Negative / Null Result Report
Turner TJ, Brun P, Gruber R et al. · 2024 · Preprint
Tolebrutinib is a covalent BTK inhibitor designed and selected for potency and CNS exposure to optimize impact on BTK-dependent signaling in CNS-resident cells. We applied a translational approach to evaluate three BTK inhibitors in Phase…
View details →DOI: 10.1101/2024.03.25.586667 Negative / Null Result ReportOpen accessMedicine
Al-Khalaifah H, Al-Nasser A, Al-Surrayai T · 2025 · Life (Basel, Switzerland)
There is growing interest in adding marine algae to poultry feed rations. The aim of the present study is to examine the effect of various inclusions of Sargassum sp., Gracilaria sp., and Spirulina sp. on productive performance, serum…
View details →DOI: 10.3390/life15040670 Negative / Null Result ReportOpen accessMedicine
Zamora Veliz HY, Paredes Cabanillas RY, Gomez Trejo JE et al. · 2025 · Cureus
Introduction Intestinal anastomotic leakage is a serious postoperative complication associated with high morbidity and mortality. Although acute-phase reactants such as procalcitonin (PCT) and CRP have been proposed as early biomarkers,…
View details →DOI: 10.7759/cureus.88190 Negative / Null Result ReportOpen accessMedicine
Halačová M, Mieresová M, Kubele J et al. · 2026 · Pharmacological reports : PR
BACKGROUND: Beta-lactams are the cornerstone of therapy for the treatment of the most serious infections in the intensive care unit (ICU) setting. However, individualization of dosing remains challenging because pharmacokinetics are highly…
View details →DOI: 10.1007/s43440-026-00836-8 Negative / Null Result ReportOpen accessMedicine
Dumont JR, Sheppard PAS, Fodor C et al. · 2025 · Genes, brain, and behavior
Alzheimer's disease is a debilitating neurodegenerative condition characterized by amyloid beta plaques and tau neurofibrillary tangles, which leads to progressive cognitive decline. Several new mouse models of fast amyloid deposition have…
View details →DOI: 10.1111/gbb.70024 Negative / Null Result ReportMedicine
Langevin P, Frémont P, Fait P et al. · 2024 · Disability and rehabilitation
Purpose The objective of this study was to compare the effects of an in-clinic cervicovestibular rehabilitation program (education, home exercises, manual techniques, sub-symptom threshold aerobic exercise [STAE] program) to a similar…
View details →DOI: 10.1080/09638288.2023.2236016 Negative / Null Result ReportMedicine
Schleifenbaum L, Stern J, Driebe JC et al. · 2024 · Hormones and behavior
Previous research on the endogenous effects of ovarian hormones on motivational states in women has focused on sexual motivation. The Motivational Priority Shifts Hypothesis has a broader scope. It predicts a shift from somatic to…
View details →DOI: 10.1016/j.yhbeh.2024.105542 Negative / Null Result ReportMedicine
Fumagalli D, Sonik R, De Vitis LA et al. · 2024 · Gynecologic oncology
Background Advanced epithelial ovarian cancer (OC) patients often present with malnutrition; however, the ideal nutritional evaluation tool is unclear. We aimed to evaluate the role of preoperative albumin, Prognostic Nutritional Index…
View details →DOI: 10.1016/j.ygyno.2024.06.021 Negative / Null Result ReportOpen accessMedicine
Figueiredo RR, de Azevedo AA, Figueiredo GMR et al. · 2026 · Brazilian journal of otorhinolaryngology
Objectives COVID-19 is a respiratory disease caused by the coronavirus SARS-CoV-2. Previous studies reported cases of tinnitus following COVID infection, most of them mild and with similar characteristics to other forms of tinnitus. Our…
View details →DOI: 10.1016/j.bjorl.2026.101857 Negative / Null Result ReportMedicine
Bello RJ, Palleiko BA, Kennedy K et al. · 2024 · Surgical oncology
