Negative / Null Result ReportMedicine
An MH, Kim C, Min K et al. · 2026 · Discover oncology
Background The ProtecT randomized trial found similar survival between active surveillance (AS), radiotherapy (RT), and radical prostatectomy (PT) in localized prostate cancer (PC), but observational studies yielded conflicting results.…
View details →DOI: 10.1007/s12672-026-05392-4 Replication FailureMedicine
Kundu A, Khan A, Saha S et al. · 2026 · Journal of perioperative practice
Background Effective patient education materials on prehabilitation are essential for optimising patients before surgery. With the growing use of generative artificial intelligence (AI) chatbots in health care communication, it is…
View details →DOI: 10.1177/17504589261454163 Negative / Null Result Report
li j, Chen Y, Chen Y et al. · 2026 · Preprint
Abstract Objective To investigate the association between perioperative hypothermia and postoperative muscular calf vein thrombosis (MCVT) in patients undergoing total knee arthroplasty (TKA), and to evaluate the predictive performance of…
View details →DOI: 10.21203/rs.3.rs-9873445/v1 Negative / Null Result ReportMedicine
Doğan D, Öksüz C, Çakır Ö et al. · 2026 · Biomedicines
Background/Objectives: Differentiating mediastinal lymphadenopathy associated with lung cancer from sarcoidosis remains a clinical challenge because of overlapping imaging findings. This study evaluated whether CT-derived radiomic…
View details →DOI: 10.3390/biomedicines14061327 Negative / Null Result ReportOpen accessMedicine
Xie B, Rui Y · 2026 · Plants (Basel, Switzerland)
Nanotechnology has attracted increasing attention in agricultural and environmental research, but the biological effects and potential risks of nanoparticles based on non-essential elements remain insufficiently understood. This study…
View details →DOI: 10.3390/plants15111727 Negative / Null Result Report
Potdar A, Kumari A · 2026 · Preprint
Abstract Solar radio bursts in the metric and decametric ranges are direct signatures of accelerated electrons in the solar atmosphere. It is almost always the case that these bursts are associated with solar flares. In the present study,…
View details →DOI: 10.21203/rs.3.rs-9628976/v1 Failed Experiment ReportOpen accessMedicine
Fouad S, Abass M, Rizk A et al. · 2026 · Scientific reports
Epidural fibrosis (EF) refers to the non-physiological scar formation at the site where a surgical incision is made to access the spinal canal. This condition often results in functional disability and pain following spinal surgery and is…
View details →DOI: 10.1038/s41598-026-54270-0 Negative / Null Result ReportMedicine
Destro JM, Reis BO, Chrisostomo DA et al. · 2026 · Journal of functional biomaterials
This study aimed to evaluate the effects of experimental bioactive glass solutions on dentinal fluid flow and hydraulic conductance in vitro. Dentin blocks of 50 bovine incisors were divided into 5 groups according to the desensitizing…
View details →DOI: 10.3390/jfb17060302 Negative / Null Result ReportOpen accessMedicine
Xu Z, Su S, Xu Z et al. · 2026 · Frontiers in psychology
The Drive for Muscularity Attitudes Questionnaire (DMAQ) is a brief tool for assessing muscularity-related attitudes. This study translated the DMAQ into Chinese and evaluated its reliability and validity separately in males and females. A…
View details →DOI: 10.3389/fpsyg.2026.1732786 Negative / Null Result ReportMedicine
Koyuncu Z, Evcil FY, Kilimci ÖS et al. · 2026 · BMC psychiatry
Objective This study investigated whether current comorbid psychiatric symptoms were involved in statistical indirect associations between childhood attention-deficit/hyperactivity disorder (ADHD) symptoms (CAS) and functional impairment…
View details →DOI: 10.1186/s12888-026-08299-0 Negative / Null Result Report
