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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21257 results · page 211 of 709

Negative / Null Result ReportOpen accessComputer Science

Search for anisotropic effects of hcp solid helium on optical lines of cesium impurities

Mathieu Melich, Jacques Dupont-Roc, Philippe Jacquier · 2007 · arXiv

The anisotropic effect of a hcp 4He solid matrix on cesium atoms has been proposed as a tool to reveal the parity violating anapole moment of its nucleus. It should also result in splitting the D2 optical excitation line in a way depending on the light polarization. An experimental investigation has been set up using oriented hcp helium crystals in which cesium metal grains are embedded. Atoms are created by laser sputtering from this grains. Optical absorption spectra of the D2 line have been recorded in the temperature range of 1.0 to 1.4 K at liquid/solid coexistence pressure by monitoring

Negative / Null Result ReportOpen accessComputer Science

Understanding the Effects of the Baidu-ULTR Logging Policy on Two-Tower Models

Morris de Haan, Philipp Hager · 2024 · arXiv

Despite the popularity of the two-tower model for unbiased learning to rank (ULTR) tasks, recent work suggests that it suffers from a major limitation that could lead to its collapse in industry applications: the problem of logging policy confounding. Several potential solutions have even been proposed; however, the evaluation of these methods was mostly conducted using semi-synthetic simulation experiments. This paper bridges the gap between theory and practice by investigating the confounding problem on the largest real-world dataset, Baidu-ULTR. Our main contributions are threefold: 1) we s

Negative / Null Result ReportOpen accessComputer Science

Automatic Reviewers Fail to Detect Faulty Reasoning in Research Papers: A New Counterfactual Evaluation Framework

Nils Dycke, Iryna Gurevych · 2025 · arXiv

Large Language Models (LLMs) have great potential to accelerate and support scholarly peer review and are increasingly used as fully automatic review generators (ARGs). However, potential biases and systematic errors may pose significant risks to scientific integrity; understanding the specific capabilities and limitations of state-of-the-art ARGs is essential. We focus on a core reviewing skill that underpins high-quality peer review: detecting faulty research logic. This involves evaluating the internal consistency between a paper's results, interpretations, and claims. We present a fully au

Negative / Null Result ReportOpen accessComputer Science

A Practical Approach to using Supervised Machine Learning Models to Classify Aviation Safety Occurrences

Bryan Y. Siow · 2025 · arXiv

This paper describes a practical approach of using supervised machine learning (ML) models to assist safety investigators to classify aviation occurrences into either incident or serious incident categories. Our implementation currently deployed as a ML web application is trained on a labelled dataset derived from publicly available aviation investigation reports. A selection of five supervised learning models (Support Vector Machine, Logistic Regression, Random Forest Classifier, XGBoost and K-Nearest Neighbors) were evaluated. This paper showed the best performing ML algorithm was the Random

Negative / Null Result Report

Rumen by-pass soybean meal reduced ruminal ammonia but did not improve growth performance and nitrogen utilization in growing Hanwoo heifers

Joonpyo Oh, Dae Kyum Yoo, Si Woo Jeong et al. · 2025 · Animal Bioscience

Objective: The effects of heat-treated soybean meal (SBM) and citric acid (HCSBM) on the growth performance, rumen fermentation, blood metabolites, nutrient digestibility, and nitrogen (N) utilization were evaluated in growing Hanwoo…

View details →DOI: 10.5713/ab.24.0860
Negative / Null Result Report

Additional Decitabine Did Not Improve Outcomes of Elder Acute Myeloid Leukemia Patients Based on Microtransplantation with Cytarabine and Anthracycline Chemotherapy

Kaixun Hu, Yajing Huang, Huisheng Ai et al. · 2015 · Blood

Abstract Acute myeloid leukemia (AML) of older patients is an aggressive malignancy. Despite decitabine is performed some clinic trials in these patients, however there is little data on efficacy and is more controversial on it. Recent…

View details →DOI: 10.1182/blood.v126.23.1318.1318
Negative / Null Result Report

Did multiagent chemotherapy improve clinical outcomes of advanced pancreatic cancer? A single center experience of 408 cases.

Yousuke Nakai, Hiroyuki Isayama, Kazunaga Ishigaki et al. · 2016 · Journal of Clinical Oncology

293 Background: We previously reported the introduction of S-1 improved overall survival (OS) in advanced pancreatic cancer (PC), but in a pooled analysis of 3 RCTs, a combination of gemcitabine and S-1 (GS) improved OS in locally advanced…

View details →DOI: 10.1200/jco.2016.34.4_suppl.293
Negative / Null Result Report

Delaying Shoulder Motion and Strengthening and Increasing Achilles Allograft Thickness for Glenoid Resurfacing Did Not Improve the Outcome for a 30-Year-Old Patient with Postarthroscopic Glenohumeral Chondrolysis

John G. Skedros, Tanner R. Henrie, Chad S. Mears · 2014 · Case Reports in Orthopedics

