Failed Experiment ReportMedicine
Bellissimo J, Hall B, Hali K et al. · 2026 · The Journal of arthroplasty
Background Orthobiologic therapies such as platelet-rich plasma (PRP), bone marrow aspirate concentrate (BMAC), and hyaluronic acid (HA) are increasingly offered for orthopaedic conditions, but their online promotion may not accurately…
View details →DOI: 10.1016/j.arth.2026.06.040 Negative / Null Result ReportOpen accessMedicine
La Vignera S, Condorelli RA · 2026 · International journal of molecular sciences
Incretin-based therapies, particularly glucagon-like peptide-1 receptor agonists (GLP-1 RAs), have emerged as potentially promising therapeutic agents for improving ovarian function, especially in women with polycystic ovary syndrome…
View details →DOI: 10.3390/ijms27114752 Negative / Null Result ReportOpen accessMedicine
Luo X, Wang B, Liu H et al. · 2026 · Integrative medicine research
Background Atopic dermatitis (AD) is a common chronic inflammatory skin disorder with substantial global burden. In some regions, Chinese medicine (CM) and integrated Chinese-Western medicine (ICWM) are widely used, but the overall…
View details →DOI: 10.1016/j.imr.2026.101359 Negative / Null Result ReportMedicine
Henriques JP, Weckwerth AVB, Santana ACP et al. · 2026 · Annales pharmaceutiques francaises
Objectives Diabetes mellitus and periodontal disease are highly prevalent chronic disorders linked by bidirectional inflammatory and oxidative pathways. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are emerging pharmacologic agents…
View details →DOI: 10.1016/j.pharma.2026.06.008 Negative / Null Result ReportOpen accessMedicine
Shukkoor AA, Turgeon RD, De Vera MA et al. · 2026 · BMJ open
Objectives This study aimed to investigate the association and potential causal relationship between ischaemic stroke/transient ischaemic attack (TIA) and oral anticoagulant (OAC) adherence using Bradford Hill's criteria and to determine…
View details →DOI: 10.1136/bmjopen-2025-112736 Negative / Null Result ReportOpen accessMedicine
Mohamed D, Ramadan AA, Mabrok HB et al. · 2026 · World journal of biological chemistry
Phytosterols are plant-derived sterols structurally similar to cholesterol and present in vegetable oils, seeds, legumes, and whole grains. Their best-established health effect is lowering circulating low-density lipoprotein cholesterol,…
View details →DOI: 10.4331/wjbc.v17.i2.121685 Negative / Null Result ReportMedicine
Lande-Brenner A, Ecker UKH, Mayo R · 2026 · Scientific reports
This research demonstrates that citing scientific sources to correct disinformation can be ineffective or even counterproductive, and offers a potential remedy. Three experiments simulated a WhatsApp conversation about COVID-19 vaccine…
View details →DOI: 10.1038/s41598-026-54720-9 Negative / Null Result Report
Günther A, Bednarczyk-Cwynar B, Malinowski M · 2026 · Preprint
Background: Type 2 diabetes mellitus is a progressive cardiometabolic disease in which many patients require treatment intensification despite lifestyle intervention and evidence-based pharmacotherapy. Oleanolic acid, a pentacyclic…
View details →DOI: 10.20944/preprints202606.1159.v1 Negative / Null Result Report
Edmar BA, Veen D, Klugkist I · 2026 · Preprint
Bayesian evidence synthesis (BES) provides a way of synthesising research without pooling effects, allowing for quantitative synthesise procedures when the more traditional common-effects and random-effects models cannot be used. BES can…
View details →DOI: 10.31234/osf.io/pwv54_v2 Negative / Null Result ReportMedicine
Gallardo LM · 2026 · The American journal of clinical hypnosis
Age regression represents a foundational technique in clinical hypnosis, yet its therapeutic mechanisms, clinical applications, and evidence base remain incompletely understood and subject to ongoing controversy. This integrative critical…
