A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21266 results · page 233 of 709
Ang D, Nathens A, Nayduch D et al. · 2026 · Annals of surgery
Objectives To evaluate whether surgical stabilization of rib fractures (SSRF) improves acute and patient-centered outcomes in adults with clinically significant rib fractures. Summary of background data Rib fractures occur in up to 40% of…
Uehara T, Itoh H, Abe H et al. · 2026 · Psychopharmacology
Rationale Apocynin-tandospirone derivatives (ATDs) have recently been shown to ameliorate methamphetamine (MAP)-induced behavioral abnormalities when administered chronically, presumably through antioxidant and interneuron-related…
Marzo-Escartín B, Villamarín-Melio M, Márquez-Algaba E et al. · 2026 · Surgical infections
Background Peristomal infection (PI) is the most frequent complication following percutaneous gastrostomy, and the increase of multi-drug-resistant (MDR) bacteria poses a therapeutic challenge. We evaluated whether targeted antimicrobial…
Rana CJ, Bakshi SG, Tarhane S et al. · 2026 · Indian journal of surgical oncology
Distract trial In the post-operative period, analgesics are complemented with non-pharmacological methods (NPM). However, the evidence is limited. Objectives Randomised control trial aimed to determine the effectiveness of NPMs of pain…
Porter A, Nguyen J, Peng Y et al. · 2026 · The American journal of sports medicine
Background Intra-articular triamcinolone acetonide (TA) injections are commonly used to manage joint synovitis despite reports that they accelerate cartilage degeneration. Previous studies found that TA minimally affected bovine cartilage,…
Van de Perre E, Tielemans C, De Clerck D et al. · 2026 · Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Background and hypothesis Hyperoxaluria is an important risk factor for kidney stone formation. Currently available treatment options for idiopathic hyperoxaluria have limited efficacy and are difficult to maintain in the long-term.…
Islam IS, McGetrick ME, Leon RL et al. · 2026 · The Annals of thoracic surgery
Background We implemented a preoperative screening brain magnetic resonance imaging (MRI) protocol for neonates undergoing cardiac surgery. The intent was to identify unrecognized central nervous system (CNS) injury that might alter the…
Tian Q, Tian B, Li K et al. · 2026 · Neurosurgical review
The effectiveness of surgical intervention for hydrocephalus in patients with prolonged disorders of consciousness (pDoC) remains controversial. To investigate the impact of ventriculoperitoneal shunt (VPS) on secondary hydrocephalus…
Rasmussen JJ, Bisgaard J, Hønge JL et al. · 2026 · Journal of cardiothoracic and vascular anesthesia
Objectives Managing pain after median sternotomy is a clinical challenge of balancing adequate pain relief with avoidance of excessive opioid consumption. While regional anesthesia techniques are increasingly recommended and applied in…
Tuzlali M, Baki N, Avcu GY et al. · 2026 · Preprint
Background: /Objectives: Full-arch zirconia prostheses for mandibular All-on-4 rehabilitations are provided as screw-retained monolithic zirconia or as a zirconia suprastructure luted to a CAD/CAM titanium bar. Because zirconia is a…
Lenselink E, Ruig M, Grootendorst DC et al. · 2026 · Journal of vascular surgery
Objective Groin wound complications-including surgical site infections, hematomas, seroma leakage, necrosis, and wound dehiscence-are frequently reported after arterial vascular surgery and significantly impact patient morbidity and…
Steelman M, Sutton D, Fox NS · 2026 · American journal of perinatology
This study aimed to evaluate the impact of a modified surgical site infection (SSI) prevention bundle, focused on closing-phase equipment changes, on post-cesarean SSI rates.We conducted a retrospective cohort study of cesarean deliveries…
Neupane D, Richter P, Caffe M et al. · 2026 · Field Crops Research.
