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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21742 results · page 642 of 725

Negative / Null Result ReportMedicine

Comparative evaluation of irrigation techniques on dentin nanohardness, flexural strength, and chemical composition: an in vitro study.

Ahmed, AbuMostafa · 2026 · Scientific reports

This investigation sought to evaluate the comparative influence of different irrigation activation protocols-ultrasonic, sonic, XP-Endo Finisher, and manual dynamic activation (MDA)-on the nanohardness, elastic modulus, flexural strength,…

View details →DOI: 10.1038/s41598-026-45610-1
Negative / Null Result ReportMedicine

The impact of preoperative anticoagulant administration on postoperative coagulation function and blood loss following posterior lumbar interbody fusion: a case-control study.

Zhan, Hao, Li et al. · 2026 · Frontiers in medicine

Currently, there are few reports on the impact of preoperative anticoagulant administration on perioperative coagulation function and blood loss. Therefore, this study observed the effects of preoperative anticoagulant administration on…

View details →DOI: 10.3389/fmed.2026.1753809
Negative / Null Result ReportMedicine

Motor coordination in school-aged children with different nutritional statuses following a non-immersive virtual reality intervention.

Da Silva Souza, De Souza, Dos Santos et al. · 2026 · Frontiers in public health

Children with low motor coordination tend to engage in less physical activity. They are more likely to gain weight, establishing a bidirectional relationship, as weight gain may further restrict their participation in physical activity.…

View details →DOI: 10.3389/fpubh.2026.1779788
Negative / Null Result ReportMedicine

[The Effect of BMI on the Mobilization of Peripheral Blood Hematopoietic Stem Cells in Healthy Donors].

Liang, Zhu, Han et al. · 2026 · Zhongguo shi yan xue ye xue za zhi

To explore the effect of body mass index (BMI) on the efficiency of hematopoietic stem cell (HSC) mobilization. A retrospective analysis was conducted on the clinical data of 158 healthy donors who underwent peripheral blood HSC…

View details →DOI: 10.19746/j.cnki.issn.1009-2137.2026.01.025
Negative / Null Result ReportMedicine

Cumulative input sensitivity predicts both attenuation and stability of lexically guided perceptual learning.

Cummings, Hodges, Theodore · 2026 · Psychonomic bulletin & review

Listeners can use lexical information to accommodate ambiguity in speech input. Some evidence suggests that lexically guided perceptual learning persists over time. However, other evidence suggests that lexically guided perceptual learning…

View details →DOI: 10.3758/s13423-026-02862-2
Negative / Null Result ReportMedicine

Histopathological evaluation of local effects of radioactive iodine seeds in axillary lymph nodes in clinically node-positive breast cancer treated with neoadjuvant systemic therapy.

van Amstel, Simons, Kooreman et al. · 2026 · Breast (Edinburgh, Scotland)

In clinically node-positive (cN+) patients, radioactive iodine ( 125 I) seeds can be considered to mark metastatic axillary lymph nodes before neoadjuvant therapy (MARI-procedure) but potential therapeutic effects remain unclear. This…

View details →DOI: 10.1016/j.breast.2026.104746
Negative / Null Result ReportMedicine

Risk Factors Associated with Mortality in Nosocomial Stenotrophomonas maltophilia Pneumonia: A Single-Center Retrospective Study.

Yıldız, Top, Yıldız et al. · 2026 · Mediterranean journal of hematology and infectious diseases

Stenotrophomonas maltophilia ( S. maltophilia ) is a multidrug-resistant pathogen frequently isolated in hospital-acquired pneumonia and represents a significant clinical challenge. This study aimed to investigate the risk factors…

View details →DOI: 10.4084/mjhid.2026.018
Short NoteMedicine

DNA repair-associated nucleases induce double-strand breaks following sequential exposure to UVA1 and UVB.

Narimichi, Komaki, Suzuki et al. · 2026 · Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

Solar UV comprises UVA and UVB; each exerts distinct biological effects, while their combined impact is not yet fully understood. We previously reported that human keratinocytes exposed to UVA1 followed by UVB irradiation exhibited severe…

View details →DOI: 10.1007/s43630-026-00874-4
Negative / Null Result ReportMedicine

Inpatient Opioid Use in Head and Neck Microvascular Free Flap Reconstruction.

Timothee, Bliss, Blumenthal et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

The primary objective is to determine whether patients undergoing osseous microvascular free flap reconstruction of head and neck defects have higher inpatient pain requirements than those undergoing nonosseous reconstruction. Secondary…

View details →DOI: 10.1002/ohn.70200
Negative / Null Result ReportMedicine

The effect of horticultural activity program on internet addiction, social skills, and stress levels in children: A randomized controlled trial.

