Negative / Null Result ReportMedicine
Ramsburg H, Hinkle JL, MacKenzie Greenle M · 2026 · The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses
Background Each year in the United States, 795,000 people are diagnosed with a new or recurrent stroke, resulting in 165,393 deaths. However, little is known about the quality of end-of-life (EOL) care in this population, including the…
View details →DOI: 10.1097/jnn.0000000000000883 Negative / Null Result ReportMedicine
Bitar G, Fishel Bartal M · 2025 · Diabetes spectrum : a publication of the American Diabetes Association
Current recommendations encourage strict intrapartum glycemic control for individuals with diabetes in pregnancy to optimize maternal and neonatal outcomes. However, established evidence is limited in providing a strong association between…
View details →DOI: 10.2337/dsi25-0010 Negative / Null Result ReportOpen accessMedicine
Hulsmann SC, Zaal DC, van Gestel JPJ et al. · 2026 · Pituitary
PURPOSE: Children undergoing neurosurgery for (supra)sellar tumors are at risk of developing arginine vasopressin-deficiency (AVP-D), which can cause severe sodium fluctuations and associated neurological complications, prolonged…
View details →DOI: 10.1007/s11102-026-01666-w Negative / Null Result ReportMedicine
Siokas V, Liampas I, Aloizou AM et al. · 2023 · Journal of integrative neuroscience
Background Microglial activation is considered to assume a role in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). To date, the relationship between ALS and the rs3865444 polymorphism of the cluster of differentiation 33 (CD33)…
View details →DOI: 10.31083/j.jin2204106 Negative / Null Result Report
Wattacheril J, Kleinstein SE, Shea PR et al. · 2024 · Preprint
Background and Aims Nonalcoholic Fatty Liver Disease (NAFLD) is a complex human disease. Common genetic variation in the patatin-like phospholipase domain containing 3 ( PNPLA3 ) and transmembrane 6 superfamily member 2 ( TM6SF2 ) genes…
View details →DOI: 10.1101/2024.03.02.24303632 Negative / Null Result ReportOpen accessMedicine
Curtis A, Skvarc D, Brittain N et al. · 2025 · Drug and alcohol review
Introduction Substance use has been associated with child-to-parent violence (CPV), yet little is known about the contributing factors. This study investigated the association between parental substance use and substance involved child to…
View details →DOI: 10.1111/dar.14031 Negative / Null Result ReportOpen accessMedicine
D'Marco L, Checa-Ros A, Locascio A et al. · 2025 · Frontiers in medicine
Background Several studies suggest that C-peptide (CP) is involved in regulating lipolysis, adipokine release, and other functions in the adipose tissue. On the other hand, organ-specific adipose tissues, such as the epicardial adipose…
View details →DOI: 10.3389/fmed.2025.1650859 Negative / Null Result ReportOpen accessMedicine
Nguyen TT, Pineda R, Reynolds S et al. · 2026 · Physical & occupational therapy in pediatrics
Aim To examine the relationship between feeding therapy and the timing of independent oral feeding (IOF) in preterm infants in the neonatal intensive care unit (NICU). Study design A retrospective analysis of 536 preterm infants ( Results…
View details →DOI: 10.1080/01942638.2025.2552136 Negative / Null Result ReportOpen accessMedicine
Stankovic M, Weber C, Koser M et al. · 2025 · Journal of frailty, sarcopenia and falls
Objectives While chronological aging does not necessarily impair oncological outcomes after radical prostatectomy, the role of frailty remains less clear. This study aimed to evaluate whether frailty significantly affects early continence…
View details →DOI: 10.22540/jfsf-10-028 Negative / Null Result ReportOpen accessMedicine
Keser CS, Erdemir M, Yilmaz M et al. · 2025 · BMC nephrology
Background Hemodynamic instability related to renal replacement therapy (HIRRT) is a serious complication of continuous renal replacement therapy (CRRT) in critically ill patients with acute kidney injury (AKI), significantly increasing…
View details →DOI: 10.1186/s12882-025-04712-0 Negative / Null Result ReportOpen accessMedicine
Smith CM, Spalt EW, Gallo LC et al. · 2026 · Journal of urban health : bulletin of the New York Academy of Medicine
Neighborhood-scale environmental factors, including disinvestment in infrastructure, may impact cardiometabolic disease risk. To our knowledge, no prior studies have investigated the association between neighborhood disinvestment and…
View details →DOI: 10.1007/s11524-026-01061-7 Negative / Null Result ReportOpen accessMedicine
