Negative / Null Result ReportMedicine
Nielsen MK, Bartholdy ID, Kristensen KS et al. · 2025 · Veterinary parasitology
Equine strongylids are ubiquitous and can cause severe health issues. Anthelmintic resistance is widely common in cyathostomin parasites, and recent studies have documented increasing incidence of resistance to the macrocyclic lactone drug…
View details →DOI: 10.1016/j.vetpar.2025.110465 Negative / Null Result ReportMedicine
MacCarrick G, Aradhya S, Bailey M et al. · 2024 · American journal of medical genetics. Part A
Molecular genetics enables more precise diagnoses of skeletal dysplasia and other skeletal disorders (SDs). We investigated the clinical utility of multigene panel testing for 5011 unrelated individuals with SD in the United States…
View details →DOI: 10.1002/ajmg.a.63646 Negative / Null Result ReportOpen accessMedicine
Karvasarski E, Park J, Savaris S et al. · 2026 · CJC open
Background Resting hemodynamic assessment of suspected pulmonary hypertension (PH) in older adults with cardiovascular risk factors may not effectively discriminate pre-capillary from post-capillary disease. Exercise right-heart…
View details →DOI: 10.1016/j.cjco.2026.02.005 Negative / Null Result ReportMedicine
Crabtree D, Seidler K, Barrow M · 2025 · Clinical nutrition ESPEN
Background and aims Epidemiological studies have associated reduced bacterial diversity and abundance and food allergy. This mechanistic review investigated the link between gut dysbiosis and food allergy with a focus on the role of…
View details →DOI: 10.1016/j.clnesp.2024.11.019 Negative / Null Result ReportOpen accessMedicine
Portillo-Gallo JH, Sánchez-González JM, Saldaña-Cruz AM et al. · 2026 · Current issues in molecular biology
Pre-eclampsia is a Hypertensive Disorder of Pregnancy (HDP) characterized by hypertension and proteinuria, affecting 2-8% of pregnancies worldwide and constituting a major public health concern. Genes of the renin-angiotensin system have…
View details →DOI: 10.3390/cimb48020168 Negative / Null Result ReportOpen accessMedicine
Beissat K, Lattard V, Picard-Meyer E et al. · 2025 · PloS one
Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, a wide range of animal species (pets, mink…) have been naturally infected with this betacoronavirus. The emergence of new variants has…
View details →DOI: 10.1371/journal.pone.0316882 Negative / Null Result ReportOpen accessMedicine
Xie J, Jiang Y, Zhou Y et al. · 2024 · Maternal-fetal medicine (Wolters Kluwer Health, Inc.)
Objective To conduct a hierarchical classification analysis of the nonreportable results of noninvasive prenatal testing in an attempt to reduce failure rates and provide pregnant women with accurate information to alleviate their anxiety.…
View details →DOI: 10.1097/fm9.0000000000000248 Negative / Null Result ReportMedicine
Abdo M, Kunisaki KM, Morris A et al. · 2026 · AIDS research and human retroviruses
People aging with HIV (PAWH) experience greater impairment in physical and pulmonary function than individuals aging without HIV. We examined whether baseline physical function was associated with subsequent pulmonary impairments.…
View details →DOI: 10.1177/08892229261448283 Negative / Null Result ReportMedicine
Patchen BK, Best CM, Boiteau J et al. · 2025 · The Cochrane database of systematic reviews
Background Randomised controlled studies evaluating vitamin D supplementation in pregnancy or early childhood for preventing childhood asthma have yielded inconclusive results. Previous systematic reviews of vitamin D for asthma prevention…
View details →DOI: 10.1002/14651858.cd013396.pub2 Negative / Null Result ReportOpen accessMedicine
Lang X, Zhao Y, Zhu Y et al. · 2025 · Risk management and healthcare policy
Background To assess the consequence of different degrees of missing primary endpoint data for randomized controlled trials and to find the influence factors. Methods PubMed, Cochrane Library, EMBASE and ClinicalTrials.gov were searched up…