Kacar, Ayaz-Alkaya · 2026 · Journal of pediatric nursing

Internet addiction is a growing problem among children and adolescents. Pathological internet use may lead to psychological and social issues. More effective and innovative interventions are needed to promote the mental health of children.…

View details →DOI: 10.1016/j.pedn.2026.02.035
Negative / Null Result ReportMedicine

Effect of titanium dioxide nanotubes in Ca(OH)2-based intracanal medicaments on odontoblast-like cells.

Lopes, Costa, Nociti Junior et al. · 2026 · Brazilian oral research

This study investigated the effects of incorporating 3wt% titanium dioxide nanotubes (nTiO2) into calcium hydroxide [Ca(OH)2]-based intracanal medicament (ICM) formulations on the proliferation, viability, and mitochondrial metabolic…

View details →DOI: 10.1590/1807-3107bor-2026.vol40.002
Negative / Null Result ReportMedicine

Effect of Tranexamic Acid Administration on the State of Pial Arterial Vessels in Rats with Acute Hemorrahage and Hypothermia.

Melnikova · 2025 · Bulletin of experimental biology and medicine

Using in vivo microscopy, changes in the diameter of pial arterial microvessels were studied in rats with modeled moderate acute blood loss followed by whole-body cooling against the background of a single administration of tranexamic acid…

View details →DOI: 10.1007/s10517-026-06603-2
Negative / Null Result ReportMedicine

The Effect of Anti-TNF Group Drugs on Thyroid Function in Patients with ‎Rheumatoid Arthritis and Ankylosing Spondylitis.

Tuncekin, Toprak · 2026 · Iranian journal of immunology : IJI

Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are chronic autoimmune inflammatory disorders in which TNF-α plays a key role. Anti-TNF agents are widely used in the management of these diseases. Since TNF-α is also…

View details →DOI: 10.22034/iji.2026.107743.3081
Negative / Null Result ReportMedicine

Organic fertilization shapes diazotrophic microbiomes in legume and grass rhizospheres of the Qinghai-Tibet Plateau.

Shen, Yan, Yan et al. · 2026 · Journal of environmental sciences (China)

Diazotrophs play a crucial role within the rhizosphere by fixing atmospheric nitrogen and promoting plant growth. However, the diversity of diazotrophic communities and the influences of human activity are largely unclear. This study…

View details →DOI: 10.1016/j.jes.2025.07.031
Negative / Null Result ReportMedicine

Vitamin D Status and Its Relationship with Platelet Parameters in Young Adults: Evidence from a Cross-Sectional Study.

Uludag, Uludag · 2026 · Current medicinal chemistry

Recently, there has been growing interest in the roles of vitamin D and certain platelet characteristics, such as mean platelet volume (MPV). However, the influence of vitamin D levels on these platelet traits is still under discussion.…

View details →DOI: 10.2174/0109298673427124251210100806
Negative / Null Result ReportMedicine

Effectiveness of transcranial direct current stimulation (tDCS) on attention and memory biases in individuals with post-traumatic stress disorder (PTSD): a randomized, single-blind, parallel-group study.

Estaji, Ahmadizadeh · 2026 · Journal of psychiatric research

Based on neurocognitive models, the development and maintenance of post-traumatic stress disorder (PTSD) are correlated with cognitive biases, including attention and memory biases, which are associated with imbalanced activation of…

View details →DOI: 10.1016/j.jpsychires.2026.02.039
Negative / Null Result ReportMedicine

Tongue strength and endurance in relation to oral cavity morphology among children with Down syndrome in the permanent dentition period.

Maureen, Budiardjo, Wahono · 2026 · Journal of the Indian Society of Pedodontics and Preventive Dentistry

Down syndrome is a genetic condition caused by trisomy 21, often accompanied by orofacial hypotonia and anomalies in stomatognathic development. A hypotonic tongue may alter oral cavity morphology, particularly palatal depth, anterior…

View details →DOI: 10.4103/jisppd.jisppd_489_25
Negative / Null Result ReportMedicine

Amyotrophic Lateral Sclerosis: The State of the Art on Treatments and the Therapeutic Role of the Intestinal Microbiome in Human Studies.

Ptáček, Musil, Guarnieri et al. · 2026 · International journal of molecular sciences

Amyotrophic lateral sclerosis (ALS) is a common neurodegenerative disorder; to date, there is no long-term effective treatment. Recently, a relationship has been discovered between the human intestinal microbiome and the pathogenesis of…

View details →DOI: 10.3390/ijms27041655