Background Pain management following mastectomy is a significant challenge often requiring opioids. Nonopioid pain management utilizing nerve blocks has been shown in other fields to reduce postoperative opioid use and may be effective for…
View details →DOI: 10.1016/j.suronc.2024.102055 Negative / Null Result ReportOpen accessMedicine
Pan L, Kaku Y, Tolentino JE et al. · 2025 · Frontiers in microbiology
In the 21st century, three severe human coronavirus infections have occurred. One of them is the Middle East respiratory syndrome coronavirus (MERS-CoV), a merbecovirus belonging to the family Coronaviridae , is a human pathogenic…
View details →DOI: 10.3389/fmicb.2025.1593095 Negative / Null Result ReportOpen accessMedicine
Khan M, Yousaf H, Naqqash M et al. · 2025 · Cureus
Introduction There is limited local data comparing the outcomes of core decompression and fibular strut grafting in early-stage avascular necrosis (AVN) of the hip. International findings may not be directly applicable due to…
View details →DOI: 10.7759/cureus.92733 Negative / Null Result ReportOpen accessMedicine
Yaşar NF, Badak B, Salış M et al. · 2024 · Revista da Associacao Medica Brasileira (1992)
Objective Endogenous melatonin is produced from tryptophan which is an essential amino acid. Besides its role in the regulation of sleep patterns, melatonin has anti-inflammatory effects. In this case-control study, we aimed to compare…
View details →DOI: 10.1590/1806-9282.20230826 Negative / Null Result ReportOpen accessMedicine
Beaulieu A, Saint-Georges C, Hagbarth I et al. · 2026 · Scientific reports
General movements (GMs) refer to infants’ spontaneous motor activities before the emergence of voluntary motor activity. Abnormal GMs in neonates have been regarded as a marker of poor neurodevelopmental outcomes, with preliminary findings…
View details →DOI: 10.1038/s41598-025-34525-y Negative / Null Result ReportOpen accessMedicine
Iljazi A, Sørensen MS, Winther-Jensen M et al. · 2024 · Acta orthopaedica
Background and purpose Dislocation is a severe complication following total hip arthroplasty (THA). Hip precautions have been recommended in the initial postoperative period but evidence supporting this practice is limited. We therefore…
View details →DOI: 10.2340/17453674.2024.41168 Negative / Null Result ReportMedicine
Klüwer B, Gleditsch R, Rydland KM et al. · 2024 · Vaccine
Aims To explore public confidence in influenza vaccination through the use of attitudinal indicators, and study whether educational attainment is related to attitudes towards influenza vaccination. Methods Confidence in influenza…
View details →DOI: 10.1016/j.vaccine.2024.03.049 Negative / Null Result ReportMedicine
Jang S, Gwak HS, Joo J et al. · 2024 · Acta neurochirurgica
Purpose This study aimed to evaluate the symptomatic response and side effects of ventriculolumbar perfusion (VLP) methotrexate chemotherapy with a low perfusion rate in patients with leptomeningeal metastasis. Methods Patients in a…
View details →DOI: 10.1007/s00701-024-05989-0 Negative / Null Result Report
Chen J, Hou S, Feng R et al. · 2023 · Preprint
CRISPR homing gene drive is a potent technology with considerable potential for managing populations of medically and agriculturally significant insects. It induces a bias in the inheritance of the drive allele in progeny, rapidly…
View details →DOI: 10.1101/2023.11.29.569221 Negative / Null Result Report
nema sk, ramsubramani P, S s · 2023 · Preprint
Abstract Background Transmembrane proteins of the Wnt family and receptor tyrosine kinase (ROR1 and ROR2) suppression or overexpression has been implicated in the causation of cancers. We determined the expression of ROR2 among patients of…
View details →DOI: 10.21203/rs.3.rs-3752427/v1 Negative / Null Result ReportMedicine
Mann S, Juhl CB, Paarup HM et al. · 2024 · Work (Reading, Mass.)
