A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21368 results · page 649 of 713
Wang H, Loke JY, Chan WO et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives: Increased axial length is a major risk factor for retinal detachment. This study explored whether, in individuals presenting with unilateral disease, the longer eye was more likely to have rhegmatogenous disease.…
Abudurehemu S, Wang X, Wang J et al. · 2026 · BMC women's health
Objective The purpose of this study was to compare the efficacy of cold-knife conization (CKC) and loop electrosurgical excision procedure (LEEP) in treating cervical adenocarcinoma in situ (AIS) and identify relevant risk factors within a…
Yousef EM, Eldemerdash OM, Senousy MA et al. · 2026 · Neural plasticity
Dexmedetomidine (Dex), an α2-adrenergic receptor agonist, and apigenin (Api), a naturally occurring bioflavonoid, have recently shown neuroprotective effects in experimental models of methotrexate (MTX)-induced neurotoxicity; however, the…
Temiztürk Z, Beyazal OF, Topçu AC et al. · 2026 · Brazilian journal of cardiovascular surgery
Introduction The aim of our study is to investigate the relationship and predictive significance of routinely measured serum lactate values with postoperative atrial fibrillation (POAF) in patients following isolated coronary artery bypass…
Eveson TE, Davis TP, Tindall AJ · 2026 · Journal of orthopaedics
Background Accurate medio-lateral sizing of the distal femur during total knee replacement (TKR) is essential to optimise implant fit and avoid over- or under-hang, which have been associated with suboptimal outcomes. National guidance…
Icoz M, Aktas Ozaltun O · 2026 · Clinical ophthalmology (Auckland, N.Z.)
Purpose To compare the refractive effects of paired-opposite clear corneal incision (p-OCCI) with-the-rule (WTR), against-the-rule (ATR) and oblique astigmatism. Methods This retrospective study was conducted in 131 patients undergoing…
Hu Z, Ma R, Wen Y et al. · 2026 · Cancer medicine
Background The optimal therapeutic strategy for patients with T2-3N0-3 M0 or T1N1-3 M0 hypopharyngeal squamous cell carcinoma (HPSCC) and the use of postoperative radiotherapy with or without systemic therapy for patients with T1-2N1M0…
Kassem BA, Osman SM, El-Mahallawy Y · 2026 · Clinical oral investigations
INTRODUCTION: The stimulatory effects of laser Biostimulation on immediate implant clinical wound healing and radiographic bone quality analysis is with insufficient evidence. AIM: To evaluate the effect of low-level diode laser as a…
Li H, Ding S, Li J et al. · 2026 · Frontiers in medicine
Background The incidence of elderly-onset ulcerative colitis (EO-UC) has been gradually increasing. The unique characteristics of clinical manifestations, therapeutic strategies, and prognosis in EO-UC patients compared with adult-onset…
Zhang HM, Wu MX, Wang HY et al. · 2026 · Zhonghua yi xue za zhi
Objective: To explore the mechanism of vitamin K2 (VitK2) regulating matrix Gla protein (MGP) in inhibiting tumor growth in inflammation-associated colorectal cancer (CAC) model mice. Methods: Twenty-six C57BL/6 male mice, 6-8 weeks old…
Pusdekar VP, Dare G, Bhojwani P et al. · 2026 · Turkish journal of surgery
Objective Surgical site infections (SSIs) are among the most common postoperative complications, contributing to morbidity, prolonged hospital stays, and healthcare costs. Prophylactic antibiotics are widely used, but the optimal regimen…
Toufexis C, Grant JB, van Boxtel JJA et al. · 2026 · Consciousness and cognition
The left angular gyrus (AG) has been implicated in the level of detail elicited during both episodic memory (EM) and episodic future thinking (EFT). This study aimed to investigate whether repetitive transcranial magnetic stimulation…
Brzóska K, Carpenter AD, Petrus SA et al. · 2026 · International journal of molecular sciences
Gamma-tocotrienol (GT3) is one of the constituents of vitamin E that demonstrated significant radioprotective efficacy in murine and nonhuman primate (NHP) models. Considering the antioxidant activity of GT3 and its role in terminating…
Ha S, Kwon H, Namgoong JM et al. · 2026 · Annals of surgical treatment and research
Purpose In the past decade, advancements in robotic surgery have significantly expanded its application into diverse fields, including urological, gastrointestinal, hepatobiliary, and gynecological procedures. However, comparative outcome…
Samiei A, Najafabadi ZH, Akbari N et al. · 2026 · Journal of applied genetics
INTRODUCTION: Optimized vectors are crucial in modern molecular biology because they greatly enhance the efficiency of the DNA cloning procedure. This study aimed to design a novel engineered vector containing an HphI cassette to enhance…
