A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21363 results · page 635 of 713
Kathpalia A, Vlachos I, Hlinka J et al. · 2026 · Preprint
ABSTRACT Objective Finding: indicators of early response to antidepressant treatment in EEG signals recorded from patients suffering from major depressive disorder. Methods Functional brain connectivity networks based on weighted imaginary…
Ravenda S, Gerra MC, Barbetti M et al. · 2026 · Psychoneuroendocrinology
MicroRNAs (miRNAs) have attracted great interest as potential biomarkers in several research domains, including acute and chronic stress conditions. While most of these studies focused on circulating blood miRNA levels, the investigation…
Lojek NM, Bostanci N, Henrique Borges P et al. · 2026 · Radiation research
Proton radiation is known to have detrimental neurological effects, but there is limited scientific understanding of these effects at the cellular and tissue levels. We leveraged our 3D in vitro cortical tissue model alongside 2D cortical…
Hu JC, Kapadia SN, Zhang H et al. · 2026 · JAMA health forum
Importance Buprenorphine is the most commonly prescribed medication for opioid use disorder, but rates of retention in treatment remain low. Prior authorization (PA) has been identified as a barrier to the administration of buprenorphine,…
Saud MA, Khamees Abed S, Shahooth MA et al. · 2026 · F1000Research
Background While ivermectin is a common antiparasitic drug used in veterinary medicine, the effects of repeated administration at therapeutic doses have not been well studied. Of particular interest is the impact of ivermectin on…
Zainuddin MS, Pamidi N, Azman AS et al. · 2026 · Redox report : communications in free radical research
Alzheimer's disease (AD) is a major global neurodegenerative disorder associated with high morbidity and mortality, yet current treatments remain largely symptomatic and ineffective in halting neurodegeneration. Growing evidence links…
Fukui S, Sumiyoshi R, Koga T et al. · 2026 · Drug discoveries & therapeutics
Idiopathic multicentric Castleman disease (iMCD) is a rare lymphoproliferative disease characterized by systemic inflammation. Although IL-6 receptor blockade with tocilizumab is an established treatment, Janus kinase (JAK) inhibition may…
Garabet W, Beckamp KH, Shabes P et al. · 2026 · VASA. Zeitschrift fur Gefasskrankheiten
Background: Supervised Exercise Therapy (SET) improves walking performance in patients with peripheral arterial disease (PAD) and intermittent claudication, yet implementation and adherence remain inconsistent. This study evaluated…
Mobasseri M, Vahabie AH, Jafari G et al. · 2026 · Brain imaging and behavior
Behavioral contagion is defined as the tendency of individuals to conform with others' behavior after observing them. Despite the important role that behavioral contagion plays in societies, its brain mechanism is still not fully…
Ptak A, Stefańska M · 2026 · Journal of clinical medicine
Background: The objective of this study was to assess the tension of selected postural muscles during the jaw-sucking movement in four body positions (standing position, all-fours position, lying on front, lying on the side). Material and…
Harding M, Case J, Knighton K et al. · 2026 · Preprint
Abstract Medical school has long been thought to have a potentially detrimental effect on the health of its students. We sought to understand if students experienced a decline in their cardiorespiratory physical fitness during their first…
Chowdhury M, Bustamante AV · 2026 · Health affairs (Project Hope)
Lawfully present noncitizen immigrants face persistent coverage gaps due to federal restrictions on Medicaid eligibility, including the five-year bar under the 1996 Personal Responsibility and Work Opportunity Reconciliation Act, and…
Yakasai AM, Maharaj SS, Danazumi MS · 2026 · American journal of physical medicine & rehabilitation
Objective This study evaluated the efficacy of endurance exercise on balance impairment and gait disturbance among individuals living with Human Immunodeficiency Virus (HIV)-related distal symmetrical polyneuropathy (DSPN). Design This was…
Peng J, Zou M, Ng ML et al. · 2025 · Preprint
Abstract Objective To investigate the therapeutic efficacy and application of different straw phonation exercise regimens as interventions for vocal fatigue. Methods One hundred and fourteen healthy adults aged 20–40 years with no organic…
Srinivasan VV, Ravikumar A, Ostrin LA · 2026 · Eye & contact lens
Purpose To determine the effects of contact lens-induced full-field and peripheral-field myopic defocus on choroid thickness and variation with time of day in young adults. Methods In this prospective, randomized, crossover study, 16…
