Negative / Null Result ReportOpen accessMedicine
Pimentel V, Becker J · 2025 · Arquivos de neuro-psiquiatria
Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune demyelinating disease characterized by a high risk of relapse and disability. In cases positive for aquaporin 4-immunoglobulin G (AQP4-IgG), long-term immunosuppression…
View details →DOI: 10.1055/s-0045-1814370 Negative / Null Result ReportOpen accessMedicine
Mazzotta E, Natale A, Bellinati L et al. · 2025 · Animals : an open access journal from MDPI
Equid milk (donkey or mare) has traditionally been consumed raw or fermented due to its distinctive chemical composition, which closely resembles human milk, and its nutritional benefits. Nowadays, interest in it is increasing, despite…
View details →DOI: 10.3390/ani15101460 Negative / Null Result ReportOpen accessMedicine
Bai M, Li Y, Gao Q et al. · 2025 · Virology journal
Purpose Present study aimed to compare the boiling and magnetic bead nucleic acid extraction method for HPV genotypes detection. Methods By mixing hemoglobin with HPV positive quality control products, the anti-interference ability of two…
View details →DOI: 10.1186/s12985-025-02999-x Negative / Null Result ReportOpen accessMedicine
Limaye AP, Crespo M, Kamar N et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background QuantiFERON-cytomegalovirus (QFT-CMV) is a standardized assay for the evaluation of cytomegalovirus-specific cell-mediated immunity (CMV-CMI). Objectives The purpose of this study was to assess the evolution of CMV-CMI…
View details →DOI: 10.1093/cid/ciaf632 Negative / Null Result ReportMedicine
Wang X, Fan Z, Huo L et al. · 2025 · Breast care (Basel, Switzerland)
Background In sentinel node biopsy (SNB) procedure for breast cancer patient, whether the abnormal node was excised is uncertain. The impact of abnormal node on the accuracy of SNB results is unknown. Methods In this prospective study,…
View details →DOI: 10.1159/000548074 Negative / Null Result ReportMedicine
Russo F, Chatterjee D, DeMaria N et al. · 2024 · Journal of community genetics
DNA-based population screening for adult-onset diseases holds promise for advancing personalized medicine and improving public health. Yet as most individuals pursuing such screening receive negative results, the return of results process…
View details →DOI: 10.1007/s12687-024-00736-5 Negative / Null Result ReportOpen accessMedicine
Roman TS, Gray SM, Sneddon TP et al. · 2026 · HGG advances
The impact of clinical exome and genome sequencing (ES/GS) depends on the clinical setting. In the sequencing arm of a multifactor randomized clinical trial to evaluate broadening access, we assessed the diagnostic and inconclusive…
View details →DOI: 10.1016/j.xhgg.2026.100605 Negative / Null Result ReportOpen accessMedicine
Bölük S, Bölük S · 2025 · Cureus
Background In breast cancer surgery, sentinel lymph node biopsy (SLNB) is routinely utilized for axillary assessment. Frozen section examination of the sentinel lymph node (SLN) is used to guide the decision for axillary dissection.…
View details →DOI: 10.7759/cureus.85891 Negative / Null Result ReportOpen accessMedicine
Triantafyllidou O, Panagodimou E, Chasiakou S et al. · 2026 · Cureus
Objective To evaluate whether the addition of clomiphene citrate (CC) to a low-dose recombinant follicle-stimulating hormone (FSH) (r-FSH) gonadotropin-releasing hormone (GnRH)-antagonist protocol improves clinical outcomes in women with…
View details →DOI: 10.7759/cureus.108079 Negative / Null Result ReportMedicine
Buteau JP, Moon D, Fahey MT et al. · 2026 · The Lancet. Oncology
Background MRI is recommended for men with clinical suspicion of significant prostate cancer. Those with high clinical risk but non-suspicious or equivocal MRI often undergo prostate biopsy, but have a low likelihood of clinically…
View details →DOI: 10.1016/s1470-2045(26)00120-8 Negative / Null Result ReportMedicine
Paturu T, Shukla A, Shivan SG et al. · 2024 · Journal of cataract and refractive surgery
