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Negative / Null Result ReportOpen accessAgricultural and Biological Sciences· cited by 9

Ecology and spread of the North American H5N1 epizootic

Lambodhar Damodaran; Anna S. Jaeger; Louise H. Moncla · 2025 · Nature

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Abstract

Abstract Since late 2021, a panzootic of highly pathogenic H5N1 has devastated wild birds, agriculture and mammals. Here an analysis of 1,818 haemagglutinin sequences from wild birds, domestic birds and mammals reveals that the North American panzootic was driven by around nine introductions into the Atlantic and Pacific flyways, followed by rapid dissemination through wild, migratory birds. Transmission was primarily driven by Anseriformes, while non-canonical species acted as dead-end hosts. In contrast to the epizootic of 2015 (refs. 1,2 ), outbreaks in domestic birds were driven by around

Abstract by Lambodhar Damodaran; Anna S. Jaeger; Louise H. Moncla, Nature (2025) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.1038/s41586-025-09737-x