Negative / Null Result ReportOpen accessMedicine
Yan Tong, Peter Jezzard, Thomas W. Okell et al. · 2020 · Magnetic Resonance in Medicine
PURPOSE: To improve the labeling efficiency of pseudo-continuous arterial spin labeling (PCASL) at 7T using parallel transmission (pTx). METHODS: maps were acquired in the labeling plane for tagging pulse design. Complex weights of the labeling pulses for each of the 8 transmit channels were calculated to produce a homogenous radiofrequency (RF) -shimmed labeling across the ROIs. Variable-Rate Selective Excitation (VERSE) pulses were also implemented as a part of the labeling pulse train. Whole-brain perfusion-weighted images were acquired under conditions of RF shimming, VERSE with RF shimmin
View details →DOI: 10.1002/mrm.28173Cited by 20 Negative / Null Result Report
Greg Campbell, Andrew Coffey, Heather Miller et al. · 2018 · Animal Production Science
Beef cattle production is the major agricultural pursuit in the arid rangelands of Australia. Dingo predation is often considered a significant threat to production in rangeland beef herds, but there is a need for improved understanding of…
View details →DOI: 10.1071/an17008Cited by 20 Negative / Null Result Report
Paweł Mateusz Nowak, Edyta Sekuła, Paweł Kościelniak · 2020 · Chromatographia
Abstract The choice between capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) is not easy and depends on many factors. An attempt to facilitate this choice is this work, in which both techniques have been…
View details →DOI: 10.1007/s10337-020-03933-9Cited by 20 Negative / Null Result ReportOpen accessMedicine
Pierina Navarria, Federico Pessina, Stefano Tomatis et al. · 2017 · Oncotarget
// Pierina Navarria 1, * , Federico Pessina 2, * , Stefano Tomatis 1 , Riccardo Soffietti 3 , Marco Grimaldi 4 , Egesta Lopci 5 , Arturo Chiti 5, 7 , Antonella Leonetti 9 , Alessandra Casarotti 2 , Marco Rossi 2 , Luca Cozzi 1 , Anna Maria Ascolese 1 , Matteo Simonelli 6, 7 , Simona Marcheselli 8 , Armando Santoro 6, 7 , Elena Clerici 1 , Lorenzo Bello 2 and Marta Scorsetti 1, 7 1 Radiotherapy and Radiosurgery Department, Humanitas Cancer Center and Research Hospital, Rozzano, Italy 2 Neurosurgical Oncology Department, Humanitas Cancer Center and Research Hospital, Rozzano, Italy 3 Consultant
View details →DOI: 10.18632/oncotarget.18809Cited by 20 Negative / Null Result ReportOpen accessMedicine
Muhammad Furqan, Yu-Yu Tien, Mary C. Schroeder et al. · 2018 · Journal of Thoracic Disease
Background: The optimal surgery for resectable pulmonary typical carcinoid (TC), e.g., lobar resection (L-R) vs. sub-lobar resection (SL-R), is controversial. This is further explored in this population-based study. Methods: The…
View details →DOI: 10.21037/jtd.2018.09.141Cited by 20 Negative / Null Result ReportOpen accessMedicine
Malin Assarsson, Jan Söderman, Olaf Dienus et al. · 2020 · Acta Dermato Venereologica
Studies have shown differences in the skin and gut bacterial microbiomes in patients with psoriasis, but the pharyngeal microbiome has not been studied previously. The aim of this study was to investigate differences in the bacterial…
View details →DOI: 10.2340/00015555-3619Cited by 20 Negative / Null Result ReportMedicine
Brian K. Yorkgitis, Danielle Tatum, Sharven Taghavi et al. · 2021 · The Journal of Trauma: Injury, Infection, and Critical Care
BACKGROUND Trauma teams are often faced with patients on antithrombotic (AT) drugs, which is challenging when bleeding occurs. We sought to compare the effects of different AT medications on head injury severity and hypothesized that AT…
View details →DOI: 10.1097/ta.0000000000003421Cited by 20 Negative / Null Result ReportOpen accessMedicine
Juan José Yepes-Núñez, Anita Rajasekhar, Maryam Rahman et al. · 2020 · Blood Advances
The impact of pharmacologic prophylaxis for venous thromboembolism in patients undergoing neurosurgical intervention remains uncertain. We reviewed the efficacy and safety of pharmacologic compared with nonpharmacologic thromboprophylaxis…
