Inhibiting the P2Y12 Receptor in Megakaryocytes and Platelets Suppresses Interferon-Associated Responses
Marcin A. Sowa; Haoyu Sun; Tricia T. Wang; Vitor W. Virginio; Florencia Schlamp; Hanane El Bannoudi; MacIntosh Cornwell; Hannah Bash · 2024 · JACC Basic to Translational Science
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
We investigated the impact of antiplatelet therapy on the megakaryocyte (MK) and platelet transcriptome. RNA-sequencing was performed on MKs treated with aspirin or P2Y12 inhibitor, platelets from healthy volunteers receiving aspirin or…
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Metadata source: OpenAlex · DOI 10.1016/j.jacbts.2024.05.014