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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19915 results in Negative / Null Result Report · page 638 of 664

Negative / Null Result ReportMedicine

Comparison of fibrin glue posterior fixation and omentopexy in laparoscopic sleeve gastrectomy: a propensity score-matched analysis.

Liang JL, OuYang SR, Liu ZX et al. · 2026 · Updates in surgery

Laparoscopic sleeve gastrectomy (LSG) is currently the most commonly performed weight loss surgery. Omentopexy is believed to help reduce the risk of postoperative nausea and vomiting (PONV), bleeding, gastric leakage, and gastroesophageal…

View details →DOI: 10.1007/s13304-026-02675-x
Negative / Null Result ReportOpen accessMedicine

Hemodynamic effects of high frequency oscillatory ventilation versus conventional mechanical ventilation in term neonates with persistent pulmonary hypertension: a single-center randomized trial.

El Amrousy D, Koura H, Abdou N et al. · 2026 · Italian journal of pediatrics

Background We aimed to evaluate the hemodynamics in full-term neonates with persistent pulmonary hypertension (PPH) on high frequency oscillatory ventilation (HFOV) versus conventional mechanical ventilation (CMV). Methods This trial was…

View details →DOI: 10.1186/s13052-026-02272-z
Negative / Null Result ReportMedicine

The effect of video assisted instruction on central venous catheter application skills, anxiety and satisfaction in nursing students: a randomised controlled study.

Koç G, Yüce Başaran HD, Yavuz B et al. · 2026 · BMC medical education

Objective This study aimed to evaluate the effect of video-assisted instruction on central venous catheter (CVC)-related psychomotor skills (blood collection, drug administration, and dressing care), anxiety levels, and student…

View details →DOI: 10.1186/s12909-026-09532-w
Negative / Null Result Report

Lower urinary tract symptoms are elevated with depression in Japanese male

Yamazaki M, Ninomiya S, Hashizume A et al. · 2026 · Preprint

Abstract Background About half of both men and women have lower urinary tract symptoms, and aging is reported to have a significant impact on these symptoms. Lifestyle-related diseases such as diabetes, hypertension, and metabolic syndrome…

View details →DOI: 10.21203/rs.3.rs-9310496/v1
Negative / Null Result ReportOpen accessMedicine

Large language models perpetuate bias in palliative care: Development and analysis of the Palliative Care Adversarial Dataset (PCAD).

Akhras N, Antaki F, Mottet F et al. · 2026 · PLOS digital health

Bias and inequity in palliative care disproportionately affect marginalised groups. Large language models (LLMs), such as GPT-4o, hold potential to enhance care but risk perpetuating biases present in their training data. This study aimed…

View details →DOI: 10.1371/journal.pdig.0001451
Negative / Null Result ReportOpen accessMedicine

Enhanced efficacy of tylvalosin tartrate enteric-coated granules against <i>Mycoplasma hyopneumoniae</i> in pigs: <i>in vitro</i> activity and clinical dosage optimization.

Li J, Zhou X, Wang W et al. · 2026 · Frontiers in microbiology

Background Mycoplasma hyopneumoniae (Mhp), the etiological agent of enzootic pneumonia in pigs, poses significant challenges to swine production. This study evaluated the anti-Mhp efficacy of a novel enteric-coated granules of tylvalosin…

View details →DOI: 10.3389/fmicb.2026.1809157
Negative / Null Result ReportOpen accessMedicine

Comparison of the Effects of Local Heat and Massage Using the Flick Application on Pain Caused by Vitamin K Injection in Neonates.

Momenisoroshk J, Sadeghi T, Seyedbagheri S · 2026 · Pediatric health, medicine and therapeutics

Purpose Healthy neonates experience pain during procedures such as vitamin K injections. Pain adversely affects the neonate, so it is important to control it. This study compared the effects of local heat and massage using the flick…

View details →DOI: 10.2147/phmt.s559432
Negative / Null Result ReportOpen accessMedicine

The Effect of the combination therapy of statin and dapagliflozin, a selective inhibitor of sodium_glucose Co-transporter type 2, in the treatment of Ischemic heart disease with heart failure: A randomized controlled trial.

Abdelkader AM, Osama H, Hassan ES et al. · 2026 · European journal of clinical pharmacology

Purpose Gliflozins (SGLT2 inhibitors) and statins are key treatments commonly used in patients with ischemic heart failure. Although both are well known for diminishing cardiovascular risk and heart failure-related mortality, the possible…

View details →DOI: 10.1007/s00228-026-04050-6
Negative / Null Result ReportMedicine

PERFECT MATCH: can you fit the personality to the service? Understanding personality traits of hospital pharmacists in different clinical services-an observational study.