View details →DOI: 10.1182/bloodadvances.2020002195Cited by 20 Negative / Null Result ReportOpen accessEnvironmental Science
Lingling Rong, Ligui Wu, Tiao Zhang et al. · 2023 · Molecules
To improve the adsorption efficiency of pollutants by biochar, preparing graphene-like biochar (GBC) or nitrogen-doped biochar are two commonly used methods. However, the difference in the nitrogen doping (N-doping) effects upon the adsorption of pollutants by pristine biochar (PBC) and GBC, as well as the underlying mechanisms, are still unclear. Take the tetracycline (TC) as an example, the present study analyzed the characteristics of the adsorption of TCs on biochars (PBC, GBC, N-PBC, N-GBC), and significant differences in the effects of N-doping on the adsorption of TCs by PBC and GBC wer
View details →DOI: 10.3390/molecules29010173Cited by 20 Negative / Null Result ReportOpen accessMedicine
Oluwamayokun Oshinowo, Renee Copeland, Yumiko Sakurai et al. · 2021 · Blood Advances
Key Points Human, canine, ovine, and porcine platelets exhibit disparate biophysical signatures, whereas human and murine platelets are similar. Multiple biophysical parameters integrate during clot formation, measured by bulk clot…
View details →DOI: 10.1182/bloodadvances.2020003755Cited by 20 Negative / Null Result ReportOpen accessMedicine
Kirsi‐Maija Kaukonen, Suvi T. Vaara, Ville Pettilä et al. · 2013 · Critical Care
INTRODUCTION: Transfusion of red blood cells (RBCs) and, in particular, older RBCs has been associated with increased short-term mortality in critically ill patients. We evaluated the association between age of transfused RBCs and acute kidney injury (AKI), hospital, and 90-day mortality in critically ill patients. METHODS: We conducted a prospective, observational, predefined sub-study within the FINNish Acute Kidney Injury (FINNAKI) study. This study included all elective ICU admissions with expected ICU stay of more than 24 hours and all emergency admissions from September to November 2011.
View details →DOI: 10.1186/cc13045Cited by 20 Negative / Null Result ReportOpen accessMedicine
Santiago Moreno, Bernardino Alcázar-Navarrete, Carlos Dueñas et al. · 2022 · Drug Design Development and Therapy
The aim of this report is to review the literature and shed light on the uncertainties surrounding the use of antiviral agents in general and remdesivir in COVID-19 patients. This review evaluated a battery of antiviral compounds and their…
View details →DOI: 10.2147/dddt.s356951Cited by 20 Negative / Null Result ReportOpen accessMedicine
Jong Hoon Hyun, Moo Hyun Kim, Yujin Sohn et al. · 2021 · BMC Infectious Diseases
Abstract Background Coronavirus disease 2019 (COVID-19) is associated with acute respiratory distress syndrome, and corticosteroids have been considered as possible therapeutic agents for this disease. However, there is limited literature on the appropriate timing of corticosteroid administration to obtain the best possible patient outcomes. Methods This was a retrospective cohort study including patients with severe COVID-19 who received corticosteroid treatment from March 2 to June 30, 2020 in seven tertiary hospitals in South Korea. We analyzed the patient demographics, characteristics, and
View details →DOI: 10.1186/s12879-021-06221-5Cited by 20 Negative / Null Result ReportOpen accessImmunology and Microbiology
Sergio Cleto, Camila Eleutério Rodrigues, Ceila María Sant’Ana Malaque et al. · 2016 · PLoS ONE
BACKGROUND: Leptospirosis is a health problem worldwide. Its most severe form is a classic model of sepsis, provoking acute respiratory distress syndrome (ARDS) and acute kidney injury (AKI), with associated mortality that remains unacceptably high. We previously demonstrated that early initiation of sustained low-efficiency dialysis (SLED) followed by daily SLED significantly decreases mortality. However, the mode of clearance can also affect dialysis patient outcomes. Therefore, the objective of this study was to compare the effects of SLED with traditional (diffusive) clearance, via hemodia