Background Playing the violin often requires a rotated and lateral flexed neck, leading to potential neck and shoulder problems. An ergonomic chinrest (EC) with or without a shoulder rest (SR or WSR) may enhance neutral neck positioning,…
View details →DOI: 10.3233/wor-220518 Negative / Null Result ReportMedicine
Wiener RC, Abuhalimeh B, Cochran J · 2025 · Community dentistry and oral epidemiology
Objective The objective of this research was to determine if the ratio of family income to poverty index is a modifier in the relationship of sugar-sweetened beverages (SSB) and dental caries in U.S. children. Methods A cross-sectional…
View details →DOI: 10.1111/cdoe.70000 Negative / Null Result ReportOpen accessMedicine
Schwarzer NH, Behringer N, Dees P et al. · 2026 · BMC psychology
Background The Epistemic Trust, Mistrust, and Credulity Questionnaire (ETMCQ) assesses individual differences in epistemic stances. Although widely used, its German translation has not yet undergone an independent psychometric evaluation.…
View details →DOI: 10.1186/s40359-026-04810-0 Negative / Null Result ReportOpen accessMedicine
Taniajura N, Rincon C, Kennedy S et al. · 2026 · Addictive behaviors reports
Research has demonstrated that exposure to alcohol-related cues (e.g., sight or smell of a preferred beverage) elicits heightened self-reported craving and psychophysiological responses, including changes in heart rate (HR) and heart rate…
View details →DOI: 10.1016/j.abrep.2026.100687 Negative / Null Result ReportOpen accessMedicine
Barrera G, Albiach-Serrano A, Guillén-Salazar F · 2024 · Animal cognition
Studies have shown that horses are sensitive to human attentional cues. Also, there is some evidence that they might be able to infer the knowledge state of a human and communicate intentionally with us. However, this ability is not fully…
View details →DOI: 10.1007/s10071-024-01909-y Negative / Null Result ReportMedicine
Bansal M, Mehta A, Morris DL et al. · 2025 · Proceedings (Baylor University. Medical Center)
Background This study sought to assess the outcomes of pulmonary embolism (PE) admissions at teaching and nonteaching hospitals in the month of July, when new trainees begin their training in the United States. Methods During 2016-2021,…
View details →DOI: 10.1080/08998280.2025.2520125 Negative / Null Result ReportMedicine
Ruiz VH, Gill CM, Nicolau DP · 2024 · The Journal of antimicrobial chemotherapy
Objectives To evaluate the efficacy of human-simulated regimens (HSRs) of ceftazidime, ceftazidime/avibactam, imipenem, imipenem/relebactam, meropenem and meropenem/vaborbactam in a murine thigh infection model against serine…
View details →DOI: 10.1093/jac/dkad412 Negative / Null Result ReportOpen accessMedicine
Schaefer M, Liedtke C, Enge S · 2025 · Scientific reports
Recent reports challenge the view that placebos need to be given in deception. Numerous studies report remarkable effects when giving placebos honestly in an open way. However, the mechanisms of open-label placebos still remain to be…
View details →DOI: 10.1038/s41598-025-27622-5 Negative / Null Result ReportOpen accessMedicine
Tortolani AF, Kunigk NG, Sobinov AR et al. · 2025 · Journal of neural engineering
Objective . As brain-computer interface (BCI) research advances, many new applications are being developed. Tasks can be performed in different virtual environments, and whether a BCI user can switch environments seamlessly will influence…
View details →DOI: 10.1088/1741-2552/adb078 Negative / Null Result ReportOpen accessMedicine
Rogers ER, Sankarasubramanian V, Kyi WHT et al. · 2025 · Journal of pain research
Purpose The analgesic mechanisms and neurophysiological effects of spinal cord stimulation (SCS) and dorsal root ganglion stimulation (DRGS) are poorly understood. In this pilot repeated-measures study, we used quantitative sensory testing…
View details →DOI: 10.2147/jpr.s519187 Negative / Null Result ReportMedicine
Mauz JB, Rieland H, Berliner D et al. · 2024 · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Background & aims Considerate patient selection is vital to ensure the best possible outcomes after transjugular intrahepatic portosystemic shunt (TIPS) insertion. However, data regarding the impact of intrapulmonary vascular dilatations…
View details →DOI: 10.1016/j.cgh.2024.04.027 