Brideau S, Duong T, Nacevska I et al. · 2026 · The International journal of pharmacy practice

Objectives The objective of the study was to evaluate if using a validated psychometric test, The Big Five Personality Test, would identify an association between personality traits among hospital pharmacists and certain clinical services.…

View details →DOI: 10.1093/ijpp/riaf105
Negative / Null Result ReportOpen accessMedicine

The abilities of nitrogen-fixing bacteria to produce siderophores affect their promoting effects on cucumber growth and antiphytopathogenic fungus activities.

Wang EX, Li J, Zhang YT et al. · 2026 · Frontiers in microbiology

Introduction Many nitrogen-fixing bacteria (NFB) can synthesize siderophores. However, the contribution of NFB siderophore synthesis to plant growth has not been evaluated, and its impact on NFB's antifungal activity remains unclear.…

View details →DOI: 10.3389/fmicb.2026.1756337
Negative / Null Result ReportOpen accessMedicine

Oral Health and Idiopathic Female Infertility: A Potential Association.

Kovács D, Boda K, Badó A et al. · 2026 · Oral health & preventive dentistry

Purpose To explore the possible link between periodontal and dental health and idiopathic female infertility in South East Hungary, along with identifying relevant sociodemographic factors. Methods and materials The study included women…

View details →DOI: 10.3290/j.ohpd.c_2670
Negative / Null Result ReportOpen accessMedicine

Effect of implant position on clinical outcomes of two implant overdentures: a 3-year randomized clinical trial.

Raafat MH, Mourad KE, Elsyad MA · 2026 · BMC oral health

Background Reviewing the literature, the optimal implant position for 2-implant retained mandibular overdentures, which would be associated with improved peri-implant tissues, higher retention values, and better patient satisfaction,…

View details →DOI: 10.1186/s12903-026-08441-0
Negative / Null Result ReportOpen accessMedicine

Comparison of physico-mechanical properties of 3D-printed resins used as permanent indirect restoration materials.

Arıkan M, Akarsu S · 2026 · Biomaterial investigations in dentistry

Objective To compare the physico-mechanical properties (microhardness, surface roughness, and flexural strength) of permanent 3D-printed dental resins with those of a resin nanoceramic computer-aided design and computer-aided manufacturing…

View details →DOI: 10.2340/biid.v13.46113
Negative / Null Result ReportOpen accessMedicine

Antibacterial and anti-biofilm effects of postbiotic mediator derived from <i>Jeotgal</i> isolate <i>Lactiplantibacillus plantarum</i> KMC12 against <i>Streptococcus mutans</i>.

Oh H, Kim J, Bai J · 2026 · Journal of oral microbiology

Background Dental caries, commonly known as tooth decay, is a progressive breakdown of tooth tissues caused by the biofilm-producing bacteria, Streptococcus mutans . S. mutans plays a primary role in the initiation and progression of…

View details →DOI: 10.1080/20002297.2026.2684130
Negative / Null Result ReportOpen accessMedicine

Empagliflozin enhances cisplatin activity in chemo-resistant EJ138 bladder cancer cells: The importance of anti-diabetic medications in cancer treatment.

Shariati S, Mohtadi S, Molavinia S et al. · 2026 · Scientific reports

Anti-diabetic medications have been found to reduce chemotherapy resistance. This study sought to investigate the role of Empagliflozin (Empa) as an anti-diabetic medication in reversing Cisplatin (Cis) resistance in EJ138 bladder cancer…

View details →DOI: 10.1038/s41598-026-49196-6
Negative / Null Result ReportOpen accessMedicine

Selected immunoendocrine and performance adaptations to upper-body plyometric training and β-alanine supplementation in male swimmers.

Gao H, Yu X, Guo Z · 2026 · Journal of the International Society of Sports Nutrition

Background Upper-body plyometric training (PT) enhances neuromuscular performance and power production. However, its application in swimming and its potential interaction with β-alanine (BA) supplementation remain largely unexplored.…

View details →DOI: 10.1080/15502783.2026.2679050
Negative / Null Result Report

Effects of Community-Based Nutrition Education on Maternal Knowledge, Attitudes, and Practices Regarding Childhood Nutrition in Ningi LGA, Nigeria: A Pre–Post intervention Study

Alhassan A · 2026 · Preprint

Abstract The study aims to assess the effects of community-based nutrition education program on childhood nutrition for children 6months − 5years. Finding from the study indicate that the analysis of 100% response at baseline data (N =…

View details →DOI: 10.21203/rs.3.rs-9520536/v1
Negative / Null Result ReportOpen accessMedicine

Age-Dependent Alterations of Chromosomal Passenger Complex Members During Implantation and Decidualization in the Mouse Uterus.

