Perioperative Administration of Mirogabalin for Postoperative Pain Management Following Total Hip Arthroplasty: A Randomized Controlled Trial.
Takeda Y; Nakai T; Okamoto T; Matsumoto S; Fukunishi S; Tachibana T · 2026 · The Journal of arthroplasty
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
Background Mirogabalin, a selective α2δ-1 ligand, has been proposed to exhibit potent analgesic effects with fewer central nervous system (CNS) side effects than prior gabapentinoids. Its effectiveness for acute postoperative pain after…
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Metadata source: Europe PMC · DOI 10.1016/j.arth.2026.03.095