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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21707 results · page 234 of 724

Negative / Null Result ReportOpen accessComputer Science

Visual Matters: Connecting Aesthetic Appeal and Production Quality of Photos, Infographics and Data Visualizations to Credibility of Social Media Posts

Salman Khawar, Yingdan Lu, Yilang Peng et al. · 2026 · arXiv

The rapid proliferation of visual content raises fundamental questions about how different visual formats and features shape perceived credibility. Drawing on processing fluency theory, this research examines how visuals shape credibility judgments. We focus on three popular formats-photos, infographics, and data visualizations-comparing them to text-only posts, and test how two visual features, aesthetic appeal and production quality, influence credibility through processing fluency as a mediating mechanism. Through a preregistered experiment with 1200 US participants, we found that visual po

Negative / Null Result ReportOpen accessPhysics

A first-principles investigation of band inversion in topologically nontrivial Na2AgX (X= As, Sb and Bi) full Heusler compounds

A. Boughena, S. Benalia, O. Cheref et al. · 2021 · arXiv

Topological nontrivial nature are the latest phases to be discovered in condensed matter physics with insulating bulk band gaps and topologically protected metallic surface states; they are one of the current hot topics because of their unique properties and potential applications. In this paper, we have highlighted a first-principles study of the structural stability and electronic behavior of the Na${}_{2}$AgX (X= As, Sb and Bi) full Heusler compounds, using the Full-Potential Linear Muffin-Tin Orbital (FP-LMTO) method. We have originated that the Hg${}_{2}$CuTi structure is appropriate in a

Negative / Null Result ReportMedicine

Flash glucose monitoring addition to self-monitoring of blood glucose and perinatal outcomes in gestational diabetes: a randomized controlled trial.

Zorko K, Munda A, Janež A et al. · 2026 · American journal of obstetrics and gynecology

Background Self-monitoring of blood glucose represents the standard for glycemic monitoring in gestational diabetes mellitus, while the role of continuous glucose monitoring remains uncertain. Objective To assess whether adjunctive flash…

View details →DOI: 10.1016/j.ajog.2026.03.030
Negative / Null Result ReportMedicine

Durability and mechanistic performance of aztreonam/avibactam versus aztreonam plus ceftazidime/avibactam against Stenotrophomonas maltophilia complex.

Kunz Coyne AJ, Gray R, Gonnabathula P et al. · 2026 · The Journal of antimicrobial chemotherapy

Background Stenotrophomonas maltophilia complex infections are difficult to treat because of intrinsic resistance mediated by the L1 metallo-β-lactamase and L2 serine β-lactamase. Although aztreonam/avibactam is clinically available,…

View details →DOI: 10.1093/jac/dkag177
Negative / Null Result ReportMedicine

Switching anti-VEGF agents does not improve visual outcomes in branch retinal vein occlusion-related macular edema.

Peretz-Kahlon M, Wood K, Harris A et al. · 2026 · Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

BACKGROUND: Branch retinal vein occlusion (BRVO) frequently results in macular edema (ME), impairing visual acuity (VA). Intravitreal anti-vascular endothelial growth factor (VEGF) injections are standard first-line therapy but the benefit…

View details →DOI: 10.1007/s00417-026-07227-y
Negative / Null Result ReportMedicine

Endogenous Theta as a Function of Task Load and Working Memory Capacity: Revisiting the Role of Slower Frequencies in Theta-Gamma Coupling.

Tortajada M, Rodríguez-Larios J, Martínez-Pérez V et al. · 2026 · Journal of cognitive neuroscience

Recent findings have shown the influential role of theta-gamma cross-frequency coupling in the maintenance of items in working memory (WM). Specifically, it has been proposed that individual items are represented within gamma oscillations…

View details →DOI: 10.1162/jocn.a.2594
Negative / Null Result ReportMedicine

Real-World Data on Treatment Compliance and Visual Outcomes Between Patients With Diabetic Macular Edema or Retinal Vein Occlusion Receiving Antivascular Endothelial Growth Factor Injections or Intravitreal Corticosteroid Implants.

Kim SB, Lopez A, Gu X et al. · 2026 · Journal of vitreoretinal diseases

Purpose: To evaluate real-world differences in treatment frequency, appointment compliance, and visual outcomes among patients with DME or RVO whose eyes either remained on antivascular endothelial growth factor (anti-VEGF) therapy or were…

View details →DOI: 10.1177/24741264261438457
Negative / Null Result ReportMedicine

Testing the efficacy of a defocusing intervention to improve affective forecasting accuracy in younger and older adults.

Sobel Misieczko M, Barber SJ · 2026 · Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition

Affective forecasting, the process of predicting future feelings, is key for decision-making, but prone to errors. Prior research suggests that age differences in forecasting accuracy vary by event valence such that older adults tend to be…

View details →DOI: 10.1080/13825585.2026.2642773
Negative / Null Result Report

Acute profound thrombocytopenia associated with glycoprotein IIb/IIIa receptor inhibitor after percutaneous coronary intervention: therapy insights from a single center 6-year experience

Wu Y, Feng K, Liu L et al. · 2026 · Preprint

Abstract Background Acute profound thrombocytopenia is an infrequent, but potentially serious, even fatal complication associated with intravenous glycoprotein IIb/IIIa receptor inhibitors (GPI), which are widely used in acute coronary…

View details →DOI: 10.21203/rs.3.rs-9038136/v1
Negative / Null Result ReportMedicine

Effects of Dry-Land Versus In-Water Resistance Priming Exercise on Performance Parameters of Young Female Water Polo Players.

