Negative / Null Result ReportOpen accessMedicine
Shih-Chun Chang, Chi-Ming Tang, Puo‐Hsien Le et al. · 2021 · Cancers
Whether gastric adenocarcinoma (GC) patients with adjacent organ invasion (T4b) benefit from aggressive surgery involving pancreatic resection (PR) remains unclear. This study aimed to clarify the impact of PR on survival in patients with locally advanced resectable GC. Between 1995 and 2017, patients with locally advanced GC undergoing radical-intent gastrectomy with and without PR were enrolled and stratified into four groups: group 1 (G1), pT4b without pancreatic resection (PR); group 2 (G2), pT4b with PR; group 3 (G3), positive duodenal margins without Whipple’s operation; and group 4 (G4)
View details →DOI: 10.3390/cancers13061289Cited by 12 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Valeriy Timofeyev, C. A. Porter, Dipika Tuteja et al. · 2010 · American Journal of Physiology-Heart and Circulatory Physiology
Adenylyl cyclase (AC) is the principal effector molecule in the β-adrenergic receptor pathway. AC(V) and AC(VI) are the two predominant isoforms in mammalian cardiac myocytes. The disparate roles among AC isoforms in cardiac hypertrophy…
View details →DOI: 10.1152/ajpheart.01208.2009Cited by 12 Negative / Null Result ReportOpen accessEngineering
Christoph Leo, Maria C. Rizzi, N M Bos et al. · 2021 · Frontiers in Bioengineering and Biotechnology
This study has analyzed sex-specific differences in pedestrian and cyclist accidents involving passenger cars. The most frequently injured body regions, types of injuries, which show sex-specific differences and the general accident parameters of females and males were compared. Accident data from three different European countries (Austria, Netherlands, Sweden) were analyzed. The current analysis shows that for both, females and males, pedestrian and cyclist injuries are sustained mainly to the body regions head, thorax, upper extremities and lower extremities. The results show that the odds
View details →DOI: 10.3389/fbioe.2021.677952Cited by 12 Negative / Null Result ReportOpen accessMedicine
Fabrizio Ricci, Franz–Josef Neumann, Nicole Rübsamen et al. · 2022 · Frontiers in Cardiovascular Medicine
Background The instant, single-sampling rule-out of acute myocardial infarction (AMI) is still an unmet clinical need. We aimed at testing and comparing diagnostic performance and prognostic value of two different single-sampling biomarker strategies for the instant rule-out of AMI. Methods From the Biomarkers in Acute Cardiac Care (BACC) cohort, we recruited consecutive patients with acute chest pain and suspected AMI presenting to the Emergency Department of the University Medical Center Hamburg-Eppendorf, Hamburg, Germany. We compared safety, effectiveness and 12-month incidence of the comp
View details →DOI: 10.3389/fcvm.2022.895421Cited by 12 Negative / Null Result Report
Oleh V. Lushchak, Dmytro V. Gospodaryov, Ihor S. Yurkevych et al. · 2015 · Archives of Insect Biochemistry and Physiology
Aging is often associated with accumulation of oxidative damage in proteins and lipids. However, some studies do not support this view, raising the question of whether high levels of oxidative damage are associated with lifespan. In the…
View details →DOI: 10.1002/arch.21308Cited by 12 Negative / Null Result ReportOpen accessMedicine
András Komócsi, Dániel Aradi, Tibor Szük et al. · 2018 · The American Journal of Cardiology
Evidence is conflicting regarding the clinical benefits of selecting P2Y12 inhibitors based on platelet function testing (PFT). Between March 1, 2013 and March 1, 2014, we collected clinical characteristics and platelet function data in a…
View details →DOI: 10.1016/j.amjcard.2018.01.032Cited by 12 Negative / Null Result ReportOpen accessMedicine
Magnus Lindskog, Anna Laurell, Anders Kjellman et al. · 2022 · European Urology Open Science
Background: The prognosis of patients with synchronous metastatic renal cell carcinoma (mRCC) is poor. Whereas single-agent tyrosine kinase inhibition (TKI) is clearly insufficient, the effects can be enhanced by combinations with immune checkpoint inhibitors. Innovative treatment options combining TKI and other immune-stimulating agents could prove beneficial. Objective: To evaluate the clinical effects on metastatic disease when two doses of allogeneic monocyte-derived dendritic cells (ilixadencel) are administrated intratumorally followed by nephrectomy and treatment with sunitinib compared
