A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19915 results in Negative / Null Result Report · page 646 of 664
Stevens, Bieber, Sanders et al. · 2026 · Proceedings (Baylor University. Medical Center)
This study provides a detailed evaluation of the effect preoperative embolization of spinal metastases has on reducing intraoperative blood loss (IBL) and the need for transfusion of packed red blood cells. A systematic search for all…
Abdelmaksoud, Hevessy, Bedekovics et al. · 2026 · EJHaem
Clinical benefit measures and surrogates for leukaemic transformation or overall survival are scarce in MF. Circulating myeloblast (CMB) counts have the biological plausibility to indicate disease evolution, but they are still determined…
Arslan, Tufekci, Acar et al. · 2026 · International urogynecology journal
This study aimed to examine the effects of tele-Pilates exercise on menopausal symptoms, quality of life, depression, and anxiety levels in postmenopausal women. Forty postmenopausal women were separated into two groups: as tele-Pilates…
Linton, Sjaarda, Hossenbaccus et al. · 2026 · The Journal of allergy and clinical immunology
The role of the nasal microbiome in allergic rhinitis (AR), particularly following direct allergen exposure using a controlled model, is incompletely understood. Understanding microbiome dynamics after allergen challenge could provide…
Haughey, Samara, Al-Rifai et al. · 2026 · BMJ paediatrics open
To investigate a unique, multicultural population to allow us to examine the association of ethnicity, socioeconomic status (SES) and spoken language at home on performance using developmental assessment tools. Analysis of a prospective…
Beato, Allen, Jamil et al. · 2026 · Journal of strength and conditioning research
Beato, M, Allen, M, Jamil, M, and Vicens Bordas, J. Three-season analysis of physical performance in professional English football: Influence of match outcome, match location, and players' position during official competitions. J Strength…
Hagele, Sunderland, Mumford et al. · 2026 · Nutrients
The purpose of this study was to examine the effects of acute dietary nitrate (NO 3 - ) and caffeine (CAF) supplementation on end power (EP) and work performed above EP (WEP) in trained male cyclists during a 3 min all-out test (3MT) on a…
Waldron, Suttawireesan, Fatimah et al. · 2026 · Journal of neuroendocrinology
Sex differences have been noted in the prevalence and severity of several neurological and mental health disorders. Midbrain dopaminergic activity is implicated in the etiology of many of these disorders and therefore may also contribute…
Zhang, Di, Qiao et al. · 2026 · BMC oral health
BACKGROUND: Bioceramic sealers have been increasingly applied in endodontics due to their excellent sealing properties and biocompatibility. However, the sealing performance of different bioceramic sealers and their removability during…
Lee, Chao, Shen et al. · 2026 · BMC pulmonary medicine
BACKGROUND: The optimal surgical strategy for very elderly patients (≥ 75 years) with stage I non–small cell lung cancer (NSCLC) remains uncertain. METHODS: We retrospectively analyzed 390 patients with pathologic…
Nesova, Vorobeva, Ryabov · 2026 · The Indian journal of medical research
Background and objectives The risk-treatment paradox (RTP) has not been studied in very high-risk patients with non-ST-elevation acute coronary syndrome (NSTE-ACS). We aimed to describe the cohort of very high-risk NSTE-ACS patients,…
Tavares, Ramalho, da Silva et al. · 2026 · Breast cancer research and treatment
Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by early relapse and limited therapeutic options. Carboplatin added to anthracycline/taxane neoadjuvant chemotherapy (NACT) raises pathologic complete response…
Caldonazo, Scheler, Fischer et al. · 2026 · American heart journal plus : cardiology research and practice
Device-associated endocarditis is a potentially life-threatening condition that typically requires the removal of the cardiac implantable electronic device (CIED). The role of routine coronary angiography (CAG) as part of preoperative…
Alzraikat, Al-Hiyasat, Jamous et al. · 2026 · Biomaterial investigations in dentistry
This study evaluated the effectiveness of acids on calcium silicate cement surface hardness, perforation, and their impact on root dentine microstructure. Root dentine discs were exposed to hydrochloric, acetic, and citric acids. Fourier…
Chen, Ma, Zhang · 2026 · Accident; analysis and prevention
Automated vehicles (AVs) are designed to improve traffic safety, mobility, and driver comfort; however, their benefits depend on the widespread adoption of AVs. As full market penetration remains unlikely in the near term, AVs will…
