Study and exploration of the pharmacokinetics of traditional Tibetan medicine Ruyi Zhenbao tablets after single and long-term administration
Hongping Hou; Tengfei Chen; Ziying Xu; Zihui Yu; Caixia Wang; Rongxia Liu; Bo Peng; Wei Yang · 2022 · Frontiers in Pharmacology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Tibetan medicine is one of the oldest traditional medicine systems in the world. Taking the Ruyi Zhenbao tablet (RYZB) as an example, which is a widely used classic oral Tibetan medicine, this article discusses the pharmacokinetics of single administration and long-term treatment and analyzed its metabolic properties and tissue distribution in vivo. After single administration, blood samples were collected before administration and at different time points after administration in different groups of rats. In the study of long-term treatment effects, blood samples were collected from the animal
Abstract by Hongping Hou; Tengfei Chen; Ziying Xu; Zihui Yu; Caixia Wang; Rongxia Liu; Bo Peng; Wei Yang, Frontiers in Pharmacology (2022) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
Changes in Essential Oil Content and Yield of Basil in Response to Different Levels of Nitrogen and Plant Density
Negative / Null Result Report18β-Glycyrrhetinic Acid Induces Metabolic Changes and Reduces Staphylococcus aureus Bacterial Cell-to-Cell Interactions
Negative / Null Result ReportInteraction analysis of glycoengineered antibodies with CD16a: a native mass spectrometry approach
Negative / Null Result ReportDrug Interaction Potential of Berberine Hydrochloride When Co-Administered with Tofacitinib and Filgotinib in Rats
Negative / Null Result ReportImpaired Upper Airway Muscle Function with Excessive or Deficient Dietary Intake of Selenium in Rats
Negative / Null Result ReportGLP 1 Regulated Intestinal Cell’s Insulin Expression and Selfadaptation before the Onset of Type 2 Diabetes
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: DOAJ · DOI 10.3389/fphar.2022.948693