View details →DOI: 10.1016/j.euros.2022.03.012Cited by 12 Negative / Null Result ReportOpen accessNeuroscience
Susanne Clinch, Stacie Hudgens, Elizabeth Gibbons et al. · 2023 · Patient Related Outcome Measures
Purpose: Adaptive Behavior Scale is often used in autism spectrum disorder (ASD) trials. The Adaptive Behavior Composite Score (VABS-ABC) is the standardized overall score (the average of the Socialization, Communication and Daily Living…
View details →DOI: 10.2147/prom.s385542Cited by 12 Negative / Null Result ReportOpen accessMedicine
Helen L. Reeves, John Reicher, Georgia Priona et al. · 2022 · Frontline Gastroenterology
Objective: Hepatocellular carcinoma (HCC) deaths are rising alarmingly. Many patients are unsuitable for available therapies. Poor response rates further hamper outcomes for those that are. Selective internal radiation therapy (SIRT) offers hope, although which patients benefit over standard approaches remains unclear. Design/method: As a quality/service improvement, we audited consecutive patients treated with SIRT (2015-2020) by the Newcastle upon Tyne Hospitals National Health Service Foundation Trust HCC multidisciplinary team. Indications, Barcelona clinic liver cancer (BCLC) stage, treat
View details →DOI: 10.1136/flgastro-2022-102137Cited by 12 Negative / Null Result ReportOpen accessMedicine
Ethan S. Lindgren, Onur Çil, A. S. Verkman et al. · 2022 · Current Ophthalmology Reports
Purpose of Review: To review the role of ocular surface epithelial (corneal and conjunctival) ion transporters in the pathogenesis and treatment of dry eye disease (DED). Recent Findings: Currently, anti-inflammatory agents are the mainstay of DED treatment, though there are several agents in development that target ion transport proteins on the ocular surface, acting by pro-secretory or anti-absorptive mechanisms to increase the tear fluid Film volume. Activation or inhibition of selected ion transporters can alter tear fluid osmolality, driving water transport onto the ocular surface via osm
View details →DOI: 10.1007/s40135-022-00295-3Cited by 12 Negative / Null Result Report
Jonas Ziegenhorn, Julia Kirschberg, Markus Heinecke et al. · 2024 · Knee Surgery, Sports Traumatology, Arthroscopy
Abstract Purpose The purpose of this study was to find out whether the torsions of the femur and tibia are dependent on the coronal plane alignment of the knee (CPAK) type. Methods Five hundred patients (1000 legs) were included, who…
View details →DOI: 10.1002/ksa.12149Cited by 12 Negative / Null Result ReportOpen accessMedicine
Brian Hitsman, George D. Papandonatos, Jackie K. Gollan et al. · 2023 · Addiction
BACKGROUND AND AIMS: Treatment of depression-related psychological factors related to smoking behavior may improve rates of cessation among adults with major depressive disorder (MDD). This study measured the efficacy and safety of 12…
View details →DOI: 10.1111/add.16209Cited by 12 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
David García Alonso, Ignacio Buesa, Luis Flor et al. · 2025 · Frontiers in Plant Science
The intensification of drought conditions due to climate change poses a major challenge to sustainable grape production. Rootstocks are essential in supporting grapevine water uptake and drought resilience; however, their physiological responses to water stress are not fully understood. Under the hypothesis that root morphology and anatomy may be key traits in grapevine tolerance to water deficit, this study aimed to investigate these traits across diverse rootstocks under progressive water deficit and recovery phases. Thirteen genotypes, including commercial rootstocks and recently bred RG-se
View details →DOI: 10.3389/fpls.2025.1541523Cited by 12 Negative / Null Result ReportOpen accessEnvironmental Science
Catherine S. Jarnevich, Helen R. Sofaer, Pairsa Belamaric et al. · 2022 · NeoBiota
