A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21379 results · page 674 of 713
Danböck SK, Hettegger S, Franke LK et al. · 2025 · Preprint
Background: Peritraumatic dissociation is thought to contribute to posttraumatic symptoms like intrusions and memory disturbances. However, trauma-analogue studies that examined effects of experimental dissociation-induction on intrusions…
Ilkovska B, Trifunova BK, Ilkovski F et al. · 2025 · Preprint
Abstract Background: Breast cancer (BC) is one of the most common malignancies among women worldwide, with approximately 2.3 million new cases and 685,000 deaths reported in 2020. Inflammation-related hematologic parameters—such as the…
Rezazadeh F, Lavaee F, Dezhkameh S et al. · 2025 · Preprint
Abstract Background: Lichen planus (LP), an inflammatory and chronic disorder, is immune-mediated and influences nails, skin, hair, and mucosal tissues. Autoimmune diseases affect females more commonly, and it is reported that there is an…
So R, Kariyama K, Oyamada S et al. · 2024 · Preprint
Objective To evaluate the effectiveness of screening and ultra-brief intervention (Ultra-BI) delivered by primary care physicians in less than 1 minute compared to simplified assessment only (SAO) for reducing alcohol consumption among…
Oliveira AHA, Paula DM, Serafini S et al. · 2026 · Acta cirurgica brasileira
Purpose To evaluate the effects of direct and remote ischemic preconditioning and postconditioning on kidney ischemia-reperfusion injury in young rats. Methods This study was divided into two experimental phases: preconditioning and…
Kesgin YM, Kaan AZ, Arslan M et al. · 2025 · World journal of emergency surgery : WJES
Background Textbook outcome (TO) is a concept that describes achieving an uneventful course for a patient undergoing surgery. It was first described for colorectal surgery and is now increasingly linked to various topics of surgical…
Ishimaru T, Aihara I · 2025 · The Journal of experimental biology
Male cicadas emit sounds to attract females. The acoustic traits of calls vary among species and show unique patterns that dynamically change, even in the same bout. While the calling behavior of a single cicada has been quantified for…
Francis AM, Anderson TJ, McKearney KJ et al. · 2025 · Psychiatry research. Neuroimaging
Cognitive impairment, particularly in attention and working memory, is a notable feature of schizophrenia (SZ). Individuals with SZ frequently consume high levels of caffeine, often exceeding 550 mg daily, yet the cognitive effects of this…
Yan J, Zheng W, Xie S et al. · 2025 · International dental journal
Introduction and aims Observational studies suggest an association between metabolic syndrome (MetS) and periodontitis. However, observational studies are susceptible to reverse causation and confounding factors, so the causality of this…
Zhang X, Liang S, Wang X et al. · 2025 · Preprint
Abstract Background Several special case of vitiligo patient with advanced pancreatic cancer was observed in our clinical practice, which prompted us to think about whether there is an association between the two diseases, and to further…
Nickerson C, Wright S, Pickering L et al. · 2025 · Journal of public health (Oxford, England)
Background Bowel cancer screening in England is initially carried out using a home testing kit, with those who require further testing first being referred to an assessment clinic. During COVID-19, these assessment clinics became 'virtual'…
Damtie Y, Betts K, Dachew BA et al. · 2025 · Journal of psychosomatic research
Background Limited evidence exists on the association between maternal use of antidiabetic medications and neurodevelopmental outcomes in children. This study examined the link between maternal diabetes, antidiabetic medication use, and…
Shen Y, Nishikawa K, Hiruta SF et al. · 2025 · Zoological science
The water mite genus Hygrobates and the newt family Salamandridae are distributed widely in the northern hemisphere. However, only in Eastern and Southeastern Asia a host-parasite association developed, with several Hygrobates species,…
Podoly TY, Even-Ezra H, Doron G · 2025 · Journal of affective disorders
Misophonia is a condition characterized by strong, aversive reactions to specific sounds produced by others, often manifesting as intense negative emotions like anger or rage in response to nearby noises. The present study aimed to…
Ala-Jaakkola R, Forssten SD, Cheng J et al. · 2025 · Molecular nutrition & food research
Functional constipation (FC) is characterized by difficult, infrequent, or incomplete bowel movements without clear physiological cause. Daily intake of Bifidobacterium lactis HN019 has been shown to reduce colonic transit time or…