Evidence-based decision-making is generally based on published evidence. Therefore, if the published evidence is biased, so will the decision-making. One possible bias is the "positive-results" publication bias. This study attempts to…
View details →DOI: 10.1097/j.jcrs.0000000000001516 Negative / Null Result ReportMedicine
Lydia S, Blaise G · 2024 · Journal of travel medicine
Background When malaria is suspected in case of fever after travel in endemic areas, the current recommendation is to repeat the malaria test at 24-hour intervals, with up to two additional tests, as long as the test result is negative. A…
View details →DOI: 10.1093/jtm/taae030 Negative / Null Result ReportOpen accessMedicine
Teixeira J, Teixeira D, Coelho A et al. · 2026 · Dermatology practical & conceptual
Introduction Systemic amyloidosis is a rare disorder characterized by extracellular amyloid deposition in tissues, leading to variable organ dysfunction. Abdominal wall fat pad biopsy is widely used as a minimally invasive diagnostic…
View details →DOI: 10.5826/dpc.1602a6917 Failed Experiment ReportOpen accessMedicine
Montaño AM, Robledo C, Galvis-Ayala JC et al. · 2025 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Purpose To determine diagnostic validity of MALDI-TOF MS (VITEK MS) system for detecting Klebsiella pneumoniae carbapenemases (KPC)-type carbapenemases by identifying the 11,109 Da peak in the mass spectrum generated for species…
View details →DOI: 10.1007/s10096-025-05097-6 Replication FailureMedicine
Kumar S, Sahu S, Sharma S · 2025 · Phlebology
ObjectivesAn open label, single-centric, post market clinical study was undertaken to evaluate the safety and efficacy of a new antimicrobial wound dressing (VELVERT) as an adjuvant therapy in the treatment of venous leg ulcer…
View details →DOI: 10.1177/02683555241288729 Negative / Null Result ReportOpen accessMedicine
Jean J, Sukhanova M, Dittmann D et al. · 2024 · Case reports in hematology
Chronic myeloid leukemia (CML) is associated with several breakpoint regions that result in different BCR::ABL1 fusion transcripts. These include the major breakpoint region (M-BCR), minor breakpoint region (m-BCR), and mu breakpoint…
View details →DOI: 10.1155/2024/8486267 Negative / Null Result ReportOpen accessMedicine
Mateuszczyk MK, Łyko M, Bieniek A et al. · 2025 · Clinics and practice
Background: Adverse reactions to tattoo pigments are increasingly recognized, yet severe systemic complications remain rare and poorly characterized. Red tattoo ink, in particular, is associated with delayed hypersensitivity reactions, but…
View details →DOI: 10.3390/clinpract15120224 Failed Experiment ReportOpen accessMedicine
Olbrich A, Motekallemi A, Deschka H et al. · 2025 · Interdisciplinary cardiovascular and thoracic surgery
Objectives Driveline infection (DLI) is a common complication in patients with left ventricular assist devices. This complication can seriously undermine quality of life while on left ventricular assist devices. Current diagnosis of a DLI…
View details →DOI: 10.1093/icvts/ivae215 Negative / Null Result ReportOpen accessMedicine
Chunkul S, Sathirapatya T, Dangklao P et al. · 2025 · Forensic science international. Synergy
Sexual assault is a terrible crime that demands a comprehensive and skilled investigation to gather the perpetrator's biological material. To collect all possible physical and biological evidence, forensic investigation is crucial and…
View details →DOI: 10.1016/j.fsisyn.2024.100567 Negative / Null Result ReportMedicine
Liu Q, Liu X, Chang L et al. · 2025 · Clinica chimica acta; international journal of clinical chemistry
Introduction Accurate and early HIV detection is crucial for improving outcomes and controlling transmission. This study compares HIV marker patterns and evaluates detection assay performance in general screening and ART-treated…
View details →DOI: 10.1016/j.cca.2025.120207 Negative / Null Result ReportMedicine
