Negative / Null Result ReportMedicine
Björnsson O, Geirsson G, Leifsson ÁS et al. · 2026 · Scandinavian journal of urology
Introduction Transurethral resection of bladder tumor (TURBT) is the standard treatment for non-muscle-invasive bladder cancer (NMIBC), but early recurrences remain frequent. The objective of this study was to standardize TURBT management…
View details →DOI: 10.2340/sju.v61.45711 Negative / Null Result ReportMedicine
Mauter F, Anton M, van Engen R et al. · 2026 · Physics in medicine and biology
Objective. Digital mammography (DM) and dual-energy contrast-enhanced mammography (CEM) use the same anti-scatter grid, despite their differences in x-ray spectra. This study investigated grid performance under clinically relevant…
View details →DOI: 10.1088/1361-6560/ae2c39 Negative / Null Result ReportMedicine
Szarpak L, Al-Jeabory M, Pecold J et al. · 2026 · The aging male : the official journal of the International Society for the Study of the Aging Male
Introduction Testosterone replacement therapy (TRT) is increasingly prescribed to older men with symptomatic testosterone deficiency, yet the balance of musculoskeletal benefits and harms remains uncertain. Objectives To synthesise current…
View details →DOI: 10.1080/13685538.2026.2655544 Replication FailureMedicine
Takeda Y, Nakai T, Okamoto T et al. · 2026 · The Journal of arthroplasty
Background Mirogabalin, a selective α2δ-1 ligand, has been proposed to exhibit potent analgesic effects with fewer central nervous system (CNS) side effects than prior gabapentinoids. Its effectiveness for acute postoperative pain after…
View details →DOI: 10.1016/j.arth.2026.03.095 Negative / Null Result ReportMedicine
Carnevali A, Chisari D, Mancini A et al. · 2026 · Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
Introduction Inferior retinal detachment (I-RD) complicated by proliferative vitreoretinopathy (PVR) is challenging to treat and prone to recurrence (retinal detachment recurrence [RDR]). Heavy silicone oil (HSO) tamponades such as…
View details →DOI: 10.1159/000551398 Negative / Null Result ReportMedicine
Khera P, Jain S, Khurana S et al. · 2026 · European journal of pediatrics
Surfactant replacement therapy improves outcomes in preterm neonates with respiratory distress syndrome (RDS). While the less invasive surfactant administration (LISA) technique offers advantages over intubate-surfactant-extubate (INSURE),…
View details →DOI: 10.1007/s00431-026-06904-8 Replication FailureMedicine
Magno Serrano P, Barros P, Dores M et al. · 2026 · Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
Introduction Antibiotic resistance represents a major public health problem driven by inappropriate antimicrobial use. Cystoscopy is a common urological procedure associated with a low risk of urinary tract infection (UTI), and the role of…
View details →DOI: 10.4081/aiua.2026.14883 Replication FailureMedicine
Oreskovic NM, Erwin AE, Allon ZA et al. · 2026 · The American journal of managed care
Objectives Office-based care coordination programs are increasingly utilizing social work-trained care coordinators to manage high-cost, high-need (HCHN) patients with increased psychosocial risk, including patients covered by Medicaid.…
View details →DOI: 10.37765/ajmc.2026.89922 Replication FailureMedicine
Mølhave M, Olsen ZL, Svanesøe S et al. · 2025 · Acta oto-laryngologica
Background Tracheostomy is widely used in critically ill patients, yet limited clinical data exist from Danish ENT departments. Aims/objectives To describe clinical outcomes and perioperative care in patients undergoing tracheostomy at a…
View details →DOI: 10.1080/00016489.2025.2561917 Replication FailureMedicine
Bhardwaj A, Jain A, Jain N et al. · 2026 · Indian pediatrics
Objective To evaluate whether epinephrine nebulization, when used in addition to standard care, reduces extubation failure (EF) in term and preterm neonates. Methods A parallel, randomized controlled superiority trial was conducted in a…
View details →DOI: 10.1007/s13312-026-00306-7 Negative / Null Result ReportMedicine
Chlebowski RT, Rapp S, Aragaki AK et al. · 2026 · Menopause (New York, N.Y.)
