Negative / Null Result Report2019
GLP 1 Regulated Intestinal Cell’s Insulin Expression and Selfadaptation before the Onset of Type 2 Diabetes
Advanced Pharmaceutical Bulletin
Failure-mode index
Negative results in Therapeutics. Pharmacology
35 indexed negative results, null findings, and replication failures in Therapeutics. Pharmacology. Each entry is a real published study whose primary finding was negative — learn what already failed before you repeat it.
Most-cited failures in Therapeutics. Pharmacology
Negative / Null Result Report2008
Changes in Essential Oil Content and Yield of Basil in Response to Different Levels of Nitrogen and Plant Density
Journal of Medicinal Plants
Negative / Null Result Report2022
18β-Glycyrrhetinic Acid Induces Metabolic Changes and Reduces Staphylococcus aureus Bacterial Cell-to-Cell Interactions
Antibiotics
Negative / Null Result Report2020
Interaction analysis of glycoengineered antibodies with CD16a: a native mass spectrometry approach
mAbs
Negative / Null Result Report2025
Drug Interaction Potential of Berberine Hydrochloride When Co-Administered with Tofacitinib and Filgotinib in Rats
Drug Design, Development and Therapy
Negative / Null Result Report2024
Impaired Upper Airway Muscle Function with Excessive or Deficient Dietary Intake of Selenium in Rats
Antioxidants
Negative / Null Result Report2026
Effect of End-Stage Kidney Disease Factor on the Sedative Effects of Ciprofol
Drug Design, Development and Therapy
Negative / Null Result Report2022
Study and exploration of the pharmacokinetics of traditional Tibetan medicine Ruyi Zhenbao tablets after single and long-term administration
Frontiers in Pharmacology
Negative / Null Result Report2023
The effect of adding ivermectin to the standard COVID-19 treatment in intubated patients
Journal of Nephropharmacology
Negative / Null Result Report2022
Herb Formula (GCis) Prevents Pulmonary Infection Secondary to Intracerebral Hemorrhage by Enhancing Peripheral Immunity and Intestinal Mucosal Immune Barrier
Frontiers in Pharmacology
Negative / Null Result Report2024
Impact of a DSS-supported medication review on the safety of drug therapy and quality of life in patients with antithrombotic therapy
Frontiers in Pharmacology
Negative / Null Result Report2026
Safety of using the intravenous beta-1-adrenoblocker esmolol in patients with ST-segment elevation myocardial infarction before primary percutaneous coronary intervention
Рациональная фармакотерапия в кардиологии
Negative / Null Result Report2022
Comparison between conventional and micro-assisted periodontal surgery: Case series
Journal of Advanced Pharmaceutical Technology & Research
Negative / Null Result Report2017
Synchronic Effect of Curcumin and swimming training on depression in morphine addicted male mice
Journal of Medicinal Plants
Negative / Null Result Report2018
Organic mononitrites of 1,2-propanediol act as an effective NO-releasing vasodilator in pulmonary hypertension and exhibit no cross-tolerance with nitroglycerin in anesthetized pigs
Drug Design, Development and Therapy
Negative / Null Result Report2023
Effect of evolocumab on the progression of intraplaque neovascularization of the carotid based on contrast-enhanced ultrasonography (EPIC study): A prospective single-arm, open-label study
Frontiers in Pharmacology
Negative / Null Result Report2013
Evaluation of Hand Stereognosis Level in 3-6 years Old Children with Spastic Hemiplegia and Diplegia
Journal of Rehabilitation
Negative / Null Result Report2017
Effectiveness and safety of topical tacrolimus in treatment of vitiligo
Journal of Advanced Pharmaceutical Technology & Research
Negative / Null Result Report2020
Hydroxychloroquine as a Chemoprophylactic Agent for COVID-19: A Clinico-Pharmacological Review
Frontiers in Pharmacology
Negative / Null Result Report2025
A Pilot Study on the Impact of Cranberry and Ascorbic Acid Supplementation on the Urinary Microbiome of Healthy Women: A Randomized Controlled Trial
Antibiotics
Negative / Null Result Report2022
Comparison of efficacy and safety of vildagliptin 50 mg tablet twice daily and vildagliptin 100 mg sustained release once daily tablet on top of metformin in Indian patients with Type 2 diabetes mellitus: A randomized, open label, Phase IV parallel group, clinical trial
National Journal of Physiology, Pharmacy and Pharmacology
Negative / Null Result Report2023
Mitochondrial ROS Accumulation Contributes to Maternal Hypertension and Impaired Remodeling of Spiral Artery but Not IUGR in a Rat PE Model Caused by Maternal Glucocorticoid Exposure
Antioxidants
Negative / Null Result Report2025
Ineffective behavioral rescue despite partial brain Dp427 restoration by AAV9-U7-mediated exon 51 skipping in mdx52 mice
Molecular Therapy: Nucleic Acids
Negative / Null Result Report2025
Early cognitive decline in amyotrophic lateral sclerosis and its relation to driving: an observational study
Journal of Rehabilitation Medicine
Negative / Null Result Report2022
TSH-β gene polymorphism in Saudi patients with thyroid cancer: A case-control study
Saudi Pharmaceutical Journal
Negative / Null Result Report2020
Does the frequency domain parameters among pregnant women with gestational hypertension associated with levels of serum zinc, magnesium, and copper? A cross-sectional study
National Journal of Physiology, Pharmacy and Pharmacology
Negative / Null Result Report2022
The Association Between Proton Pump Inhibitors and COVID-19 is Confounded by Hyperglycemia in a Population-Based Study
Frontiers in Pharmacology
Negative / Null Result Report2017
Zolpidem Administration and Risk of Hepatocellular Carcinoma: A Case-Control Study in Taiwan
Frontiers in Pharmacology
Negative / Null Result Report2017
The association of vitamin D deficiency and glucose control among diabetic patients
Saudi Pharmaceutical Journal
Negative / Null Result Report2025
Population Pharmacokinetics and Exposure–Response Analysis of Serplulimab in Small Cell Lung Cancer Patients
Clinical and Translational Science
Negative / Null Result Report2026
Correlation Between Hip Abductor Strength and Lower Extremity Functional Scale in Elderly Females
Physical Therapy Korea
Failed Experiment Report2018
Effect of Linagliptin and Voglibose on metabolic profile in patients with Type 2 Diabetes: a randomized, double-blind, placebo-controlled trial
BMC Pharmacology and Toxicology
Negative / Null Result Report2019
The influence of telmisartan on metformin pharmacokinetics and pharmacodynamics
Journal of Pharmacological Sciences
Negative / Null Result Report2023
Stress perception among the elderly and its effect on some muscle strength parameters
National Journal of Physiology, Pharmacy and Pharmacology
Negative / Null Result Report2023
Evaluation of Bile Salts on the Survival and Modulation of Virulence of Aliarcobacter butzleri
Antibiotics