Although interposition soft-tissue (biologic) resurfacing of the glenoid with humeral hemiarthroplasty has been considered an option for end-stage glenohumeral arthritis, the results of this procedure are highly unsatisfactory in patients…

View details →DOI: 10.1155/2014/517801
Negative / Null Result Report

Postoperative Doxycycline Did Not Improve Early Postoperative Outcomes in Hip Arthroscopy Patients: A Retrospective Cohort Study

Zeeshan M. Akhtar, Emily R. Hunt, Brooks N. Platt et al. · 2021 · The Journal of Hip Surgery

Abstract Doxycycline has been shown to reduce fibroblast activity in the treatment of multiple pathologies, and was utilized as part of the postoperative medication protocol to help prevent adhesions from developing after hip arthroscopy.…

View details →DOI: 10.1055/s-0041-1739456
Negative / Null Result Report

Did the 2017 wage increase improve job satisfaction of academic staff? A case study of the university of Nigeria, Nsukka

Abdullahi Abubakar, Boniface Denis Umoh · 2023 · Caleb International Journal of Development Studies

Many employees are merely holding on to their current jobs for lack of alternatives. Such staff members are no longer deriving satisfaction from their current jobs. Lack of satisfaction impinges on workers productivity and attitude to work…

View details →DOI: 10.26772/cijds-2023-06-01-06
Negative / Null Result Report

P0603 Early tumour necrosis factor inhibitor initiation is associated with increased persistence in Crohn’s Disease but not Ulcerative Colitis, whereas early ustekinumab, vedolizumab and tofacitinib did not improve persistence

B Gu, J Chetwood, A Pudipeddi et al. · 2026 · Journal of Crohn’s and Colitis

Abstract Background Emerging evidence suggests early initiation of advanced therapies (AT) may improve outcomes, but optimal timing remains unclear. We aimed to assess the impact of AT timing on persistence. Methods We interrogated the…

View details →DOI: 10.1093/ecco-jcc/jjaf231.784
Failed Experiment Report

The Novel Use of Hyperbaric Oxygen Therapy to Improve Umbilical Cord Blood Stem Cell Engraftment in Irradiated NOD/SCID Mice: What Did We Learn?

Omar S. Aljitawi, Jeff Radel, Bruce Kimler et al. · 2011 · Blood

Abstract Abstract 4695 Introduction: UCB is also an attractive stem cell source for transplantation because of the ease of procurement, the absence of donor risks, and reduced risk of transmissible infections. Unfortunately, outcomes of…

View details →DOI: 10.1182/blood.v118.21.4695.4695
Negative / Null Result Report

A Novel Honey Powder-Based Supplement Containing Carbohydrate and Protein Did Not Improve Endurance Performance in Recreationally Trained Cyclists

Taíse Toniazzo, Rafael de Almeida Azevedo, Tamires Nunes Oliveira et al. · 2025 · International Journal of Sport Nutrition and Exercise Metabolism

Sports supplements composed of carbohydrate and protein are widely used by endurance athletes and recreational practitioners, mostly aimed at improving performance. This study investigated the effect of a novel carbohydrate + protein honey…

View details →DOI: 10.1123/ijsnem.2025-0021
Negative / Null Result Report

Rapamycin adjuvant therapy did not improve the outcome of severe influenza virus infection in an experimental mouse model system

Ching-Tai Huang, Avijit Dutta, Tse-Ching Chen et al. · 2016 · The Journal of Immunology

Abstract The host immune system responds to influenza virus infection for eradication of the virus but the immune response associated inflammation causes tissue injury and damage to the host as well. Severe influenza with morbidity and…

View details →DOI: 10.4049/jimmunol.196.supp.76.21
Negative / Null Result ReportMedicine

Inhibitory Effects of Oxytocin on Jejunal Migrating Myoelectric Complex Activity in Fasted Rats: Role of Oxytocin and GLP-1 Receptors.

Balcı, Saltık, Aktemur et al. · 2026 · Life (Basel, Switzerland)

The migrating myoelectric complex (MMC) is the electrical basis of fasting small intestinal motility. Although oxytocin (OT) regulates gastrointestinal functions through oxytocin receptors (OTRs), its effect on jejunal MMC activity during…

View details →DOI: 10.3390/life16061029
Negative / Null Result Report

Utility of platelet indices as a diagnostic indicator of hemodynamically significant PDA in preterm infants: a comparative cross-sectional study

Samar Mahmoud Elbahy, Ola Galal Ali, Sara Soliman Ali et al. · 2024 · Egyptian Pediatric Association Gazette

Abstract Background Among preterm babies, patent ductus arteriosus (PDA) is a prevalent condition, and hemodynamically significant patent ductus arteriosus (hsPDA) constitutes an important problem that impacts their outcome. There has…

View details →DOI: 10.1186/s43054-024-00339-2
Negative / Null Result Report

OA09 Significant association between disease duration in axial spondyloarthritis and the occurrence of uveitis and inflammatory bowel disease, with no such association found for psoriasis

