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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19815 results in Negative / Null Result Report · page 164 of 661

Negative / Null Result Report

Rituxiamb Did Not Improve Clinical Outcomes In AIDS-Related Burkitt Lymphoma

Hideyuki Yamamoto, Shotaro Hagiwara, Yuki Kojima et al. · 2011 · Blood

Abstract Abstract 1629 Background: With the widespread use of highly active antiretroviral therapy (HAART), the prognosis of HIV infected subjects has been improved, even if with AIDS-related lymphoma. Burkitt lymphoma progresses very…

View details →DOI: 10.1182/blood.v118.21.1629.1629Cited by 2
Negative / Null Result Report

Ultrasound-guided supraclavicular nerve block for implantable port catheters: Does it show a significant difference in pain control?

Emre Can Çelebioğlu, Mehmet Sadık Bilgiç · 2021 · The Journal of Vascular Access

Background: Nerve blocks have been used for decades at head and neck region interventions and recently introduced as an alternative option for subcutaneous port implantation. This study aimed to compare two different local anesthesia…

View details →DOI: 10.1177/1129729820987358Cited by 2
Negative / Null Result Report

Rice yield in Costa Rican Central Pacific did not improve with a urease inhibitor

Ana Gabriela Pérez-Castillo, Weynner Giraldo-Sanclemente, Mayela Monge-Muñoz et al. · 2024 · Frontiers in Agronomy

Urea is widely used as nitrogen (N) source for rice fertilization in Costa Rica, despite its low efficiency linked to ammonia losses. To assess urea management alternatives, two field experiments were conducted in the Central Pacific…

View details →DOI: 10.3389/fagro.2024.1394143Cited by 2
Negative / Null Result Report

Variations in Polysomnographic Indices of Obstructive Sleep Apnea following Lingual Tonsil Hypertrophy Excision: Is the Difference Significant?

Ashraf Wahba, Khaled Abdelaal, Ayman Yehia et al. · 2022 · Medicina

Background and Objectives: Obstructive sleep apnea (OSA) is a sleep-related respiratory disorder that affects between 5% and 20% of the population. In obstructive sleep apnea, lingual tonsillar hypertrophy (LTH) has been suggested as a…

View details →DOI: 10.3390/medicina58050573Cited by 2
Negative / Null Result Report

Self-Determination Skills of College Students with Autism Spectrum Disorder (ASD)

Jacqueline Lubin, null null, null null et al. · 2020 · John Heinrichs Scholarly & Creative Activities Day

Research has shown there is a positive correlation between self-determination skills and quality of life of college students with autism spectrum disorder (ASD). The purpose of this literature review is to highlight research on…

View details →DOI: 10.58809/kenx6266Cited by 2
Negative / Null Result Report

Casp8p41: The Protean Mediator of Death in CD4 T-cells that Replicate HIV

Rahul Sampath, Nathan W. Cummins, Andrew D. Badley · 2016 · Journal of Cell Death

HIV cure is now the focus of intense research after Timothy Ray Brown (the Berlin patient) set the precedent of being the first and only person cured. A major barrier to achieving this goal on a meaningful scale is an elimination of the…

View details →DOI: 10.4137/jcd.s39872Cited by 2
Negative / Null Result Report

Dataset of replicate Apollo sample magnetizations bearing on impacts and absence of a long-lived lunar dynamo

Rory D. Cottrell, Tinghong Zhou, John A. Tarduno · 2024 · Scientific Data

Abstract The absence or presence of a lunar paleomagnetosphere is important because it bears directly on the volatile content of the regolith and exploration targets for Artemis and other missions to the Moon. Recent paleointensity study…

View details →DOI: 10.1038/s41597-024-03626-0Cited by 2
Negative / Null Result Report

Less risk of patellofemoral degeneration without significant clinical and survivorship difference for distal tibial tuberosity high tibial osteotomy compared to biplanar high tibial osteotomy over a mid-term follow-up

Ke Li, Hengbing Guo, Fenglong Sun et al. · 2024 · Journal of Orthopaedic Surgery

Purpose This study aims to compare the mid-term radiographic, clinical results and survivorship between distal tibial tuberosity high tibial osteotomy (DTT-HTO) and conventional biplanar medial open-wedge high tibial osteotomy (cOW-HTO).…

View details →DOI: 10.1177/10225536241273925Cited by 2
Negative / Null Result Report

Significant Differences and Experimental Designs Do Not Necessarily Imply Clinical Relevance: Effect Sizes and Causality Claims in Antidepressant Treatments

Iván Sánchez-Iglesias, Celia Martín-Aguilar · 2023 · Journal of Clinical Medicine

Clinical trials are the backbone of medical scientific research. However, this experimental strategy has some drawbacks. We focused on two issues: (a) The internal validity ensured by clinical trial procedures does not necessarily allow…

View details →DOI: 10.3390/jcm12093181Cited by 2
Negative / Null Result Report

A real life retrospective analysis of drug expenditure reveals no significant cost difference between infliximab and adalimumab in the treatment of adult crohn's disease: Figure 1

