigeminal nerve injury: a prospective multicentre cohort study with doubly robust analysis.

Van der Cruyssen F, Willaert R, Palla B et al. · 2026 · International journal of oral and maxillofacial surgery

Trigeminal nerve injuries severely degrade quality of life, yet comparative effectiveness evidence for existing treatments is scarce. The authors prospectively followed 153 adults with iatrogenic lingual or inferior alveolar nerve injuries…

View details →DOI: 10.1016/j.ijom.2026.06.014
Negative / Null Result ReportMedicine

Changes in Gait Kinematics with Continuous Intrathecal Baclofen Infusion for Spasticity After Acquired Brain Injury: A Comparison of Implanted and Non-Implanted Cohorts.

Chow JW, Yablon SA, Stokic DS · 2026 · NeuroRehabilitation

BackgroundAlthough several studies have examined gait changes associated with continuous intrathecal baclofen (CITB) infusion for spasticity in ambulatory patients with acquired brain injury (ABI), none has included a control…

View details →DOI: 10.1177/10538135261459634
Negative / Null Result ReportOpen accessMedicine

Mid-term outcomes and hemodynamic performance of Edwards 19-mm-labeled aortic valve bioprostheses: a single-center retrospective study.

Gyoten T, Akatsu T, Kuroda T et al. · 2026 · Journal of cardiothoracic surgery

Background This study aimed to evaluate clinical outcomes after surgical aortic valve replacement with third-generation Edwards (Edwards Lifesciences, Irvine, CA, USA) 19-mm-labeled aortic valve bioprostheses, including a rapid-deployment…

View details →DOI: 10.1186/s13019-026-04158-x
Negative / Null Result ReportMedicine

Characteristics of the Tongue Coating Microbiome and Its Subtype Differences in Patients with Inflammatory Bowel Disease.

Shen J, Yu X, Xu J et al. · 2026 · Microorganisms

Inflammatory bowel disease (IBD) is associated with microbial dysbiosis, yet subtype-specific alterations in the tongue-coating microbiome remain insufficiently characterized. In this cross-sectional study, tongue-coating samples from 158…

View details →DOI: 10.3390/microorganisms14061381
Negative / Null Result ReportMedicine

Evaluation of parotid and submandibular salivary glands by ultrasonography in patients using antidepressants: a case control study.

Tanrıverdi S, Yeşiltepe S · 2026 · BMC oral health

Background Antidepressants are widely prescribed group of medications frequently associated with xerostomia. Although alterations in salivary flow among antidepressant users have been extensively investigated, there is a paucity of data…

View details →DOI: 10.1186/s12903-026-08892-5
Negative / Null Result ReportMedicine

Comparison of Post-Landing Stability During Basketball Jump Shots Under Real and Virtual Defensive Pressure.

Sun Y, Lee J, Wen X et al. · 2026 · Research quarterly for exercise and sport

The basketball jump shot is a fundamental skill in competitive play, and defensive pressure has been shown to influence movement execution and post-landing control. This study investigated post-landing stability during basketball jump…

View details →DOI: 10.1080/02701367.2026.2665730
Replication FailureMedicine

Diagnostic value of inguinal ultrasound for predicting histological lymph node status in vulvar cancer.

Hartmann S, Wenk N, Mann E et al. · 2026 · Ultraschall in der Medizin (Stuttgart, Germany : 1980)

Purpose As part of the pretherapeutic diagnostic workup for vulvar cancer, the inguinal lymph node status should be assessed. The diagnostic value of structured inguinal sonography for predicting the histological lymph node status in…

View details →DOI: 10.1055/a-2830-7606
Replication FailureMedicine

HPV status fully mediates sex-related survival differences in oropharyngeal cancer: a population-based analysis with formal interaction testing.

Hoenle A, Rickert D, Steinhart H et al. · 2026 · The Journal of laryngology and otology

Objectives. To determine whether sex independently predicts survival in oropharyngeal squamous cell carcinoma and whether human papillomavirus status mediates apparent sex-related survival differences at the population level. Methods.…

View details →DOI: 10.1017/s002221512610512x