Atef Abdelsattar Ibrahim, Gouda Kamal, Zid et al. · 2026 · World journal of clinical pediatrics
Obesity and overweight are major public health challenges and are associated with autonomic imbalance and decreased heart rate variability (HRV), a non-invasive indicator of cardiovascular risk. Omega-3 polyunsaturated fatty acids have…
Yıldız, Top, Yıldız et al. · 2026 · Mediterranean journal of hematology and infectious diseases
Stenotrophomonas maltophilia ( S. maltophilia ) is a multidrug-resistant pathogen frequently isolated in hospital-acquired pneumonia and represents a significant clinical challenge. This study aimed to investigate the risk factors…
Timothee, Bliss, Blumenthal et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
The primary objective is to determine whether patients undergoing osseous microvascular free flap reconstruction of head and neck defects have higher inpatient pain requirements than those undergoing nonosseous reconstruction. Secondary…
Kacar, Ayaz-Alkaya · 2026 · Journal of pediatric nursing
Internet addiction is a growing problem among children and adolescents. Pathological internet use may lead to psychological and social issues. More effective and innovative interventions are needed to promote the mental health of children.…
Lopes, Costa, Nociti Junior et al. · 2026 · Brazilian oral research
This study investigated the effects of incorporating 3wt% titanium dioxide nanotubes (nTiO2) into calcium hydroxide [Ca(OH)2]-based intracanal medicament (ICM) formulations on the proliferation, viability, and mitochondrial metabolic…
Linke, Mayer, Suttkus et al. · 2026 · Pediatric research
This study examined parental stress indicators during outpatient pediatric surgery and whether intraoperative text messaging could alleviate stress. This randomized trial assigned parents of children aged 6 months to 6 years undergoing…
Melnikova · 2025 · Bulletin of experimental biology and medicine
Using in vivo microscopy, changes in the diameter of pial arterial microvessels were studied in rats with modeled moderate acute blood loss followed by whole-body cooling against the background of a single administration of tranexamic acid…
Nazki, Tennakoon, Reddy et al. · 2026 · The Journal of general virology
Infectious bursal disease virus (IBDV) causes an endemic immunosuppressive disease in chickens. Prior exposure to IBDV influences the pathogenesis and shedding of chicken strains of influenza A virus (IAV), but its effect on waterfowl…
Tuncekin, Toprak · 2026 · Iranian journal of immunology : IJI
Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are chronic autoimmune inflammatory disorders in which TNF-α plays a key role. Anti-TNF agents are widely used in the management of these diseases. Since TNF-α is also…
Xu, Hu, Zhao et al. · 2026 · Obesity (Silver Spring, Md.)
HDM1002, a small-molecule agonist of glucagon-like peptide-1 receptors, was evaluated for safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD). Chinese participants (18-60 years) with…
Elgayar · 2026 · Scientific reports
This trial aimed to explore the effect of supervised breathing exercises (BEs) on depression, sexual function, and exercise capacity in postmenopausal women. Sixty-four depressed postmenopausal women with associated sexual dysfunction were…
Rezaeinejad, Sepidarkish, Moini et al. · 2026 · Pregnancy hypertension
While cigarette smoking has been paradoxically associated with a reduced risk of preeclampsia, the effect of waterpipe (WP) smoking, an increasingly prevalent form of tobacco use remains poorly understood. This study aimed to investigate…
Ehne, Kastensson, Wedin et al. · 2026 · Journal of bone oncology
The use of postoperative radiotherapy (PORT) as an adjunct to orthopaedic surgery of the long bones is widely recommended. Evidence of the benefits is however sparse. The primary research question of this study was whether PORT reduces the…
Karunayawong, Sukmanee, Butchon et al. · 2026 · BMJ open
Since 1985, the international healthcare community has recommended the ideal rate of caesarean section (CS) to be 10%-15% at the national level. The literature has reported that overused CS without necessary medical indications can be…
Rodrigues, Macedo, de Paulo et al. · 2026 · Oral surgery, oral medicine, oral pathology and oral radiology
To evaluate the effects of sticky bone a biomaterial composed of Solid-PRF (S-PRF), a variant of platelet-rich fibrin (PRF), and deproteinized bovine bone-on bone formation after tooth extraction performed prior to radiotherapy, with…