Brisola GMP, da Cruz AL, Belorio LGDS et al. · 2026 · Journal of strength and conditioning research

Abstract Brisola, GMP, da Cruz, AL, Belorio, LGdS, Grossi, JP, De Poli, RAB, Zagatto, AM, Esco, MR, and Mendes, OdC. Effects of dry-land versus in-water resistance priming exercise on performance parameters of young female water polo…

View details →DOI: 10.1519/jsc.0000000000005461
Negative / Null Result ReportMedicine

A single autoregressive integrated moving average with exogenous variable outperforms ensembles of autoregressive models for forecasting influenza hospitalizations in the contiguous United States.

Arraes Rocha Felix V, Rohani P, Drake JM · 2026 · Journal of the Royal Society, Interface

Infectious disease forecasting is important to public health decision-making, particularly for mitigating the burden of seasonal influenza. We propose and evaluate comprehensive autoregressive modelling approaches (autoregressive…

View details →DOI: 10.1098/rsif.2025.0813
Negative / Null Result ReportMedicine

<i>S</i>-Methyl cysteine sulfoxide: its effects on cardiometabolic outcomes in high-fat fed C57BL/6 mice and relevance to human health.

Hill CR, Balmer L, Abbiss H et al. · 2026 · Food & function

S -Methyl cysteine sulfoxide (SMCSO) is an organosulfur compound with demonstrated hypocholesterolemic, anti-diabetic, and antioxidant benefits in rodents. However, the doses used have limited translatability for humans. We explored…

View details →DOI: 10.1039/d5fo04816h
Negative / Null Result ReportMedicine

Mycorrhizal inoculation and crop rotation as soil sustainable management strategies to reduce fertilizer use and water consumption in horticultural crops

Vargas Ribera PR, Nogales A, Calvet C et al. · 2026 · Applied Soil Ecology.

Crop rotation enhances agroecosystem sustainability by reducing nutrient loss, improving soil fertility, and decreasing crop evapotranspiration. Arbuscular mycorrhizal fungi (AMF) inoculation further supports enhanced nutrient and water…

Negative / Null Result ReportMedicine

A combined Ames and in vivo genotoxicity assessment of dimyricetin-yl-diselenide, a structurally defined organoselenium flavonoid.

Zhang L, Liu X, Zhang C et al. · 2026 · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Dimyricetin-yl-diselenide (DMS; 3,5,7-trihydroxy-8-[[3,5,7-trihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)chromen-8-yl]diselanyl]-2-(3,4,5-trihydroxyphenyl)chromen-4-one) is a structurally defined organoselenium flavonoid dimer in which two…

View details →DOI: 10.1016/j.fct.2026.116172
Negative / Null Result ReportMedicine

Adding Self-directed Psychological Support to Usual Rehabilitation Following Anterior Cruciate Ligament Reconstruction Did Not Increase Return-to-Sport Rates at 12 Months. Results From the BAck iN the Game (BANG) Randomized Controlled Trial.

Fältström A, Hedevik H, Ardern CL et al. · 2026 · The Journal of orthopaedic and sports physical therapy

OBJECTIVE: To evaluate the efficacy of internet-delivered psychological support-the BAck iN the Game (BANG) intervention-after anterior cruciate ligament reconstruction (ACLR) for improving return to sport (RTS). DESIGN: Randomized…

View details →DOI: 10.2519/jospt.2026.13749
Negative / Null Result ReportMedicine

Increasing meniscal repair rates during ACL reconstruction did not increase reoperation risk: An analysis of surgical trends from 2015 to 2023.

Kekki C, Essen CV, Cristiani R et al. · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA

Purpose To evaluate surgical trends over time in meniscal procedures during anterior cruciate ligament reconstruction (ACLR) and compare meniscal reoperation rates and subjective outcomes between 2015-2019 and 2020-2023. Methods This study…

View details →DOI: 10.1002/ksa.70388
Failed Experiment ReportMedicine

Urinary dipstick findings and UTI risk with SGLT2 inhibitors: a post hoc analysis of the CANVAS and CREDENCE trials.

Doi Y, Hamano T, Fukuda-Doi M et al. · 2026 · Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Background and hypothesis Despite established cardiorenal benefits, concerns about urinary tract infection (UTI) risk may limit SGLT2 inhibitor use, especially in high-risk patients. We hypothesized that urine leukocyte esterase (LE) and…

View details →DOI: 10.1093/ndt/gfag062
Negative / Null Result ReportMedicine

Luspatercept and thrombotic events in patients with myelodysplastic syndrome: a target trial emulation framework using TriNetX database.

Vojjala N, Nassar M, Nanjareddy S et al. · 2026 · Leukemia & lymphoma

Myelodysplastic syndrome (MDS) is an identified risk for both venous and arterial thromboembolism (ATE). The thrombotic risk of drugs used in MDS, such as Luspatercept and Erythropoietin-stimulating agents (ESAs), has yielded conflicting…

View details →DOI: 10.1080/10428194.2026.2684311
Negative / Null Result ReportMedicine

A pilot study of a sexual health workshop for oncology staff: feasibility, impact, and gaps in addressing young adult breast cancer survivorship needs.

Rick TJ, Girard A, Topalian A et al. · 2026 · Journal of cancer survivorship : research and practice

Purpose Sexual health concerns are highly prevalent and distressing among adolescent and young adult (AYA) breast cancer survivors, yet are rarely addressed in routine oncology care. Lack of provider training remains a key barrier to…

View details →DOI: 10.1007/s11764-026-01985-8