Safoora AK, Vadakkepurayil K, Santhakumar M · 2026 · International journal of clinical pediatric dentistry
Background and objectives Dental anxiety is frequently observed in children and often poses a significant challenge to providing effective and high-quality dental care. Managing a child's anxiety in the clinical setting is a critical…
Ferencz A, Lőrinczy D · 2026 · Biology
Beyond gas transport, red blood cells (RBCs) have emerging roles regarding innate immunity, regulating blood flow, and participating in nutrient transport, which can be engineered as drug delivery systems since they contribute to…
Lee J, Russell KW, Smith C et al. · 2026 · Annals of surgery
Objective Anastomotic stricture (AS) is the most common complication following repair of type C esophageal atresia with distal tracheoesophageal fistula (EA/TEF). Retrospective studies suggest transanastomotic tube (TT) use may increase AS…
Tan SYT, Liang TR, Chua JKL et al. · 2026 · Journal of clinical medicine
Background: The benefits of metabolic bariatric surgery (MBS) in people with a body mass index (BMI) ≥ 50 kg/m 2 are not well-established, with concerns of increased risk and poorer weight loss. The optimal surgical type (gastric bypass…
Bolçocuk D, Sürücüoğlu MS · 2026 · Journal of health, population, and nutrition
Background Nutrition literacy has been increasingly recognized as a fundamental determinant of healthy eating behaviors during adolescence. Adolescence is a critical phase for growth and adoption of long-term healthy habits. However, there…
Zou XC, Wu ZH, Xu XD et al. · 2026 · World journal of surgical oncology
Background and purpose As an emerging interactive display technology, mixed reality(MR) allows for the integration of multi-dimensional virtual objects with the real world, enhancing the precision of surgical operations. This technology…
Azizian A, Bernhardt M, Rühlmann F et al. · 2026 · BMC cancer
Background Resection of the periadventitial neurolymphatic tissue around the superior mesenteric artery (SMA) is considered a crucial component of oncologically complete resection in pancreatic head and corpus carcinomas. However, a…
Churproong S, Metcalfe B, Mcguigan P et al. · 2026 · Frontiers in rehabilitation sciences
Background Myofascial trigger points (MTrPs) are the cause of pain from myofascial pain syndrome (MPS), frequently in the trapezius muscle (TM). Working adults often avoid treatment due to the need for therapist assistance and limited…
Kim CH, Kim EJ, Lee TS et al. · 2026 · Oncology
Background Elderly patients or those with poor performance status are underrepresented in clinical trials of pancreatic ductal adenocarcinoma (PDAC), and optimal treatment strategies for this frail population remain unclear. In real-world…
Awawdeh L, Almesleh B, Hammouri H et al. · 2026 · Clinical oral investigations
Objectives The present study evaluated clinically and radiographically the effectiveness of Regenerative endodontic procedures (REPs) using platelet-rich fibrin (PRF) versus induced bleeding (IB) in treating mature necrotic teeth.…
Yıldırım Y, Arabacı R, Rodoplu C et al. · 2026 · Scientific reports
Investigating how the autonomic functions of the heart are affected during rapid weight loss practices is extremely important for athletes’ health. This study aimed to investigate how rapid weight loss (3–5%) affects heart rate variability…
Karaca S, Yilmaz OF, Sarmis A et al. · 2026 · Journal of ophthalmology
Objective To compare microbial contamination between multidose brimonidine eye drops preserved with benzalkonium chloride (BAK-MDB) and multidose brimonidine eye drops preserved with Purite® (PUR-MDB) using a comparative approach on the…
Irie M, Okada M, Maruo Y et al. · 2026 · Polymers
This study evaluated eleven resin cements used as core build-up materials by examining the following properties: (a) push-out force between root dentin and the fiber post; (b) pull-out force between the fiber post and the core build-up…
Cao Y, Zhu H, Wu J · 2026 · Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
Background Ultrasound-guided prostate biopsy is the standard method for the diagnosis of prostate cancer. However, the effect of the optimal puncture approach on diagnostic yield and patient outcomes remains controversial. Objective To…
Zeilinger J, Palkovits S, Ruiss M et al. · 2026 · American journal of ophthalmology
Purpose To compare intraindividual differences in visual performance of two refractive extended-depth-of-focus (EDF) intraocular lenses (IOLs) targeted for emmetropia. Design Prospective, randomized, patient- and examiner-masked…