Echizen T, Yusu S, Chiba U et al. · 2026 · Physical therapy research
Objectives This study aimed to compare the effects of repetitive peripheral magnetic stimulation (rPMS) and neuromuscular electrical stimulation (NMES) on hemodynamics and obtain basic data to verify the safety of rPMS in healthy adults.…
Esen Baris M, Guclu A, Guven S et al. · 2026 · BMC ophthalmology
Background Phenylephrine is widely used for pharmacological mydriasis in routine ophthalmic practice. While its vascular and pupillary effects are well established, its influence on anterior segment structures and intraocular inflammatory…
Dobsikova R, Marsalek P, Velisek J et al. · 2026 · Veterinarni medicina
This study assessed the effect of a 24-hour bath with praziquantel (2 and 4 mg/l) on grass carp ( Ctenopharyngodon idella ) by monitoring the haematological parameters, plasma biochemical profile, and oxidative stress indices. Fish were…
li y, pi a, sun z · 2026 · Preprint
Abstract Background The Diagnosis-Intervention Packet (DIP) is a data-driven prospective payment system designed to improve the allocation of medical resources and contain healthcare expenditures. This study examines whether the…
Lin Y, Luo S, Lu Q et al. · 2025 · Preprint
Abstract Background To evaluate the effects of ICL implantation on the corneal biomechanical parameters of patients with high myopia Methods Corneal biomechanical parameters were measured preoperatively and postoperatively in 110 eyes of…
Di̇ncer M, Canturk N, Dagalp R et al. · 2026 · Forensic science international
A signature is writing and/or signs that contain the signatory's personal characteristics and are used to indicate that people accept the authenticity of the formal and private transactions made by themselves in their daily lives and…
Koyama K, Hosono S · 2026 · Journal of strength and conditioning research
Abstract Koyama, K and Hosono, S. Comparison of the effects of barefoot and shod training on foot structure, muscle strength, and sensory function. J Strength Cond Res 40(5): 566-575, 2026-The aim of this study was to compare the effects…
Biguino B, Haigh ID, Dias JM et al. · 2025 · Scientific reports
Marine Heat Waves (MHWs) have been the focus of numerous studies due to the dramatic consequences they can have on coastal systems. However, Marine Cold Spells (MCSs) can also have harmful effects on the environment while play an important…
Cesna S, Bielinis A, Zvirblis T et al. · 2026 · Cardiology in the young
Objectives Despite the effectiveness of the surgical or percutaneous treatment of coarctation of the aorta, the presence of hypertension in these patients remains a common and concerning issue. This study was undertaken to explore the…
Andrés AI, Martín-Mateos MJ, D'Arrigo M et al. · 2026 · Food chemistry
This study evaluated the effects of high hydrostatic pressure (HHP)-treated white (WGP) and red grape pomace (RGP) on oxidative stability, volatile compounds, and polycyclic aromatic hydrocarbons (PAHs) in barbecued Frankfurter sausages.…
Kit-Anan W, Vaewpanich J, Anantasit N · 2026 · Children (Basel, Switzerland)
Background: Extubation failure increases morbidity and mortality. Non-invasive ventilation (NIV), including high-flow nasal cannula (HFNC), can reduce reintubation rates. Current practice often involves prophylactic use of NIV…
Teh WT, Chung J, Donoghue JF et al. · 2026 · Human reproduction (Oxford, England)
Study question Does endometrial gene expression change across consecutive cycles and after endometrial injury? Summary answer Although paired endometrial samples collected from the same woman across two consecutive cycles show greater…
Jafari A, Amani Beni S · 2026 · Maturitas
Background Myonectin is a myokine that regulates lipid metabolism, and levels are often reduced in obesity and insulin resistance. This study examined whether the timing of exercise influences myonectin and metabolic responses to…
Başaran R, Demirci H, Başaran TÖ et al. · 2026 · BMC geriatrics
Ramadan fasting involves prolonged daytime abstinence from food and fluid intake and may influence cardiovascular and physiological regulation. Although prior studies have examined metabolic and cardiovascular effects, evidence on…
Delling C, Kirchner M, May K et al. · 2026 · Parasites & vectors
Background Cryptosporidium parvum and Giardia duodenalis (assemblages A and B) are ubiquitously occurring protozoan parasites infecting a broad range of hosts. Co-infection with both parasites in suitable hosts have been reported, but…