View details →DOI: 10.1080/00029157.2026.2679567 Negative / Null Result ReportOpen accessMedicine
Tomblin Murphy G, Sampalli T, Elliott Rose A et al. · 2026 · International journal of nursing studies advances
Introduction Despite the global shortage of nurses, there is limited literature that comprehensively maps interventions to support, stabilize, and enhance the nursing workforce. Purpose This umbrella review aimed to identify structures,…
View details →DOI: 10.1016/j.ijnsa.2026.100581 Negative / Null Result ReportMedicine
Kam KW, Mehraban Far P, Yim TW et al. · 2026 · The Cochrane database of systematic reviews
Rationale Blepharitis is a common ocular condition characterized by inflammation of the eyelid margins, which can cause irritating symptoms and ocular surface damage. Conventional treatment of blepharitis consists of eyelid hygiene and…
View details →DOI: 10.1002/14651858.cd013550.pub3 Negative / Null Result ReportMedicine
Garg A, Nakhla O, Steeper M et al. · 2026 · The Cochrane database of systematic reviews
Rationale Assisted reproductive technologies (ART), including in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI), combine an egg and sperm outside the body to enhance the probability of fertilisation and pregnancy.…
View details →DOI: 10.1002/14651858.cd010461.pub4 Negative / Null Result ReportMedicine
Weber I, Whelan BM, Bruce JM et al. · 2026 · Sports health
Context There is significant interest in jugular venous compression (JVC) devices from multiple parties, including sports physicians, athletic trainers, athletes, and parents. Objective To examine the effects of JVC on repetitive head…
View details →DOI: 10.1177/19417381261453672 Replication FailureOpen accessMedicine
· 2026 · Journal of cellular and molecular medicine
Retraction Z. Li and B. M. Pützer, "Spliceosomal Protein E Regulates Neoplastic Cell Growth by Modulating Expression of Cyclin E/CDK2 and G2/M Checkpoint Proteins," Journal of Cellular and Molecular Medicine 12, no. 6a (2008): 2427-2438.…
View details →DOI: 10.1111/jcmm.71228 Failed Experiment ReportMedicine
Taylor AJ, Miller BP, Copeland A · 2026 · Journal of the experimental analysis of behavior
Behavioral economic accounts posit that distorted valuation processes underlie cannabis decisions; however, less is known about the moment-to-moment dynamics through which value influences observable choice behavior. This study explored…
View details →DOI: 10.1002/jeab.70110 Replication FailureMedicine
Kim JH, Hwang YH, Kang E et al. · 2026 · Kidney research and clinical practice
Background Alport syndrome (AS) is a hereditary kidney disorder characterized by progressive hematuria, proteinuria, and kidney failure, frequently accompanied by hearing loss and ocular abnormalities. Although blockade of the…
View details →DOI: 10.23876/j.krcp.25.452 Replication FailureMedicine
Gross AR, Lee H, Chacko N et al. · 2026 · The Cochrane database of systematic reviews
Rationale Botulinum toxin type A (BoNT-A) intramuscular injections are commonly administered for neck pain unresponsive to other therapies, but the benefit-harm profile remains uncertain. Objectives To assess the benefits and harms of…
View details →DOI: 10.1002/14651858.cd008626.pub4 Negative / Null Result ReportMedicine
Mehta V, Galletti C, Mathur A et al. · 2026 · Systematic reviews
Background Oral candidiasis (OC) is among the most prevalent oral infections, frequently associated with immunosuppression, denture wearing, advanced age, and excessive antibiotic use. Given the growing concerns about antifungal…
View details →DOI: 10.1186/s13643-026-03249-z Negative / Null Result ReportMedicine
Wu X, Zhang B, Yu M et al. · 2026 · Photodiagnosis and photodynamic therapy
Repeated low-level red-light therapy (RLRL) has emerged as a promising ocular photobiomodulation strategy for childhood myopia control. Published randomized trials have reported substantial reductions in axial elongation and refractive…
