Cetuximab Reduces the Accumulation of Radiolabeled Bevacizumab in Cancer Xenografts without Decreasing VEGF Expression
Sandra Heskamp; Otto C. Boerman; Janneke D.M. Molkenboer‐Kuenen; Fred C.G.J. Sweep; Anneke Geurts‐Moespot; Mallory S. Engelhardt; Winette T.A. van der Graaf; Wim J.G. Oyen · 2014 · Molecular Pharmaceutics
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
The finding, in one line
“However, in advanced colorectal cancer, addition of cetuximab to chemotherapy with bevacizumab did not improve survival.”
Abstract (excerpt)
Bevacizumab and cetuximab are approved for the treatment of cancer. However, in advanced colorectal cancer, addition of cetuximab to chemotherapy with bevacizumab did not improve survival. The reason for the lack of activity remains…
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WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: OpenAlex · DOI 10.1021/mp500460g