A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21697 results · page 129 of 724
Sandeep M. Nayak, Bilal A. Bari, David B. Yaden et al. · 2022 · Psychedelic Medicine
Objectives: To perform a Bayesian reanalysis of a recent trial of psilocybin (COMP360) versus escitalopram for Major Depressive Disorder (MDD) in order to provide a more informative interpretation of the indeterminate outcome of a previous…
Allegra Niggeler, Jens Tetens, Anna Stäuble et al. · 2017 · Animal Genetics
Footrot is one of the most important causes of lameness in global sheep populations and is characterized by a bacterial infection of the interdigital skin. As a multifactorial disease, its clinical representation depends not only on…
Geri R. Donenberg, Jessica Fitts, Charles Ingabire et al. · 2022 · JAIDS Journal of Acquired Immune Deficiency Syndromes
Background: Adolescents living with HIV have elevated mental distress and suboptimal antiretroviral therapy (ART) adherence. Setting: Two urban clinics in Kigali, Rwanda. Methods: A 2-arm individual randomized controlled trial compared…
Aurélie Ferrer, Dominique Mazzi, Silvia Dorn · 2014 · Entomologia Experimentalis et Applicata
Abstract Acclimation to a particular environment may provide organisms with advantages in that environment. In species with multiple generations per year, acclimation may cause life‐history traits to vary with season and between…
Liang Chih Liu, Su Chen, Hwei Chung Wang et al. · 2011 · PubMed
AIM: Japanese and American groups reported that single nucleotide variation of caveolin-1 gene (CAV1) plays an important role in breast cancer risk. The aim of this study was to evaluate the association of six polymorphic genotypes of…
Marcos Christiano Lange, Viviane Flumignan Zétola, Élcio J Piovesan et al. · 2010 · Journal of Neuroimaging
ABSTRACT BACKGROUND AND PURPOSE Agitated saline solution (AS) is the contrast agent (CA) of choice for the diagnosis of right‐to‐left shunt (RLS). The aim of this study was to compare AS to AS with blood (ASb) in the diagnosis and…
Heather M. Wasser, Amanda L. Thompson, Chirayath M. Suchindran et al. · 2020 · BMC Pediatrics
Abstract Background Non-Hispanic black (NHB) infants are twice as likely as non-Hispanic white infants to experience rapid weight gain in the first 6 months, yet few trials have targeted this population. The current study tests the…
Georg Hauer, Nina Hörlesberger, Sebastian Klim et al. · 2020 · Knee Surgery, Sports Traumatology, Arthroscopy
Abstract Purpose The purpose of this study was to compare the clinical and functional outcome scores following total knee arthroplasty (TKA) with two different systems. The hypothesis was that there is a difference between patients…
Michael J. Serra · 2021 · Frontiers in Psychology
People demonstrate a memory advantage for animate (living) concepts over inanimate (nonliving) concepts in a variety of memory tasks, including free recall, but we do not know the mechanism(s) that produces this effect. We compared the…
Susan Ellison · 2015 · PoLAR: Political and Legal Anthropology Review
In the wake of a massive 2003 uprising in El Alto, Bolivia, U.S. democracy assistance programs targeted the city, promising to address Alteños’ frustration with democratic institutions and to teach deliberative democratic skills. In this…
Christie Lynn Martin · 2015 · School Science and Mathematics
In this study, I examine how using a writers' workshop model in mathematics creates a space for students to write about their mathematical thinking and problem solving and how their writing impacts instruction. This case study of one…
Erik Hansen, Gerda Vaitkunaite, Johannes Schneider et al. · 2023 · Lubricants
While the modification of surface contacts offers significant potential for friction reduction, obtaining an underlying consistent friction behaviour of real-life experiments and virtual simulations is still an ongoing challenge. In…
Vaiva Petrylė · 2017 · Ekonomika
The concept of a country’s competitiveness still does not have a clear and straightforward meaning and remains ambiguous. Different economists stress various aspects of the concept and use a number of different methods to evaluate how…
A. S. Santoro, M. G. Cooper, A. Cheng · 2012 · Anaesthesia and Intensive Care
A ‘can't intubate, can't oxygenate’ scenario in a child is fortunately extremely rare. We report a case of this life-threatening event in a four-year-old boy suffering from a rare genetic disorder, fibrodysplasia ossificans progressiva. He…
Mollie E. Herget, Kristina M. Hufford, Daniel L. Mummey et al. · 2015 · Restoration Ecology
When landscapes are heavily impacted by biological invasion, local populations of native plant species may no longer be adapted to altered environmental conditions. In these cases, it is useful to investigate alternative sources of…
Wil Biddle, David G. Schwark, Margaret A. Schmitt et al. · 2022 · Frontiers in Chemistry
The expansion of the genetic code beyond a single type of noncanonical amino acid (ncAA) is hindered by inefficient machinery for reassigning the meaning of sense codons. A major obstacle to using directed evolution to improve the efficiency of sense codon reassignment is that fractional sense codon reassignments lead to heterogeneous mixtures of full-length proteins with either a ncAA or a natural amino acid incorporated in response to the targeted codon. In stop codon suppression systems, missed incorporations lead to truncated proteins; improvements in activity may be inferred from increase
