Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Kirandeep Bhullar, Maryam Zarepour, Hongbing Yu et al. · 2015 · Infection and Immunity
Bacterial pathogens produce a number of autotransporters that possess diverse functions. These include the family of serine protease autotransporters of Enterobacteriaceae (SPATEs) produced by enteric pathogens such as Shigella flexneri…
View details →DOI: 10.1128/iai.00025-15Cited by 29 Negative / Null Result Report
Christopher W. Noel, Caitlin McMullen, Christopher Yao et al. · 2018 · The Laryngoscope
Objectives The Fragility Index (FI) is a novel tool for evaluating the robustness of statistically significant findings in a randomized control trial (RCT). It measures the number of events upon which statistical significance depends. We…
View details →DOI: 10.1002/lary.27183Cited by 29 Negative / Null Result ReportOpen accessNeuroscience
John D. Tompkins, Todd A. Clason, Jean C. Hardwick et al. · 2016 · American Journal of Physiology-Cell Physiology
Pituitary adenylate cyclase (PAC)-activating polypeptide (PACAP) peptides ( Adcyap1) signaling at the selective PAC1 receptor ( Adcyap1r1) participate in multiple homeostatic and stress-related responses, yet the cellular mechanisms…
View details →DOI: 10.1152/ajpcell.00164.2016Cited by 29 Negative / Null Result ReportOpen accessPhysics and Astronomy
Sukanta Deb, Harinder P. Singh, Subhash Kumar et al. · 2015 · Monthly Notices of the Royal Astronomical Society
We present a study of three-dimensional structure of the Small Magellanic Cloud (SMC). The V- and I-band light curves of the fundamental mode RR Lyrae (RRab) stars obtained by the Optical Gravitational Lensing Experiment-III project were…
View details →DOI: 10.1093/mnras/stv358Cited by 29 Negative / Null Result ReportOpen accessMaterials Science
Qi Li, Rongchao Jin · 2017 · Nanotechnology Reviews
Abstract Silicon nanoparticles (NPs) have long been regarded as a promising alternative for commercial organic dyes and typical quantum dots (e.g. CdSe) for applications in light emitting, bio-imaging, sensing, etc. The photoluminescence…
View details →DOI: 10.1515/ntrev-2017-0145Cited by 29 Negative / Null Result ReportOpen accessSocial Sciences
Michael N. Stagnaro, Ben M Tappin, David G. Rand · 2023 · Proceedings of the National Academy of Sciences
The highly influential theory of "Motivated System 2 Reasoning" argues that analytical, deliberative ("System 2") reasoning is hijacked by identity when considering ideologically charged issues-leading people who are more likely to engage in such reasoning to be more polarized, rather than more accurate. Here, we fail to replicate the key empirical support for this theory across five contentious issues, using a large gold-standard nationally representative probability sample of Americans. While participants were more accurate in evaluating a contingency table when the outcome aligned with thei
View details →DOI: 10.1073/pnas.2301491120Cited by 29 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Yuan Gao, Dokyun Lee, Gordon Burtch et al. · 2025 · Proceedings of the National Academy of Sciences
Recent studies suggest large language models (LLMs) can generate human-like responses, aligning with human behavior in economic experiments, surveys, and political discourse. This has led many to propose that LLMs can be used as surrogates…
View details →DOI: 10.1073/pnas.2501660122Cited by 29 Negative / Null Result ReportOpen accessPsychology
Jonathan Jarrett, Tyler R. Bonnell, Christopher Young et al. · 2018 · Proceedings of the Royal Society B Biological Sciences
, 12084 (doi:10.1038/ncomms12084)) has demonstrated that network structure can be maintained by a simple process of social inheritance. Here, we ask how juvenile vervet monkeys integrate into their adult grooming networks, using the model…
View details →DOI: 10.1098/rspb.2017.2668Cited by 29 Negative / Null Result ReportOpen accessMedicine
Sara Lindström, Fredrick R. Schumacher, Daniele Campa et al. · 2012 · Cancer Epidemiology Biomarkers & Prevention
BACKGROUND: A recent genome-wide association study (GWAS) of prostate cancer in a Japanese population identified five novel regions not previously discovered in other ethnicities. In this study, we attempt to replicate these five loci in a…
View details →DOI: 10.1158/1055-9965.epi-11-0870-tCited by 29 Negative / Null Result ReportOpen accessMedicine
Linda Zaharenko, Ineta Kalniņa, Kristine Geldnere et al. · 2016 · European Journal of Endocrinology
Objective(s) High variability in clinical response to metformin is often observed in type 2 diabetes (T2D) patients, and it highlights the need for identification of genetic components affecting the efficiency of metformin therapy. Aim of…
View details →DOI: 10.1530/eje-16-0347Cited by 29 Negative / Null Result ReportOpen accessMedicine
Cerissa L. Blaney, Mark L. Robbins, Andrea L. Paiva et al. · 2012 · American Journal of Health Promotion