Objectives In the Women's Health Initiative (WHI) Dietary Modification (DM) randomized trial, the dietary intervention significantly reduced breast cancer mortality and, in a subgroup of women 65 years old or above, significantly lowered…
View details →DOI: 10.1097/gme.0000000000002808 Negative / Null Result ReportMedicine
Rozier R, Loiseleur A, Ciais C et al. · 2026 · Regional anesthesia and pain medicine
Background Total hip arthroplasty (THA) frequently causes postoperative pain, hindering recovery and prolonging hospital stays. While multimodal analgesia aims to minimize opioid use and enhance outcomes, the optimal regional anesthesia…
View details →DOI: 10.1136/rapm-2024-106247 Negative / Null Result ReportMedicine
Yang M, Chen Y, Yang L et al. · 2026 · International journal of biological macromolecules
Plants face significant threats from pathogens while chemical pesticides remain the primary method for disease control. However, excessive use of chemical pesticides has led to increased pathogen resistance and environmental hazards,…
View details →DOI: 10.1016/j.ijbiomac.2026.152953 Negative / Null Result Report
Lima VHA, Reis EFd, Devilla IA et al. · 2026 · Preprint
Most studies in the field of application technology have focused on the interaction between adjuvants and agrochemicals, highlighting the need for further research to evaluate the behavior of adjuvants in association with other classes of…
View details →DOI: 10.20944/preprints202604.0247.v1 Negative / Null Result ReportMedicine
Benade F, Jülke S, Schwelm A et al. · 2026 · Journal of experimental botany
The clubroot pathogen Plasmodiophora brassicae has an effector protein that can methylate the plant defense compound salicylic acid (SA), and the protein sequence is highly conserved in different isolates worldwide. Sequencing the…
View details →DOI: 10.1093/jxb/eraf548 Negative / Null Result Report
Richardson M, Masurkar RA, Tyson L et al. · 2026 · Preprint
Intrusive memories are a central feature of posttraumatic stress disorder (PTSD) and are thought to emerge through associative learning processes during trauma. Cognitive models propose that conditioned stimuli (CSs) occurring in close…
View details →DOI: 10.31234/osf.io/26zry_v1 Negative / Null Result ReportMedicine
Lam AD, Foreman SR, Davidson SJ et al. · 2026 · The Journal of arthroplasty
Background The growing expansion of outpatient total knee arthroplasty (TKA) and emphasis on multimodal pain control to reduce opioid consumption are essential in optimizing perioperative care. This study aimed to assess postoperative…
View details →DOI: 10.1016/j.arth.2026.03.033 Negative / Null Result ReportMedicine
Mans-Gallart N, Carlhäll S, Hildebrand E et al. · 2026 · American journal of obstetrics and gynecology
Background Preeclampsia is a substantial cause of maternal and perinatal morbimortality, with complications becoming more severe the earlier it manifests during pregnancy. The Fetal Medicine Foundation has developed a method that combines…
View details →DOI: 10.1016/j.ajog.2025.10.028 Negative / Null Result ReportMedicine
Biddlestone M, Green R, Toribio-Flórez D et al. · 2025 · British journal of psychology (London, England : 1953)
Prebunking can be used to pre-emptively refute conspiracy narratives. We developed a new approach to prebunking - fighting fire with fire - which introduces a plausible 'meta-conspiracy' suggesting that conspiracy theories are deliberately…
View details →DOI: 10.1111/bjop.70023 Negative / Null Result Report
Snape D, Wainwright B, Parsons IT et al. · 2026 · Preprint
Short-term heat acclimation (HA) induces cardiovascular and fluid-regulatory adaptations, but it’s impact on markers of renal tubular injury and acute kidney injury risk (AKI) during exercise-heat stress remains unclear. Fourteen healthy…
View details →DOI: 10.64898/2026.03.06.710014 Negative / Null Result ReportMedicine