Ma F, Hu J, Bai M et al. · 2024 · Clinical laboratory
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection typically relies on reverse transcription-polymerase chain reaction (RT-PCR) technology. However, there is a certain rate of missed detection of SARS-CoV-2…
View details →DOI: 10.7754/clin.lab.2024.240404 Negative / Null Result ReportOpen accessMedicine
Lauffer P, van Weelden W, van Haelst MM et al. · 2025 · Journal of community genetics
Polygenic risk scores (PRS) have emerged as a potential tool for predicting complex genetic traits and disorders, which may complement traditional rare variant testing. As genome-wide association studies (GWAS) expand, PRS predictive…
View details →DOI: 10.1007/s12687-025-00835-x Negative / Null Result ReportOpen accessMedicine
Cassileth LB, Killeen K, York A et al. · 2026 · Aesthetic surgery journal. Open forum
Background Mastectomy skin flap necrosis (MSFN) is a critical postoperation complication in postmastectomy breast reconstruction. High replacement tissue expander fill volume and large mastectomy specimen size are commonly assumed to…
View details →DOI: 10.1093/asjof/ojag063 Negative / Null Result ReportOpen accessMedicine
Akella JS, Onken BD, Sedore CA et al. · 2026 · microPublication biology
The Caenorhabditis Intervention Testing Program aims to identify lifespan-extending interventions that are effective across diverse genetic backgrounds. Previous studies identified a role for anticonvulsants in lifespan extension in the…
View details →DOI: 10.17912/micropub.biology.001987 Negative / Null Result ReportOpen accessMedicine
Jones GT, Bennett AN, Sengupta R et al. · 2025 · Arthritis care & research
Objective Imaging evidence of active sacroiliitis is important for diagnosis, classification, and monitoring of axial spondyloarthritis (axSpA). However, there is no consistent guidance on whether patients should temporarily stop…
View details →DOI: 10.1002/acr.25581 Negative / Null Result ReportOpen accessMedicine
Karlsen KL, Clausen CL, Kahiyah RAS et al. · 2026 · Open forum infectious diseases
Background Adults hospitalized with respiratory syncytial virus (RSV) face mortality risks comparable to or higher than those with influenza A or B. However, studies on the impact of bacterial co-infections on mortality are inconsistent.…
View details →DOI: 10.1093/ofid/ofaf778 Methods Dead-EndOpen accessMedicine
van Orten-Luiten ACB, Brouwer-Brolsma EM, Janse A et al. · 2025 · European journal of clinical pharmacology
Purpose Chronic hyponatremia in older people is associated with adverse outcomes including gait disturbances, falls, osteoporosis, fractures, cognitive impairment, and cardiovascular disease. Diagnosis in outpatient settings is challenging…
View details →DOI: 10.1007/s00228-025-03890-y Negative / Null Result ReportOpen accessMedicine
Kocaaslan H, Ceylan C, Sümer F et al. · 2026 · BMC surgery
PURPOSE: In non-metastatic advanced gastric cancer, gastrectomy with D2 lymph node dissection is the main curative treatment. The clinical benefit of omentectomy in gastric cancer surgery is still controversial. We planned to investigate…
View details →DOI: 10.1186/s12893-026-03533-8 Negative / Null Result ReportOpen accessMedicine
Domche A, Nomo A, Yemele RD et al. · 2026 · BMC ophthalmology
BACKGROUND: Loiasis is a parasitic disease caused by the filarial nematode Loa loa. CASE PRESENTATION: This report describes loiasis in a 6-year-old child presented to a public hospital in Yaoundé, Cameroon, with an immobile worm located…
View details →DOI: 10.1186/s12886-025-04547-1 Negative / Null Result ReportOpen accessMedicine
Trka J, Fronkova E · 2025 · British journal of haematology
Can peripheral blood be used to detect residual disease in acute lymphoblastic leukaemia (ALL) when we increase the sensitivity of the method used? Bendig et al. found that a larger amount of material and the use of next-generation…
View details →DOI: 10.1111/bjh.19888 