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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21707 results · page 226 of 724

Negative / Null Result ReportMedicine

Interplay Among Reward Processing, Schizotypal Traits, and Psychosocial Stress in a Large Chinese Young Adult Sample: A Cross‐Sectional Network Analysis

Donghao Tuo, Yi-hang Huang, Simon S. Y. Liu et al. · 2026 · PsyCh Journal

ABSTRACT Reward processing comprises reward sensitivity, motivation, and pleasure experience, but how these components jointly relate to schizotypal traits and psychosocial stress in young adult samples remains unclear. Using network…

View details →DOI: 10.1002/pchj.70102
Negative / Null Result ReportMedicine

Glutathione S-transferase expression in benign and malignant eyelid tumors

Efe Saygın, R. Karadag, S. Ozkanlı et al. · 2021 · Biotechnic & Histochemistry

ABSTRACT Eyelid tumors commonly originate from the skin and its appendages. Environmental toxins and oxidants affect eyelid carcinogenesis. Glutathione S-transferases (GST) are antioxidants that participate in pathogenesis. We investigated…

View details →DOI: 10.1080/10520295.2021.1986133
Negative / Null Result ReportMedicine

Magnetic resonance imaging-based detection of retinal hemorrhages in a multicenter cohort of abusive head trauma

M. Hahnemann, B. Karger, S. Banaschak et al. · 2026 · Pediatric Radiology

Background In pediatric abusive head trauma (AHT), retinal hemorrhages are a key diagnostic feature. Detection by fundoscopy may be delayed or limited, whereas magnetic resonance imaging (MRI) enables non-invasive, objective assessment on…

View details →DOI: 10.1007/s00247-026-06558-6
Negative / Null Result ReportOpen accessGeography

An Empirical Study on Different Tendencies toward Indulgence-Restraint Dimension from the Intercultural Perspective —In the Case of Guangdong Province

Cai Jie, L. Jing · 2015

With the booming development of economic globalization nowadays, intercultural communication becomes more and more important. Based on Hofstede’s indulgence-restraint dimension, this thesis aims to testify whether Hofstede’s opinion that…

View details →DOI: 10.4236/chnstd.2015.44017
Negative / Null Result ReportOpen accessMedicine

Differences in social perception in people with schizophrenia and bipolar disorder

Álvaro Cavieres, Vanessa Acuña, M. Arancibia et al. · 2023 · Schizophrenia Research: Cognition

People with schizophrenia have difficulties recognizing other people's expressions, emotional states, and intentions; however, much less is known about their ability to perceive and understand social interactions. We used scenes depicting…

View details →DOI: 10.1016/j.scog.2023.100286
Negative / Null Result ReportOpen accessMedicine

Effect of daily versus intermittent iron therapy in pregnant women: hematological and pregnancy outcome

S. K. Agrawal, M. Jindal · 2020 · Obsgyne Review: Journal of Obstetric and Gynecology

Background: The purpose of this study was to compare daily iron supplementation and intermittent iron supplementation in preventing anemia in healthy pregnant women. Material and Method: Prospective Randomized Clinical Trial. From May 2004…

View details →DOI: 10.17511/joog.2020.i03.01
Negative / Null Result ReportOpen access

Use of boron sources and doses in the industrial tomato under irrigation

R. D. da Silva · 2023 · Pakistan Journal of Agricultural Sciences

Boron sources and doses can positively increase fruit quality and tomato yield. This study aimed to evaluate the influence of boron doses and sources on the development and yield of industrial tomatoes under irrigation. A randomized block…

View details →DOI: 10.21162/pakjas/23.1002
Negative / Null Result ReportOpen accessMedicine

Gender does not appear to play a role in biometry prediction error and intra‐ocular lens power calculation

Vinay Kansal, M. Schlenker, I. Ahmed · 2019 · Acta ophthalmologica

revealed that plasma cortisol in diabetic patients had a 18% and 21% drop from the baseline at day 7 (from 110 to 90 ng/ ml, p = 0.032) and day 21 (from 110 to 86 ng/ml, p = 0.027) as seen in Fig. 1. For RVO patients, the drops were not…

View details →DOI: 10.1111/aos.14101
Negative / Null Result ReportOpen accessPsychology

Satisfação profissional de enfermeiros que atuam no bloco cirúrgico de um hospital de excelência

Lúcia Helena de Almeida Gouveia, V. Ribeiro, R. Carvalho · 2020

Objectives: To analyze and compare the professional satisfaction index (PSI) of surgical block (SB) nurses. Method: Comparative and quantitative field study that used the PSI in the evaluation of autonomy, interaction, compensation,…

View details →DOI: 10.5327/z1414-4425202000010006
Negative / Null Result ReportOpen access

Comparison of the Effect of Eight Week Training Program Schedule With Two Different Stretching Patterns Strengthening on Changes in the Status of Lower Cross Syndrome

Chiman َ Alyarnezhad, Ali Shams Majalan · 2021 · Journal of Sport Biomechanics

Objective: Different timing of performing stretching and strengthening exercises can have different effects on the condition of Lower Crossed Syndrome (LCS). This study aims to compare the effects of eight-week training using stretching…

View details →DOI: 10.32598/biomechanics.7.2.3
Negative / Null Result ReportMedicine

Is There Postoperative Fluid Accumulation After the Unilateral Biportal Endoscopic Technique as Minimally Invasive Spine Surgery: In Vivo Study.