Golal E, Balci CN, Acar N · 2026 · Aging cell

Successful embryo development, acquisition of uterine receptivity, implantation, and decidualization during the peri-implantation window are essential events that ensure a healthy pregnancy. While ovarian aging has long been considered the…

View details →DOI: 10.1111/acel.70506
Negative / Null Result ReportMedicine

Evaluation of Point-of-Care Coagulation Measurement Systems for Activated Clotting Time and Partial Thromboplastin Time in Heparinized and Non-Heparinized Equine Blood.

Hobbs KJ, Ueda Y, Qu Y et al. · 2026 · Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

Objectives To compare the performance of one point-of-care activated clotting time (ACT) machine (Vet-Tube), one point-of-care activated partial thromboplastin time (aPTT) machine (Coagulation DX), and one bench-top ACT machine (Medtronic…

View details →DOI: 10.1111/vec.70127
Negative / Null Result ReportMedicine

Homemade Ultrasound Stand-Off Gel Pads: A Multi-Parameter Performance Study.

William MFGBMF, Jamil NAB, Leong SS et al. · 2026 · Australasian journal of ultrasound in medicine

Aim Stand-off gel pads made of natural ingredients may provide a low-cost option in clinical ultrasound imaging. This study investigated the performance and safety of homemade pads. Methods Thirty stand-off gel pads were made of aloe vera,…

View details →DOI: 10.1002/ajum.70044
Negative / Null Result ReportOpen accessMedicine

Evaluation of soluble transferrin receptor and malondialdehyde levels associated with ferroptosis in children with familial Mediterranean fever in remission.

Dogantan S, Keskin A, Yücel BB et al. · 2026 · Revista da Associacao Medica Brasileira (1992)

Objective Familial Mediterranean fever, an autoinflammatory disease, is characterized by recurrent stereotypic febrile attacks associated with an inflammatory syndrome. Malondialdehyde, a lipid peroxidation marker, and soluble transferrin…

View details →DOI: 10.1590/1806-9282.20252110
Negative / Null Result ReportMedicine

Impact of different treatment approaches on long-term refractive and visual outcomes in retinopathy of prematurity.

Kizilay O, Kunbaz A, Akarsu Acar OP et al. · 2026 · International journal of ophthalmology

Aim To evaluate the long-term refractive and visual outcomes in infants with retinopathy of prematurity (ROP) treated with intravitreal bevacizumab (IVB), laser photocoagulation (LPC), or combined IVB+LPC therapy, and to assess disease…

View details →DOI: 10.18240/ijo.2026.06.11
Negative / Null Result ReportOpen accessMedicine

Effects of different personal protective equipment on the cardiovascular system in a 6-minute walk test.

Masilamani PK, Muhammad NB, Sankaran RS et al. · 2026 · Clinics (Sao Paulo, Brazil)

Introduction During the Coronavirus Disease (COVID-19) pandemic, public and healthcare workers were recommended to use Personal Protective Equipment (PPE) to prevent the spread of infection. With the increased use of different types of…

View details →DOI: 10.1016/j.clinsp.2026.100994
Negative / Null Result ReportOpen accessMedicine

Midterm Quadriceps Strength Outcomes of Revision ACL Reconstructions Comparing Ipsilateral Extensor Mechanism Autografts and Hamstring Tendon Autografts.

Zavala P, Eggleston GG, Greufe NA et al. · 2026 · Orthopaedic journal of sports medicine

Background Primary anterior cruciate ligament reconstructions (ACLRs) with extensor mechanism autografts (bone-patellar tendon-bone [BTB] or quadriceps tendon [QT]) have been reported to have lower quadriceps strength symmetry outcomes 6…

View details →DOI: 10.1177/23259671261451830
Negative / Null Result ReportOpen accessMedicine

Evaluation of occlusion and disocclusion time in immediately loaded implant overdentures retained by two splinted versus non-splinted interforaminal implants: A randomized clinical trial.

Refai OM, Abdelfattah Mohamed AM, Ali El-Fiky AM · 2026 · BMC oral health

Background Mandibular complete dentures often lack stability, leading to prolonged occlusion and disocclusion times. Immediate-loading implant overdentures can improve functional control, but evidence comparing splinted and non-splinted…

View details →DOI: 10.1186/s12903-026-08855-w
Negative / Null Result Report

Analysis of Characteristics of 115 Cases with Unexpected Antibodies and Exploration of Transfusion Strategies: A Retrospective Study

Wen¹ C, Tang¹ Y, Zhu¹ L et al. · 2026 · Preprint

Abstract Objective: To investigate the incidence and distribution characteristics of unexpected antibodies through a retrospective analysis of 115 positive cases and explore transfusion strategies for patients with unexpected antibodies.…

View details →DOI: 10.21203/rs.3.rs-9562251/v1