e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19915 results in Negative / Null Result Report · page 637 of 664

Negative / Null Result ReportOpen access

The SOS Pilot Study: a RCT of routine oxygen supplementation early after acute stroke—effect on recovery of neurological function at one week

Khalid Mustafa Ali (4461853), Christine Roffe (220471), Anushka Warusevitane (220475) et al. · 2011

Mild hypoxia is common after stroke and associated with poor long-term outcome. Oxygen supplementation could prevent hypoxia and improve recovery. A previous study of routine oxygen supplementation showed no significant benefit at 7 and 12…

Negative / Null Result ReportOpen access

Conflict duration on the flanker task (i.e., reaction time for each incongruent trial–reaction time for each congruent trial) pre- (white bar) and post-treatment (black bar) with OT or placebo.

Yuko Yoshimura (283970), Hirotoshi Hiraishi (283977), Mitsuru Kikuchi (140272) et al. · 2015

Two-way ANOVA (treatment × drug) failed to demonstrate any drug or treatment effects, and no significant interaction between these two factors was detected. Therefore, we failed to demonstrate any OT-related effect on…

View details →DOI: 10.1371/journal.pone.0116918.g004
Negative / Null Result ReportOpen access

Cutaneous sterile pyogranuloma/granuloma syndrome in a dog

SPATERNA, Andrea, MECHELLI A., SANTORO D. et al. · 2008

A case of canine cutaneous sterile pyogranuloma/granuloma syndrome (SPGS) with generalized asymmetrical alopecia and plaques is described. Results from histopathologic examination were suggestive of SPGS and failed to demonstrate any…

Negative / Null Result ReportOpen access

Visual impairment, aging and driving ability

Wood, Joanne M. · 2002

It has been suggested that over 90% of the sensory information for driving is visual. Despite this belief, traditional studies have failed to demonstrate that increased crash rates arise from impaired vision. However, more recent studies…

Negative / Null Result ReportOpen access

Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients.

Grimaud, Dominique, Berthier, Fréderic, Ichai, Carole et al. · 2009

International audienceOBJECTIVES: Traumatic brain injury (TBI) is still a major cause of mortality and morbidity. Recent trials have failed to demonstrate a beneficial outcome from therapeutic treatments such as corticosteroids,…

View details →DOI: 10.1007/s00134-008-1283-5
Negative / Null Result ReportOpen access

A pilot, double blind randomised controlled trial of prednisolone for women with recurrent miscarriage and raised uterine natural killer cell density [Abstract]

Dawood, Feroza, Farquharson, Roy G., Turner, M. A. et al. · 2011

Introduction: Multiple trials of immunotherapy for reproductive failure have failed to demonstrate significant benefit. A reason for this may be the lack of a test that selects which women will benefit from treatment. High density of…

View details →DOI: 10.1093/humrep/26.s1.34
Negative / Null Result ReportOpen access

Good laboratory practice: preventing introduction of bias at the bench

Macleod, Malcolm R.; id_orcid, Donnan, Geoffrey A., Traystman, RJ et al. · 2009

Background and Purpose—As a research community, we have failed to demonstrate that drugs which show substantial efficacy in animal models of cerebral ischemia can also improve outcome in human stroke. Summary of Review—Accumulating…

View details →DOI: 10.1038/jcbfm.2008.101
Negative / Null Result ReportOpen access

Early effect of moderate altitude stress on plasma potassium in the dog

Armand J. Gold, Jeanne Q. Barry, Frederick P. Ferguson · 1960

Exposure of dogs to a simulated altitude of 30,000 feet for 30 minutes resulted in marked respiratory alkalosis and hypokalemia. The data failed to demonstrate, however, the appearance of the early transient hyperkalemic response which has…

View details →DOI: 10.1152/jappl.1960.15.1.37
Negative / Null Result ReportOpen access

Is there any role for the Hydroxychloroquine (HCQ) in refractory obstetrical antiphospholipid syndrome (APS) treatment?

Botta, Angela, De Carolis, S, Botta, A. et al. · 2015

The best therapy regimen for refractory obstetrical antiphospholipid syndrome remains to be determined. Additional treatments with steroids, plasma exchanges and immunoglobulins failed to show any beneficial effect. We present a case of a…

View details →DOI: 10.1016/j.autrev.2015.04.010
Negative / Null Result ReportOpen access

Carbon dioxide-induced amnesia in the cockroach Periplaneta americana

Wahlsten, Douglas, NC DOCKS at The University of North Carolina at Greensboro · 1968

Cockroaches (Periplaneta americana) learned to passively avoid electric shock in a two-compartment box after a single training trial. However, Ss exposed to CO2 gas immediately after the training trial failed to show retention of the…

Negative / Null Result ReportOpen access

Risk of dementia hospitalisation associated with cardiovascular risk factors in midlife and older age: the Atherosclerosis Risk in Communities (ARIC) study

Mosley, T H, Catellier, D, Sharrett, A R et al. · 2009

Cardiovascular risk factors are associated with a higher risk of developing dementia. Studies in older populations, however, have often failed to show this relationship. We assessed the association between cardiovascular risk factors…

View details →DOI: 10.17615/9nxm-j737