Home-Based Prehabilitation for Older Surgical Patients With Frailty
Daniel I. McIsaac; Susan M. Lee; Dean Fergusson; Chelsia Gillis; Rachel G. Khadaroo; Amanda Meliambro; John Muscedere; Antoine Eskander · 2025 · JAMA Surgery
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Importance: Explanatory trials suggest that prehabilitation has efficacy in improving surgical outcomes. The effectiveness of offering home-based prehabilitation across multiple centers and for older adults with frailty remains unknown. Objective: To evaluate the effectiveness of offering coach-supported, home-based prehabilitation to older surgical patients with frailty. Design, Setting, and Participants: This study is a pragmatic, parallel-arm, multicenter randomized clinical trial with embedded qualitative assessment. Clinicians and assessors were fully blinded; participants were partially
Abstract by Daniel I. McIsaac; Susan M. Lee; Dean Fergusson; Chelsia Gillis; Rachel G. Khadaroo; Amanda Meliambro; John Muscedere; Antoine Eskander, JAMA Surgery (2025) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1001/jamasurg.2025.5288