PURPOSE: African-Americans have high rates of physical inactivity-related morbidity and mortality, thus effective interventions to increase exercise are necessary. Tailored interventions show promise, but measures need validation in this…
View details →DOI: 10.4278/ajhp.091214-quan-393Cited by 29 Negative / Null Result ReportNeuroscience
Harrison E. Vieth, Katie L. McMahon, Greig I. de Zubicaray · 2014 · Quarterly Journal of Experimental Psychology
How does the presence of a categorically related word influence picture naming latencies? In order to test competitive and noncompetitive accounts of lexical selection in spoken word production, we employed the picture-word interference…
View details →DOI: 10.1080/17470218.2014.923922Cited by 29 Negative / Null Result Report
Otto A. Sanchez, Elizabeth A. Copenhaver, Christopher P. Elder et al. · 2010 · Magnetic Resonance in Medicine
Abstract Blood oxygenation level dependent (BOLD) contrast in skeletal may reflect the contributions of both intravascular and extravascular relaxation effects. The purpose of this study was to determine the significance of the…
View details →DOI: 10.1002/mrm.22449Cited by 29 Negative / Null Result Report
Arjen Alink, Hunar Abdulrahman, Richard N. Henson · 2018 · Nature Communications
Abstract Inferring neural mechanisms from functional magnetic resonance imaging (fMRI) is challenging because the fMRI signal integrates over millions of neurons. One approach is to compare computational models that map neural activity to…
View details →DOI: 10.1038/s41467-018-05957-0Cited by 29 Negative / Null Result ReportMedicine
Hsi‐Chin Wu, Chao‐Hsiang Chang, Ru-Yin Tsai et al. · 2010 · PubMed
Prostate cancer is the most common cause of cancer death in men and is a major health problem worldwide. Methylene tetrahydrofolate reductase (MTHFR) plays an important role in folate metabolism and is also an important source of DNA…
Negative / Null Result ReportOpen accessPsychology
Chun-Yu Kuo, Yang-Ming Huang, Yei‐Yu Yeh · 2018 · Frontiers in Psychology
Cognitive training and social engagement are two of the routes that potentially improve cognitive functions in older adults. The former targets specific functions so that an intervention can trigger the plasticity and efficiency of the underpinning neural systems, and the latter also provides an environment supportive of social and emotional needs. We investigated whether an integration of the two routes could enhance cognitive functions related to executive control, because no prior research has adopted a theory-driven approach to design a group-based cognitive training program for executive
View details →DOI: 10.3389/fpsyg.2018.02482Cited by 29 Negative / Null Result Report
Ullrich K. H. Ecker, Caitlin X. M. Sharkey, Briony Swire-Thompson · 2023 · PLOS ONE
Individuals often continue to rely on misinformation in their reasoning and decision making even after it has been corrected. This is known as the continued influence effect, and one of its presumed drivers is misinformation familiarity.…
View details →DOI: 10.1371/journal.pone.0281140Cited by 29 Negative / Null Result ReportOpen accessMedicine
Thibaut Vaulet, M. Al‐Memar, H. Fourie et al. · 2021 · Computer Methods and Programs in Biomedicine
BACKGROUND: Clinical models to predict first trimester viability are traditionally based on multivariable logistic regression (LR) which is not directly interpretable for non-statistical experts like physicians. Furthermore, LR requires…
View details →DOI: 10.1016/j.cmpb.2021.106520Cited by 29 Negative / Null Result ReportOpen accessMedicine
Matthew J. Fisher, Luis A Marcos Raymundo, Melinda Monteforte et al. · 2020 · International Journal of Infectious Diseases
OBJECTIVES: The purpose of this study is to evaluate clinical outcomes in patients with critical COVID-19 pneumonia requiring invasive mechanical ventilation who were treated with tocilizumab DESIGN: Single-center retrospective cohort…
View details →DOI: 10.1016/j.ijid.2020.12.021Cited by 29 Negative / Null Result ReportOpen accessEnergy
Xiaoyu Chen, Dongli Wei, Mårten S. G. Ahlquist · 2021 · Organometallics
A CoPc/CNT system has been only recently reported to transform CO2 to methanol via electrochemical reductions, despite the fact that catalyst has been studied extensively since the 1980s. The explanation of high methanol selectivity lies behind the fact that in the new report CoPc exists mainly as a monomer, while in earlier works aggregates dominate. Here, we have studied the reactivity of monomeric and dimeric CoPc by DFT. The mechanism involves rate-limiting CO2 association, with the C–O cleavage step having very similar activation free energy. Once the Co–CO– intermediate is formed, the re
View details →DOI: 10.1021/acs.organomet.1c00431Cited by 29 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Francesco Giuseppe De Rosa, Silvia Corcione, Giovanni Di Perri et al. · 2015 · PubMed
