Impaired Upper Airway Muscle Function with Excessive or Deficient Dietary Intake of Selenium in Rats
David P. Burns; Sarah E. Drummond; Stefanie Wölfel; Kevin H. Murphy; Joanna Szpunar; Ken D. O’Halloran; John J. Mackrill · 2024 · Antioxidants
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Obstructive sleep apnoea (OSA) involves impaired upper airway muscle function and is linked to several pathologies including systemic hypertension, daytime somnolence and cognitive decline. Selenium is an essential micronutrient that exerts many of its effects through selenoproteins. Evidence indicates that either deficient or excessive dietary selenium intake can result in impaired muscle function, termed nutritional myopathy. To investigate the effects of selenium on an upper airway muscle, the sternohyoid, rats were fed on diets containing deficient, normal (0.5 ppm sodium selenite) or exce
Abstract by David P. Burns; Sarah E. Drummond; Stefanie Wölfel; Kevin H. Murphy; Joanna Szpunar; Ken D. O’Halloran; John J. Mackrill, Antioxidants (2024) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.3390/antiox13091080