View details →DOI: 10.1371/journal.pone.0160010Cited by 20 Negative / Null Result ReportOpen accessMedicine
Kogieleum Naidoo, Santhanalakshmi Gengiah, Nonhlanhla Yende‐Zuma et al. · 2022 · EClinicalMedicine
Background HIV-TB treatment integration reduces mortality. Operational implementation of integrated services is challenging. This study assessed the impact of quality improvement (QI) for HIV-TB integration on mortality within primary…
View details →DOI: 10.1016/j.eclinm.2022.101298Cited by 20 Negative / Null Result ReportBiochemistry, Genetics and Molecular Biology
April R. Giles, Martin Lock, Shu‐Jen Chen et al. · 2023 · Human Gene Therapy
For successful vector-based gene therapy manufacturing, the selected adeno-associated virus (AAV) vector production system must produce vector at sufficient scale. However, concerns have arisen regarding the quality of vector produced…
View details →DOI: 10.1089/hum.2022.116Cited by 20 Negative / Null Result ReportOpen accessMedicine
Laurent Chiche · 2012 · Therapeutics and Clinical Risk Management
Belimumab is the first biologic approved for patients with systemic lupus erythematosus (SLE). Belimumab is the first of a new class of drug targeting B cell-stimulating factors or their receptors to reach the market. Its target, BLyS,…
View details →DOI: 10.2147/tcrm.s19819Cited by 20 Negative / Null Result ReportOpen accessMedicine
Tanguy Y. Seiwert, Sara Kochanny, Kevin Wood et al. · 2020 · Cancer
BACKGROUND: Patients with cetuximab-resistant, recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) have poor outcomes. This study hypothesized that dual blockade of mammalian target of rapamycin and epidermal growth factor…
View details →DOI: 10.1002/cncr.32929Cited by 20 Negative / Null Result ReportOpen accessMedicine
Anthony Bentley, Samantha Gillard, Michael Spino et al. · 2013 · PharmacoEconomics
BACKGROUND: Patients with β-thalassaemia major experience chronic iron overload due to regular blood transfusions. Chronic iron overload can be treated using iron-chelating therapies such as desferrioxamine (DFO), deferiprone (DFP) and…
View details →DOI: 10.1007/s40273-013-0076-zCited by 20 Negative / Null Result Report
Rezzy Eko Caraka, Yusra Yusra, Toni Toharudin et al. · 2021 · Sustainability
Background and objectives: The impacts of COVID-19 are like two sides of one coin. During 2020, there were many research papers that proved our environmental and climate conditions were improving due to lockdown or large-scale restriction…
View details →DOI: 10.3390/su13115946Cited by 20 Negative / Null Result Report
Yukari Kobayashi, Jennifer A. Tremmel, Yuhei Kobayashi et al. · 2015 · Journal of the American Heart Association
Background Although a myocardial bridge ( MB ) is often regarded as a benign coronary variant, recent studies have associated MB with focal myocardial ischemia. The physiological consequences of MB on ventricular function during stress…
View details →DOI: 10.1161/jaha.115.002496Cited by 20 Negative / Null Result Report
Remco van Dijk, Sem J. Aronson, Dirk R. de Waart et al. · 2017 · Scientific Reports
Abstract We aimed to identify potent biliverdin reductase (BVRA) inhibitors as a novel concept for the treatment of severe unconjugated hyperbilirubinemia. 1280 FDA-approved compounds were screened in vitro for their ability to inhibit…
View details →DOI: 10.1038/s41598-017-01602-wCited by 20 Negative / Null Result Report
W. Roether, J. E. Lupton · 2011 · Ocean Science
Abstract. Observations of tritium and 3He in the Tyrrhenian Sea, 1987–2009, confirm the enhanced vertical mixing of intermediate waters into the deep waters that has been noted and associated with the Eastern Mediterranean Transient in…
View details →DOI: 10.5194/os-7-91-2011Cited by 20 Negative / Null Result Report
Nadia A. Abdelmegeed Abdelwahed, Bahadur Ali Soomro, Naimatullah Shah · 2022 · Management of Environmental Quality: An International Journal