Tigecycline, the first member of the glycylcyclines, has been approved for complicated skin and soft tissue infections (cSSTIs) and complicated intra-abdominal infections (cIAIs). It has a wide range of activity against Gram-positive and…
Negative / Null Result ReportOpen accessMedicine
Michael Weller, Michael Lim, Ahmed Idbaïh et al. · 2021 · Neuro-Oncology
Abstract BACKGROUND Novel therapies are needed in newly diagnosed glioblastoma as nearly all patients experience recurrence following standard-of-care radiotherapy (RT) + temozolomide (TMZ), including patients with tumors with methylated…
View details →DOI: 10.1093/neuonc/noab196.217Cited by 29 Negative / Null Result ReportOpen accessMedicine
Liangzhi Zhong, Lu Chen, Shengqing Lv et al. · 2019 · Radiation Oncology
PURPOSE: Despite recent advances in multimodal treatments, the prognosis of patients with glioblastoma multiforme (GBM) remains poor. The aim of this study was to evaluate the efficacy of moderately hypofractionated simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) combined with temozolomide (TMZ) for the postoperative treatment of GBM. MATERIALS AND METHODS: From February 2012 to February 2018, 80 patients with newly diagnosed and histologically confirmed GBM in our institute were reviewed retrospectively. All patients underwent complete resection or partial resection
View details →DOI: 10.1186/s13014-019-1305-1Cited by 29 Negative / Null Result ReportOpen accessMedicine
C. Gianna Hoffman-Luca, Chao-Yie Yang, Jianfeng Lü et al. · 2015 · PLoS ONE
SAR405838 is a potent and specific MDM2 inhibitor currently being evaluated in Phase I clinical trials for the treatment of human cancer. Using the SJSA-1 osteosarcoma cell line which harbors an amplified MDM2 gene and wild-type p53, we have investigated the acquired resistance mechanisms both in vitro and in vivo to SAR405838. Treatment of SJSA-1 cells with SAR405838 in vitro leads to dose-dependent cell growth inhibition, cell cycle arrest and robust apoptosis. However, prolonged treatment of SJSA-1 cells in vitro with SAR405838 results in profound acquired resistance to the drug. Analysis o
View details →DOI: 10.1371/journal.pone.0128807Cited by 29 Negative / Null Result ReportOpen accessMedicine
Mingqiu Chen, Minmin Shen, Yu Lin et al. · 2018 · Radiation Oncology
BACKGROUND: The aim of the present study was to assess the efficacy of adjuvant chemotherapy (AC) in patients with esophageal squamous cell carcinoma (ESCC) treated with definitive chemoradiotherapy (CRT). METHODS: The clinical data of patients with ESCC treated with chemoradiotherapy with or without AC were collected and retrospectively reviewed. The overall survival (OS), locoregional failure-free survival (LFFS) and distant failure-free survival (DFFS) rates were analyzed statistically. RESULTS: A total of 187 patients fulfilled the inclusion criteria, 98 of whom were treated with CRT-alone
View details →DOI: 10.1186/s13014-018-1086-yCited by 29 Negative / Null Result ReportMedicine
Alisa M. Higgins, Sandra Peake, Rinaldo Bellomo et al. · 2019 · Critical Care Medicine
OBJECTIVES: To examine long-term survival and quality of life of patients with early septic shock. DESIGN: Prospective, randomized, parallel-group trial. SETTING: Fifty-one hospitals in Australia, New Zealand, Finland, Hong Kong, and the…
View details →DOI: 10.1097/ccm.0000000000003762Cited by 29 Negative / Null Result ReportMedicine
Vivian E. Strong, Sam S. Yoon · 2013 · World Journal of Surgery
Much debate still exists regarding the appropriate extent of lymphadenectomy for gastric adenocarcinoma. In high incidence countries in Eastern Asia, more extensive (e.g. D2) lymphadenectomies are standard, and these surgeries are…
View details →DOI: 10.1007/s00268-013-2070-1Cited by 29 Negative / Null Result ReportMedicine
Amy Thomas, Khaled Dajani, John P. Neoptolemos et al. · 2010 · Digestive Diseases
Pancreatic cancer is one of the major causes of cancer death in Europe with a 5-year survival rate of less than 5%. Although surgery cannot guarantee a cure, the 5-year survival does improve to around 10% following resection and increases…
View details →DOI: 10.1159/000320099Cited by 29 Negative / Null Result ReportMedicine
Shiow‐Ching Shun, Kun‐Huei Yeh, Jin‐Tung Liang et al. · 2013 · Oncology nursing forum
PURPOSE/OBJECTIVES: To explore the association between supportive care needs and type D personality, and to identify personality traits, including negative affectivity (NA) and social inhibition (SI), and their influence on the supportive…
View details →DOI: 10.1188/14.onf.e3-e11Cited by 29 Negative / Null Result ReportOpen accessEngineering
S. M. Abd Elazim, M.H. Elkholy, Abdelrahman Elgarhy et al. · 2025 · Scientific Reports
Growing integration of renewable energy sources (RESs) into power grids has several advantages, including reduced greenhouse gas emissions and improved energy sustainability. Despite the related benefits, RES integration also poses actual…
View details →DOI: 10.1038/s41598-025-14143-4Cited by 29 