Hydroxychloroquine as a Chemoprophylactic Agent for COVID-19: A Clinico-Pharmacological Review
Mudit Agarwal; Piyush Ranjan; Upendra Baitha; Ankit Mittal · 2020 · Frontiers in Pharmacology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Hydroxychloroquine has gained much attention as one of the candidate drugs that can be repurposed as a prophylactic agent against SARS-CoV-2, the agent responsible for the COVID-19 pandemic. Due to high transmissibility and presence of asymptomatic carriers and presymptomatic transmission, there is need for a chemoprophylactic agent to protect the high-risk population. In this review, we dissect the currently available evidence on hydroxychloroquine prophylaxis from a clinical and pharmacological point of view. In vitro studies on Vero cells show that hydroxychloroquine effectively inhibits SA
Abstract by Mudit Agarwal; Piyush Ranjan; Upendra Baitha; Ankit Mittal, Frontiers in Pharmacology (2020) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.3389/fphar.2020.593099