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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19915 results in Negative / Null Result Report · page 642 of 664

Negative / Null Result ReportMedicine

Impact of SARS-CoV-2 infection history on the clinical features and outcomes of patients with recurrent pulmonary tuberculosis: a retrospective case-control study.

Tang, Mi, Xue et al. · 2026 · Annals of medicine

The impact of prior SARS-CoV-2 infection on the clinical course of recurrent pulmonary tuberculosis (TB) remains poorly defined. This study aimed to compare clinical features, radiographic evolution, and outcomes in recurrent TB patients…

View details →DOI: 10.1080/07853890.2026.2683160
Negative / Null Result ReportMedicine

Association Between Temporomandibular Joint Morphology and Mandibular Growth in Adolescents With Facial Asymmetry: An Magnetic Resonance Imaging and Cone-Beam Computed Tomography Study.

Wang, Guo · 2026 · The Journal of craniofacial surgery

To investigate the growth and developmental characteristics of the temporomandibular joint (TMJ) in adolescents with facial asymmetry and its relationship with mandibular morphological changes. A total of 20 patients aged 8 to 20 years…

View details →DOI: 10.1097/scs.0000000000013021
Negative / Null Result ReportMedicine

MRI-based volumetric and histogram analysis of parotid and submandibular glands in hypertensive patients: a retrospective study.

Kotanlı, Yılmaz, Dogan · 2026 · BMC oral health

The aim of this retrospective study is to evaluate the volumetric and histogram-based characteristics of the parotid and submandibular salivary glands in patients with hypertension compared with healthy controls. Magnetic Resonance images…

View details →DOI: 10.1186/s12903-026-08727-3
Negative / Null Result ReportMedicine

Choledochoduodenostomy versus transpapillary stent by endoscopic retrograde cholangiopancreatography for preoperative biliary drainage before pancreatoduodenectomy: a French multicenter retrospective cohort study.

Belfil, Diai, Gonzalez et al. · 2026 · Surgical endoscopy

 Few studies have compared the different types of endoscopic biliary drainage, particularly endoscopic retrograde cholangiopancreatography (ERCP) versus Endoscopic ultrasound guided-Choledochoduodenostomy (EUS-CD), for jaundice caused…

View details →DOI: 10.1007/s00464-026-12722-8
Negative / Null Result ReportMedicine

Prospective Methodology Results in Higher Rates of Reported Complications Following Pediatric ACL Reconstruction.

Martin, Ellis, Agonias et al. · 2026 · Journal of pediatric orthopedics

The incidence of pediatric anterior cruciate ligament reconstructions (ACLR) has drastically increased over the last 20 years. Previous studies have sought to characterize postoperative complications, but few have utilized a prospective,…

View details →DOI: 10.1097/bpo.0000000000003359
Negative / Null Result ReportMedicine

The Effect of Guided Imagery and Music with Sasando Music on Anxiety among Ischemic Stroke.

Mbau, Handayani, Kusumaningrum · 2026 · Iranian journal of nursing and midwifery research

Guided Imagery and Music (GIM) interventions reduced the anxiety in many clinical settings. Traditional music pictures the emotion of specific culture. No interventional study was found in reducing anxiety among ischemic stroke patients…

View details →DOI: 10.4103/ijnmr.ijnmr_23_23
Negative / Null Result ReportMedicine

Multiple Genetic Origins of Non-Native, Self-Sustaining Rainbow Trout Oncorhynchus mykiss in Streams in Baden-Württemberg, Germany.

Koene, Jacobs, Bartolin et al. · 2026 · Evolutionary applications

Introduced in the late 19th Century, Oncorhynchus mykiss (rainbow trout) has been stocked historically in streams throughout Baden-Württemberg, Germany, and some populations have become self-sustaining with unclear impact on native…

View details →DOI: 10.1111/eva.70271
Negative / Null Result ReportMedicine

Extracellular vesicle microRNA signature as a highly accurate diagnostic biomarker for human brucellosis.

Wu, Zhang, He et al. · 2026 · Frontiers in cellular and infection microbiology

Brucellosis remains an important public health problem globally. Rapid and accurate diagnosis is crucial for the treatment of brucellosis. However, current diagnostic methods for brucellosis are limited, posing significant clinical…

View details →DOI: 10.3389/fcimb.2026.1806232
Negative / Null Result ReportMedicine

Similar secondary patellar resurfacing but higher tibial revision risk with posterior stabilized versus medial pivot total knee arthroplasty: A registry analysis.

Pflüger, Pedrazzini, Jud et al. · 2026 · Journal of experimental orthopaedics

Patellar complications are among the most frequent causes of revision after primary total knee arthroplasty (TKA). The primary study objective is to compare the rate of secondary patellar resurfacing between medial pivot (MP) and posterior…

View details →DOI: 10.1002/jeo2.70751
Negative / Null Result ReportMedicine

Long-Term Outcomes After Catheter-Directed Thrombolysis or Mechanical Thrombectomy in Intermediate-High-Risk Pulmonary Embolism: A Propensity-Matched Analysis From a TriNetX Database.

