A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
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Goicochea-Rios E, Otiniano NM · 2026 · Preprint
Background: To evaluate the effectiveness of an educational intervention in the integral care of patients with diabetes mellitus. Methods A pre-experimental study was carried out with 103 patients with diabetes mellitus treated at Essalud,…
Ghiri AA, Cavanaugh SJ, Nuñez AA et al. · 2026 · Annals of biomedical engineering
While American football games are played across a wide range of temperatures, current helmet rating protocols assess performance primarily at room temperature. This study evaluates how temperature influences impact attenuation performance…
Hyun HK, Lee OH, Roh JW et al. · 2026 · Yonsei medical journal
Purpose Patients with acute coronary syndrome (ACS) on ticagrelor-based dual antiplatelet therapy (DAPT) have an increased risk of gastrointestinal (GI) bleeding. However, evidence supporting the protective role of proton pump inhibitors…
Li X, Liu C, Wu W et al. · 2026 · Frontiers in neuroscience
Purpose To investigate the short-term effect of a longpass filter on myopic defocus-induced changes in axial length (AL) and choroidal thickness (ChT). Methods This study included 23 young myopic adults. AL and ChT were measured in both…
Shetty PMV, Matzen A, Hille S et al. · 2026 · Scientific reports
Marfan syndrome (MFS) is a connective tissue disorder caused by FBN1 mutations, characterised by aortic aneurysms leading to life-threatening dissections. Asprosin is the C-terminal propeptide of fibrillin-1 that was shown to function as a…
Lou Z, Yang H · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
OBJECTIVE: The objective of this study was to evaluate the graft success rate, hearing outcomes, and complications associated with three-layer graft myringoplasty for repairing subtotal and total perforations. MATERIALS AND METHODS:…
Phillipson J, Menson E, Barclay S et al. · 2026 · Archives of disease in childhood
Objective Evaluation of the Medical Mediation Foundation's Conflict Management Programme (CMP)-a structured process for managing conflict. Design Mixed-methods evaluation using Kirkpatrick's framework, a four-level model for evaluating…
Xiang Y, Li S, Wang T et al. · 2026 · Seizure
Background This study aimed to evaluate the effectiveness of the China Acute Seizure Action Plan (CASAP), a context-adapted acute seizure action plan developed for China, on caregivers' knowledge, attitudes, and practices (KAP) regarding…
Greene T, Dicker-Oren SD, Sznitman SR et al. · 2026 · Journal of traumatic stress
The processing of positive memories technique (PPMT) is a promising new treatment for posttraumatic stress disorder (PTSD) involving the detailed narration and processing of specific positive autobiographical memories. This study used an…
Scott R, Sale C, James R et al. · 2026 · Bone
Exercise interventions frequently prescribe impact activities assuming that identical tasks produce similar mechanical loads, yet few studies quantify the external loads experienced during such interventions. This study examined drop-jump…
Sadic AK, Susgun S, Alkhalidi D et al. · 2026 · Nutrition and health
BackgroundAspartame, a widely used artificial sweetener, is metabolized into phenylalanine, aspartic acid, and methanol. Previous studies have suggested that these metabolites may exert detrimental effects on the human body, particularly…
Huang CT, Wen YT, Liu PK et al. · 2026 · QJM : monthly journal of the Association of Physicians
Background Indirect traumatic optic neuropathy (TON) is associated with severe vision loss and no proven treatment. Aim To evaluate the safety and exploratory functional outcomes of intravitreal pegfilgrastim in patients with indirect TON.…
Hodgson NA, Latif S, Talwar S et al. · 2026 · Journal of the American Geriatrics Society
Background The Alzheimer's Association partnered with health systems in Illinois, Greater Missouri, and Washington to implement and evaluate the Knight Family dementia care coordination (DCC) program, a novel telephone-based care…
Deniz B, Arpaci MF, Pekmez H et al. · 2026 · Journal of neuro-oncology
Purpose Brain tumors, characterized by the uncontrolled proliferation of abnormal cells within cerebral tissue, remain clinically challenging entities. Radiotherapy and chemotherapy constitute fundamental therapeutic modalities; however,…
Virupakshaiah A, Gill AJ, Schoeps VA et al. · 2026 · Brain and behavior
Purpose/introduction The anti-JC virus (JCV) antibody index is used to stratify the risk of progressive multifocal leukoencephalopathy (PML) in multiple sclerosis (MS), particularly with natalizumab therapy. B-cell-depleting therapies may…