Omer Bozduman, Kadri Yıldız, Bilal Aykaç et al. · 2025 · Turkish Neurosurgery

AIM To establish the presence and amount of fluid accumulation in UBE procedure, and the relationship of fluid management with other variables. MATERIAL AND METHODS All patients underwent UBE spinal surgery with one level between September…

View details →DOI: 10.5137/1019-5149.jtn.47037-24.1
Negative / Null Result ReportOpen accessMedicine

The effectiveness of generic emails versus a remote knowledge broker to integrate mood management into a smoking cessation programme in team-based primary care: a cluster randomised trial

N. Minian, Sheleza Ahad, Anna Ivanova et al. · 2021 · Implementation Science

Background Knowledge brokering is a knowledge translation approach that has been gaining popularity in Canada although the effectiveness is unknown. This study evaluated the effectiveness of generalised, exclusively email-based prompts…

View details →DOI: 10.1186/s13012-021-01091-6
Failed Experiment ReportOpen access

Growth Performance of Crossbred Goat (Beetal ×Assam Local) by Feeding Cultivated Fodder under Intensive Farming

L. D. Singha, G. Saikia, B. Saikia et al. · 2022 · International Journal of Current Microbiology and Applied Sciences

The small ruminant husbandry sector in India is not an organized sector like poultry, however, now-a- days many young entrepreneurs are setting up goat units using scientific rearing practices, because small ruminants play an important…

View details →DOI: 10.20546/ijcmas.2022.1109.006
Negative / Null Result ReportOpen accessMedicine

Effect of isolated and combined ingestion of caffeine and citrulline malate on resistance exercise and jumping performance: a randomized double-blind placebo-controlled crossover study

M. Haugen, F. T. Vårvik, J. Grgic et al. · 2023 · European Journal of Nutrition

The aim of this study was to explore the isolated and combined effects of caffeine and citrulline malate (CitMal) on jumping performance, muscular strength, muscular endurance, and pain perception in resistance-trained participants. Using…

View details →DOI: 10.1007/s00394-023-03212-x
Failed Experiment ReportOpen accessMedicine

Effects of Clobetasol in an Aging Mouse Model of Spinal Cord Hemisection.

Ciuro M, Sangiorgio M, Cantone G et al. · 2025 · Biology

Spinal cord injury leads to permanent neurological deficits, and aging further diminishes the plasticity and regenerative responses required for recovery. Activation of the Sonic hedgehog (Shh) pathway through the receptor Smoothened (Smo)…

View details →DOI: 10.3390/biology14111595
Negative / Null Result ReportMedicine

Prognosis and Therapy of Ovarian Cancer, Part 3: Follow-Up Care, Recurrence, and Screening, the Full Round Circle.

El Housheimi A, Tato Varela S, Kuhn WC · 2026 · Oncology research and treatment

Background Ovarian cancer (OC) accounts for the most cancer deaths in women worldwide, despite it being the 8th most common one. Almost two-thirds or OC cases present in advanced stages (III/IV) and will require maintenance therapy lasting…

View details →DOI: 10.1159/000547282
Negative / Null Result ReportOpen accessMedicine

Bilateral Subdural Hematoma Caused by Cervical Traction.

Mano T · 2025 · Clinical medicine insights. Case reports

Cervical traction therapy is commonly used for cervical spondylosis; however, complications, such as subdural hematomas can occur. Possible mechanisms include cerebrospinal fluid (CSF) leakage and bridging vein damage. A 51-year-old…

View details →DOI: 10.1177/11795476251376464
Negative / Null Result ReportOpen accessMedicine

Breaking the stalemate: a case of a laser-accelerated healing of a chronic tendon-exposed diabetic foot ulcer.

Serour MH, Mohammad H, Aziza O et al. · 2026 · Journal of surgical case reports

Chronic diabetic foot ulcers remain a major clinical challenge, particularly when complicated by tendon exposure and failure to respond to standard care. We report a 47-year-old male with Type II diabetes mellitus with a history of smoking…

View details →DOI: 10.1093/jscr/rjag109
Replication FailureOpen accessMedicine

Paraneoplastic Anti-N-methyl-D-aspartate Receptor Encephalitis Associated with Small Cell Lung Cancer: A Dramatic Recovery after Chemotherapy.

Yano K, Ishida T, Yokosuka K et al. · 2026 · Internal medicine (Tokyo, Japan)

Tumor management is the cornerstone of treatment for anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis that is refractory to immunosuppressive therapy. However, little is known about the effectiveness of chemotherapy for…

View details →DOI: 10.2169/internalmedicine.5586-25
Negative / Null Result ReportMedicine

Novel immunotherapy combinations in head and neck squamous cell carcinoma.

Kankotia S, Park S, Thomas J · 2025 · Current opinion in oncology

Purpose of review Relapsed or metastatic head and neck squamous cell carcinoma (R/M HNSCC) is a deadly disease that historically was treated with palliative chemotherapy-based regimens. Since 2019, immunotherapy-based regimens have become…

View details →DOI: 10.1097/cco.0000000000001127
Negative / Null Result ReportOpen accessMedicine

The Intertransverse Approach for far Lateral Lumbar Disk Herniation: Case Series of 60 Patients and Review of the Literature.

Glauser G, Kvint S, Ramayya AG et al. · 2025 · Neurosurgery practice

Background and objectives The purpose of the present work was to review our series of patients with far lateral disk herniations treated by the intertransverse approach. Methods Patients undergoing intertransverse approach to treat…

View details →DOI: 10.1227/neuprac.0000000000000165