Hirano K, Seki T, Watanabe A et al. · 2026 · Preprint
Background Initiation of emergency dialysis, often requiring temporary catheter owing to unprepared definitive vascular access, is associated with infectious and vascular complications and suggests advanced chronic kidney disease (CKD)…
View details →DOI: 10.64898/2026.06.21.26356128 Negative / Null Result ReportMedicine
Gessler KB, Rescaroli J, Pires SM et al. · 2026 · Neurotoxicity research
Atorvastatin is a widely prescribed statin used for its cholesterol-lowering effects; however, it also exerts known pleiotropic effects, including antioxidant and anti-inflammatory properties. Atorvastatin´s impact on mitochondrial…
View details →DOI: 10.1007/s12640-026-00805-2 Negative / Null Result Report
Pan Y, Sun Y, Shi C et al. · 2026 · Preprint
Abstract Genetic testing guides personalized management of differentiated thyroid carcinoma (DTC). However, tumor heterogeneity, including spatial and temporal heterogeneity, has created an unresolved clinical problem. It remains unclear…
View details →DOI: 10.21203/rs.3.rs-9922971/v1 Negative / Null Result ReportMedicine
Tuo Y, Yang S, Dai X et al. · 2026 · Journal of ethnopharmacology
Ethnopharmacological relevance Syringa oblata Lindl. emits a variety of biogenic volatile organic compounds (BVOCs) during full bloom, which forms the key chemical basis for its characteristic floral scent. Species of the genus Syringa…
View details →DOI: 10.1016/j.jep.2026.122022 Negative / Null Result ReportMedicine
Zhen B, Yang X, Yao B · 2026 · Scandinavian journal of psychology
Child abuse has been significantly associated with children's mobile phone dependence (MPD), particularly in left-behind children (LBC). However, whether distinct forms of child abuse (physical and emotional) are associated with MPD in LBC…
View details →DOI: 10.1111/sjop.70119 Negative / Null Result ReportOpen access
Idawati, I. (Idawati), Wahyudi, W. (Wahyudi), Endang, B. (Busri) · 2016
In this research method used is quantitative method, the type of comparative studies, to compare existing organizational culture in school achievement. Data used primary data. The results showed that (1) There is no significant difference…
Negative / Null Result ReportOpen access
Huaizhou You (414624), Chuanming Hao (124404), Ying Zhou (25031) et al. · 2013
(a1) Failure plots for probability of survival at 90 days between high and low 25-hydroxyvitamin D level subgroups. No significant difference between the two subgroups was found (log rank, p = 0.554). (b1) Failure plots for probability of…
View details →DOI: 10.1371/journal.pone.0064964.g004 Failed Experiment ReportMedicine
Lambert M, Wambacq E, Devlamynck R et al. · 2026 · Plants (Basel, Switzerland)
Duckweed (Lemnaceae) is a promising alternative feed crop, particularly in regions with nutrient surpluses and protein deficits, as it grows efficiently on nutrient-rich agricultural wastewater and provides protein-rich biomass. However,…
View details →DOI: 10.3390/plants15121865 Negative / Null Result ReportMedicine
Partoazar A, Shahabi S, Afrasiabi S · 2026 · BMC oral health
Background Biofilms contribute to the dental calculus formation, which in turn deteriorates oral and systemic health. The use of antimicrobial photodynamic therapy (PDT) may be limited by problems with photosensitizer penetration. In…
View details →DOI: 10.1186/s12903-026-09022-x Negative / Null Result ReportMedicine
Lipa AJ, Janata-Schwatczek K, Sterz M et al. · 2026 · Seminars in thrombosis and hemostasis
Pulmonary embolism (PE) in octogenarians (i.e., patients > 80 years) is associated with substantial morbidity and mortality, yet this population remains underrepresented in major studies. We compared the predictive performance of the…
View details →DOI: 10.1055/a-2896-8297 Negative / Null Result ReportMedicine