C A Lamb, M Price, M Robinson et al. · 2011 · Gut

Introduction The revised NICE guidance on the use of infliximab and adalimumab for the treatment of Crohn's disease, released in May 2010, has suggested biologics be prescribed as a planned therapy until treatment failure or until…

View details →DOI: 10.1136/gut.2011.239301.534Cited by 2
Negative / Null Result Report

Significant effect of SDS on the optimum operating temperature of ZnO nanosheets gas-sensitive materials

Hai Yu, Xiaoqi Yu, Chengyou Liu et al. · 2022 · The European Physical Journal Applied Physics

Many methods have been used to reduce the operational energy consumption of ZnO gas-sensitive material effectively. In this paper, different morphologies of ZnO nanomaterials are prepared in the anionic hydrophilic surfactant sodium lauryl…

View details →DOI: 10.1051/epjap/2021210247Cited by 2
Negative / Null Result Report

The small impact of p-hacking marginally significant results on the meta-analytic estimation of effect size

Juan Botella, Manuel Suero, Juan I. Durán et al. · 2021 · Anales de Psicología

La etiqueta p-hacking (pH) se refiere a un conjunto de prácticas oportunistas destinadas a hacer que sean significativos algunos valores p que deberían ser no significativos. Algunos han argumentado que debemos prevenir y luchar contra el…

View details →DOI: 10.6018/analesps.433051Cited by 2
Negative / Null Result Report

ANALISIS KEMAMPUAN CALON GURU DALAM MENGEMBANGKAN MEDIA PEMBELAJARAN

Ines Tasya Jadidah, Eby Sania Awalia, Althaafi Abdillah et al. · 2023 · SIGNIFICANT : Journal Of Research And Multidisciplinary

Tujuan penelitian ini dilakukan agar dapat menganalisa kemampuan calon guru dalam mengembangkan media pembelajaran. Penelitian ini menggunakan penelitian kualitatif deskrpitif yang intrumen nya berupa observasi untuk memperoleh suatu…

View details →DOI: 10.62668/significant.v1i02.658Cited by 2
Negative / Null Result Report

Abstract PD05-08: Lack of Significant Association between CYP2D6 Polymorphisms and Clinical Outcomes of Adjuvnt Tamoxifen Therapy

H Kim, H-C Shin, CK Yom et al. · 2010 · Cancer Research

Abstract Purpose: CYP2D6 variant alleles have been suspected to influence on the clinical efficacy of tamoxifen because CYP2D6 is an enzyme which metabolizes tamoxifen into its active forms, endoxifen and 4-hydroxytomoxifen. This study was…

View details →DOI: 10.1158/0008-5472.sabcs10-pd05-08Cited by 2
Negative / Null Result Report

Hippocampal size did not differ between epileptic and non-epileptic dogs using volumetric and subjective methods

Borbála A. Lőrincz, Agustina Anson, Stephan Handschuh et al. · 2021 · Acta Veterinaria Hungarica

Abstract Hippocampal changes in epilepsy may manifest as hippocampal atrophy/sclerosis. A recent human study suggests that the demonstration of hippocampal volume loss is more reliable using quantitative evaluation methods. The aim of the…

View details →DOI: 10.1556/004.2021.00006Cited by 2
Negative / Null Result Report

Did an Intervention Programme Aimed at Strengthening the Maternal and Child Health Services in Nigeria Improve the Completeness of Routine Health Data Within the Health Management Information System?

Benjamin Uzochukwu, Tolib Mirzoev, Chinyere Okeke et al. · 2020 · International Journal of Health Policy and Management

Background: During 2012-2015, the Federal Government of Nigeria launched the Subsidy Reinvestment and Empowerment Programme, a health system strengthening (HSS) programme with a Maternal and Child Health component (Subsidy Reinvestment and…

View details →DOI: 10.34172/ijhpm.2020.226Cited by 2
Negative / Null Result Report

A single session of a beach volleyball exergame did not improve state anxiety level in healthy adult women

Vinnycius Nunes de Oliveira, Ricardo Borges Viana, João Victor Rosa de Freitas et al. · 2024 · BMC Sports Science, Medicine and Rehabilitation

Abstract This study evaluated the acute effect of the exergame Kinect Sports ® beach volleyball on state anxiety level in adult women. Thirty healthy adult women (age: 21 [4] years, body mass: 54.70 [19.50] kg, height: 1.61 ± 0.05 m, and…

View details →DOI: 10.1186/s13102-024-00859-9Cited by 2
Negative / Null Result Report

Abstract 16996: Controlled Pauses (“Stutter”) CPR Did Not Improve ROSC or 4-hour Survival in a Porcine Model of VF-induced Cardiac Arrest

