Modeling IK1 current modulation by melatonin and luzindole: a benchmark for patch clamp studies
Gonotkov MA; Safiulina VF · 2026 · Preprint
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Whole-cell patch-clamp studies often fail to observe the expected effect of melatonin on the IK1 current in cardiomyocytes, which may be due to cytoplasmic dialysis and the loss of key components of the intracellular signaling system. The…
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Metadata source: Europe PMC · DOI 10.64898/2026.02.04.703771