Purpose The study investigates the intention to adopt climate change and the pro-environmental behaviours among the residents of a developing country (Pakistan) through the theory of planned behaviour (TPB). Design/methodology/approach…
View details →DOI: 10.1108/meq-10-2021-0236Cited by 20 Negative / Null Result ReportOpen accessMedicine
Lily R. Aleksandrova, Yu Tian Wang, Anthony G. Phillips · 2017 · Chronic Stress
The prevailing hypothesis of ketamine's unique antidepressant effects implicates N-methyl-d-aspartate receptor (NMDAR) inhibition-dependent enhancement of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated transmission,…
View details →DOI: 10.1177/2470547017743511Cited by 20 Negative / Null Result ReportOpen accessMedicine
Arran T. Reader, Victoria S. Trifonova, H. Henrik Ehrsson · 2021 · European Journal of Neuroscience
Body ownership refers to the distinct sensation that our observed body belongs to us, which is believed to stem from multisensory integration. This is commonly shown through the rubber hand illusion (RHI), which induces a sense of ownership over a false limb. Whilst the RHI may interfere with object-directed action and alter motor cortical activity, it is not yet clear whether a sense of ownership over an artificial hand has functional consequences for movement production per se. As such, we performed two motion-tracking experiments (n = 117) to examine the effects of the RHI on the reaction t
View details →DOI: 10.1111/ejn.15444Cited by 20 Negative / Null Result ReportOpen accessMedicine
Thi Yen Loan Le, Hilda A. Pickett, Andrian Yang et al. · 2019 · Scientific Reports
We have previously reported a subpopulation of mesenchymal stromal cells (MSCs) within the platelet-derived growth factor receptor-alpha (PDGFRα)/CD90 co-expressing cardiac interstitial and adventitial cell fraction. Here we further characterise PDGFRα/CD90-expressing cardiac MSCs (PDGFRα + cMSCs) and use human telomerase reverse transcriptase (hTERT) over-expression to increase cMSCs ability to repair the heart after induced myocardial infarction. hTERT over-expression in PDGFRα + cardiac MSCs (hTERT + PDGFRα + cMSCs) modulates cell differentiation, proliferation, survival and angiogenesis re
View details →DOI: 10.1038/s41598-019-47022-wCited by 20 Negative / Null Result ReportOpen accessNeuroscience
Megan Willis, Andrea I. Costantino, Michael A. Nitsche et al. · 2019 · Frontiers in Neuroscience
There has been increasing interest in the utility of transcranial electrical stimulation as a tool to enhance cognitive abilities. In the domain of face perception, enhancements have been reported for both transcranial direct current stimulation (tDCS) and high-frequency transcranial random noise stimulation (tRNS) targeting the occipitotemporal cortex. In a series of two experiments, we attempted to replicate these findings for face identity perception, and extend on previous studies, to determine if similar enhancements are also observed for object and facial expression perception. In Experi
View details →DOI: 10.3389/fnins.2019.00078Cited by 20 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Santiago López‐Miranda, Daniel Berdejo, Elisa Pagán et al. · 2020 · Journal of the Science of Food and Agriculture
Abstract BACKGROUND The antimicrobial activity of essential oils and their constituents has led to increasing interest in using them as natural preservative agents. However, their high sensitivity to light and oxygen, their volatility and…
View details →DOI: 10.1002/jsfa.11017Cited by 20 Negative / Null Result ReportOpen accessSocial Sciences
Cristian Vasco · 2013 · Americanae (AECID Library)
Con datos de la “Encuesta de condiciones de vida (ecv) 2005-2006”, este artículo analiza el impacto de la migración internacional y las remesas en la iniciativa emprendedora en el Ecuador rural. Los resultados sugieren que ni la migración…
View details →DOI: 10.17428/rmi.v7i1.685Cited by 20 