El-Nagdy NK, Mansour NO, Diab AAA et al. · 2025 · Pharmacotherapy
Background Midodrine has been primarily studied as an adjunctive oral therapy to reduce the need for vasopressors in intensive care units (ICU). Nonetheless, the available results evaluating midodrine as an adjuvant therapy in the…
Barbakoff D, Glennie K, Yan M et al. · 2026 · Journal of applied gerontology : the official journal of the Southern Gerontological Society
Supportive environmental features (SEFs) are attributes of homes that help people overcome activity limitations. Evidence suggests that SEFs may facilitate aging in place. However, real-life SEF implementation patterns are not fully…
Mest J, Flood A, Preston P et al. · 2026 · Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine
Objectives To investigate if sensorimotor function predicts pain-related cognition in people with lower limb tendinopathy. Design Single-cohort, cross-sectional study. Setting Sports and exercise research laboratory. Participants…
Rilveria JRC, Grepo LC, Lim PMQ et al. · 2026 · Npj mental health research
Mental health mobile applications are increasingly used to address psychological distress and promote well-being, yet evidence on how and when these tools exert their effects over time and what constitutes meaningful engagement remains…
Cotet M, Poensgen D, Krajbich I · 2026 · Preprint
Learning is fundamental to adaptive behavior. In the typical learning task, each action is associated with only one outcome, which could be immediate or delayed. However, actions often have multiple consequences that unfold over time.…
Zhang S, Song Y, Steptoe A et al. · 2026 · Psychology of sport and exercise
Previous research has demonstrated a link between physical activity and loneliness, though the direction of this relationship remains unclear. This study explored daily fluctuations in the temporal relationship between physical activity…
Hill TG · 2026 · Preprint
Healthy personality profiles, characterized by higher extraversion, agreeableness, conscientiousness, and openness alongside lower neuroticism, are often assumed to support broad flourishing across the life course. Yet it remains unclear…
· 2024 · Journal of cellular and molecular medicine
Xin Li, Hao Xu, Jianfeng Yi, Chunlu Dong, Hui Zhang, Zhengfeng Wang, Long Miao, Wence Zhou. miR-365 secreted from M2 Macrophage-derived extracellular vesicles promotes pancreatic ductal adenocarcinoma progression through the BTG2/FAK/AKT…
Power MC, Lynch KM, Fang V et al. · 2025 · Environmental research
Background As dementia has a decades-long preclinical phase, earlier air pollution exposures may be more etiologically relevant to dementia risk than more recent exposures. Methods We estimated exposures at Atherosclerosis Risk in…
Kömürcü HF, Sever N, Gökdereli NS et al. · 2025 · Neurological research
Background It has been suggested that smokers have higher recanalization rate, lower risk of cerebral hemorrhage and better prognosis than non-smokers (smoking paradox) after reperfusion therapy in patients with acute ischemic stroke (IS).…
Andersen Z, Kilgore S, Waite-Cusic J et al. · 2025 · Journal of Dairy Science
Hispanic-style cheeses (HSC), particularly fresh soft varieties, have been associated with numerous outbreaks of Listeria monocytogenes, highlighting the need to identify product characteristics or interventions that could mitigate L.…
Xu C, Yang G, Liu Y · 2024 · Preprint
Abstract Background Obstructive Sleep apnea (OSA) is a prevalent sleep disorder characterized by repetitive interruptions of breathing during sleep, significantly impacting cardiovascular and metabolic health. Epigenetic aging, measured…
Toyoshima M, Toyofuku R, Shimoda S et al. · 2026 · Neuropsychopharmacology reports
Adolescence is a sensitive developmental stage in which exposure to addictive substances can produce long-lasting changes in the neural circuits that regulate reward. Nicotine and ethanol are frequently co-used among adolescents, and…
McVige J, Masset L, Mechtler L et al. · 2026 · Journal of child neurology
Mass psychogenic illness (MPI), also known as mass sociogenic illness, is a functional neurologic symptom disorder affecting multiple people simultaneously. This study presents a pediatric MPI outbreak involving abrupt-onset tics in LeRoy,…
Ferreira HRS, Hadden AC, Champagnon J et al. · 2025 · The Science of the total environment
Despite the vital importance of wetlands globally, these habitats have increasingly received anthropogenic materials, such as plastics, which can impact the wildlife these habitats support. Despite commonly found in the nests of Eurasian…