Sen E, Aytekin A · 2026 · Revista da Associacao Medica Brasileira (1992)
Objective Thiol-disulfide homeostasis is a marker of oxidative stress. The aim of the study was to compare the effects of low-flow desflurane and sevoflurane anesthesia on perioperative changes in thiol-disulfide balance in patients…
Sinha R, Singh R, Tripathi M et al. · 2025 · Indian journal of ophthalmology
Purpose To study the change in the vault of phakic Intraocular Lens (IOL) (pIOL) with RT view anterior segment optical coherence tomography (ASOCT) in different light conditions and define its relationship with the change in pupillary…
Hu G, Xie M, Wang G et al. · 2026 · Preprint
Abstract Background and aim Soil microbiomes are critical for sustaining ecosystem functioning and soil health. Monocropping often disrupts soil microbial communities, leading to yield penalties and soil degradation. Although bio-organic…
Bachelard L, Blanc N, Michel A · 2026 · BMJ supportive & palliative care
Objective Breast cancer surgery often leads to a high burden of distressing symptoms, underscoring the need for supportive care to help patients throughout the perioperative period. This pilot study aimed to evaluate the feasibility,…
Mosch B, Diers M · 2026 · Pain reports
Introduction Since the outbreak of COVID-19, many studies have investigated long-term consequences associated to the pandemic. Undoubtedly, restrictions and changes in everyday life during that time have had a broad impact on mental health…
Achar A, Houser P, Cherian J et al. · 2026 · Lupus
ObjectiveTo determine the long-term outcomes of patients with moderate-severe pediatric systemic lupus erythematosus (pSLE) treated with systematic administration of combination rituximab (RTX) and cyclophosphamide (CYC) at our…
Burger C, Pirotte M, Ray K et al. · 2026 · The western journal of emergency medicine
Introduction Emergency physicians commonly receive feedback in the form of performance metrics such as patients seen per hour. Reviewing metrics has been associated with increased stress and burnout. Although effects on efficiency have…
Arunga S, Ebong A, Orishaba F et al. · 2026 · Preprint
Purpose To provide the latest update on the epidemiology of microbial keratitis in Uganda. Methods We prospectively recruited patients presenting with microbial keratitis (MK) at three eye units in Uganda between November 2023 and June…
Jang YE, Kim Y, Kim HI et al. · 2026 · Journal of endodontics
Introduction Hydraulic calcium silicate cement-based sealers (CSC sealers) are now frequently used with warm vertical compaction in root canal treatment. However, the impact of heat on the biological properties of CSC sealers remains…
Nakano H, Shiinoki T · 2026 · Journal of neuro-oncology
PURPOSE: The radiosensitivity index (RSI) is a transcriptomic predictor of intrinsic radiosensitivity. The longitudinal behavior of the RSI in glioma and its variation across intratumoral cellular states have been unknown. We investigated…
Chang TP, Kuo YH, Bery AK · 2026 · Frontiers in neurology
Background Dizziness is common in older adults, and often presents a diagnostic challenge. Vestibular function declines with age, but the prevalence and diagnostic explanatory value of mild vestibular loss in isolation (i.e., the clinical…
Silva TR, Poínhos R, Oliveira BMPM et al. · 2026 · The British journal of nutrition
While rapid four-compartment (4C) models have demonstrated cross-sectional validity in diverse populations, including athletes, their longitudinal validity remains unverified. This study aims to evaluate the longitudinal validity of…
Hugueny J, de Ricolfis A, Johnson N et al. · 2025 · Thrombosis research
Objective This review aimed to synthesize recent data on venous thromboembolism (VTE) risk in the context of masculinizing hormone therapy with testosterone. Methods An electronic search was performed in MEDLINE/PubMed without date…
Rhodes J, Leach A · 2026 · Journal of sport & exercise psychology
Imagery is widely used in sport, but its effectiveness depends on how it is structured and the range of senses engaged. This study compared Functional Imagery Training-a multisensory, motivational intervention-with single-sense internal…
Anthuparambil ND, Timmermann S, Dargasz M et al. · 2026 · The Journal of chemical physics
The effect of lowered pH on the thermal gelation behavior of hen egg yolk was investigated over the temperature range of 58-72 °C using low-dose X-ray photon correlation spectroscopy in ultra-small-angle X-ray scattering geometry.…