Jourquin S, Lowie T, Clinquart J et al. · 2026 · Journal of dairy science
This randomized clinical trial evaluated the effect of upon-arrival intranasal vaccination against bovine coronavirus (BCoV) on pneumonia risk in a beef-on-dairy veal production system. Secondary objectives were to assess the effect…
View details →DOI: 10.3168/jds.2026-28339 Negative / Null Result ReportMedicine
Ang D, Nathens A, Nayduch D et al. · 2026 · Annals of surgery
Objectives To evaluate whether surgical stabilization of rib fractures (SSRF) improves acute and patient-centered outcomes in adults with clinically significant rib fractures. Summary of background data Rib fractures occur in up to 40% of…
View details →DOI: 10.1097/sla.0000000000007053 Negative / Null Result ReportMedicine
Uehara T, Itoh H, Abe H et al. · 2026 · Psychopharmacology
Rationale Apocynin-tandospirone derivatives (ATDs) have recently been shown to ameliorate methamphetamine (MAP)-induced behavioral abnormalities when administered chronically, presumably through antioxidant and interneuron-related…
View details →DOI: 10.1007/s00213-026-07040-9 Negative / Null Result ReportMedicine
Marzo-Escartín B, Villamarín-Melio M, Márquez-Algaba E et al. · 2026 · Surgical infections
Background Peristomal infection (PI) is the most frequent complication following percutaneous gastrostomy, and the increase of multi-drug-resistant (MDR) bacteria poses a therapeutic challenge. We evaluated whether targeted antimicrobial…
View details →DOI: 10.1177/10962964261438723 Negative / Null Result ReportMedicine
Rana CJ, Bakshi SG, Tarhane S et al. · 2026 · Indian journal of surgical oncology
Distract trial In the post-operative period, analgesics are complemented with non-pharmacological methods (NPM). However, the evidence is limited. Objectives Randomised control trial aimed to determine the effectiveness of NPMs of pain…
View details →DOI: 10.1007/s13193-026-02583-x Negative / Null Result ReportMedicine
Porter A, Nguyen J, Peng Y et al. · 2026 · The American journal of sports medicine
Background Intra-articular triamcinolone acetonide (TA) injections are commonly used to manage joint synovitis despite reports that they accelerate cartilage degeneration. Previous studies found that TA minimally affected bovine cartilage,…
View details →DOI: 10.1177/03635465261439028 Negative / Null Result ReportMedicine
Van de Perre E, Tielemans C, De Clerck D et al. · 2026 · Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Background and hypothesis Hyperoxaluria is an important risk factor for kidney stone formation. Currently available treatment options for idiopathic hyperoxaluria have limited efficacy and are difficult to maintain in the long-term.…
View details →DOI: 10.1093/ndt/gfag103 Negative / Null Result ReportMedicine
Islam IS, McGetrick ME, Leon RL et al. · 2026 · The Annals of thoracic surgery
Background We implemented a preoperative screening brain magnetic resonance imaging (MRI) protocol for neonates undergoing cardiac surgery. The intent was to identify unrecognized central nervous system (CNS) injury that might alter the…
View details →DOI: 10.1016/j.athoracsur.2026.03.011 Negative / Null Result ReportMedicine
Tian Q, Tian B, Li K et al. · 2026 · Neurosurgical review
The effectiveness of surgical intervention for hydrocephalus in patients with prolonged disorders of consciousness (pDoC) remains controversial. To investigate the impact of ventriculoperitoneal shunt (VPS) on secondary hydrocephalus…
View details →DOI: 10.1007/s10143-026-04211-2 Negative / Null Result ReportMedicine
Rasmussen JJ, Bisgaard J, Hønge JL et al. · 2026 · Journal of cardiothoracic and vascular anesthesia
Objectives Managing pain after median sternotomy is a clinical challenge of balancing adequate pain relief with avoidance of excessive opioid consumption. While regional anesthesia techniques are increasingly recommended and applied in…
View details →DOI: 10.1053/j.jvca.2026.03.042 