Chen W, Ge X, Hu C et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Prospective studies are necessary to determine the association between circulating proteins and colorectal cancer (CRC) risk, offering non-invasive biomarkers for early CRC risk prediction and interventions. The Olink Explore-3072 platform…
View details →DOI: 10.1158/1055-9965.epi-26-0341 Negative / Null Result ReportMedicine
Umer H, Mumtaz T, Weiskirchen R et al. · 2026 · Chronobiology international
Disruption of circadian rhythm is common in rotating shift workers, individuals with jet lag, and people with irregular sleep schedules and contributes to metabolic diseases including obesity, type 2 diabetes, metabolic…
View details →DOI: 10.1080/07420528.2026.2681614 Negative / Null Result ReportMedicine
Liu Y, Tao G, Zhao Y et al. · 2026 · Frontiers in medicine
Objective To characterize choroidal structural and perfusion changes in children with emmetropia, low myopia, and moderate myopia using enhanced depth imaging optical coherence tomography (EDI-OCT) and optical coherence tomography…
View details →DOI: 10.3389/fmed.2026.1861658 Negative / Null Result ReportMedicine
Kurogochi K, Stern JA, DeFrancesco TC et al. · 2026 · Journal of the American Veterinary Medical Association
Objective The T-wave peak-end (TpTe) interval and its ratio to the QT interval (TpTe:QT) are ECG markers of myocardial repolarization dispersion. We hypothesized that these markers are associated with echocardiographic indices reflecting…
View details →DOI: 10.2460/javma.25.12.0802 Negative / Null Result ReportOpen accessMedicine
Eydou Z, Garber S, Sikkema M · 2026 · Cureus
Fusobacterium necrophorum is a recognized cause of brain abscesses and has been classically associated with Lemierre syndrome. We report a case of a 17-year-old male patient who presented with seizures, fever, and altered mental status…
View details →DOI: 10.7759/cureus.108808 Negative / Null Result Report
Szeto CYY, Kwan HS · 2026 · Preprint
Dietary and lifestyle microbiome interventions often produce mild but heterogeneous remodeling rather than uniform community shifts. In this setting, scalar diversity or group-level summaries can appear weak or inconclusive even when…
View details →DOI: 10.64898/2026.05.22.726133 Abandoned HypothesisMedicine
Jia W, Yang D, Yu S · 2026 · Computer methods in biomechanics and biomedical engineering
Melasma is a common acquired pigmented dermatosis, which seriously affects the appearance and quality of life of patients. Calreticulin (CALR) is a pleiotropic protein existing in nucleated cells, which mediates cellular immunity, and…
View details →DOI: 10.1080/10255842.2026.2689709 Replication FailureMedicine
Hölscher C · 2026 · Journal of Alzheimer's disease : JAD
BackgroundSemaglutide is a glucagon-like peptide-1 analog that is on the market to treat type 2 diabetes and weight loss (Ozempic, Wegovy). Two phase 3 clinical trials have been conducted, Evoke and Evoke+, testing the drug in patients…
View details →DOI: 10.1177/13872877261458402 Negative / Null Result ReportOpen accessMedicine
Boualia B, Sandeli A, Boulebd H et al. · 2026 · ACS omega
In this research, we present the successful synthesis of benzimidazolium salts ( 2a - e ) and their corresponding selenium-NHC adducts ( 3a - e ), achieved with satisfactory yields ranging from 75% to 88%, and characterized using…
View details →DOI: 10.1021/acsomega.5c10880 Negative / Null Result ReportOpen accessMedicine
Qaid MM, Al-Garadi MA, Al-Abdullatif AA et al. · 2026 · Poultry science
Coccidiosis remains a major constraint in poultry production; therefore, this study evaluated the anticoccidial efficacy of a phytogenic blend of cinnamon bark and Rumex nervosus leaf in Eimeria tenella-challenged broilers. Birds were…
View details →DOI: 10.1016/j.psj.2026.107288