Giorgi, Bertoletti, Luis et al. · 2026 · Pulmonary circulation

Catheter-directed thrombolysis (CDL) and mechanical thrombectomy (MT) are increasingly used for intermediate-high-risk pulmonary embolism (PE), yet comparative long-term outcomes remain uncertain. We aimed to compare the effectiveness and…

View details →DOI: 10.1002/pul2.70329
Negative / Null Result ReportMedicine

Endoscopic Versus Open Carpal Tunnel Release in Obese and Nonobese Patients.

Salib, Sanchez, Diatta et al. · 2026 · Journal of hand surgery global online

This study compared postoperative complications and revision rates following endoscopic versus open carpal tunnel release (CTR) in obese and nonobese patients. A 2010-2022 national administrative database was queried to identify adults…

View details →DOI: 10.1016/j.jhsg.2026.101053
Negative / Null Result ReportMedicine

A TriNetX global collaborative network retrospective cohort study on the impact of COVID-19 vaccination on juvenile idiopathic arthritis.

Yong, Chiang, Yang et al. · 2026 · Scientific reports

The objective is to determine the Impact of COVID-19 Vaccination and Medical Utilization in Juvenile Idiopathic Arthritis (JIA) patients. Our study retrieved data from the US Collaborative Network in TriNetX between January 1st, 2020, and…

View details →DOI: 10.1038/s41598-026-52548-x
Negative / Null Result ReportMedicine

Does Tibial Tunnel Placement Affect Postoperative Function and Isokinetic Outcomes in Patients Undergoing Anatomical Single-Bundle Anterior Cruciate Ligament Reconstruction with Hamstring Autograft?

Arslantaş, Deveci, Ozdemir et al. · 2026 · The journal of knee surgery

Tunnel malposition is a frequent complication of anterior cruciate ligament (ACL) reconstruction. We evaluated whether the tibial tunnel location of patients who underwent anatomical single-bundle ACL reconstruction with hamstring tendons…

View details →DOI: 10.1055/a-2886-7914
Negative / Null Result ReportMedicine

Comparison of early-onset and average-onset colorectal cancer in Saudi Arabia: A multicenter retrospective cohort study.

Alessy, Al-Bawardy, Alabdullah et al. · 2026 · Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

Although overall colorectal cancer (CRC) incidence has stabilized or declined in some regions, early-onset CRC (EO-CRC) is increasing in many countries. We aimed to compare EO-CRC with average-onset CRC (AO-CRC) to inform screening and…

View details →DOI: 10.4103/sjg.sjg_51_26
Negative / Null Result ReportMedicine

Thermal ablation versus hepatectomy in patients with liver metastases from RAS-mutated colorectal cancer.

Wen, Zhou, Chen et al. · 2026 · Journal of cancer research and therapeutics

To compare the efficacy and safety of thermal ablation therapy and hepatectomy in patients with RAS-mutated colorectal liver metastases (CRLMs). A 1:1 propensity score matching (PSM) analysis was conducted to categorize patients into…

View details →DOI: 10.4103/jcrt.jcrt_1515_25
Negative / Null Result ReportMedicine

Large Language Models and Metabolic Bariatric Surgery: A Pilot Concordance Study Between ChatGPT and Multidisciplinary Team Recommendations.

Ahmed, Bhanderi, Westerman et al. · 2026 · Obesity surgery

Operation selection in metabolic surgery is a complex decision making process led by a multidisciplinary team that integrates multiple anatomical, clinical, metabolic and psychosocial aspects. The ability of large language models (LLMs)…

View details →DOI: 10.1007/s11695-026-08777-0
Negative / Null Result ReportMedicine

Stool Microbiota, Metabolites, and Fecal Incontinence in Women.

Arya, Kashyap, Carnes et al. · 2026 · Urogynecology (Philadelphia, Pa.)

Stool metabolites influencing gut motility and sensation may contribute to fecal incontinence (FI). The objective of this study was to test whether FI is associated with higher levels of butyrate and Clostridiales taxa in stool. Stool…

View details →DOI: 10.1097/spv.0000000000001885
Negative / Null Result ReportMedicine

Comparative effectiveness of tirzepatide versus GLP-1 receptor agonists on the risk of venous thromboembolism in patients with obesity: a real-world cohort study.

Wu, Lee, Huang et al. · 2026 · Frontiers in medicine

Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), represents a major cause of morbidity and mortality in patients with obesity. Although glucagon-like peptide-1 receptor agonists (GLP-1 RAs)…

View details →DOI: 10.3389/fmed.2026.1820366