Brona Dinneen, Marcus Kenyon, Finbar O'Shea · 2024 · Rheumatology

Abstract Background/Aims Axial spondyloarthritis is a chronic inflammatory condition primarily impacting the spine and sacroiliac joints. In addition to spinal inflammation and peripheral symptoms, it frequently presents with…

View details →DOI: 10.1093/rheumatology/keae163.009
Negative / Null Result Report

PATHOLOGICAL AND MOLECULAR PARAMETERS SHOW NO SIGNIFICANT ASSOCIATION WITH RESIDUAL CANCER BURDEN IN BREAST CARCINOMA

Fishella Aprista Rahmanti, Willy Sandhika, Lusiani Tjandra · 2025 · Folia Medica Indonesiana

Residual Cancer Burden (RCB) is a validated scoring system that quantifies the amount of tumour remaining after neoadjuvant chemotherapy (NAC) for breast cancer, providing prognostic information beyond binary outcomes, such as pathologic…

View details →DOI: 10.65346/2599-056x.2407
Negative / Null Result Report

THE ASSOCIATION OF LONELINESS AND CHRONIC CLINICALLY SIGNIFICANT PAIN AMONG AFRICAN AMERICAN AND WHITE OLDER ADULTS

David Camacho, Denise Burnette, Maria P Aranda et al. · 2019 · Innovation in Aging

Abstract Loneliness and pain are significant public health problems in later life, yet limited research has examined how these factors interact among racially diverse older adults. Guided by the Biopsychosocial Model of Pain, we used data…

View details →DOI: 10.1093/geroni/igz038.2281
Negative / Null Result Report

The Association Between Significant Mitral Regurgitation and Atrial Fibrillation Recurrence Post-Ablation

Arni Gershman, Rivka Farkash, Amjad Abu-Salman et al. · 2025 · Journal of Clinical Medicine

Background: Atrial fibrillation (AF) is a common tachyarrhythmia associated with increased morbidity. AF frequently occurs alongside mitral regurgitation (MR). Although the impact of MR severity on AF is well proven, its effect on AF…

View details →DOI: 10.3390/jcm14207300
Negative / Null Result Report

Association between global longitudinal strain and coronary artery calcium in the diagnosis of significant coronary artery disease

M Shvydka, M Lutay, I Golikova · 2026 · European Heart Journal - Cardiovascular Imaging

Abstract Introduction Non-invasive diagnostic methods for coronary artery disease (CAD) are gaining increasing importance due to their accessibility, diagnostic value, safety, and cost-effectiveness. Both global longitudinal strain (GLS)…

View details →DOI: 10.1093/ehjci/jeaf367.070
Negative / Null Result Report

Significant Association between Sleep Deprivation and Somato Testicular Index: an experimental study on Albino Rats

Ameera Al-Humidi, Mohammed Abdulsalam · 2025 · Yemeni Journal for Medical Sciences

Background: Sleep deprivation is total or partial absence of sleep. It is a risk factor for many diseases including disorders of reproductive system. Objective: This study aimed to investigate the correlation between sleep deprivation and…

View details →DOI: 10.20428/yjms.v19i4.2793
Negative / Null Result Report

Prognostically significant peripheral retinal degenerations: Association with axial length, refraction, and age

A. V. Myagkov, A. S. Stoyukhina, E. V. Shibalko et al. · 2025 · The EYE GLAZ

Background. Peripheral retinal degeneration (PRD) is among the key risk factors for rhegmatogenous retinal detachment (RRD), particularly in patients with myopia. Despite the accumulated data, the threshold values of axial length and…

View details →DOI: 10.33791/2222-4408-2025-4-288-296
Negative / Null Result Report

Comparative analysis of dietary patterns and depression risk: significant inverse association with HEI-2015 and mediating role of BMI

Zicheng Wang, Lei Fang, Fachao Shi et al. · 2025 · Frontiers in Nutrition

Objective Depression is a severe global mental disorder closely associated with dietary habits. This study aimed to evaluate associations between four dietary patterns [assessed by Dietary Inflammatory Index (DII), Healthy Eating…

View details →DOI: 10.3389/fnut.2025.1680741
Negative / Null Result Report

Evaluation of the departmental inter-rater reliability when scoring thyroid nodules according to the British Thyroid Association Ultrasound-classification model: Is there significant disagreement?

Nabil Rtam · 2023 · Ultrasound

Introduction: The British Thyroid Association Ultrasound-classification is a risk stratification model which grades thyroid nodules in U2–5 based on their sonographic appearance. Existence of variability between the ultrasound operators…

View details →DOI: 10.1177/1742271x231215500
Negative / Null Result Report

Investigation of Chromosomal Abnormalities and AZF Microdeletions in Iranian Infertile Men and Their Significant Association

Narges Taheri, Mahzad Nasir Shalal, Mahdi Mazloom et al. · 2025 · Andrologia

Objective Chromosomal abnormalities participate in male infertility by affecting a variety of physiological functions including spermatogenesis, hormonal homoeostasis, and semen quality. The long arm of the Y chromosome has an important…

View details →DOI: 10.1155/and/6689096