Alexander Esibov, Tyson G Taylor, Sharon B Melnick et al. · 2015 · Circulation

Introduction: Ischemic post-conditioning (IPC) has shown promise in mitigating ischemia-reperfusion injury. Controlled pauses during CPR (CP-CPR) following cardiac arrest (CA) and prolonged downtime may help invoke IPC mechanisms and have…

View details →DOI: 10.1161/circ.132.suppl_3.16996Cited by 2
Negative / Null Result Report

When biology takes over: TV formats like The Bachelor and The Bachelorette confirm evolutionary theories of partner selection

Alexandra Lenhard, Marie-Pierre Minten, Wolfgang Lenhard · 2023 · Frontiers in Psychology

Introduction In this study, we investigated the impact of age on mate selection preferences in males and females, and explored how the formation and duration of committed relationships depend on the sex of the person making the selection.…

View details →DOI: 10.3389/fpsyg.2023.1219915Cited by 2
Negative / Null Result Report

Diet composition of the lizard Lacerta viridis (Laurenti, 1768) (Reptilia: Lacertidae) in Bulgaria confirm its generalistic feeding behaviour

Emiliya Vacheva, Borislav Naumov · 2024 · Historia naturalis bulgarica

The eastern green lizard (Lacerta viridis) is a mostly insectivorous species, based on multiple studies from across its range. However, for Bulgaria the published data of such kind are limited to five publications. We investigated faecal…

View details →DOI: 10.48027/hnb.46.071Cited by 2
Negative / Null Result Report

Lichen sclerosus et atrophicus and allergic contact dermatitis: A significant association

Antonella Tammaro, Francesca Magri, Chiara Iacovino et al. · 2019 · Journal of Cosmetic Dermatology

Summary Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory skin disease of unknown etiology. It mainly affects the anogenital area, while the extragenital involvement is uncommon. It manifests as pale, ivory‐colored lesions and…

View details →DOI: 10.1111/jocd.12915Cited by 2
Negative / Null Result Report

A medication-wide association study to identify medications associated with incident clinically significant diabetic retinopathy

Ruilin Xiong, Wei Wang, Xianwen Shang et al. · 2023 · Therapeutic Advances in Ophthalmology

Background: Diabetic retinopathy, a common microvascular complication of diabetes mellitus, is one of the leading causes of vision loss worldwide. Although some oral drugs have been suggested to affect the risk of diabetic retinopathy,…

View details →DOI: 10.1177/25158414221139002Cited by 2
Negative / Null Result Report

No Significant Association Between Vitamin C Supplements and Frailty in Korean Older Adults: A Cross-Sectional Analysis of the 2018–2019 Korea National Health and Nutrition Examination Survey

Seung Guk Park, Hyoeun Kim · 2025 · Nutrients

Background/Objectives: The association between vitamin C intake and frailty among older adults remains unclear, and evidence from Asian populations is limited. Using nationally representative data, we aimed to examine whether vitamin C…

View details →DOI: 10.3390/nu17182977Cited by 2
Negative / Null Result Report

Conventional machine learning-based prediction models did not outperform the International IgA Nephropathy Prediction Tool

Sehoon Park, Yisak Kim, Chung Hee Baek et al. · 2025 · Kidney Research and Clinical Practice

Background: Immunoglobulin A nephropathy (IgAN) is a major cause of end-stage kidney disease (ESKD). The International IgA Nephropathy Prediction Tool (IIgAN-PT) predicts IgAN prognosis, but improvement in the prediction performance using…

View details →DOI: 10.23876/j.krcp.23.212Cited by 2
Negative / Null Result Report

TESS Data do not Confirm Gravity Modes in the RR Lyrae Star HH Puppis

Tom Love · 2025 · Research Notes of the AAS

Abstract A recent study found pulsation frequencies in the RR Lyrae star HH Puppis that were identified as gravity modes, and argued that this phenomenon could explain the Blazhko effect in which pulsations of RR Lyrae stars undergo long…

View details →DOI: 10.3847/2515-5172/adfe64Cited by 2
Negative / Null Result Report

Significant association between IL-18 and OCT4 gene polymorphisms in susceptibility and clinical characteristics of prostate cancer*

Shaojun Nong, Yangbo Guan, Zhiwei Wang et al. · 2019 · Oncology and Translational Medicine

Abstract Objective Recent studies have shown abnormal expression of octamer-binding transcription factor 4 (OCT4) and interleukin-18 (IL-18) to be related to cancer. However, the molecular mechanisms by which the IL-18 and OCT4 gene…

View details →DOI: 10.1007/s10330-019-0342-2Cited by 2
Negative / Null Result Report

Adaptive enhancement design of non-significant regions of a Wushu action 3D image based on the symmetric difference algorithm

Chao Zhao, Bing Li, KaiYuan Guo · 2023 · Mathematical Biosciences and Engineering

The recognition of martial arts movements with the aid of computers has become crucial because of the vigorous promotion of martial arts education in schools in China to support the national essence and the inclusion of…

View details →DOI: 10.3934/mbe.2023662Cited by 2