Milling markets and farmers demand grain characteristics that are consistent despite weather extremes. These characteristics may also be negatively correlated, such as between yield and nutritional value, thus imposing tradeoffs on…
Jønck S, Adamsen ML, Rasmussen IE et al. · 2026 · Experimental physiology
Excess visceral adipose tissue (VAT) mass increases cardiovascular disease risk. Exercise supports overall health and VAT mass reduction in rheumatoid arthritis (RA). Unlike tumour necrosis factor (TNF), interleukin-6 (IL-6) is upregulated…
Yan Y, Wang X, Fan Z et al. · 2026 · JACC. Asia
Background The RIGHT trial was designed to assess the efficacy and safety of postprocedural anticoagulation (PPA) in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (PCI).…
Irwin M, Leedy N, Nandavaram S et al. · 2026 · Transplant infectious disease : an official journal of the Transplantation Society
Background Clostridioides difficile infection (CDI) is a common complication in patients receiving broad-spectrum antibiotics and causes significant morbidity, especially in solid organ transplant recipients. Oral vancomycin has shown…
Hamdi W, Ben Nessib D, Hashad S et al. · 2025 · European journal of pediatrics
The International League of Associations for Rheumatology (ILAR) classification criteria for juvenile idiopathic arthritis (JIA) are currently widely used in clinical practice. However, new criteria have recently been proposed by the…
Hansen FG, Simonsen M, Wüst M et al. · 2026 · Preprint
This study examined the effects of three couple-focused prevention programs, universally delivered to all couples during the transition to parenthood (TtP), on the rate of family dissolution. Couple-focused prevention programs, such as…
Widiyanti P, Putra AF, Rudyardjo DI · 2026 · The International journal of artificial organs
Perforation on tympanic membrane could decrease the hearing ability. In some cases, myringoplasty should be performed. Myringoplasty requires material as patch to cover tympanic membrane's hole. This study is aimed to create innovation…
Efune PN, Nakonezny PA, Pinales P et al. · 2026 · Journal of clinical anesthesia
Background Protective reflexes like coughing occur frequently during pediatric adenotonsillectomy (AT) and are difficult to blunt with anesthetics, potentially leading to higher than necessary opioid administration. Our objective was to…
Damázio AH, Carlos NR, Basting RT et al. · 2026 · Operative dentistry
Objective Because the application of violet light-emitting diode (LED) light may enhance the release of reactive oxygen species, and its combination with a high-concentration bleaching agents may accelerate collagen degradation, this study…
Ko HR, Cho SY, Kim HS et al. · 2026 · Food science and biotechnology
The East Asian fruit Maesil ( Prunus mume ) is primarily consumed as a sugar extract in South Korea. This stone fruit-derived product contains various forms of potentially toxic cyanide compounds. This study evaluated manufacturing…
Burastero GJ, Wey EQ, Guidetti V et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background Data regarding the effectiveness of vancomycin-resistant Enterococci (VRE)-active prophylaxis for preventing early post-liver transplantation (LT) VRE infections in VRE-colonized patients are scarce. Methods 131 pre-LT…
van Limpt GJC, van Vliet P, Molenaar MA et al. · 2026 · Intensive & critical care nursing
Introduction False or clinically irrelevant alarms are a major driver of ICU alarm fatigue and nursing workload. Ventilator alarms make up a large share, and although automated ventilation modes can reduce manual adjustments, their effect…
Westerhout SF, Remmers S, Bangma CH et al. · 2026 · European journal of cancer (Oxford, England : 1990)
Introduction Prostate-specific antigen (PSA)-based prostate cancer (PCa) screening can be improved by individualised, risk-stratified strategies. Comorbidity influences life expectancy, so may affect benefits of screening. We evaluated…
Ruegg T, Zhao X, Mount MS et al. · 2026 · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Background Telehealth-delivered education offers a practical approach to chemotherapy teaching and symptom self-management support. Advanced practice providers (APPs) play an increasingly vital role in guiding oncology patients through…
Kim J, Park C, Woo KJ et al. · 2026 · Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Concerns regarding donor-site healing persist in abdominal-based free flap breast reconstruction. Although closed-incision negative-pressure therapy (CINPT) has demonstrated wound-related benefits, its efficacy without the use of drains…
Freitas NM, Silva ACA, Tebaldi ND · 2025 · Preprint
Abstract Lettuce bacterial leaf spot, caused by Xanthomonas hortorum pv. vitians is one important pathogen of lettuce. The use of nanoparticles offers a new approach to controlling the disease. The objective of this work was to investigate…
Thorpe A, Lee RA, Szymczak JE et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background Antimicrobial resistance (AMR) is an urgent health threat. Effective communication about AMR and avoiding antibiotics for viral infections is a public health priority. Here, we evaluated whether comparing the AMR crisis to the…
Zelaya IO, Soto ORR, Ventura GPM et al. · 2026 · European journal of midwifery
Introduction Pain and anxiety are common during labor. Evidence on non-pharmacological tools like the peanut ball from public hospital settings in Honduras is limited. This study evaluated its efficacy in reducing pain and anxiety. Methods…