View details →DOI: 10.2147/rmhp.s511449 Negative / Null Result ReportMedicine
Grillo AR · 2025 · American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
Depression is a major public health problem with a continued need to uncover its etiology. Current models of depression contend that gene-by-environment (G × E) interactions influence depression risk, and further, that depression is…
View details →DOI: 10.1002/ajmg.b.33000 Negative / Null Result ReportMedicine
Buchta C, Aberle SW, Allerberger F et al. · 2023 · The Lancet. Microbe
Background The aim of external quality assessment (EQA) schemes is to evaluate the analytical performance of laboratories and test systems in a near-to-real-life setting. This monitoring service provides feedback to participant…
View details →DOI: 10.1016/s2666-5247(23)00286-0 Negative / Null Result ReportOpen accessMedicine
Struja T, Hansen LH, Matos J et al. · 2026 · BMJ open
Importance Clinical trials have produced inconclusive results regarding the optimal glucose range for a patient with sepsis in the intensive care unit (ICU) receiving insulin treatment. Objective To investigate the optimal glucose range in…
View details →DOI: 10.1136/bmjopen-2025-104916 Negative / Null Result Report
Droste MJ, Remeijer M, Planqué R et al. · 2024 · Preprint
A bstract In isothermal chemical reaction networks, reaction rates depend solely on the reactant concentrations setting their thermodynamic driving force. Living cells can, in addition, alter reaction rates in their enzyme-catalysed…
View details →DOI: 10.1101/2024.07.13.603363 Negative / Null Result ReportOpen accessMedicine
Reiner M, Drobińska H, Miciak M et al. · 2026 · Cancer management and research
Background Thyroid cancer (TC) is the most commonly diagnosed endocrine malignancy, with rising global incidence. Current diagnostic techniques, including ultrasound and fine-needle aspiration biopsy (FNAB), often yield inconclusive…
View details →DOI: 10.2147/cmar.s571308 Negative / Null Result ReportMedicine
Wasmuth HH, Færden AE · 2024 · Updates in surgery
The paucity of prospective data on the subject of Watch and Wait for rectal cancer prompted the implementation of Norwait, a population-based study including rectal cancer patients after neoadjuvant therapy. The aim of the study was to…
View details →DOI: 10.1007/s13304-024-01941-0 Negative / Null Result ReportMedicine
Phillips E, Ngure FM, Kassim N et al. · 2025 · The American journal of clinical nutrition
Background Linear growth faltering continues to negatively affect children in low- and middle-income countries and is associated with poor cognitive, developmental, and educational outcomes. Laboratory and observational data suggest that…
View details →DOI: 10.1016/j.ajcnut.2024.11.022 Negative / Null Result ReportOpen accessMedicine
Otero Castro V, Scales DC, Angriman F · 2025 · Critical care explorations
Objectives We sought to estimate the association between chronic use of renin-angiotensin system inhibitors and acute kidney injury requiring renal replacement therapy in critically ill adult patients with sepsis. Design Population-based…
View details →DOI: 10.1097/cce.0000000000001304 Negative / Null Result ReportOpen accessMedicine
Lyons M, Lahuerta-Marin A, Clarke J et al. · 2025 · Irish veterinary journal
Bovine Viral Diarrhoea Virus (BVDV), Border Disease Virus (BDV), and Bovine Herpesvirus-1 (BoHV-1, the cause of Infectious Bovine Rhinotracheitis, IBR), are economically important endemic viruses in ruminant livestock in the United Kingdom…
View details →DOI: 10.1186/s13620-025-00292-5 Negative / Null Result ReportMedicine
Zeng QB, Zou DC, Huang XB et al. · 2025 · Journal of affective disorders
Background Electroconvulsive therapy (ECT) is a commonly used alternative for treatment-resistant depression (TRD). Although esketamine has a rapid pharmacological antidepressant action, it has not been studied as an ECT anesthetic. The…