Aim : Species distribution models can guide invasive species prevention and management by characterizing invasion risk across space. However, extrapolation and transferability issues pose challenges for developing useful models for invasive species. Previous work has emphasized the importance of including all available occurrences in model estimation, but managers attuned to local processes may be skeptical of models based on a broad spatial extent if they suspect the captured responses reflect those of other regions where data are more numerous. We asked whether species distribution models fo
View details →DOI: 10.3897/neobiota.77.86364Cited by 12 Negative / Null Result ReportOpen accessMedicine
Alessandro Rabiolo, Federico Fantaguzzi, Riccardo Sacconi et al. · 2021 · Translational Vision Science & Technology
Purpose: Compare the ability of peripapillary and macular structural parameters, vascular parameters, and their integration to discriminate among glaucoma, suspected glaucoma (GS), and healthy controls (HCs). Methods: In this study, 196…
View details →DOI: 10.1167/tvst.10.14.20Cited by 12 Negative / Null Result Report
Suman Prasad, Triptish Bhatia, Prachi Kukshal et al. · 2017 · npj Schizophrenia
Abstract Schizophrenia is a chronic, severe, heritable disorder. Genome-wide association studies, conducted predominantly among Caucasians, have indicated > 100 risk alleles, with most significant SNPs on chromosome 6. There is growing…
View details →DOI: 10.1038/s41537-017-0030-8Cited by 12 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Marlee R. Labroo, Jessica Rutkoski · 2022 · BMC Genomics
BACKGROUND: Recurrent selection is a foundational breeding method for quantitative trait improvement. It typically features rapid breeding cycles that can lead to high rates of genetic gain. Usually, generations are discrete in recurrent selection, which means that breeding candidates are evaluated and considered for selection for only one cycle. Alternately, generations can overlap, with breeding candidates considered for selection as parents for multiple cycles. With recurrent genomic selection but not phenotypic selection, candidates can be re-evaluated by using genomic estimated breeding v
View details →DOI: 10.1186/s12864-022-08929-3Cited by 12 Negative / Null Result ReportOpen accessNeuroscience
Daniel Griffiths-King, Amanda Wood, Jan Novák · 2023 · Scientific Reports
Brain development is regularly studied using structural MRI. Recently, studies have used a combination of statistical learning and large-scale imaging databases of healthy children to predict an individual's age from structural MRI. This data-driven, predicted 'Brainage' typically differs from the subjects chronological age, with this difference a potential measure of individual difference. Few studies have leveraged higher-order or connectomic representations of structural MRI data for this Brainage approach. We leveraged morphometric similarity as a network-level approach to structural MRI t
View details →DOI: 10.1038/s41598-023-42414-5Cited by 12 Negative / Null Result ReportOpen accessEnvironmental Science
Daniel Flores-Orozco, David B. Levin, Ayush Kumar et al. · 2023 · Environmental Advances
This study evaluated the long-term effects of mesophilic (MAD) and thermophilic (TAD) anaerobic digestion on the fate and evolution of antimicrobial resistance genes (ARGs) and mobile genetic elements (MGEs) in cattle manure following a…
View details →DOI: 10.1016/j.envadv.2023.100472Cited by 12 Negative / Null Result ReportOpen accessNeuroscience
Nicole T. Ong, Jamie Hawke, Nicola J. Hodges · 2019 · Brain Sciences
We evaluated if and how success perceptions, through target size manipulations, impact processes related to motor learning. This work was based on recent literature suggesting that expectations and self-efficacy exert a direct impact on learning. We measured arousal, kinematics, learner expectancies, motivation, and outcomes in a dart-throwing task. Novices (n = 29) were assigned to either a “Large-target” (horizontal target, 10-cm high) or “Small-target” (2-cm high) group for practice (t = 90), and both groups completed 24-h retention tests. The Small-target group took longer to plan and proc
View details →DOI: 10.3390/brainsci9050119Cited by 12 Negative / Null Result ReportOpen accessDentistry
Ignazio La Mantia, Claudio Andaloro, Pasquale Gianluca Albanese et al. · 2026 · EuroMediterranean Biomedical Journal
Allergic rhinitis is a common problem increasing greatly over the past three decades. Several studies have found a possible link between dyslipidem ia and allergic disease but the relating causal mechanisms remain elusive. The aim of this…