View details →DOI: 10.1016/j.pdpdt.2026.105554 Failed Experiment ReportMedicine
Anarna K, Fiander M, Mitra S · 2026 · The Cochrane database of systematic reviews
Rationale Preterm and low-birthweight infants are at risk of anemia due to a variety of factors, including low levels of erythropoietin. They may therefore benefit from erythropoiesis-stimulating agents (ESAs). However, controversy remains…
View details →DOI: 10.1002/14651858.cd004863.pub7 Null DatasetMedicine
He Z, Yang L, Liang Z et al. · 2026 · NPJ digital medicine
Large language models (LLMs) are being deployed in clinical settings despite an underdeveloped evidence base regarding their real-world effectiveness. This study employed systematic evidence mapping to characterize outcome measures used in…
View details →DOI: 10.1038/s41746-026-02837-6 Negative / Null Result Report
Curran T, Pymm J, Gabriel J et al. · 2026 · Preprint
Abstract Cardiac fitness and rehabilitation programs offer meaningful benefits for individuals with congenital heart disease (CHD), and newer delivery models include hybrid formats combining virtual and in-person training. We hypothesized…
View details →DOI: 10.21203/rs.3.rs-10026873/v1 Negative / Null Result ReportMedicine
Ordóñez-Riaño S, Jiménez-Leal W · 2026 · Acta psychologica
What motivates people to place trust in strangers-the sense that they ought to trust, or the feeling that they want to? Competing perspectives suggest that trust may be driven either by obligations or by desires. In two studies, we tested…
View details →DOI: 10.1016/j.actpsy.2026.107099 Negative / Null Result Report
Seymore TN, Hoffmann S, Louro P et al. · 2026 · Preprint
Fetal health is heavily dictated by the maternal environment. Inhaling airborne pollutants, like particulate matter, is associated with pregnancy complications and fetal developmental pathologies, including fetal growth restriction (FGR).…
View details →DOI: 10.64898/2026.06.16.732724 Negative / Null Result ReportMedicine
De Laet H, Nijhof AD, Wiersema JR · 2026 · Autism : the international journal of research and practice
While prevailing theories suggest social interaction difficulties are inherent to autism, the theory of the double empathy problem (DEP) proposes these difficulties arise from a mismatch between different neurotypes. The theory predicts…
View details →DOI: 10.1177/13623613261451897 Negative / Null Result Report
Agarwal N, Rochat P · 2026 · Preprint
Across two experiments, children (N = 258, ages 4–10) evaluated protagonists who either protested unfair, arbitrary rules ("good trouble") or upheld the status quo. Study 1 demonstrates that from age 5, children prefer affiliating with…
View details →DOI: 10.31234/osf.io/kq9ds_v4 Negative / Null Result Report
Agarwal N, Rochat P · 2026 · Preprint
Across two experiments, children (N = 259, ages 4–10) evaluated protagonists who either protested unfair, arbitrary rules ("good trouble") or upheld the status quo. Study 1 demonstrates that from age 5, children prefer affiliating with…
View details →DOI: 10.31234/osf.io/kq9ds_v3 Negative / Null Result Report
Agarwal N, Rochat P · 2026 · Preprint
Across two experiments, children (N = 259, ages 4–10) evaluated protagonists who either protested unfair, arbitrary rules ("good trouble") or upheld the status quo. Study 1 demonstrates that from age 5, children prefer affiliating with…
View details →DOI: 10.31234/osf.io/kq9ds_v2 Negative / Null Result ReportMedicine
Kiang M, Lepock JR, Mizrahi R et al. · 2026 · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
Objectives Patients at clinical high risk (CHR) for schizophrenia experience a wide range of clinical outcomes. Given this heterogeneity, long-term prognostic biomarkers are needed. The gamma-frequency EEG auditory steady-state response…
View details →DOI: 10.1080/15622975.2026.2684757 