Ihle-Hansen H, Walle-Hansen MM, Berge T et al. · 2026 · BMJ open
Background Current expert consensus statements generally suggest cardiovascular risk assessment, including atrial fibrillation (AF) screening, on detection of covert brain infarctions (CBIs). However, evidence to guide management of CBI…
View details →DOI: 10.1136/bmjopen-2025-114232 Negative / Null Result ReportOpen accessMedicine
Abdalla M · 2026 · Frontiers in medicine
Background Hormone replacement therapy (HRT) is widely prescribed for managing menopausal symptoms, yet its effects on the endometrium remain clinically important. While large-scale studies have established that estrogen-only HRT increases…
View details →DOI: 10.3389/fmed.2026.1718508 Negative / Null Result ReportMedicine
O'Brien EA, Wypij D, Rofeberg V et al. · 2026 · Journal of perinatology : official journal of the California Perinatal Association
Objective Investigate the association between placental vascular abnormalities and regional brain volumes in congenital heart disease (CHD) fetuses with and without genetic abnormalities. Study design Secondary analysis of brain magnetic…
View details →DOI: 10.1038/s41372-026-02601-4 Negative / Null Result ReportOpen accessMedicine
Errigo A, Dore MP, Mocci G et al. · 2024 · Scientific reports
More than two decades ago, in the central-eastern region of the Mediterranean island of Sardinia, a mountain area was identified where the population displays exceptional longevity, especially among men (the Longevity Blue Zone, LBZ). This…
View details →DOI: 10.1038/s41598-024-80497-w Negative / Null Result ReportOpen accessMedicine
Feld RS, Ianiero MA, Goncharow MK et al. · 2026 · Current developments in nutrition
Background Menopause is associated with increases in visceral adipose tissue, reductions in lean mass, and a reduced energy expenditure. The ovariectomized (OVX) rat model can be used to model these changes and to test potential…
View details →DOI: 10.1016/j.cdnut.2026.107656 Negative / Null Result ReportOpen accessMedicine
van der Stouwe AMM · 2024 · Brain communications
This scientific commentary refers to 'Deep brain stimulation does not modulate resting-state functional connectivity in essential tremor', by Awad et al. (https://doi.org/10.1093/braincomms/fcae012).
View details →DOI: 10.1093/braincomms/fcae060 Negative / Null Result ReportOpen accessMedicine
Fukuda R, Hashimoto R, Pak K et al. · 2026 · Health science reports
Background and aims Atopic dermatitis (AD) is characterized by impaired skin barrier function and reduced moisturizing factors. Moisturizers and emollients restore the barrier through distinct mechanisms, but their longitudinal molecular…
View details →DOI: 10.1002/hsr2.72671 Negative / Null Result ReportMedicine
Pimenta GF, Dourado TMH, de Souza KDB et al. · 2025 · Cell biochemistry and function
Increased oxidative stress and apoptosis are key mechanisms of thymic atrophy induced by cyclophosphamide (CYP). Atrophy leads to changes in the thymic microenvironment and disrupts T cell maturation. The hormone melatonin displays…
View details →DOI: 10.1002/cbf.70052 Negative / Null Result Report
Cauich-Suárez LY, Sánchez-Sánchez VE, Moreno-Ortiz GE et al. · 2024 · Preprint
This study employed the Allium cepa bioassay to evaluate the toxic effects of contaminants in the Yucatan aquifer. Seven monitoring wells were studied during September and October 2021. Nutrient concentrations showed significant variation…
View details →DOI: 10.20944/preprints202409.0818.v1 Negative / Null Result ReportOpen accessMedicine
Vasilev V, Georgieva K, Arabadzhiyska D et al. · 2025 · Naunyn-Schmiedeberg's archives of pharmacology
Selective androgen receptor modulators are currently not approved but are widely used in gyms. In the present study, the effects of ligandrol and its combination with endurance training on functional and clinically important parameters…
View details →DOI: 10.1007/s00210-025-04028-8 Negative / Null Result ReportMedicine
Makhlin I, Demissei BG, D'Agostino R et al. · 2024 · Clinical cancer research : an official journal of the American Association for Cancer Research
Purpose Preventing Anthracycline Cardiovascular Toxicity with Statins (PREVENT; NCT01988571) randomized patients with breast cancer or lymphoma receiving anthracyclines to atorvastatin 40 mg daily or placebo. We evaluated the effects of…
View details →DOI: 10.1158/1078-0432.ccr-23-3952 Negative / Null Result ReportOpen accessMedicine
Teipel S, Tang Y, Khachaturian A · 2025 · Alzheimer's & dementia (New York, N. Y.)