View details →DOI: 10.1016/j.jad.2024.09.038 Negative / Null Result ReportOpen accessMedicine
Solodjankina A, Kratovska A, Ponomarjova S et al. · 2024 · Medicina (Kaunas, Lithuania)
Background and Objectives : Primary hyperparathyroidism (pHPT) is a common endocrine disorder caused by excessive production of parathyroid hormone (PTH) leading to elevated calcium levels. Diagnosis is primarily based on biochemical…
View details →DOI: 10.3390/medicina60030507 Negative / Null Result ReportMedicine
Zein SE, Tande AJ, Carr CM et al. · 2024 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Background Diagnostic methods for native vertebral osteomyelitis (NVO) often yield inconclusive results. Image-guided spine biopsies for culture are specific but diagnose NVO in only 50% of cases. Pre-exposure to antimicrobials further…
View details →DOI: 10.1007/s10096-024-04951-3 Negative / Null Result ReportMedicine
Neubauer FB, Wagner FL, Lörwald A et al. · 2024 · BMC medical education
It has been difficult to demonstrate that interprofessional education (IPE) and interprofessional collaboration (IPC) have positive effects on patient care quality, cost effectiveness of patient care, and healthcare provider satisfaction.…
View details →DOI: 10.1186/s12909-024-05590-0 Negative / Null Result ReportMedicine
Huish S, Sinha S · 2024 · Current opinion in nephrology and hypertension
Purpose of review Vascular and valvular calcification are associated with cardiovascular morbidity and mortality in people with chronic kidney disease (CKD). Uncertainty exists regarding therapeutic strategies to attenuate calcification.…
View details →DOI: 10.1097/mnh.0000000000000985 Negative / Null Result Report
Jhaveri k, Mai N, Anjos CHd et al. · 2024 · Preprint
Abstract After disease progression on endocrine therapy (ET) plus a CDK4/6 inhibitor, there is no standardized sequence for subsequent treatment lines for estrogen receptor positive (ER+) metastatic breast cancer (MBC). CDK4/6i retrial as…
View details →DOI: 10.21203/rs.3.rs-4237867/v1 Negative / Null Result ReportOpen accessMedicine
Needle R, Yu Y, Soualhine H et al. · 2025 · Biomedicines
Background/Objectives : The diagnosis of Mycobacterium tuberculosis complex (MTBC) and nontuberculous mycobacterial (NTM) infections is accomplished by three main diagnostics methods: smear microscopy, culture, and molecular testing.…
View details →DOI: 10.3390/biomedicines13102416 Negative / Null Result ReportOpen accessMedicine
Kirby C, Baldwin JA, Elwell K et al. · 2026 · Healthcare (Basel, Switzerland)
Background The literature shows inconclusive results from utilizing motivational interviewing (MI) in indigenous populations to address early childhood caries (ECC). Great Beginnings for Healthy Native Smiles (GBHNS) (NIDCR U01DE028508), a…
View details →DOI: 10.3390/healthcare14081059 Negative / Null Result Report
Fan J, Zeng F, Zhong H et al. · 2024 · Preprint
Abstract Cigarette smoking is posited as a potential factor in disrupting the balance of the human gut microbiota. However, existing studies with limited sample size have yielded inconclusive results. Here, we assessed the association…
View details →DOI: 10.21203/rs.3.rs-4274545/v1 Methods Dead-EndMedicine
Reis da Silva T · 2024 · British journal of community nursing
Aim This study reviews research into the effects of the supplementation of B12 in the prevention and recovery of mental illness, and the potentiation of psychotropic medication. Methodology This literature review follows a systematic…
View details →DOI: 10.12968/bjcn.2024.29.3.137 Negative / Null Result ReportOpen accessMedicine
Zhang Y, Baharani J, Ajayi B et al. · 2025 · BMC nephrology
Background Fibrillary glomerulonephritis (FGN) is a rare immune complex-mediated glomerulonephritis characterised by the deposition of anomalous fibrillary structures within the glomeruli. The prognosis for patients with FGN is usually…
View details →DOI: 10.1186/s12882-025-04187-z 