View details →DOI: 10.3269/1970-5492.2017.12.30Cited by 12 Negative / Null Result ReportEarth and Planetary Sciences
David John Gagne, Amy McGovern, Jeffrey B. Basara et al. · 2012 · Journal of Applied Meteorology and Climatology
Abstract Oklahoma Mesonet surface data and North American Regional Reanalysis data were integrated with the tracks of over 900 tornadic and nontornadic supercell thunderstorms in Oklahoma from 1994 to 2003 to observe the evolution of…
View details →DOI: 10.1175/jamc-d-11-060.1Cited by 12 Negative / Null Result Report
Alexis Vrachimis, Joachim Gerss, Maren Stoyke et al. · 2014 · Clinical Endocrinology
Summary Objective The seventh edition of the American Joint Committee on Cancer ( AJCC ) has more detailed staging categories for differentiated thyroid cancer ( DTC ) than the fifth edition. The aim was to compare potential alterations in…
View details →DOI: 10.1111/cen.12405Cited by 12 Negative / Null Result ReportComputer Science
Subrata Datta, Kalyani Mali · 2021
Traditional support-confidence framework based association rule mining approaches often generate huge number of rules including the insignificant ones. These insignificant association rules are useless in knowledge discovery. One of the…
View details →DOI: 10.1109/iciccs51141.2021.9432237Cited by 12 Negative / Null Result ReportOpen accessDecision Sciences
Michael Kossmeier, Georg Heinze · 2018 · Transplant International
Citations are widely used for measuring scientific impact. The goal of the present study was to predict citation counts of manuscripts submitted to Transplant International (TI) in the two calendar years following publication. We…
View details →DOI: 10.1111/tri.13292Cited by 12 Negative / Null Result ReportOpen accessComputer Science
Vincent Adegoke, Daqing Chen, Ebad Banissi et al. · 2017
In this paper, several ensemble cancer survivability predictive models are presented and tested based on three variants of AdaBoost algorithm. In the models we used Random Forest, Radial Basis Function Network and Neural Network algorithms…
View details →DOI: 10.1109/sst.2017.8188699Cited by 12 Negative / Null Result ReportOpen accessMedicine
Prajakta Paritekar, Akshay Nayak, Y Umesh et al. · 2022 · Indian Journal of Ophthalmology
Purpose: To compare the efficacy of Kane formula with Sanders Retzlaff Kraff/Theoretical (SRK/T) and Barrett Universal II in predicting intraocular lens (IOL) power in Indian eyes. Methods: This retrospective study conducted in a tertiary…
View details →DOI: 10.4103/ijo.ijo_2014_21Cited by 12 Negative / Null Result ReportNeuroscience
Yanyan Yang, Hongan Wang, XU Hai-ping et al. · 2023 · Autism Research
The early start Denver model (ESDM) has been extensively studied as a promising early intervention approach for young children with autism spectrum disorder (ASD). Various methodological drawbacks from earlier ESDM investigations must be…
View details →DOI: 10.1002/aur.3006Cited by 12 Negative / Null Result ReportOpen accessMedicine
M.a Cruces Souto-Gallardo, Arturo Jiménez–Cruz, Montserrat Bacardí‐Gascón · 2026 · Archivos Latinoamericanos de Nutrición
The aim of this study was to evaluate the ability of parents to estimate the weight status of preschool children attending the Instituto Mexicano del Seguro Social (IMSS) day-care centers using three different tools. A total of 100…
View details →DOI: 10.37527/2011.61.4.007Cited by 12 Negative / Null Result ReportOpen accessSocial Sciences
Laura Macchi, Francesco Poli, Laura Caravona et al. · 2019 · Europe’s Journal of Psychology
The previous research attempts to reduce the influence of the belief bias on deductive thinking have often been unsuccessful and, when they succeeded, they failed to replicate. In this paper, we propose a new way to see an old problem. Instead of considering the analytical abilities of the respondent, we focus on the communicative characteristics of the experimental task. By changing the pragmatics into play through a subtle manipulation of the instruction of the syllogism problem, we obtained a strong improvement in the accuracy of the performance in both untrained and trained in logic respon
View details →DOI: 10.5964/ejop.v15i3.1794Cited by 12 