Introduction We aimed to determine the clinical efficacy of treating apolipoprotein E (ApoE) ε4 homozygotes with recently approved anti-amyloid antibodies. Methods Data were derived from supplementary analyses in the regulatory studies…
View details →DOI: 10.1002/trc2.70083 Negative / Null Result ReportMedicine
Haggarty CJ, Glazer JE, Nusslock R et al. · 2024 · Psychopharmacology
Introduction Stimulant drugs are thought to alter processing of rewarding stimuli. However, the mechanisms by which they do this are not fully understood. Method In this study we used EEG to assess effects of single doses of…
View details →DOI: 10.1007/s00213-023-06475-8 Negative / Null Result ReportOpen accessMedicine
Aquino-Canchari CR, Parraga Camayo EF, Ambrosio Huaman EN et al. · 2025 · Revista cientifica odontologica (Universidad Cientifica del Sur)
Introduction Dental caries and nutritional alterations are common in childhood, particularly in rural communities with limited access to health services. Objective To determine the association between anthropometric indicators and the…
View details →DOI: 10.21142/2523-2754-1304-2025-264 Negative / Null Result ReportOpen accessMedicine
Maleki M, Modarresi S · 2025 · BMC research notes
Background Orthopedic injuries can negatively impact both the physical and mental health of patients. Ensuring patient satisfaction with their recovery is crucial for meeting patient-centered goals and enhancing overall health outcomes.…
View details →DOI: 10.1186/s13104-025-07210-6 Negative / Null Result ReportMedicine
Bogari NM, Naffadi HM, Babalghith AO et al. · 2024 · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Background Ischemic injury is a common mechanism in both ischemic stroke (IS) and acute coronary syndrome (ACS). Matrix metalloproteinase 9 (MMP-9), an endopeptidase that degrades extracellular matrix, is important in the pathogenesis of…
View details →DOI: 10.1016/j.jstrokecerebrovasdis.2024.107824 Negative / Null Result ReportOpen accessMedicine
Aydın MZ, Arin CB, Teber MK et al. · 2026 · Journal of inflammation research
Background Systemic inflammatory and nutritional indices have been associated with coronary artery disease burden and prognosis; however, their ability to predict lesion-level functional ischemia remains uncertain. This study evaluated…
View details →DOI: 10.2147/jir.s585010 Negative / Null Result ReportOpen accessMedicine
Tungjitviboonkun S, Schulte B, Shi K et al. · 2026 · Cancer medicine
Background Chronic kidney disease (CKD) is a common comorbidity among cancer patients and may influence treatment options and outcomes. However, the independent effect of CKD in patients with hematologic malignancies remains unclear.…
View details →DOI: 10.1002/cam4.72055 Negative / Null Result ReportOpen accessMedicine
George MD, Gavigan K, Venkatachalam S et al. · 2026 · ACR open rheumatology
Objective People with rheumatoid arthritis (RA) are at increased risk of serious infection, but less is known about nonserious infections. Our prospective cohort study evaluated associations between medications for RA and the risk of…
View details →DOI: 10.1002/acr2.90050 