Janine Stein, Melanie Luppa, Hanna Kaduszkiewicz et al. · 2015 · Psychological Assessment
The aim of the study was to investigate the psychometric properties of a Short Form of the Mini-Mental State Examination (SMMSE) for the screening of dementia in older primary care patients. Data were obtained from a large longitudinal…
Yvonne Stikkelbroek, Gerko Vink, Maaike H. Nauta et al. · 2020 · Scientific Reports
We examined if manualized cognitive behavioral therapy (CBT) was more effective than Treatment As Usual (TAU) for clinically depressed adolescents within routine care. This multisite Randomized controlled trail included 88 clinically depressed adolescents (aged 12-21 years) randomly assigned to CBT or TAU. Multiple assessments (pre-, post treatment and six-month follow-up) were done using semi-structured interviews, questionnaires and ratings and multiple informants. The primary outcome was depressive or dysthymic disorder based on the KSADS. Completers, CBT (n = 19) and TAU (n = 26), showed a
Xiao Hui Gu, Hao Lin, Jun Hong Xia · 2018 · Aquaculture Research
Identifying candidate genes involved into osmoregulation provides a basis for developing molecular markers for breeding of saline tilapia. In this study, we characterized and conducted a functional analysis of the Enhancer of Polycomb…
Arvinder Kaur, Kamaldeep Kaur, Shilpi Jain · 2016
The objective of this paper is to study the relationship between different types of object-oriented software metrics, code smells and actual changes in software code that occur during maintenance period. It is hypothesized that code smells…
Jeong‐Mi Do, Ji Won Hong, Ho‐Sung Yoon · 2025 · Frontiers in Microbiology
Traditional nanoparticle synthesis relies on chemical and physical methods that often involve hazardous reagents, high energy consumption, and environmental toxicity. As a sustainable alternative, biological synthesis utilizes biomolecules in an eco-friendly manner to form nanoparticles. This study explores the green synthesis of silver nanoparticles (AgNPs) using extracellular polymeric substances (EPS) secreted by the microalga Graesiella emersonii KNUA204, highlighting the potential of microalgal biomolecules in nanotechnology. EPS-rich supernatant from G. emersonii enabled AgNP formation u
Ghuzayyil Mohammed Al-Otaibi · 2019 · Journal of language and Education
English as a Foreign Language (EFL) learners find some phrasal verbs problematic because of their idiomatic and polysemous nature. They are frequently used in spoken English and textbooks suggest an arbitrary way in teaching them. Cognitive linguists proposed that the particle plays a major role in determining the meaning of such phrasal verbs. This study investigated the effectiveness of a cognitive approach (i.e., Rudzka-Ostyn’s Model) in teaching taught and new phrasal verbs including metaphorical ones. Using a list of frequent phrasal verbs, a quasi-experimental design was used in which an
Zifei Fay Chen, Weiting Tao · 2020 · International Journal of Strategic Communication
This study investigates whether hybrid strategy would be more effective than corporate social responsibility (CSR) strategy in boosting CSR information recall and company evaluation. Informed by the corporate ability (CA)-CSR-hybrid…
Laura O’Halloran, Brian Pennie, Lee Jollans et al. · 2018 · Alcoholism Clinical and Experimental Research
BACKGROUND: Impulsivity, broadly characterized as the tendency to act prematurely without foresight, is linked to alcohol misuse in college students. However, impulsivity is a multidimensional construct and different subdomains likely…
Nima Jamalian, Marco Gillies, Frédéric Fol Leymarie et al. · 2022
Until recently, Virtual Reality (VR) applications relied on controllers to enable user interaction in virtual environments. With advances in tracking technology, HMDs are now able to track the movements of users’ hands in real-time with…
Travis A. Smith, Eliza M. Mojduszka, Shun Chen · 2020 · Applied Economic Perspectives and Policy
Abstract School meal programs represent the second largest form of food assistance in the United States. Schools receive federal reimbursements, totaling $17 billion in 2018, provided they meet certain nutritional standards. The Healthy…
Robert Riener, Luca Rabezzana, Yves Zimmermann · 2023 · Frontiers in Robotics and AI
The incessant progress of robotic technology and rationalization of human manpower induces high expectations in society, but also resentment and even fear. In this paper, we present a quantitative normalized comparison of performance, to…
Goran Rondovic, Dragan Djordjevic, Ivo Udovicic et al. · 2022 · Biomedicines
Complex immune response to infection has been highlighted, more than ever, during the COVID-19 pandemic. This review explores the immunomodulatory treatment of moderate-to-severe forms of this viral sepsis in the context of specific…
Moran Plonsky-Toder, Daniella Magen, Shirley Pollack · 2023 · Cells
Chronic kidney disease (CKD) constitutes a worldwide epidemic, affecting approximately 10% of the global population, and imposes significant medical, psychological, and financial burdens on society. Individuals with CKD often face elevated…
Mark E. Olver, Sarah M. Beggs Christofferson, Stephen C. P. Wong · 2015 · Behavioral Sciences & the Law
We examined the use of the clinically significant change (CSC) method with the Violence Risk Scale‐Sexual Offender version (VRS‐SO), and its implications for risk communication, in a combined sample of 945 treated sexual offenders from…